نتائج البحث - "Sapkota, Gopal P."

1

دورية أكاديمية

Mapping the substrate landscape of protein phosphatase 2A catalytic subunit PPP2CA

المؤلفون: Brewer, Abigail, Sathe, Gajanan, Pflug, Billie E., Clarke, Rosemary G., Macartney, Thomas J., Sapkota, Gopal P.

المصدر: Brewer , A , Sathe , G , Pflug , B E , Clarke , R G , Macartney , T J & Sapkota , G P 2024 , ' Mapping the substrate landscape of protein phosphatase 2A catalytic subunit PPP2CA ' , iScience , vol. 27 , no. 3 , 109302 . https://doi.org/10.1016/j.isci.2024.109302Test

مصطلحات موضوعية: PP2A, PPP2CA, phosphatase, phosphorylation, kinase, phospho-proteomics, substrate landscape, dTAG, PROTAC, targeted protein degradation, Properties of biomolecules, Protein, Proteomics, Enzymology, /dk/atira/pure/subjectarea/asjc/1000, name=General

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/2d793e84-bbb8-494b-b0a2-fc3edbdf81dfTest

الإتاحة: https://doi.org/10.1016/j.isci.2024.109302Test
https://discovery.dundee.ac.uk/en/publications/2d793e84-bbb8-494b-b0a2-fc3edbdf81dfTest
https://discovery.dundee.ac.uk/ws/files/121836983/PIIS2589004224005236.pdfTest
http://www.scopus.com/inward/record.url?scp=85188210848&partnerID=8YFLogxKTest

View record in BASE

2

دورية أكاديمية

Cluster-randomised trial of community-based screening for eye disease in adults in Nepal: the Village-Integrated Eye Worker Trial II (VIEW II) trial protocol

المؤلفون: O'Brien, Kieran S, Stevens, Valerie M, Byanju, Raghunandan, Kandel, Ram Prasad, Bhandari, Gopal, Bhandari, Sadhan, Melo, Jason S, Porco, Travis C, Lietman, Thomas M, Keenan, Jeremy D, Acharaya, Prakriti, Adhikari, Manmohan, Adihikari, Shree Kanta, Bhattarai, Deepak, Bhattarai, Rabin, Chaudhary, Ajaya, Chaudhary, Bhagiram, Chaudhary, Daya Shankar, Chaudhary, Kishor, Dharel, Krishna Raj, Gautam, Maria, Gautam, Shree Krishna, Ghimire, Aakriti, Ghimire, Bishwash, Ghimire, Narayan, Ghimire, Ramesh, Giri, Gaurav, Giri, Puspa, Gurau, Dhanmaya, Gurung, Ramesh, Kandel, Deepak, Khadka, Simanta, Lamichhane, Benju, Mahato, Pappu, Neupane, Pratikshya, Panday, Ram Janaki, Parajuli, Sabina, Poudel, Radhika Devi, Poudel, Susmita, Pradhan, Sangita, Pun, Suchan, Ranabhat, Bishaka, Ranabhat, Sudha, Rimal, Gaurav, Sapkota, Gopal, Sapkota, Subit, Shah, Ranjeet, Shrestha, Manisha, Silwal, Saraswati, Subedi, Amisha, Subedi, Pradeep, Tamang, Alish, Tandukar, Dilip, Wagle, Nischal Sharma, Yadav, Nilam Kumari, Mishra, Sailesh, Chase, Heidi, Gilbert, Suzanne, Jesudason, Lauren, Tenzing, Chundak, Chaudhary, Shravan, Dhakwha, Parami, Sharma, Prasanna, Shrestha, Apsara, Keenan, Jeremy, Lietman, Thomas, Melo, Jason, O’Brien, Kieran, Porco, Travis, Schwartz, Daniel, Shrestha, Riju, Stamper, Robert, Stevens, Valerie

المصدر: BMJ Open. 10(10)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Ophthalmology and Optometry, Clinical Research, Neurodegenerative, Neurosciences, Eye Disease and Disorders of Vision, Aging, Prevention, Clinical Trials and Supportive Activities, Macular Degeneration, Health Services, Aetiology, 4.4 Population screening, 2.4 Surveillance and distribution, Detection, screening and diagnosis, Eye, Good Health and Well Being, Adult, Aged, Humans, Mass Screening, Middle Aged, Nepal, Randomized Controlled Trials as Topic, San Francisco, Vision, Low, mass screening, glaucoma, diabetic retinopathy, age-related macular degeneration, randomised controlled trial, Group Information for the VIEW II Study Group, Clinical Sciences, Public Health and Health Services, Other Medical and Health Sciences, Biomedical and clinical sciences, Health sciences, Psychology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/3mz8v08mTest

View record in eScholarship

3

دورية أكاديمية

Proteomic approaches advancing targeted protein degradation

المؤلفون: Sathe, Gajanan, Sapkota, Gopal P.

