يعرض 1 - 10 نتائج من 398 نتيجة بحث عن '"Sanchez-Ruiz, Jose M"', وقت الاستعلام: 1.08s تنقيح النتائج
  1. 1
    Enhancing a de novo enzyme activity by computationally-focused ultra-low-throughput screening

    المؤلفون: Risso, Valeria A., Romero-Rivera, Adrian, Gutierrez-Rus, Luis I., Ortega-Muñoz, Mariano, Santoyo-Gonzalez, Francisco, Gavira, Jose A., Sanchez-Ruiz, Jose M., Kamerlin, Shina C. L., 1981

    المصدر: Chemical Science. 11(24):6134-6148

    وصف الملف: electronic

    الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-420100Test
    https://doi.org/10.1039/d0sc01935fTest
    https://uu.diva-portal.org/smash/get/diva2:1470761/FULLTEXT01.pdfTest

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  2. 2
    Manipulating Conformational Dynamics To Repurpose Ancient Proteins for Modern Catalytic Functions

    المؤلفون: Gardner, Jasmine M., Biler, Michal, Risso, Valeria A., Sanchez-Ruiz, Jose M., Kamerlin, Shina C. Lynn, 1981

    المصدر: ACS Catalysis. 10(9):4863-4870

    وصف الملف: electronic

    الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-412592Test
    https://doi.org/10.1021/acscatal.0c00722Test
    https://uu.diva-portal.org/smash/get/diva2:1438205/FULLTEXT01.pdfTest

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  3. 3
    دورية أكاديمية
    Engineering protein assemblies with allosteric control via monomer fold-switching

    المؤلفون: Campos, Luis A, Sharma, Rajendra, Alvira, Sara, Ruiz, Federico M, Ibarra-Molero, Beatriz, Sadqi, Mourad, Alfonso, Carlos, Rivas, Germán, Sanchez-Ruiz, Jose M, Romero Garrido, Antonio, Valpuesta, José M, Muñoz, Victor

    المصدر: Nature Communications. 10(1)

    مصطلحات موضوعية: Macromolecular and Materials Chemistry, Chemical Sciences, Bioengineering, Generic health relevance, Allosteric Regulation, Cloning, Molecular, Molecular Docking Simulation, Molecular Dynamics Simulation, Mutation, Protein Engineering, Protein Folding, Protein Multimerization, Protein Structure, Secondary, Proteins, Recombinant Proteins, Serine Proteases, Serine Proteinase Inhibitors

    وصف الملف: application/pdf

    الوصول الحر: https://escholarship.org/uc/item/7xg280rdTest
    https://escholarship.org/content/qt7xg280rd/qt7xg280rd.pdfTest

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  4. 4
    دورية أكاديمية
    Cell Survival Enabled by Leakage of a Labile Metabolic Intermediate

    المؤلفون: Medina-Carmona, Encarnacion, Gutierrez-Rus, Luis I, Manssour-Triedo, Fadia, Newton, Matilda S, Gamiz-Arco, Gloria, Mota, Antonio J, Reiné, Pablo, Cuerva, Juan Manuel, Ortega-Muñoz, Mariano, Andrés-León, Eduardo, Ortega-Roldan, Jose Luis, Seelig, Burckhard, Ibarra-Molero, Beatriz, Sanchez-Ruiz, Jose M

    مصطلحات موضوعية: Q Science, QH581.2 Cell Biology

    وصف الملف: application/pdf

    العلاقة: https://kar.kent.ac.uk/100205/7/Ortega-Roldan%20Cell%20Survival%20Enabled%20PDF.pdfTest; Medina-Carmona, Encarnacion, Gutierrez-Rus, Luis I, Manssour-Triedo, Fadia, Newton, Matilda S, Gamiz-Arco, Gloria, Mota, Antonio J, Reiné, Pablo, Cuerva, Juan Manuel, Ortega-Muñoz, Mariano, Andrés-León, Eduardo, and others. Ortega-Roldan, Jose Luis, Seelig, Burckhard, Ibarra-Molero, Beatriz, and Sanchez-Ruiz, Jose M (hide) (2023) Cell Survival Enabled by Leakage of a Labile Metabolic Intermediate. Molecular Biology and Evolution, 40 (3). Article Number msad032. ISSN 1537-1719. (doi:10.1093/molbev/msad032 ) (KAR id:100205 )

