المؤلفون: Abdeen, Sanofar, Salim, Nilshad, Mammadova, Najiba, Summers, Corey M., Frankson, Rochelle, Ambrose, Andrew J., Anderson, Gregory G., Schultz, Peter G., Horwich, Arthur L., Chapman, Eli, Johnson, Steven M.

مرشدي الرسالة: The University of Arizona, College of Pharmacy, Department of Pharmacology and Toxicology

مصطلحات موضوعية: GroEL, GroES, HSP60, HSP10, Molecular chaperone, Chaperonin, Proteostasis, Small molecule inhibitors, ESKAPE pathogens, Antibiotics

العلاقة: http://linkinghub.elsevier.com/retrieve/pii/S0960894X16304772Test

الإتاحة: http://hdl.handle.net/10150/618724Test
http://arizona.openrepository.com/arizona/handle/10150/618724Test

المؤلفون: Elshan, N. G. R. Dayan, Wolff, Karen C., Riva, Laura, Woods, Ashley K., Grabovyi, Gennadii, Wilson, Katy, Pedroarena, James, Ghorai, Sourav, Nazarian, Armen, Weiss, Frank, Liu, Yuyin, Mazumdar, Wrickban, Song, Lirui, Okwor, Neechi, Malvin, Jacqueline, Liu, Dongdong, Bakowski, Malina A., Beutler, Nathan, Kirkpatrick, Melanie G., Gebara-Lamb, Amal, Huang, Edward, Nguyen-Tran, Vân T. B., Chi, Victor, Li, Shuangwei, Rogers, Thomas F., McNamara, Case W., Gupta, Anil Kumar, Rahimi, Alireza, Chen, Jian Jeffrey, Joseph, Sean B., Schultz, Peter G., Chatterjee, Arnab K.

المساهمون: Bill and Melinda Gates Foundation

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 12, page 10508-10509 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.4c01269Test

المؤلفون: Dayan Elshan, N. G. R., Wolff, Karen C., Riva, Laura, Woods, Ashley K., Grabovyi, Gennadii, Wilson, Katy, Pedroarena, James, Ghorai, Sourav, Nazarian, Armen, Weiss, Frank, Liu, Yuyin, Mazumdar, Wrickban, Song, Lirui, Okwor, Neechi, Malvin, Jacqueline, Bakowski, Malina A., Beutler, Nathan, Kirkpatrick, Melanie G., Gebara-Lamb, Amal, Huang, Edward, Nguyen-Tran, Vân T. B., Chi, Victor, Li, Shuangwei, Rogers, Thomas F., McNamara, Case W., Gupta, Anil Kumar, Rahimi, Alireza, Chen, Jian Jeffrey, Joseph, Sean B., Schultz, Peter G., Chatterjee, Arnab K.

المساهمون: Bill and Melinda Gates Foundation

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 4, page 2369-2378 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c01938Test

المؤلفون: Lee, Sung Chang, Ma, Jennifer SY, Kim, Min Soo, Laborda, Eduardo, Choi, Sei-Hyun, Hampton, Eric N, Yun, Hwayoung, Nunez, Vanessa, Muldong, Michelle T, Wu, Christina N, Ma, Wenxue, Kulidjian, Anna A, Kane, Christopher J, Klyushnichenko, Vadim, Woods, Ashley K, Joseph, Sean B, Petrassi, Mike, Wisler, John, Li, Jing, Jamieson, Christina AM, Schultz, Peter G, Kim, Chan Hyuk, Young, Travis S

المصدر: Science Advances. 7(33)

مصطلحات موضوعية: Cancer, Clinical Research, Urologic Diseases, Prevention, Biotechnology, Prostate Cancer, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Animals, Antibodies, Bispecific, CD3 Complex, Cell Line, Tumor, Clinical Trials as Topic, Humans, Ligands, Male, Mice, Prostatic Neoplasms, Castration-Resistant, T-Lymphocytes

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8zv4t8s4Test

المؤلفون: Bakowski, Malina A, Beutler, Nathan, Wolff, Karen C, Kirkpatrick, Melanie G, Chen, Emily, Nguyen, Tu-Trinh H, Riva, Laura, Shaabani, Namir, Parren, Mara, Ricketts, James, Gupta, Anil K, Pan, Kastin, Kuo, Peiting, Fuller, MacKenzie, Garcia, Elijah, Teijaro, John R, Yang, Linlin, Sahoo, Debashis, Chi, Victor, Huang, Edward, Vargas, Natalia, Roberts, Amanda J, Das, Soumita, Ghosh, Pradipta, Woods, Ashley K, Joseph, Sean B, Hull, Mitchell V, Schultz, Peter G, Burton, Dennis R, Chatterjee, Arnab K, McNamara, Case W, Rogers, Thomas F

المصدر: Nature communications. 12(1)

مصطلحات موضوعية: Cell Line, Hela Cells, Animals, Humans, Mesocricetus, Hydroxylamines, Nelfinavir, Cytidine, Antiviral Agents, Drug Evaluation, Preclinical, Virus Replication, Drug Discovery, High-Throughput Screening Assays, Drug Repositioning, Pandemics, Databases, Pharmaceutical, COVID-19, SARS-CoV-2, HeLa Cells

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/77f9r1t7Test

المؤلفون: Koh, Minseob, Ahmad, Insha, Ko, Yeonjin, Zhang, Yuxiang, Martinez, Thomas F, Diedrich, Jolene K, Chu, Qian, Moresco, James J, Erb, Michael A, Saghatelian, Alan, Schultz, Peter G, Bollong, Michael J

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 118(4)

