المؤلفون: James F. Howard, Vera Bril, Tuan Vu, Chafic Karam, Stojan Peric, Jan L. De Bleecker, Hiroyuki Murai, Andreas Meisel, Said R. Beydoun, Mamatha Pasnoor, Antonio Guglietta, Benjamin Van Hoorick, Sophie Steeland, Caroline T’joen, Kimiaki Utsugisawa, Jan Verschuuren, Renato Mantegazza, the ADAPT+ Study Group

المصدر: Frontiers in Neurology, Vol 14 (2024)

مصطلحات موضوعية: efgartigimod, myasthenia gravis, neonatal Fc receptor, FcRn, IgG recycling, antibody fragment, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fneur.2023.1284444/fullTest; https://doaj.org/toc/1664-2295Test

الوصول الحر: https://doaj.org/article/1a89a0788ce640369ff168f37dc4e637Test

المؤلفون: Suraj Muley, Said R. Beydoun

المصدر: Therapeutic Advances in Neurological Disorders, Vol 16 (2023)

مصطلحات موضوعية: Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: https://doaj.org/toc/1756-2864Test

الوصول الحر: https://doaj.org/article/19d6d59675a74575b5e731fdc6f2460eTest

المؤلفون: Said R. Beydoun, Khema R. Sharma, Bassam A. Bassam, Michael T. Pulley, Jeffrey Z. Shije, Ayman Kafal

المصدر: Frontiers in Neurology, Vol 12 (2021)

مصطلحات موضوعية: CIDP, IVIg, SCIg, IG therapy, dosing strategies, pharmacokinetics, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fneur.2021.638816/fullTest; https://doaj.org/toc/1664-2295Test

الوصول الحر: https://doaj.org/article/91bb710c233e4e93b868047befb65fbaTest

المؤلفون: Richard J. Nowak, Srikanth Muppidi, Said R. Beydoun, Fanny L. O'Brien, Marcus Yountz, James F. Howard

المصدر: Frontiers in Neurology, Vol 11 (2020)

مصطلحات موضوعية: eculizumab, myasthenia gravis, immunosuppressive therapy, refractory, acetylcholine receptor, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fneur.2020.556104/fullTest; https://doaj.org/toc/1664-2295Test

الوصول الحر: https://doaj.org/article/c2c624d8ca5145e090511024f093e78eTest

المؤلفون: James F. Howard, Vera Bril, Tuan Vu, Chafic Karam, Stojan Peric, Jan L. De Bleecker, Hiroyuki Murai, Andreas Meisel, Said R. Beydoun, Mamatha Pasnoor, Antonio Guglietta, Benjamin Van Hoorick, Sophie Steeland, Caroline T’joen, Kimiaki Utsugisawa, Jan Verschuuren, Renato Mantegazza, the ADAPT+ Study Group

مصطلحات موضوعية: Neurology and Neuromuscular Diseases, Neurogenetics, efgartigimod, myasthenia gravis, neonatal Fc receptor, FcRn, IgG recycling, antibody fragment, autoantibody reduction, neonatal Fc receptor antagonist

العلاقة: https://figshare.com/articles/dataset/Table_2_Long-term_safety_tolerability_and_efficacy_of_efgartigimod_ADAPT_interim_results_from_a_phase_3_open-label_extension_study_in_participants_with_generalized_myasthenia_gravis_DOCX/25009859Test

الإتاحة: https://doi.org/10.3389/fneur.2023.1284444.s003Test
https://figshare.com/articles/dataset/Table_2_Long-term_safety_tolerability_and_efficacy_of_efgartigimod_ADAPT_interim_results_from_a_phase_3_open-label_extension_study_in_participants_with_generalized_myasthenia_gravis_DOCX/25009859Test

المؤلفون: James F. Howard, Vera Bril, Tuan Vu, Chafic Karam, Stojan Peric, Jan L. De Bleecker, Hiroyuki Murai, Andreas Meisel, Said R. Beydoun, Mamatha Pasnoor, Antonio Guglietta, Benjamin Van Hoorick, Sophie Steeland, Caroline T’joen, Kimiaki Utsugisawa, Jan Verschuuren, Renato Mantegazza, the ADAPT+ Study Group

مصطلحات موضوعية: Neurology and Neuromuscular Diseases, Neurogenetics, efgartigimod, myasthenia gravis, neonatal Fc receptor, FcRn, IgG recycling, antibody fragment, autoantibody reduction, neonatal Fc receptor antagonist

العلاقة: https://figshare.com/articles/figure/Image_1_Long-term_safety_tolerability_and_efficacy_of_efgartigimod_ADAPT_interim_results_from_a_phase_3_open-label_extension_study_in_participants_with_generalized_myasthenia_gravis_jpeg/25009853Test

