-
1دورية أكاديمية
المؤلفون: Michal R. Tomaszewski, Xiangjun Meng, Hyking D. Haley, Charles M. Harrell, Terrence P. Mcdonald, Corin O. Miller, Sean M. Smith
المصدر: Journal of Lipid Research, Vol 64, Iss 8, Pp 100408- (2023)
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227523000810Test; https://doaj.org/toc/0022-2275Test
-
2دورية أكاديمية
المؤلفون: Lisa N. Scott, Sean M. Smith, John S. Gunn, Marek Petrik, Mark J. Ducey, Thomas S. Buchholz, Ethan P. Belair
المصدر: Frontiers in Forests and Global Change, Vol 6 (2023)
مصطلحات موضوعية: carbon, lasso, eastern spruce budworm, decision-support, discounting, Forestry, SD1-669.5, Environmental sciences, GE1-350
وصف الملف: electronic resource
العلاقة: https://www.frontiersin.org/articles/10.3389/ffgc.2023.1062176/fullTest; https://doaj.org/toc/2624-893XTest
-
3دورية أكاديمية
المؤلفون: Nanyan Rena Zhang, Nathan G. Hatcher, Kim Ekroos, Komal Kedia, Monika Kandebo, Jacob N. Marcus, Sean M. Smith, Kevin P. Bateman, Daniel S. Spellman
المصدر: Journal of Lipid Research, Vol 63, Iss 6, Pp 100218- (2022)
مصطلحات موضوعية: quantitative lipidomics, targeted lipidomics, hydrophilic interaction chromatography (HILIC), normal phase liquid chromatography (NPLC), triple quadrupole mass spectrometry, scheduled MRM, Biochemistry, QD415-436
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S0022227522000517Test; https://doaj.org/toc/0022-2275Test
-
4دورية أكاديمية
المؤلفون: Nicole K. Polinski, Terina N. Martinez, Sylvie Ramboz, Michael Sasner, Mark Herberth, Robert Switzer, Syed O. Ahmad, Lee J. Pelligrino, Sean W. Clark, Jacob N. Marcus, Sean M. Smith, Kuldip D. Dave, Mark A. Frasier
المصدر: Disease Models & Mechanisms, Vol 15, Iss 6 (2022)
مصطلحات موضوعية: gcase, alpha-synuclein, parkinson's disease, Medicine, Pathology, RB1-214
وصف الملف: electronic resource
العلاقة: http://dmm.biologists.org/content/15/6/dmm049192Test; https://doaj.org/toc/1754-8403Test; https://doaj.org/toc/1754-8411Test
-
5دورية أكاديمية
المؤلفون: Mali Cosden, Sarah Jinn, Lihang Yao, Cheryl A. Gretzula, Monika Kandebo, Dawn Toolan, Nathan G. Hatcher, Lei Ma, Wei Lemaire, Gregory C. Adam, Christine Burlein, Christina Minnick, Rose Flick, Marla L. Watt, James Mulhearn, Mark Fraley, Robert E. Drolet, Jacob N. Marcus, Sean M. Smith
المصدر: Neurobiology of Disease, Vol 159, Iss , Pp 105507- (2021)
مصطلحات موضوعية: Glucocerebrosidase, Glucosylceramide synthase inhibitor, Glycosphingolipids, Parkinson's disease, Lysosomal biology, Preformed fibril model, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S0969996121002564Test; https://doaj.org/toc/1095-953XTest
-
6دورية أكاديمية
المؤلفون: Andrew Goodspeed, Nicolas Kostman, Trenton E. Kriete, Joel W. Longtine, Sean M. Smith, Peregrin Marshall, Wesley Williams, Cheryl Clark, Weston W. Blakeslee
المصدر: Annals of General Psychiatry, Vol 18, Iss 1, Pp 1-11 (2019)
مصطلحات موضوعية: Focus group, Pharmacogenetics, Pharmacogenomics, Clinical decision support, Psychiatry, Mental and behavioral health, RC435-571
وصف الملف: electronic resource
العلاقة: http://link.springer.com/article/10.1186/s12991-019-0237-3Test; https://doaj.org/toc/1744-859XTest
-
7دورية أكاديمية
المؤلفون: Emily M. Rocha, Briana R. De Miranda, Sandra Castro, Robert Drolet, Nathan G. Hatcher, Lihang Yao, Sean M. Smith, Matthew T. Keeney, Roberto Di Maio, Julia Kofler, Teresa G. Hastings, J. Timothy Greenamyre
