المؤلفون: Spears, Meghan, Lee, Namgyu, Hwang, Sunyoung, Park, Sung, Carlisle, Anne, Li, Rui, Doshi, Mihir, Armando, Aaron, Gao, Jenny, Simin, Karl, Zhu, Lihua, Greer, Paul, Quehenberger, Oswald, Torres, Eduardo, Kim, Dohoon

المصدر: Cell Reports. 40(13)

مصطلحات موضوعية: CP: Cancer, CP: Metabolism, cancer metabolism, cancer therapy, endoplasmic reticulum, ketodihydrosphingosine reductase, serine palmitoyltransferase, Lipogenesis, Neoplasms, Oxidoreductases, Serine, Serine C-Palmitoyltransferase, Sphingolipids, Sphingosine

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/29v8t3q2Test

المؤلفون: Piccolo, Brian D, Graham, James L, Kang, Ping, Randolph, Christopher E, Shankar, Kartik, Yeruva, Laxmi, Fox, Renee, Robeson, Michael S, Moody, Becky, LeRoith, Tanya, Stanhope, Kimber L, Adams, Sean H, Havel, Peter J

المصدر: Physiological Reports. 9(22)

مصطلحات موضوعية: Medical Physiology, Biomedical and Clinical Sciences, Digestive Diseases, Human Genome, Diabetes, Colo-Rectal Cancer, Cancer, Genetics, Autoimmune Disease, Aetiology, 2.1 Biological and endogenous factors, Metabolic and endocrine, Akkermansia, Amino Acid Transport Systems, Neutral, Animals, Clostridiales, Colon, Diabetes Mellitus, Type 2, Disease Progression, Dysbiosis, Gastrointestinal Microbiome, Gene Expression Profiling, Ileum, Intestinal Mucosa, Potassium Channels, RNA, Ribosomal, 16S, Rats, Serine C-Palmitoyltransferase, Sphingomyelin Phosphodiesterase, Veillonellaceae, crypt, diabetes, microbiome, RNA-seq, UCD-T2DM rat, villi, Physiology, Clinical Sciences, Medical physiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8kw2p95qTest

المؤلفون: Muthusamy, Thangaselvam, Cordes, Thekla, Handzlik, Michal K, You, Le, Lim, Esther W, Gengatharan, Jivani, Pinto, Antonio FM, Badur, Mehmet G, Kolar, Matthew J, Wallace, Martina, Saghatelian, Alan, Metallo, Christian M

المصدر: Nature. 586(7831)

مصطلحات موضوعية: Nutrition, Aetiology, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, 2.1 Biological and endogenous factors, Cancer, Alanine, Animals, Cell Adhesion, Cell Division, Diet, Female, Glycine, HCT116 Cells, Humans, Membrane Lipids, Mice, Mitochondria, Neoplasms, Phosphoglycerate Dehydrogenase, Pyruvic Acid, Serine, Serine C-Palmitoyltransferase, Spheroids, Cellular, Sphingolipids, Stress, Physiological, Xenograft Model Antitumor Assays, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3rs223c0Test

المؤلفون: Chen, Tzu-Chieh, Lee, Rebecca A, Tsai, Sam L, Kanamaluru, Deepthi, Gray, Nora E, Yiv, Nicholas, Cheang, Rachel T, Tan, Jenna H, Lee, Justin Y, Fitch, Mark D, Hellerstein, Marc K, Wang, Jen-Chywan

المصدر: Journal of Biological Chemistry. 294(23)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Genetics, Liver Disease, Digestive Diseases, Chronic Liver Disease and Cirrhosis, Aetiology, 2.1 Biological and endogenous factors, Angiopoietin-Like Protein 4, Animals, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Ceramides, Dexamethasone, Fatty Acid Synthase, Type I, Fatty Acids, Monounsaturated, Fatty Liver, Hypertriglyceridemia, Lipogenesis, Liver, Male, Mice, Mice, Knockout, Protein Kinase C, Protein Phosphatase 2, RNA Interference, RNA, Small Interfering, Serine C-Palmitoyltransferase, Triglycerides, liver, glucocorticoid, ceramide, triglyceride, metabolic syndrome, steroid hormone, dyslipidemia, lipogenesis, fatty liver disease, hepatosteatosis, hypertriglyceridemia, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8f57n61mTest