الإتاحة: https://doi.org/10.3389/fneur.2023.1284444.s001Test
https://figshare.com/articles/figure/Image_1_Long-term_safety_tolerability_and_efficacy_of_efgartigimod_ADAPT_interim_results_from_a_phase_3_open-label_extension_study_in_participants_with_generalized_myasthenia_gravis_jpeg/25009853Test

المؤلفون: Leila Darki, Said R. Beydoun, Arash Jalali-Sohi

المصدر: Journal of Clinical Neuromuscular Disease. 22:97-102

مصطلحات موضوعية: Diarrhea, Male, 0301 basic medicine, Mitochondrial DNA, Pathology, medicine.medical_specialty, Encephalopathy, Mutation, Missense, 030105 genetics & heredity, medicine.disease_cause, DNA, Mitochondrial, Polyneuropathies, Young Adult, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Muscular Dystrophy, Oculopharyngeal, Humans, Medicine, Missense mutation, Thymidine phosphorylase, Gene, Thymidine Phosphorylase, Mutation, Ophthalmoplegia, business.industry, Intestinal Pseudo-Obstruction, Nausea, General Medicine, medicine.disease, Magnetic Resonance Imaging, Neurology, chemistry, Neurology (clinical), business, Thymidine, Constipation, Polyneuropathy, 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74cecdc171b62d11e912ba105af92c3Test
https://doi.org/10.1097/cnd.0000000000000326Test

المؤلفون: Bassam A. Bassam, Jeffrey Z. Shije, Michael Pulley, Said R. Beydoun, Khema Sharma, Ayman Kafal

المصدر: Frontiers in Neurology, Vol 12 (2021)
Frontiers in Neurology

مصطلحات موضوعية: IVIg, Mini Review, CIDP, Pharmacology, dosing strategies, lcsh:RC346-429, Mini review, Bolus (medicine), Pharmacokinetics, Medicine, Dosing, Adverse effect, lcsh:Neurology. Diseases of the nervous system, wear-off effect, biology, business.industry, IG therapy, SCIg, Dose optimization, Neurology, biology.protein, Biomarker (medicine), Neurology (clinical), Antibody, business, Ig concentrations, pharmacokinetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc32c3c9dcf8112b0bb14f2624fcb1bTest
https://www.frontiersin.org/articles/10.3389/fneur.2021.638816/fullTest

المؤلفون: Samuel Guzman, Kyle Hurth, Said R. Beydoun, Leila Darki, Anna Mathew, Robert C. Bucelli, Arash Jalali-Sohi

المصدر: Clinical neurology and neurosurgery. 207

مصطلحات موضوعية: Pathology, medicine.medical_specialty, Adolescent, Muscle Proteins, Muscle disorder, Gene mutation, Muscular Diseases, medicine, Humans, Myopathy, Gene, Inclusion Bodies, Muscle biopsy, medicine.diagnostic_test, business.industry, Intracellular Signaling Peptides and Proteins, Muscle weakness, General Medicine, LIM Domain Proteins, FHL1, Mutation, Surgery, Female, Neurology (clinical), medicine.symptom, Contracture, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f589d7d9bd095f8d1c400f5aa4b6f405Test
https://pubmed.ncbi.nlm.nih.gov/34273663Test

