المؤلفون: Svarcbahs, Reinis, Julku, Ulrika H., Norrbacka, Susanna, Myöhänen, Timo T.

المصدر: Svarcbahs , R , Julku , U H , Norrbacka , S & Myöhänen , T T 2018 , ' Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo ' , Scientific Reports , vol. 8 , no. 1 , 1552 , pp. 1552 . https://doi.org/10.1038/s41598-018-19823-yTest

مصطلحات موضوعية: Animals, Autophagy, Behavior, Animal, Chromatography, High Pressure Liquid, Disease Models, Dopamine/analysis, Dopaminergic Neurons/pathology, Immunohistochemistry, Locomotion, Mice, Knockout, Parkinson Disease/physiopathology, Prolyl Oligopeptidases, Proteasome Endopeptidase Complex/metabolism, Serine Endopeptidases/deficiency, alpha-Synuclein/toxicity

العلاقة: https://cris.vtt.fi/en/publications/45511053-a3d2-4455-bd6c-da9ab31a1ff0Test

الإتاحة: https://doi.org/10.1038/s41598-018-19823-yTest
https://cris.vtt.fi/en/publications/45511053-a3d2-4455-bd6c-da9ab31a1ff0Test
http://www.scopus.com/inward/record.url?scp=85041045011&partnerID=8YFLogxKTest

المؤلفون: Keppner, A., Andreasen, D., Mérillat, A.M., Bapst, J., Ansermet, C., Wang, Q., Maillard, M., Malsure, S., Nobile, A., Hummler, E.

المصدر: Plos One, vol. 10, no. 8, pp. e0135224

مصطلحات موضوعية: Absorption, Physicochemical, Animals, Biological Transport, Cell Membrane/metabolism, Epithelial Sodium Channels/metabolism, Gene Knockout Techniques, Homeostasis, Membrane Proteins/deficiency, Membrane Proteins/genetics, Mice, Serine Endopeptidases/deficiency, Serine Endopeptidases/genetics, Sodium/metabolism

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/26309024; info:eu-repo/semantics/altIdentifier/eissn/1932-6203; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_0EC60EC08C029; https://serval.unil.ch/notice/serval:BIB_0EC60EC08C02Test; urn:issn:1932-6203; https://serval.unil.ch/resource/serval:BIB_0EC60EC08C02.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_0EC60EC08C029Test

الإتاحة: https://doi.org/10.1371/journal.pone.0135224Test
https://serval.unil.ch/notice/serval:BIB_0EC60EC08C02Test
https://serval.unil.ch/resource/serval:BIB_0EC60EC08C02.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_0EC60EC08C029Test

المؤلفون: Katsumi Maenaka, Shinsuke Toba, Hirofumi Sawa, Takao Sanaki, Michihito Sasaki, Akihiko Sato, Yasuko Orba, William W. Hall, Kentaro Uemura

المصدر: PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 1, p e1009233 (2021)

مصطلحات موضوعية: RNA viruses, Coronaviruses, Caco-2 Cells, Cell Lines, viruses, SARS-CoV-2/growth & development, Gene mutation, Amino Acid Sequence, medicine.disease_cause, Biochemistry, Serine Endopeptidases/deficiency, Chlorocebus aethiops, Macromolecular Structure Analysis, Biology (General), Sequence Alignment, Serial Passage, HEK293 Cells, Vero Cells, Pathology and laboratory medicine, Cell Line, Viral Tropism, Mutation, Antimicrobials, Serine Endopeptidases, Microbial Mutation, Drugs, Proteases, Medical microbiology, Antivirals, Transmembrane protein, Enzymes, Cell biology, Protein Cleavage, Spike Glycoprotein, Coronavirus, Viruses, SARS-CoV-2/genetics, Biological Cultures, SARS CoV 2, Pathogens, SARS-CoV-2/physiology, SARS-CoV-2/classification, Research Article, Protein Structure, SARS coronavirus, QH301-705.5, Immunology, Humans, Nucleotide Sequencing, Biology, Research and Analysis Methods, Cleavage (embryo), TMPRSS2, Microbiology, Virus, Viral entry, Microbial Control, Virology, Genetics, medicine, Animals, Molecular Biology Techniques, Sequencing Techniques, Molecular Biology, Tropism, Spike Glycoprotein, Coronavirus/genetics, Medicine and health sciences, Pharmacology, Biology and life sciences, SARS-CoV-2, Point mutation, Organisms, Viral pathogens, Proteins, RC581-607, Microbial pathogens, Vero cell, Enzymology, Tissue tropism, Parasitology, Immunologic diseases. Allergy, Serine Proteases