المؤلفون: Lallement, Justine, Raho, Ilyès, Merlen, Grégory, Rainteau, Dominique, Croyal, Mikael, Schiffano, Melody, Kassis, Nadim, Doignon, Isabelle, Soty, Maud, Lachkar, Floriane, Krempf, Michel, van Hul, Matthias, Cani, Patrice D., Foufelle, Fabienne, Amouyal, Chloé, Le Stunff, Hervé, Magnan, Christophe, Tordjmann, Thierry, Cruciani-Guglielmacci, Céline

المساهمون: Unité de Biologie Fonctionnelle et Adaptative (BFA (UMR_8251 / U1133)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Physiopathologie et traitement des maladies du foie, Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Microbiote, intestin et inflammation CRSA, Centre de Recherche Saint-Antoine (CRSA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), PHU 2 - Institut du Thorax et du Sytème Nerveux CHU Nantes (ITSN), Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Physiopathologie des Adaptations Nutritionnelles (PhAN), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Nutrition et cerveau (U1213, U855), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Clinique Bretéché, Groupe Elsan, Nantes, Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique de Louvain = Catholic University of Louvain (UCL), Institut des Neurosciences Paris-Saclay (NeuroPSI), Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), ANR-17-EURE-0013,GENE,Génétique et Epigénétique Nouvelle Ecole(2017), ANR-18-IDEX-0001,Université de Paris,Université de Paris(2018)

المصدر: ISSN: 1388-1981 ; Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids ; https://cnrs.hal.science/hal-04282229Test ; Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2023, 1868 (8), pp.1-13. ⟨10.1016/j.bbalip.2023.159333⟩.

مصطلحات موضوعية: Bile acids, Ceramides, Fibrosis, Gluconeogenesis, Liver, Sphingomyelinase, MESH: Animals, MESH: Mice, MESH: Serine, MESH: Serine C-Palmitoyltransferase, MESH: Sphingolipids, MESH: Sphingomyelins, MESH: Bile Acids and Salts, MESH: Ceramides, MESH: Diabetes Mellitus, Type 2, MESH: Glucose, MESH: Homeostasis, MESH: Liver, [SDV]Life Sciences [q-bio]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37224999; hal-04282229; https://cnrs.hal.science/hal-04282229Test; https://cnrs.hal.science/hal-04282229/documentTest; https://cnrs.hal.science/hal-04282229/file/2023_Lallement_BBA.pdfTest; PUBMED: 37224999; WOS: 001012679700001

الإتاحة: https://doi.org/10.1016/j.bbalip.2023.159333Test
https://cnrs.hal.science/hal-04282229Test
https://cnrs.hal.science/hal-04282229/documentTest
https://cnrs.hal.science/hal-04282229/file/2023_Lallement_BBA.pdfTest

المؤلفون: Shahin, Mohamed H, Gong, Yan, Frye, Reginald F, Rotroff, Daniel M, Beitelshees, Amber L, Baillie, Rebecca A, Chapman, Arlene B, Gums, John G, Turner, Stephen T, Boerwinkle, Eric, Motsinger‐Reif, Alison, Fiehn, Oliver, Cooper‐DeHoff, Rhonda M, Han, Xianlin, Kaddurah‐Daouk, Rima, Johnson, Julie A

المصدر: Journal of the American Heart Association. 7(1)

مصطلحات موضوعية: Human Genome, Genetics, Hypertension, Biotechnology, 2.1 Biological and endogenous factors, Aetiology, Cardiovascular, Adult, Blood Pressure, Female, Genomics, Humans, Hydrochlorothiazide, Lipid Metabolism, Male, Metabolic Networks and Pathways, Metabolomics, Middle Aged, Nitriles, Pharmacogenetics, Prognosis, Serine C-Palmitoyltransferase, Siloxanes, Sodium Chloride Symporter Inhibitors, Sphingolipids, Treatment Outcome, blood pressure, lipid metabolites, metabolomics, pharmacogenetics, thiazide diuretics, Cardiorespiratory Medicine and Haematology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/0z191365Test