المؤلفون: Lucy Lam, Jiri Pitha, John Vissing, Laura Fionda, Denis Korobko, Michael Pulley, Tony Vangeneugden, Silvia Bonanno, Nobuhiro Ido, Jerrica Farias, Jafar Shabanpour, James Gilchrist, Girolamo Alfieri, Gyorgyi Szabo, Carlayne E. Jackson, Eduardo Ng, Csilla Rozsa, Hans D. Katzberg, Carlo Antozzi, Aleksandra Golenia, Sayaka Ishida, Temur Margania, Andrzej Szczudlik, Richard J. Barohn, Mari Suzuki., Robert Henegar, Kaoru Sakuma, Evanthia Bernitsas, Elena Lapochka, Yukiko Ozawa, Tomihiro Imai, Debbie Hastings, Antonio Guglietta, Benjamin Frishberg, Elena Antipenko, Vera Bril, Stanislav Vohanka, Isela Hernandez, Ivo Bozovic, Ilona Vergunova, Lorenzo Maggi, Andreas Meisel, Ali Malekniazi, Tahseen Mozaffar, Emmanuelle Salort-Campana, Yasmin Camberos, Jan J.G.M. Verschuuren, Masayuki Masuda, Masanori Takahashi, Yoshihiko Okubo, Marek Smilowski, Yasushi Suzuki, Mary Wagoner, Andrew Heim, David Bors, Chiho Watanabe, Fiammetta Vanoli, Antonio Reia, Zubair Quraishi, Omar Jawdat, Makoto Samukawa, Gregory Sahagian, Gedeonne Margo Jakab, Eiichi Nomura, Samantha Colgan, Cindy Benzel, Ayako Mori, Annabel M. Ruiter, Ratna Bharavaju-Sanka, Roman Shakarishvili, Victoria Cannon, Malkova Nadezhda, Tomas Horak, Anna Kostera-Pruszczyk, Eniko Szabo, Emilien Delmont, Alexander Tsiskaridze, Lubna Daniyal, Vidosava Rakocevic Stojanovic, Szilvia Toth, Siegfried Kohler, Iveta Novakova, Katherine Roath, Kazuna Ikeda, Salma Akhter, Claudia Heibutzki, Martijn R. Tannemaat, Marta Pinkosz, Mads Peter Godtfeldt Stemmerik, Chafic Karam, Irys Caristo, Carolyn Paiz, Josef Bednarik, Monika Frasinska, Stefania Morino, Norianne Pimentel, Kanako Minemoto, Rekha Pillai, Linda Wagemaekers, Annelien De Pue, Irina Poverennova, Katerina Reguliova, Jana Junkerova, Angela Marsili, Anne-Marie Peters, Maren Wyckmans, Michaela Tyblova, Debbie Eggleston, Anne Mette Ostergaard Autzen, Takamichi Sugimoto, Kuldeep Kumar Khatri, Niraja Suresh, Jan De Bleecker, Lea Gerischer, Grazyna Zwolinska, Kevin R Keene, Yosuke Onishi, Francesco Saccà, Zaeem A. Siddiqi, Marjolein Van Heur, Jeffrey Statland, Tatiana Romanova, Diana Dimitrova, Stojan Peric, Tomoko Tsuda, Cathy Bailey, Lubov Urtaeva, Lizzie Zafirakos, Katherine Ruzhansky, Tomoya Kubota, Angela Campanella, Nadezhda Kuznetsova, Sarah Jones, Giovanni Antonini, Hiroyuki Murai, Luca Leonardi, Alan R. Berger, Jonathan Baets, Peter Ulrichts, Said R. Beydoun, Michala Jakubikova, Mamatha Pasnoor, James F. Howard, Leila Darki, Katerina Havelkova, Namita Goyal, Akiyuki Uzawa, Tia Nguyen, Miki Takaki, Matteo Garibaldi, Manisha Kak, Ivonne Turner, Aude-Marie Grapperon, Mageda Horakova, Yuebing Li, Ivana Basta, Lech Szczechowski, Shabber Mannan, Aneta Pasko, Caroline Vinck, Riccardo Giossi, Rudolf Mercelis, Ivana Jurajdova, Lesly Welsh, Małgorzata Bilińska, Marek Halas, Dragana Lavrnic, Kimiaki Utsugisawa, Todd Levine, Erik Velasquez, Daisuke Yamamoto, Constantine Farmakidis, John Anthony Morren, Sarah Hoffman, Manisha Chopra, Shingo Konno, Rita Frangiamore, Kelly Jia, Jana Horakova, Anna Melnikova, Piotr Szczudlik, Ali Habib, Giorgia Puorro, Michael D. Weiss, Robert P. Lisak, Hiroyuki Naito, Shahram Attarian, Hiroko Nakamura, Shin Hisahara, Mazen M. Dimachkie, Genya Watanabe, Duaa Jabari, Ekaterina Bulatova, Angela Genge, Makiko Naito, Melissa Currence, Henning Andersen, Katrien De Mey, Kathy de Koning, Yuen T. So, Chiara Pane, Renato Mantegazza, Rebecca Traub, Manato Yasuda, Amy Visser, Dike Remstedt, Yuka Takematsu, Frauke Stascheit, Ayumi Kamei, Tuan Vu, Tulio E. Bertorini, Ludivine Kouton, Neelam Goyal, Flicia Mada, Nizar Chahin, Mihiro Shimizu, Srikanth Muppidi, Erina Sugano

المصدر: ADAPT Investigator Study Group 2021, ' Safety, efficacy, and tolerability of efgartigimod in patients with generalised myasthenia gravis (ADAPT) : a multicentre, randomised, placebo-controlled, phase 3 trial ', The Lancet Neurology, vol. 20, no. 7, pp. 526-536 . https://doi.org/10.1016/S1474-4422Test(21)00159-9
The lancet neurology

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Population, fc fragment, Placebo, Antibodies, Monoclonal, Humanized, law.invention, efgartigimod, myasthenia gravis, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, Double-Blind Method, law, Internal medicine, Activities of Daily Living, Myasthenia Gravis, medicine, Clinical endpoint, Humans, Receptors, Cholinergic, Dosing, Longitudinal Studies, education, Biology, Autoantibodies, education.field_of_study, business.industry, Headache, Antibodies, Monoclonal, Middle Aged, medicine.disease, Myasthenia gravis, 3. Good health, Immunoglobulin Fc Fragments, Clinical trial, Chemistry, 030104 developmental biology, Tolerability, Female, Human medicine, Neurology (clinical), business, 030217 neurology & neurosurgery

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be57499b1a7a7d2e60c700dc07fa4eeTest
https://pubmed.ncbi.nlm.nih.gov/34426685Test