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52fc6925856570e50fca5bbdd2dd70d1Test
https://doi.org/10.1371/journal.ppat.1009233Test

المؤلفون: Reinis Svarcbahs, Timo T. Myöhänen, Ulrika Julku, Susanna Norrbacka

المساهمون: Faculty of Pharmacy, Division of Pharmacology and Pharmacotherapy, Regenerative pharmacology group, Drug Research Program, PREP in neurodegenerative disorders

المصدر: Svarcbahs, R, Julku, U H, Norrbacka, S & Myöhänen, T T 2018, ' Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo ', Scientific Reports, vol. 8, no. 1, 1552, pp. 1552 . https://doi.org/10.1038/s41598-018-19823-yTest
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-18 (2018)

مصطلحات موضوعية: 0301 basic medicine, Dopamine, lcsh:Medicine, HUMAN-BRAIN, Oligopeptidase, Pharmacology, chemistry.chemical_compound, Mice, 0302 clinical medicine, PARKINSONS-DISEASE, OXIDATIVE STRESS, lcsh:Science, PROTEASOME, Chromatography, High Pressure Liquid, Parkinson Disease/physiopathology, Mice, Knockout, Chromatography, Multidisciplinary, Behavior, Animal, Dopaminergic, Serine Endopeptidases, Parkinson Disease, Dopamine/analysis, alpha-Synuclein/toxicity, Immunohistochemistry, 3. Good health, 317 Pharmacy, High Pressure Liquid, Toxicity, alpha-Synuclein, ENDOPEPTIDASE, Prolyl Oligopeptidases, Locomotion, medicine.drug, Proteasome Endopeptidase Complex, Knockout, INHIBITION, CLEAVING ENZYME, Serine Endopeptidases/deficiency, Article, 03 medical and health sciences, In vivo, medicine, Autophagy, Animals, Alpha-synuclein, Behavior, Tyrosine hydroxylase, Animal, Dopaminergic Neurons, lcsh:R, Disease Models, Animal, Proteasome Endopeptidase Complex/metabolism, 030104 developmental biology, chemistry, Proteasome, Disease Models, Dopaminergic Neurons/pathology, lcsh:Q, SYSTEM, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::948368bd5bb442bafb3e91f5f9c7df49Test
https://cris.vtt.fi/en/publications/45511053-a3d2-4455-bd6c-da9ab31a1ff0Test

المؤلفون: Julie Bapst, Camille Ansermet, Anna Keppner, Antoine Nobile, Ditte Andreasen, Anne-Marie Mérillat, Sumedha Malsure, Edith Hummler, Marc Maillard, Qing Wang

المصدر: PLoS ONE, Vol 10, Iss 8, p e0135224 (2015)
PLoS One
PLoS ONE
Plos One, vol. 10, no. 8, pp. e0135224

مصطلحات موضوعية: Epithelial sodium channel, Proteases, medicine.medical_specialty, Sodium, Science, Absorption, Physicochemical, Animals, Biological Transport, Cell Membrane/metabolism, Epithelial Sodium Channels/metabolism, Gene Knockout Techniques, Homeostasis, Membrane Proteins/deficiency, Membrane Proteins/genetics, Mice, Serine Endopeptidases/deficiency, Serine Endopeptidases/genetics, Sodium/metabolism, chemistry.chemical_element, Biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, Internal medicine, medicine, Epithelial Sodium Channels, 030304 developmental biology, Serine protease, 0303 health sciences, Multidisciplinary, Aldosterone, urogenital system, Cell Membrane, Serine Endopeptidases, Membrane Proteins, respiratory system, Endocrinology, chemistry, 030220 oncology & carcinogenesis, Knockout mouse, biology.protein, Medicine, hormones, hormone substitutes, and hormone antagonists, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9631bd63ec79b62e0f63c8203a22a042Test
https://doaj.org/article/150db2d379c04a63818ede209b929fa0Test

المؤلفون: Cremer, C.M., Lübke, J.H.R., Palomero-Gallagher, N., Zilles, K.

المصدر: Brain structure & function 216, 201 - 218 (2011). doi:10.1007/s00429-011-0303-3

مصطلحات موضوعية: info:eu-repo/classification/ddc/610, Analysis of Variance, Animals, Autoradiography, Brain: anatomy & histology, Brain: metabolism, Brain Mapping: methods, Cell Adhesion Molecules, Neuronal: deficiency, Densitometry, Extracellular Matrix Proteins: deficiency, Image Processing, Computer-Assisted, Male, Mice, Neurologic Mutants: anatomy & histology, Neurologic Mutants: metabolism, Nerve Tissue Proteins: deficiency, Radioligand Assay, Receptors, Neurotransmitter: metabolism, Regression Analysis, Serine Endopeptidases: deficiency, Synaptic Transmission: physiology, Neuronal, Extracellular Matrix Proteins, Nerve Tissue Proteins, Neurotransmitter, Serine Endopeptidases, reelin protein