المصدر: Sathe , G & Sapkota , G P 2023 , ' Proteomic approaches advancing targeted protein degradation ' , Trends in Pharmacological Sciences , vol. 44 , no. 11 , pp. 786-801 . https://doi.org/10.1016/j.tips.2023.08.007Test

مصطلحات موضوعية: Targeted protein degradation, PROTAC, Molecular glue, Proteomics, Chemoproteomics, /dk/atira/pure/subjectarea/asjc/3000/3005, name=Toxicology, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/15b6f460-2f3f-4fec-aa7a-3120815eb68dTest

الإتاحة: https://doi.org/10.1016/j.tips.2023.08.007Test
https://discovery.dundee.ac.uk/en/publications/15b6f460-2f3f-4fec-aa7a-3120815eb68dTest
https://discovery.dundee.ac.uk/ws/files/109412654/1-s2.0-S0165614723001773-main.pdfTest

View record in BASE

4

دورية أكاديمية

Discovery of new E3 ligases for alpha-synuclein clearance

المؤلفون: Kocaturk, Nur, Li, Zhiyuan, Ganley, Ian, Sapkota, Gopal P.

المصدر: Kocaturk , N , Li , Z , Ganley , I & Sapkota , G P 2023 , ' Discovery of new E3 ligases for alpha-synuclein clearance ' , Journal of Parkinson's Disease , vol. 13 , no. S1 , P03.05 , pp. 74 . https://doi.org/10.3233/JPD-2399900Test

العلاقة: https://discovery.dundee.ac.uk/en/publications/811a28f6-9525-47e8-b035-648591b4564eTest

الإتاحة: https://doi.org/10.3233/JPD-2399900Test
https://discovery.dundee.ac.uk/en/publications/811a28f6-9525-47e8-b035-648591b4564eTest
http://www.scopus.com/inward/record.url?scp=85164145126&partnerID=8YFLogxKTest

View record in BASE

5

دورية أكاديمية

Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3

المؤلفون: Röth, Sascha, Kocaturk, Nur Mehpare, Sathyamurthi, Preethi S., Carton, Bill, Watt, Matthew, Macartney, Thomas J., Chan, Kwok-Ho, Isidro-Llobet, Albert, Konopacka, Agnieszka, Queisser, Markus A., Sapkota, Gopal P.

المصدر: Röth , S , Kocaturk , N M , Sathyamurthi , P S , Carton , B , Watt , M , Macartney , T J , Chan , K-H , Isidro-Llobet , A , Konopacka , A , Queisser , M A & Sapkota , G P 2023 , ' Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3 ' , Cell Chemical Biology , vol. 30 , no. 10 , pp. 1261-1276.e7 . https://doi.org/10.1016/j.chembiol.2023.07.006Test

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/cce1c275-76ee-4fb5-93f7-4f392856e213Test

الإتاحة: https://doi.org/10.1016/j.chembiol.2023.07.006Test
https://discovery.dundee.ac.uk/en/publications/cce1c275-76ee-4fb5-93f7-4f392856e213Test
https://discovery.dundee.ac.uk/ws/files/115194467/PIIS2451945623002337.pdfTest
http://www.scopus.com/inward/record.url?scp=85173796751&partnerID=8YFLogxKTest

View record in BASE

6

دورية أكاديمية

An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation

المؤلفون: Simpson, Luke M., Fulcher, Luke J., Sathe, Gajanan, Brewer, Abigail, Zhao, Jin-Feng, Squair, Daniel R., Crooks, Jennifer, Wightman, Melanie, Wood, Nicola T., Gourlay, Robert, Varghese, Joby, Soares, Renata F., Sapkota, Gopal P.

المصدر: Simpson , L M , Fulcher , L J , Sathe , G , Brewer , A , Zhao , J-F , Squair , D R , Crooks , J , Wightman , M , Wood , N T , Gourlay , R , Varghese , J , Soares , R F & Sapkota , G P 2023 , ' An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation ' , Cell Chemical Biology , vol. 30 , no. 2 , pp. 188-202 . https://doi.org/10.1016/j.chembiol.2023.01.003Test

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/b0ee5ed6-6d18-4e15-bd77-1c5b5ba96ccaTest

الإتاحة: https://doi.org/10.1016/j.chembiol.2023.01.003Test
https://discovery.dundee.ac.uk/en/publications/b0ee5ed6-6d18-4e15-bd77-1c5b5ba96ccaTest
https://discovery.dundee.ac.uk/ws/files/96764889/1_s2.0_S2451945623000260_main.pdfTest
http://www.scopus.com/inward/record.url?scp=85148030514&partnerID=8YFLogxKTest

View record in BASE

7

تقرير

Characterization of protein complexes using chemical cross-linking coupled electrospray mass spectrometry

المؤلفون: Cummins, Timothy D., Sapkota, Gopal P.