المؤلفون: Cordes, Thekla, Kuna, Ramya S, McGregor, Grace H, Khare, Sanika V, Gengatharan, Jivani, Muthusamy, Thangaselvam, Metallo, Christian M

المصدر: Journal of lipid research 63 (2022) 10, 100281. - https://doi.org/10.1016/j.jlr.2022.100281Test -- J Lipid Res -- 0022-2275 -- 1539-7262

مصطلحات موضوعية: Article, ddc:572, Veröffentlichung der TU Braunschweig, Publikationsfonds der TU Braunschweig, Cell Membrane, Neoplasms, Ceramides, Agar, Sphingolipids, Alanine, Serine, Endocytosis, Serine C-Palmitoyltransferase, Metabolic Networks and Pathways, Metabolism, Rab5, soft agar, Serine Palmitoyltransferase, Mitochondrial Stress, 1-Deoxy(dihydro)ceramide, 1-Deoxysphingolipid Accumulation, Spt Promiscuity

وصف الملف: 13 Seiten

العلاقة: https://doi.org/10.1016/j.jlr.2022.100281Test; https://nbn-resolving.org/urn:nbn:de:gbv:084-2022121513286Test; https://leopard.tu-braunschweig.de/receive/dbbs_mods_00071791Test; https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00050419/Cordes_PIIS0022227522001146.pdfTest; http://publikationsserver.tu-braunschweig.de/get/71791Test; http://www.jlr.org/article/S0022227522001146/pdfTest

الإتاحة: https://doi.org/10.1016/j.jlr.2022.100281Test
https://nbn-resolving.org/urn:nbn:de:gbv:084-2022121513286Test
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00071791Test
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00050419/Cordes_PIIS0022227522001146.pdfTest
http://publikationsserver.tu-braunschweig.de/get/71791Test
http://www.jlr.org/article/S0022227522001146/pdfTest

المؤلفون: Realini, Natalia, Palese, Francesca, Pizzirani, Daniela, Pontis, Silvia, Basit, Abdul, Bach, Anders, Ganesan, Anand, Piomelli, Daniele

المصدر: Journal of Biological Chemistry. 291(5)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biological Sciences, Cancer, Acid Ceramidase, Cell Line, Tumor, Cell Proliferation, Cell Survival, Ceramides, Down-Regulation, Enzyme Inhibitors, Fibroblasts, Gene Expression Regulation, Neoplastic, HCT116 Cells, Hep G2 Cells, Humans, Inhibitory Concentration 50, Keratinocytes, Lipids, Lysophospholipids, MCF-7 Cells, Melanocytes, Melanoma, Microscopy, Confocal, Microscopy, Fluorescence, Oxidoreductases, RNA, Small Interfering, Serine C-Palmitoyltransferase, Signal Transduction, Skin Neoplasms, Sphingolipids, Sphingosine, Uracil, acid ceramidase, cancer biology, ceramide, enzyme inhibitor, melanoma, sphingolipid, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/2w355221Test

المؤلفون: Samokhvalov, Victor, Zlobine, Igor, Jamieson, Kristi L, Jurasz, Paul, Chen, Christopher, Lee, Kin Sing Stephen, Hammock, Bruce D, Seubert, John M

المصدر: Toxicology Letters. 232(1)

مصطلحات موضوعية: Pharmacology and Pharmaceutical Sciences, Biomedical and Clinical Sciences, Complementary and Integrative Health, Dietary Supplements, Cancer, Activation, Metabolic, Animals, Apoptosis, Benzamides, Cardiotoxicity, Cell Line, Cell Survival, Ceramides, Cytochrome P-450 Enzyme System, Docosahexaenoic Acids, Energy Metabolism, Enzyme Inhibitors, Fatty Acids, Monounsaturated, Ligands, Myocytes, Cardiac, Oxidation-Reduction, PPAR delta, Rats, Serine C-Palmitoyltransferase, Signal Transduction, Sulfones, Time Factors, Docosahexaenoic acid, Epoxydocosapentaenoic acids, H9c2?cells, Ceramide, H9c2 cells, PPARδ, Environmental Science and Management, Toxicology, Pharmacology and pharmaceutical sciences, Pollution and contamination

