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1دورية أكاديمية
المؤلفون: Jinseon Jeong, Young-Jun Kim, Sun Young Yoon, Yong-Jae Kim, Joo Heon Kim, Ki-Young Sohn, Heung-Jae Kim, Yong-Hae Han, Saeho Chong, Jae Wha Kim
المصدر: PLoS ONE, Vol 11, Iss 3, p e0151758 (2016)
وصف الملف: electronic resource
العلاقة: http://europepmc.org/articles/PMC4807014?pdf=renderTest; https://doaj.org/toc/1932-6203Test
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2
المؤلفون: Sarah Bond, Saeho Chong, Tuyen Nguyen, Justin Darcy, Saket Agarwal, Maja M. Janas, Jing-Tao Wu, Samantha Chigas, Yongli Gu, Ruth Allard
المصدر: Nucleic Acid Therapeutics
مصطلحات موضوعية: 0301 basic medicine, Small interfering RNA, Acetylgalactosamine, ASGPR, protein binding, Asialoglycoprotein Receptor, Plasma protein binding, Biochemistry, Protein–protein interaction, 03 medical and health sciences, 0302 clinical medicine, RNA interference, Drug Discovery, Genetics, Humans, RNA, Small Interfering, Molecular Biology, Chemistry, Blood Proteins, Ligand (biochemistry), Small molecule, Blood proteins, carbohydrates (lipids), GalNAc conjugate, 030104 developmental biology, siRNA, RNAi, 030220 oncology & carcinogenesis, Hepatocytes, Molecular Medicine, RNA Interference, lipids (amino acids, peptides, and proteins), Asialoglycoprotein receptor, Brief Communications
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03774b8b68b07398a9b85a3521e562fTest
https://doi.org/10.1089/nat.2020.0919Test -
3
المؤلفون: Krishna Aluri, Scott Waldron, Karyn Schmidt, Maja M. Janas, Elena Castellanos-Rizaldos, Xiumin Liu, Michael Arciprete, Diane Ramsden, Jing Li, Vasant Jadhav, Robin McDougall, Christopher R. Brown, Bahru A. Habtemariam, Dale C. Guenther, Gabriel J. Robbie, Saket Agarwal, Muthiah Manoharan, Akshay Vaishnaw, Ivan Zlatev, Jeffrey Kurz, Jayaprakash K. Nair, Martin Maier, Saeho Chong, Sagar Agarwal, Christopher S. Theile, Steven Liou, Muthusamy Jayaraman, Varun Goel, Kevin Fitzgerald, Christopher MacLauchlin, Klaus Charisse, Joseph A Cichocki, Ju Liu, Yuanxin Xu, Peter F Smith, Jing-Tao Wu, Xuemei Zhang, Yongli Gu
المصدر: Drug Metabolism and Disposition. 50:781-797
مصطلحات موضوعية: Pharmacology, Small interfering RNA, Pharmacokinetics, Chemistry, In vivo, Pharmacodynamics, Pharmaceutical Science, Gene silencing, Distribution (pharmacology), PK/PD models, ADME
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::fa4ae67a6f9cc6256cba922321905899Test
https://doi.org/10.1124/dmd.121.000428Test -
4
المؤلفون: Li-Hua Guan, Qianfan Wang, Jing Li, Carrie Rocca, Valerie A. Clausen, Saeho Chong, Chris Tran, Yuanxin Xu, Guodong Zhang, Michael Arciprete, Ju Liu, Diana Najarian, Jing-Tao Wu, Xuemei Zhang, Peter F Smith
المصدر: Drug Metabolism and Disposition. 49:572-580
مصطلحات موضوعية: Pharmacology, biology, Chemistry, Pharmaceutical Science, Cytochrome P450, Isozyme, Excretion, Pharmacokinetics, biology.protein, Distribution (pharmacology), Active metabolite, Drug metabolism, ADME
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::845f7b4ca8072422f3e99326db273257Test
https://doi.org/10.1124/dmd.121.000381Test -
5