مصطلحات موضوعية: Quantitative Biology - Molecular Networks, Quantitative Biology - Biomolecules

الوصول الحر: http://arxiv.org/abs/1606.04247Test

View record in Arxiv

8

دورية أكاديمية

Target protein localization and its impact on PROTAC-mediated degradation

المؤلفون: Simpson, Luke M., Glennie, Lorraine, Brewer, Abigail, Zhao, Jin-Feng, Crooks, Jennifer, Shpiro, Natalia, Sapkota, Gopal P.

المصدر: Simpson , L M , Glennie , L , Brewer , A , Zhao , J-F , Crooks , J , Shpiro , N & Sapkota , G P 2022 , ' Target protein localization and its impact on PROTAC-mediated degradation ' , Cell Chemical Biology , vol. 29 , no. 10 , pp. 1482-1504.e7 . https://doi.org/10.1016/j.chembiol.2022.08.004Test

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/1b78f0bd-7662-418b-a4d9-33149454ca2aTest

الإتاحة: https://doi.org/10.1016/j.chembiol.2022.08.004Test
https://discovery.dundee.ac.uk/en/publications/1b78f0bd-7662-418b-a4d9-33149454ca2aTest
https://discovery.dundee.ac.uk/ws/files/80555670/PIIS2451945622003129.pdfTest
http://www.scopus.com/inward/record.url?scp=85140068494&partnerID=8YFLogxKTest

View record in BASE

9

دورية أكاديمية

The promise of targeted protein degradation approaches.

المؤلفون: Daniels, Danette L.¹ (AUTHOR) ddaniels@foghorntx.com, Sapkota, Gopal P.^1,2 (AUTHOR) g.sapkota@dundee.ac.uk, Jones, Lyn H.^1,3,4 (AUTHOR) lyn_jones@dfci.harvard.edu

المصدر: Trends in Pharmacological Sciences. Nov2023, Vol. 44 Issue 11, p746-749. 4p.

مصطلحات موضوعية: *PROTEOLYSIS

10

دورية أكاديمية

A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications

المؤلفون: Stacey, Peter, Lithgow, Hannah, Lewell, Xiao, Konopacka, Agnieszka, Besley, Stephen, Green, Georgina, Whatling, Ryan, Law, Robert, Röth, Sascha, Sapkota, Gopal P., Smith, Ian E. D., Burley, Glenn A., Harling, John, Benowitz, Andrew B., Queisser, Markus A., Muelbaier, Marcel

المصدر: Stacey , P , Lithgow , H , Lewell , X , Konopacka , A , Besley , S , Green , G , Whatling , R , Law , R , Röth , S , Sapkota , G P , Smith , I E D , Burley , G A , Harling , J , Benowitz , A B , Queisser , M A & Muelbaier , M 2021 , ' A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications ' , SLAS Discovery , vol. 26 , no. 7 , pp. 885-895 ....

مصطلحات موضوعية: E3 ubiquitin ligases, HTE, HaloTag, PROTACs, phenotypic screening, targeted protein degradation, /dk/atira/pure/subjectarea/asjc/1300/1305, name=Biotechnology, /dk/atira/pure/subjectarea/asjc/1600/1602, name=Analytical Chemistry, /dk/atira/pure/subjectarea/asjc/1300/1303, name=Biochemistry, /dk/atira/pure/subjectarea/asjc/1300/1313, name=Molecular Medicine

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/7d29dacc-0c01-4fbb-9cb6-f43c00d726a6Test

الإتاحة: https://doi.org/10.1177/24725552211017517Test
https://discovery.dundee.ac.uk/en/publications/7d29dacc-0c01-4fbb-9cb6-f43c00d726a6Test
https://discovery.dundee.ac.uk/ws/files/72521915/Stacey_etal_SLASD_2021_A_phenotypic_approach_for_the_identification_of_new_molecules.pdfTest
http://www.scopus.com/inward/record.url?scp=85106688745&partnerID=8YFLogxKTest

View record in BASE

تنقيح النتائج