    الإتاحة: https://doi.org/10.1093/molbev/msad032Test
    https://kar.kent.ac.uk/100205Test/
    https://kar.kent.ac.uk/100205/7/Ortega-Roldan%20Cell%20Survival%20Enabled%20PDF.pdfTest

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  5. 5
    دورية أكاديمية
    Protection of Catalytic Cofactors by Polypeptides as a Driver for the Emergence of Primordial Enzymes

    المؤلفون: Gutierrez-Rus, Luis I., Gamiz-Arco, Gloria, Gavira Gallardo, J. A., Gaucher, Eric A., Risso, Valeria A., Sánchez-Ruiz, Jose M.

    المساهمون: Ministerio de Ciencia e Innovación (España), Human Frontier Science Program, Department of Defense (US), National Institutes of Health (US), National Science Foundation (US)

    مصطلحات موضوعية: Catalysis, Heme, Peptides, Polypeptide, Catalyst, Chemical reaction, Controlled study, Effective concentration, Enzyme kinetics

    العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2020-116261GB-I00/ES/APLICACIONES BIOTECNOLOGICAS DE CRISTALES PROTEICOS/; info:eu-repo/grantAgreement/MINECO//PID2021-124534OB-100; Publisher's version; http://dx.doi.org/10.1093/molbev/msad126Test; Sí; Molecular Biology and Evolution 40 (2023); http://hdl.handle.net/10261/346219Test

    الإتاحة: https://doi.org/10.1093/molbev/msad126Test
    http://hdl.handle.net/10261/346219Test

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  6. 6
    دورية أكاديمية
    Immunoanalytical Approach for Detecting and Identifying Ancestral Peptide Biomarkers in Early Earth Analogue Environments

    المؤلفون: Severino, Rita, Moreno-Paz, Mercedes, Puente-Sánchez, Fernando, Sánchez-García, Laura, Risso, Valeria A., Sanchez-Ruiz, Jose M., Cabrol, Nathalie, Parro, Victor

    المساهمون: FP7 People: Marie-Curie Actions, European Regional Development Fund, National Aeronautics and Space Administration, Instituto de Salud Carlos III, Instituto Nacional de T?cnica Aeroespacial, Agencia Estatal de Investigaci?n, Ministerio de Ciencia e Innovaci?n

    المصدر: Analytical Chemistry ; volume 95, issue 12, page 5323-5330 ; ISSN 0003-2700 1520-6882

    مصطلحات موضوعية: Analytical Chemistry

    الإتاحة: https://doi.org/10.1021/acs.analchem.2c05386Test

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  7. 7
    Cooperativity and flexibility in enzyme evolution

    المؤلفون: Pabis, Anna, Risso, Valeria A., Sanchez-Ruiz, Jose M., Kamerlin, Shina C. Lynn, 1981

    المصدر: Current opinion in structural biology. 48:83-92

    وصف الملف: electronic

    الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-351054Test
    https://doi.org/10.1016/j.sbi.2017.10.020Test
    https://uu.diva-portal.org/smash/get/diva2:1211832/FULLTEXT01.pdfTest

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  8. 8
    Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase

    المؤلفون: Gamiz-Arco, Gloria, Gutierrez-Rus, Luis I., Risso, Valeria A., Ibarra-Molero, Beatriz, Hoshino, Yosuke, Petrovic, Dusan, Justicia, Jose, Manuel Cuerva, Juan, Romero-Rivera, Adrian, Seelig, Burckhard, Gavira, Jose A., Kamerlin, Shina C. Lynn, 1981, Gaucher, Eric A., Sanchez-Ruiz, Jose M.