مصطلحات موضوعية: Human Genome, Genetics, Generic health relevance, Amino Acid Sequence, Animals, Cattle, Chromatin, Diazomethane, Gene Expression Regulation, Genetic Loci, HEK293 Cells, HeLa Cells, Histones, Humans, K562 Cells, Lysine, Mice, Open Reading Frames, Pan troglodytes, Peptides, Protein Binding, Protein Interaction Mapping, Rats, Sequence Alignment, Sequence Homology, Amino Acid, Transcription, Genetic, Transgenes, Ultraviolet Rays, short open reading frame-encoded peptide, expanded genetic code, photo-crosslinking, transcriptional regulation, Hela Cells

الوصول الحر: https://escholarship.org/uc/item/357677z8Test

المؤلفون: Riva, Laura, Yuan, Shuofeng, Yin, Xin, Martin-Sancho, Laura, Matsunaga, Naoko, Pache, Lars, Burgstaller-Muehlbacher, Sebastian, De Jesus, Paul D, Teriete, Peter, Hull, Mitchell V, Chang, Max W, Chan, Jasper Fuk-Woo, Cao, Jianli, Poon, Vincent Kwok-Man, Herbert, Kristina M, Cheng, Kuoyuan, Nguyen, Tu-Trinh H, Rubanov, Andrey, Pu, Yuan, Nguyen, Courtney, Choi, Angela, Rathnasinghe, Raveen, Schotsaert, Michael, Miorin, Lisa, Dejosez, Marion, Zwaka, Thomas P, Sit, Ko-Yung, Martinez-Sobrido, Luis, Liu, Wen-Chun, White, Kris M, Chapman, Mackenzie E, Lendy, Emma K, Glynne, Richard J, Albrecht, Randy, Ruppin, Eytan, Mesecar, Andrew D, Johnson, Jeffrey R, Benner, Christopher, Sun, Ren, Schultz, Peter G, Su, Andrew I, García-Sastre, Adolfo, Chatterjee, Arnab K, Yuen, Kwok-Yung, Chanda, Sumit K

المصدر: Nature. 586(7827)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Emerging Infectious Diseases, Rare Diseases, Lung, Orphan Drug, Biodefense, Infectious Diseases, Vaccine Related, Pneumonia & Influenza, Pneumonia, Prevention, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Infection, Good Health and Well Being, Adenosine Monophosphate, Alanine, Alveolar Epithelial Cells, Antiviral Agents, Betacoronavirus, COVID-19, Cell Line, Coronavirus Infections, Cysteine Proteinase Inhibitors, Dose-Response Relationship, Drug, Drug Evaluation, Preclinical, Drug Repositioning, Drug Synergism, Gene Expression Regulation, Humans, Hydrazones, Induced Pluripotent Stem Cells, Models, Biological, Morpholines, Pandemics, Pneumonia, Viral, Pyrimidines, Reproducibility of Results, SARS-CoV-2, Small Molecule Libraries, Triazines, Virus Internalization, Virus Replication, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/6p88f41fTest

المؤلفون: Lucki, Natasha C, Villa, Genaro R, Vergani, Naja, Bollong, Michael J, Beyer, Brittney A, Lee, Jae Wook, Anglin, Justin L, Spangenberg, Stephan H, Chin, Emily N, Sharma, Amandeep, Johnson, Kevin, Sander, Philipp N, Gordon, Perry, Skirboll, Stephen L, Wurdak, Heiko, Schultz, Peter G, Mischel, Paul S, Lairson, Luke L

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(13)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biological Sciences, Brain Disorders, Orphan Drug, Stem Cell Research - Nonembryonic - Non-Human, Stem Cell Research, Cancer, Brain Cancer, Neurosciences, Biotechnology, Rare Diseases, Stem Cell Research - Nonembryonic - Human, 5.1 Pharmaceuticals, Aetiology, 2.1 Biological and endogenous factors, Development of treatments and therapeutic interventions, Animals, Antineoplastic Agents, Apoptosis, Astrocytes, Brain Neoplasms, Cell Line, Tumor, Disease Models, Animal, Drug Delivery Systems, Drug Evaluation, Preclinical, Female, Glioblastoma, Heterografts, High-Throughput Screening Assays, Humans, MAP Kinase Kinase Kinases, Mice, Mice, Nude, Neoplastic Stem Cells, Pyroptosis, Receptor-Interacting Protein Serine-Threonine Kinase 2, Receptor-Interacting Protein Serine-Threonine Kinases, glioblastoma, phenotypic drug screening, chemical genetics, target identification, receptor-interacting protein kinase 2

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9rx5d8zhTest

المؤلفون: Dik, David A., Zhang, Nan, Sturgell, Emily J., Sanchez, Brittany B., Chen, Jason S., Webb, Bill, Vanderpool, Kimberly G., Schultz, Peter G.

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar . 118(11), 1-7.

الوصول الحر: https://www.jstor.org/stable/27027626Test

المؤلفون: Mehta, Angad P, Supekova, Lubica, Chen, Jian-Hua, Pestonjamasp, Kersi, Webster, Paul, Ko, Yeonjin, Henderson, Scott C, McDermott, Gerry, Supek, Frantisek, Schultz, Peter G

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(46)

مصطلحات موضوعية: Infectious Diseases, Aetiology, 2.2 Factors relating to the physical environment, Infection, Adenosine Triphosphate, Amino Acid Sequence, Bioengineering, Biological Evolution, Escherichia coli, Mitochondria, Models, Biological, Saccharomyces cerevisiae, Symbiosis, Thiamine, mitochondria, endosymbiotic theory, ADP/ATP translocase, evolution

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5jt1619rTest