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7cw569mbTest
https://escholarship.org/content/qt7cw569mb/qt7cw569mb.pdfTest

المؤلفون: Johnson J. O., Chia R., Miller D. E., Li R., Kumaran R., Abramzon Y., Alahmady N., Renton A. E., Topp S. D., Gibbs J. R., Cookson M. R., Sabir M. S., Dalgard C. L., Troakes C., Jones A. R., Shatunov A., Iacoangeli A., Al Khleifat A., Ticozzi N., Silani V., Gellera C., Blair I. P., Dobson-Stone C., Kwok J. B., Bonkowski E. S., Palvadeau R., Tienari P. J., Morrison K. E., Shaw P. J., Al-Chalabi A., Brown R. H., Calvo A., Mora G., Al-Saif H., Gotkine M., Leigh F., Chang I. J., Perlman S. J., Glass I., Scott A. I., Shaw C. E., Basak A. N., Landers J. E., Chio A., Crawford T. O., Smith B. N., Traynor B. J., Fallini C., Gkazi A. S., Scotter E. L., Kenna K. P., Keagle P., Tiloca C., Vance C., Colombrita C., King A., Pensato V., Castellotti B., Baas F., Ten Asbroek A. L. M. A., McKenna-Yasek D., McLaughlin R. L., Polak M., Asress S., Esteban-Perez J., Stevic Z., D'Alfonso S., Mazzini L., Comi G. P., Del Bo R., Ceroni M., Gagliardi S., Querin G., Bertolin C., Van Rheenen W., Rademakers R., Van Blitterswijk M., Lauria G., Duga S., Corti S., Cereda C., Corrado L., Soraru G., Williams K. L., Nicholson G. A., Leblond-Manry C., Rouleau G. A., Hardiman O., Veldink J. H., Van Den Berg L. H., Pall H., Turner M. R., Talbot K., Taroni F., Garcia-Redondo A., Wu Z., Glass J. D., Ratti A., Adeleye A., Soltis A. R., Alba C., Viollet C., Bacikova D., Hupalo D. N., Sukumar G., Pollard H. B., Wilkerson M. D., Martinez E. M., Ahmed S., Arepalli S., Baloh R. H., Bowser R., Brady C. B., Brice A., Broach J., Campbell R. H., Camu W., Cooper-Knock J., Ding J., Drepper C., Drory V. E., Dunckley T. L., Eicher J. D., England B. K., Faghri F., Feldman E., Floeter M. K., Fratta P., Geiger J. T., Gerhard G., Gibson S. B., Hardy J., Harms M. B., Heiman-Patterson T. D., Hernandez D. G., Jansson L., Kirby J., Kowall N. W., Laaksovirta H., Landeck N., Landi F., Le Ber I., Lumbroso S., Macgowan D. J. L., Maragakis N. J., Mouzat K., Murphy N. A., Myllykangas L., Nalls M. A., Orrell R. W., Ostrow L. W., Pamphlett R., Pickering-Brown S., Pioro E. P., Pletnikova O., Pliner H. A., Pulst S. M., Ravits J. M., Rivera A., Robberecht W., Rogaeva E., Rollinson S., Rothstein J. D., Scholz S. W., Sendtner M., Sidle K. C., Simmons Z., Singleton A. B., Smith N., Stone D. J., Troncoso J. C., Valori M., Van Damme P., Van Deerlin V. M., Van Den Bosch L., Zinman L., Angelocola S. M., Ausiello F. P., Barberis M., Bartolomei I., Battistini S., Bersano E., Bisogni G., Borghero G., Brunetti M., Cabona C., Canale F., Canosa A., Cantisani T. A., Capasso M., Caponnetto C., Cardinali P., Carrera P., Casale F., Colletti T., Conforti F. L., Conte A., Conti E., Corbo M., Cuccu S., Dalla Bella E., D'Errico E., Demarco G., Dubbioso R., Ferrarese C., Ferraro P. M., Filippi M., Fini N., Floris G., Fuda G., Gallone S., Gianferrari G., Giannini F., Grassano M., Greco L., Iazzolino B., Introna A., La Bella V., Lattante S., Liguori R., Logroscino G., Logullo F. O., Lunetta C., Mandich P., Mandrioli J., Manera U., Manganelli F., Marangi G., Marinou K., Marrosu M. G., Martinelli I., Messina S., Moglia C., Mosca L., Murru M. R., Origone P., Passaniti C., Petrelli C., Petrucci A., Pozzi S., Pugliatti M., Quattrini A., Ricci C., Riolo G., Riva N., Russo M., Sabatelli M., Salamone P., Salivetto M., Salvi F., Santarelli M., Sbaiz L., Sideri R., Simone I., Simonini C., Spataro R., Tanel R., Tedeschi G., Ticca A., Torriello A., Tranquilli S., Tremolizzo L., Trojsi F., Vasta R., Vacchiano V., Vita G., Volanti P., Zollino M., Zucchi E.

