نتائج البحث - "Shabih Shakeel"

المصدر: Nat Struct Mol Biol
Sijacki, T, Alcón, P, Chen, Z A, Mclaughlin, S H, Shakeel, S, Rappsilber, J & Passmore, L A 2022, ' The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination ', Nature Structural & Molecular Biology, vol. 29, no. 9, pp. 881-890 . https://doi.org/10.1038/s41594-022-00820-9Test

مصطلحات موضوعية: Fanconi Anemia, Polynucleotide 5'-Hydroxyl-Kinase, DNA Repair, Structural Biology, Fanconi Anemia Complementation Group D2 Protein, Ubiquitination, Humans, Ataxia Telangiectasia Mutated Proteins, DNA, Molecular Biology, Fanconi Anemia Complementation Group Proteins, Article, DNA Damage

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29732b28545880318807cd1c9a4253b6Test
https://doi.org/10.1038/s41594-022-00820-9Test

7

Deep learning enables the atomic structure determination of the Fanconi Anemia core complex from cryoEM

المؤلفون: Shabih Shakeel, Frank DiMaio, Daniel P. Farrell, David Baker, Anna Lauko, Ivan Anishchenko, Lori A. Passmore

المصدر: IUCrJ, Vol 7, Iss 5, Pp 881-892 (2020)
IUCrJ

مصطلحات موضوعية: Computer science, Protein subunit, fanconi anemia core complex, Interstrand crosslink, Computational biology, Biochemistry, Convolutional neural network, 03 medical and health sciences, 0302 clinical medicine, Fanconi anemia, medicine, Atomic model, General Materials Science, Protein secondary structure, 030304 developmental biology, Physics, 0303 health sciences, Crystallography, biology, business.industry, Deep learning, deep learning, General Chemistry, Condensed Matter Physics, medicine.disease, Research Papers, Ubiquitin ligase, cryoem, QD901-999, biology.protein, Protein folding, Artificial intelligence, distance predictions, business, Model building, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725d334761bc22a2f10a004f268a0802Test
http://scripts.iucr.org/cgi-bin/paper?S2052252520009306Test

8

Structure of the Fanconi anaemia monoubiquitin ligase complex

المؤلفون: Shabih Shakeel, Christopher J. Russo, Gianluca Degliesposti, Pablo Alcón, Eeson Rajendra, J.M. Skehel, Ketan J. Patel, Sarah L. Maslen, Carol V. Robinson, Chris H. Hill, Dror S. Chorev, Francis J. O’Reilly, Juri Rappsilber, Shaoda He, Sjors H.W. Scheres, Lori A. Passmore

المصدر: Shakeel, S, Rajendral, E, Alcón, P, O’Reilly, F J, Chorev, D S, Maslen, S, Degliesposti, G, Russo, C J, He, S, Hill, C H, Skehel, J M, Scheres, S H W, Patel, K J, Rappsilber, J, Robinson, C V & Passmore, L A 2019, ' Structure of the fanconi anaemia monoubiquitin ligase complex ', Nature, vol. 575, pp. 234-237 . https://doi.org/10.1038/s41586-019-1703-4Test
Nature

مصطلحات موضوعية: Models, Molecular, Protein subunit, Fanconi Anemia Complementation Group L Protein, medicine.disease_cause, Article, Mass Spectrometry, Ligases, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, FANCD2, Ring finger, medicine, Humans, Animals, FANCL, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, DNA ligase, Mutation, Multidisciplinary, biology, Fanconi Anemia Complementation Group D2 Protein, Cryoelectron Microscopy, Ubiquitination, Fanconi Anemia Complementation Group Proteins, Ubiquitin ligase, Cell biology, FANCB, Protein Subunits, Fanconi Anemia, medicine.anatomical_structure, chemistry, Multiprotein Complexes, biology.protein, Protein Multimerization, Chickens, 030217 neurology & neurosurgery