المصدر: Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
العلاقة: http://www.sciencedirect.com/science/article/pii/S0969996119303018Test; https://doaj.org/toc/1095-953XTest
-
8دورية أكاديميةFluorinated Isoindolinone-Based Glucosylceramide Synthase Inhibitors with Low Human Dose Projections
المؤلفون: H. Marie Loughran, Kathy M. Schirripa, Anthony J. Roecker, Michael J. Breslin, Ling Tong, Kerry L. Fillgrove, Yuhsin Kuo, Kelly Bleasby, Hannah Collier, Michael D. Altman, Melissa C. Ford, Justin A. Newman, Robert E. Drolet, Mali Cosden, Sarah Jinn, Rosemarie B. Flick, Xiaomei Liu, Christina Minnick, Marla L. Watt, Wei Lemaire, Christine Burlein, Gregory C. Adam, Lauren A. Austin, Jacob N. Marcus, Sean M. Smith, Mark E. Fraley
مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Pharmacology, Biotechnology, Marine Biology, Cancer, Hematology, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, pd ), particularly, lower human dose, low human doses, favorable pxr selectivity, v <, therapeutic strategy, strategy involved, strategies enabled, stage optimization, screening funnel, parkinson ’, orally bioavailable, lysosomal impairment, greater potential, glycosphingolipid accumulation, glucosylceramide synthase, fluorine substitution
الإتاحة: https://doi.org/10.1021/acsmedchemlett.3c00436.s001Test
https://figshare.com/articles/journal_contribution/Fluorinated_Isoindolinone-Based_Glucosylceramide_Synthase_Inhibitors_with_Low_Human_Dose_Projections/24887064Test -
9دورية أكاديمية
المؤلفون: Mark E. Layton (1443547), Jeffrey C. Kern (2399026), Timothy J. Hartingh (1503232), William D. Shipe (1514749), Izzat Raheem (14370322), Monika Kandebo (10947802), Robert P. Hayes (9220508), Sarah Huszar (14370325), Donnie Eddins (14370328), Bennett Ma (14370331), Joy Fuerst (5175641), Gordon K. Wollenberg (14370334), Jing Li (10611), Jeff Fritzen (7491188), Georgia B. McGaughey (1270989), Jason M. Uslaner (1514734), Sean M. Smith (1514728), Paul J. Coleman (1834798), Christopher D. Cox (1514737)
مصطلحات موضوعية: Biochemistry, Cell Biology, Neuroscience, Pharmacology, Biotechnology, Developmental Biology, Mental Health, Hematology, Chemical Sciences not elsewhere classified, rational design led, potentially novel means, normalize dysfunctional activity, selective pde10a inhibitor, pde10a inhibition represents, developing pde10a inhibitors, dysfunctional striatal activity, isomeric pyrimidine series, 18 b, striatal signaling, schizophrenia pde10a, target activities, physicochemical properties, liabilities seen, important regulator, highly potent, fragment hit, early optimization, earlier compounds
-
10
المؤلفون: Anthony J. Roecker, Kathy M. Schirripa, H. Marie Loughran, Ling Tong, Tao Liang, Kerry L. Fillgrove, Yuhsin Kuo, Kelly Bleasby, Hannah Collier, Michael D. Altman, Melissa C. Ford, Robert E. Drolet, Mali Cosden, Sarah Jinn, Nathan G. Hatcher, Lihang Yao, Monika Kandebo, Joshua D. Vardigan, Rosemarie B. Flick, Xiaomei Liu, Christina Minnick, Laura A. Price, Marla L. Watt, Wei Lemaire, Christine Burlein, Gregory C. Adam, Lauren A. Austin, Jacob N. Marcus, Sean M. Smith, Mark E. Fraley
المصدر: ACS Medicinal Chemistry Letters. 14:146-155
مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::69a75f2713f77a436a3c71e753c7d659Test
https://doi.org/10.1021/acsmedchemlett.2c00441Test