جغرافية الموضوع: DE

العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000293924300004; info:eu-repo/semantics/altIdentifier/pmid/pmid:21442415; info:eu-repo/semantics/altIdentifier/issn/1863-2653; https://juser.fz-juelich.de/record/14888Test; https://juser.fz-juelich.de/search?p=id:%22PreJuSER-14888%22Test

الإتاحة: https://doi.org/10.1007/s00429-011-0303-3Test
https://juser.fz-juelich.de/record/14888Test
https://juser.fz-juelich.de/search?p=id:%22PreJuSER-14888%22Test

المؤلفون: Guzman-Ayala, M., Ben-Haim, N., Beck, S., Constam, D.B.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 44, pp. 15656-15660

مصطلحات موضوعية: Animals, Cell Differentiation, Female, Fibroblast Growth Factor 4, Fibroblast Growth Factors/genetics, Furin/deficiency, Furin/genetics, Gene Expression/drug effects, Mice, Inbred C57BL, Knockout, Models, Biological, Nodal Protein, Pregnancy, Proprotein Convertases, Protein Processing, Post-Translational, Proto-Oncogene Proteins/genetics, Recombinant Proteins/pharmacology, Serine Endopeptidases/deficiency, Serine Endopeptidases/genetics, Stem Cells/cytology, Stem Cells/metabolism, Tissue Culture Techniques, Transforming Growth Factor beta/genetics, Transforming Growth Factor beta/metabolism, Trophoblasts/cytology, Trophoblasts/metabolism

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/15505202; info:eu-repo/semantics/altIdentifier/pissn/0027-8424; https://serval.unil.ch/notice/serval:BIB_31437Test

الإتاحة: https://doi.org/10.1073/pnas.0405429101Test
https://serval.unil.ch/notice/serval:BIB_31437Test

المؤلفون: Sasaki, Michihito, Uemura, Kentaro, Sato, Akihiko, Toba, Shinsuke, Sanaki, Takao, Maenaka, Katsumi, Hall, William W, Orba, Yasuko, Sawa, Hirofumi

مصطلحات موضوعية: Amino Acid Sequence, Animals, Caco-2 Cells, Cell Line, Chlorocebus aethiops, HEK293 Cells, Humans, Mutation, SARS-CoV-2/classification, SARS-CoV-2/genetics, SARS-CoV-2/growth & development, SARS-CoV-2/physiology, Sequence Alignment, Serial Passage, Serine Endopeptidases/deficiency, Spike Glycoprotein, Coronavirus/genetics, Vero Cells, Viral Tropism

الوقت: 490

العلاقة: http://hdl.handle.net/2115/80558Test; PLoS pathogens, 17(1): e1009233; http://dx.doi.org/10.1371/journal.ppat.1009233Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1009233Test
http://hdl.handle.net/2115/80558Test

المؤلفون: Monod, M., Paris, S., Sarfati, J., Jaton-Ogay, K., Ave, P., Latge, J. P.

المصدر: FEMS Microbiology Letters, vol. 106, no. 1, pp. 39-46

مصطلحات موضوعية: Animals Aspergillus fumigatus/enzymology/*pathogenicity Chromosome Mapping Cloning, Molecular Collagen/metabolism Drug Resistance, Microbial Elastin/metabolism Electrophoresis, Polyacrylamide Gel Gene Deletion Genes, Fungal/physiology Hygromycin B Lung/pathology Male Mice Mice, Inbred Strains Polymorphism, Restriction Fragment Length Protein Biosynthesis Serine Endopeptidases/*deficiency/genetics Transformation, Genetic Virulence/physiology

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/8095038; info:eu-repo/semantics/altIdentifier/pissn/0378-1097; https://serval.unil.ch/notice/serval:BIB_FF6456667F3FTest

الإتاحة: https://serval.unil.ch/notice/serval:BIB_FF6456667F3FTest

مصطلحات الفهرس: Amino Acid Sequence, Animals, Caco-2 Cells, Cell Line, Chlorocebus aethiops, HEK293 Cells, Humans, Mutation, SARS-CoV-2/classification, SARS-CoV-2/genetics, SARS-CoV-2/growth & development, SARS-CoV-2/physiology, Sequence Alignment, Serial Passage, Serine Endopeptidases/deficiency, Spike Glycoprotein, Coronavirus/genetics, Vero Cells, Viral Tropism, 490, article

URL: http://hdl.handle.net/2115/80558Test