نتائج البحث - "Sander, Brooks"

المصدر: Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Translational Psychiatry, 10(1). NATURE PUBLISHING GROUP
Translational Psychiatry, 10(1):308. Nature Publishing Group

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b397cd405d1b36d3e9fc6b0fedee7f63Test
https://hdl.handle.net/1887/3184546Test

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Clinical pharmacology of the dual orexin receptor antagonist ACT-541468 in elderly subjects: Exploration of pharmacokinetics, pharmacodynamics and tolerability following single-dose morning and repeated-dose evening administration

المؤلفون: Joop M. A. van Gerven, Sander Brooks, Margaux Boehler, Jasper Dingemanse, Rob Zuiker, Clemens Muehlan

المصدر: Journal of Psychopharmacology, 34(3), 326-335. SAGE PUBLICATIONS LTD

مصطلحات موضوعية: Male, Pyrrolidines, medicine.drug_class, Pharmacology, 030226 pharmacology & pharmacy, elderly, law.invention, 03 medical and health sciences, next-day effects, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, law, medicine, Saccades, pharmacodynamics, Humans, Pharmacology (medical), Postural Balance, Aged, Aged, 80 and over, Clinical pharmacology, Dose-Response Relationship, Drug, business.industry, multiple-dose, excessive daytime sleepiness, Antagonist, Imidazoles, Orexin receptor, Orexin, Psychiatry and Mental health, Tolerability, Patient Satisfaction, Pharmacodynamics, Sedative, Female, Orexin Receptor Antagonists, business, pharmacokinetics, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8268d69417432eaaad1bb072888efbdbTest
https://hdl.handle.net/1887/3181508Test

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341 Acute effects of seltorexant, a selective orexin-2 antagonist (JNJ- 42847922), on driving after bedtime administration

المؤلفون: P. Van der Ark, Gabriel E. Jacobs, I. Kezic, J.M.A. van Gerven, Sander Brooks, A Savitz, Rob Zuiker

المصدر: Sleep. 44:A136-A136

مصطلحات موضوعية: Acute effects, business.industry, Physiology (medical), Antagonist, Medicine, Neurology (clinical), Pharmacology, business, Bedtime, Administration (government), Orexin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::f1a13f8e246b16592c5a84ce03d55bdfTest
https://doi.org/10.1093/sleep/zsab072.340Test

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The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia

المؤلفون: I. Kezic, Sander Brooks, Rob Zuiker, Joop M. A. van Gerven, Peter de Boer, Wayne C. Drevets, Remy Luthringer, Peter van der Ark, Justine M. Kent, Luc Van Nueten, Guido van Amerongen, Gabriel E. Jacobs

المصدر: Journal of Psychopharmacology, 33(2), 202-209

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Polysomnography, insomnia, orexin 2 antagonist, Placebo, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Double-Blind Method, Internal medicine, Sleep Initiation and Maintenance Disorders, medicine, Insomnia, Humans, Pharmacology (medical), Pyrroles, Aged, Pharmacology, Depressive Disorder, Major, Cross-Over Studies, Dose-Response Relationship, Drug, business.industry, Depression, Antagonist, Middle Aged, Triazoles, medicine.disease, Crossover study, Sleep in non-human animals, Antidepressive Agents, 030227 psychiatry, Psychiatry and Mental health, Mood, Pyrimidines, Treatment Outcome, Major depressive disorder, Antidepressant, Female, Orexin Receptor Antagonists, medicine.symptom, business, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8373ae9a16200258305ec1e18d2b3cfTest
https://hdl.handle.net/1887/119782Test

9

Multiple-dose clinical pharmacology of ACT-541468, a novel dual orexin receptor antagonist, following repeated-dose morning and evening administration

المؤلفون: Rob Zuiker, Joop M. A. van Gerven, Sander Brooks, Clemens Muehlan, Jasper Dingemanse

المصدر: European Neuropsychopharmacology, 29(7), 847-857. ELSEVIER SCIENCE BV

مصطلحات موضوعية: Adult, Male, Evening, Insomnia, Pyrrolidines, Adolescent, Administration, Oral, Pharmacology, Neuropsychological Tests, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Pharmacokinetics, Double-Blind Method, Reaction Time, Medicine, Humans, Hypnotics and Sedatives, Pharmacology (medical), Wakefulness, Biological Psychiatry, Morning, Multiple-dose, Dose-Response Relationship, Drug, business.industry, Area under the curve, Imidazoles, Orexin receptor, 030227 psychiatry, Psychiatry and Mental health, Neurology, Tolerability, Pharmacodynamics, Digit symbol substitution test, Orexin receptor antagonist, Female, Orexin Receptor Antagonists, Neurology (clinical), business, Sleep, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6ddcf16888f8fd0122523826b32253Test
https://pubmed.ncbi.nlm.nih.gov/31221502Test

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O.25Phase 1 clinical trial of losmapimod in FSHD: safety, tolerability and target engagement

المؤلفون: Sander Brooks, Geert Jan Groeneveld, Michelle Mellion, E. van Brummelen, Diego Cadavid, Lisa Pagan, U.A. Badrising, D. Thompson, Michelle Hage, L. Ronco, B.G.M. van Engelen

المصدر: Neuromuscular Disorders. 29:S123

مصطلحات موضوعية: Clinical trial, medicine.medical_specialty, Neurology, Losmapimod, business.industry, Pediatrics, Perinatology and Child Health, Target engagement, Physical therapy, Medicine, Safety tolerability, Neurology (clinical), business, Genetics (clinical)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e406b32859d3b3eb4523fa8f59cf49b0Test
https://doi.org/10.1016/j.nmd.2019.06.308Test

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