    المصدر: Nature Communications. 12

    وصف الملف: electronic

    الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-435192Test
    https://doi.org/10.1038/s41467-020-20630-1Test
    https://uu.diva-portal.org/smash/get/diva2:1531471/FULLTEXT01.pdfTest

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  9. 9
    دورية أكاديمية
    Hinge-shift mechanism as a protein design principle for the evolution of β-lactamases from substrate promiscuity to specificity

    المؤلفون: Modi, Tushar, Risso, Valeria A., Martínez-Rodríguez, Sergio, Gavira, Jose A., Mebrat, Mubark D., Van Horn, Wade D., Sanchez-Ruiz, Jose M., Banu Ozkan, S.

    المساهمون: Ministerio de Economía, Industria y Competitividad (España), European Commission, Human Frontier Science Program, Gordon and Betty Moore Foundation, National Institutes of Health (US), National Science Foundation (US), Junta de Andalucía

    مصطلحات موضوعية: Amino Acid Sequence, Beta-Lactamases, Catalytic Domain, Computational Biology, Escherichia coli, Evolution, Molecular, Molecular Dynamics Simulation, Penicillins, Protein Conformation, Substrate Specificity

    العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO//BIO2015-66426-R/ES/INGENIERIA Y EVOLUCION DE ENZIMAS DE NOVO CON ACTIVIDADES NO NATURALES/; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/RTI2018-097142-B-I00/ES/PROTEINAS ANCESTRALES EN ORGANISMOS MODERNOS/; Publisher's version; http://dx.doi.org/10.1038/s41467-021-22089-0Test; Sí; Nature Communications 12 (2021); http://hdl.handle.net/10261/265220Test; http://dx.doi.org/10.13039/100000936Test; http://dx.doi.org/10.13039/100004412Test; http://dx.doi.org/10.13039/501100011011Test; http://dx.doi.org/10.13039/100000002Test; http://dx.doi.org/10.13039/501100010198Test; http://dx.doi.org/10.13039/100000001Test; http://dx.doi.org/10.13039/501100000780Test

    الإتاحة: https://doi.org/10.1038/s41467-021-22089-0Test
    https://doi.org/10.13039/100000936Test
    https://doi.org/10.13039/100004412Test
    https://doi.org/10.13039/501100011011Test
    https://doi.org/10.13039/100000002Test
    https://doi.org/10.13039/501100010198Test
    https://doi.org/10.13039/100000001Test
    https://doi.org/10.13039/501100000780Test
    http://hdl.handle.net/10261/265220Test

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  10. 10
    دورية أكاديمية
    Combining Ancestral Reconstruction with Folding-Landscape Simulations to Engineer Heterologous Protein Expression: Engineering heterologous protein expression

    المؤلفون: Gamiz-Arco, Gloria, Risso, Valeria A., Gaucher, Eric A., Gavira Gallardo, J. A., Naganathan, Athi N., Ibarra-Molero, Beatriz, Sánchez-Ruiz, Jose M.

    المساهمون: Human Frontier Science Program, National Science Foundation (US), National Institutes of Health (US), Ministerio de Ciencia e Innovación (España)

    مصطلحات موضوعية: Ancestral sequence reconstruction, Computational modelling of protein folding landscapes, Heterologous protein expression, Proteins from uncultured organisms, Obligate symbionts

    العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/MINECO//RTI-2018-097142-B-100; info:eu-repo/grantAgreement/MINECO//BIO2016-74875-P; Publisher's version; http://dx.doi.org/10.1016/j.jmb.2021.167321Test; Sí; Journal of Molecular Biology 433(24) (2021); http://hdl.handle.net/10261/261283Test; http://dx.doi.org/10.13039/100004412Test; http://dx.doi.org/10.13039/501100004837Test; http://dx.doi.org/10.13039/100000002Test; http://dx.doi.org/10.13039/100000001Test

    الإتاحة: https://doi.org/10.1016/j.jmb.2021.167321Test
    https://doi.org/10.13039/100004412Test
    https://doi.org/10.13039/501100004837Test
    https://doi.org/10.13039/100000002Test
    https://doi.org/10.13039/100000001Test
    http://hdl.handle.net/10261/261283Test

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