المساهمون: Johnson, J. O., Chia, R., Miller, D. E., Li, R., Kumaran, R., Abramzon, Y., Alahmady, N., Renton, A. E., Topp, S. D., Gibbs, J. R., Cookson, M. R., Sabir, M. S., Dalgard, C. L., Troakes, C., Jones, A. R., Shatunov, A., Iacoangeli, A., Al Khleifat, A., Ticozzi, N., Silani, V., Gellera, C., Blair, I. P., Dobson-Stone, C., Kwok, J. B., Bonkowski, E. S., Palvadeau, R., Tienari, P. J., Morrison, K. E., Shaw, P. J., Al-Chalabi, A., Brown, R. H., Calvo, A., Mora, G., Al-Saif, H., Gotkine, M., Leigh, F., Chang, I. J., Perlman, S. J., Glass, I., Scott, A. I., Shaw, C. E., Basak, A. N., Landers, J. E., Chio, A., Crawford, T. O., Smith, B. N., Traynor, B. J., Fallini, C., Gkazi, A. S., Scotter, E. L., Kenna, K. P., Keagle, P., Tiloca, C., Vance, C., Colombrita, C., King, A., Pensato, V., Castellotti, B., Baas, F., Ten Asbroek, A. L. M. A., McKenna-Yasek, D., Mclaughlin, R. L., Polak, M., Asress, S., Esteban-Perez, J., Stevic, Z., D'Alfonso, S., Mazzini, L., Comi, G. P., Del Bo, R., Ceroni, M., Gagliardi, S., Querin, G., Bertolin, C., Van Rheenen, W., Rademakers, R., Van Blitterswijk, M., Lauria, G., Duga, S., Corti, S., Cereda, C., Corrado, L., Soraru, G., Williams, K. L., Nicholson, G. A., Leblond-Manry, C., Rouleau, G. A., Hardiman, O., Veldink, J. H., Van Den Berg, L. H., Pall, H., Turner, M. R.

مصطلحات موضوعية: Adolescent, Adult, Amyotrophic Lateral Sclerosi, Child, Preschool, Female, Genetic Predisposition to Disease, Human, Mutation, Serine C-Palmitoyltransferase, Whole Exome Sequencing, Young Adult

وصف الملف: STAMPA

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34459874; info:eu-repo/semantics/altIdentifier/wos/WOS:000692566100005; volume:78; issue:10; firstpage:1236; lastpage:1248; numberofpages:13; journal:JAMA NEUROLOGY; http://hdl.handle.net/11365/1181203Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85114289450; https://jamanetwork.com/journals/jamaneurology/fullarticle/2783665Test; https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8406220Test/

الإتاحة: https://doi.org/10.1001/jamaneurol.2021.2598Test
http://hdl.handle.net/11365/1181203Test
https://jamanetwork.com/journals/jamaneurology/fullarticle/2783665Test
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8406220Test/