المؤلفون: Yesseinia I. Anglero-Rodriguez, Florian A. Lempp, James McIninch, Mark K. Schlegel, Christopher R. Brown, Donald J. Foster, Adam B. Castoreno, Tuyen Nguyen, Megha Subramanian, Martin Montiel-Ruiz, Hannah Kaiser, Anna Sahakyan, Roberto Spreafico, Svetlana Shulga Morskaya, Joseph D. Barry, Daniel Berman, Stephanie Lefebvre, Anne Kasper, Timothy Racie, Diann Weddle, Melissa Mobley, Arlin Rogers, Joseph Dybowski, Saeho Chong, Jayaprakash Nair, Amy Simon, Kevin Sloan, Seungmin Hwang, Herbert W. Virgin, Kevin Fitzgerald, Martin A. Maier, Gregory Hinkle, Christy M. Hebner, Akin Akinc, Vasant Jadhav
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1fd2ebe031d135cd9e0bfc23cecf5156Test
https://doi.org/10.1101/2022.03.20.485044Test -
6
المؤلفون: Shannon Gutierrez, Yuanxin Xu, Gabriel J. Robbie, Carrie Rocca, Samantha Chigas, James Butler, Saeho Chong, Yongli Gu, Sean Dennin, Joohwan Kim, Kirk Brown, Diana Najarian, Klaus Charisse
المصدر: Bioanalysis. 11:1927-1939
مصطلحات موضوعية: 0303 health sciences, Small interfering RNA, Oligonucleotide, Chemistry, 010401 analytical chemistry, Clinical Biochemistry, Ultrafiltration, Electrophoretic Mobility Shift Assay, Blood Proteins, General Medicine, Plasma protein binding, 01 natural sciences, 0104 chemical sciences, Analytical Chemistry, stomatognathic diseases, 03 medical and health sciences, Medical Laboratory Technology, Biochemistry, RNA interference, Antisense oligonucleotides, Electrophoretic mobility shift assay, RNA, Small Interfering, General Pharmacology, Toxicology and Pharmaceutics, Protein Binding, 030304 developmental biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12b7581bfeec025b29eef6b77852f50aTest
https://doi.org/10.4155/bio-2019-0151Test -
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المؤلفون: Maja M. Janas, Saeho Chong, Mark K Schlegel, Jason Gilbert, Saket Agarwal, Vasant Jadhav, Dale Gunther, Michelle Jung, Mark Keating, Kelly Wassarman, Shigeo Matsuda, Arlin Rogers, Yongfeng Jiang, Lei Johnson, Elena Castellanos-Rizaldos, Jessica E. Sutherland, Scott Lentini, Urjana Poreci, Klaus Charisse, Jing Li, Anne Kasper, Yesseinia Anglero-Rodriguez, Jeff Rollins, Jing-Tao Wu, Alex Kelin, Sarah Le Blanc Sarah Le Blanc, Diana Cha, Martin E. Maier, Adam Castoreno, Samantha Chigas, Tuyen Nguyen, Muthiah Manoharan, Wendell P Davis, Haiyan Peng, Jayaprakash K. Nair, John Petrulis, Christopher S. Theile, Tyler Chickering, Ivan Zlatev, Tim Racie, Kirk Brown, Christopher R. Brown, Stuart Milstein, Jessica Bombardier, Melissa Mobley, Jeffrey Allen, Raj Maganti, Donald Foster, Kevin Fitzgerald, Jeffrey Kurz, Lauren Blair Woods, Robin McDougall
مصطلحات موضوعية: Chemistry, Conjugate, RNAi Therapeutics, Cell biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::1b912cc876215cb4611322852009dc8fTest
https://doi.org/10.21203/rs.3.rs-946835/v1Test -
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المؤلفون: Kirk M. Brown, Jayaprakash K. Nair, Maja M. Janas, Yesseinia I. Anglero-Rodriguez, Lan T. H. Dang, Haiyan Peng, Christopher S. Theile, Elena Castellanos-Rizaldos, Christopher Brown, Donald Foster, Jeffrey Kurz, Jeffrey Allen, Rajanikanth Maganti, Jing Li, Shigeo Matsuda, Matthew Stricos, Tyler Chickering, Michelle Jung, Kelly Wassarman, Jeff Rollins, Lauren Woods, Alex Kelin, Dale C. Guenther, Melissa W. Mobley, John Petrulis, Robin McDougall, Timothy Racie, Jessica Bombardier, Diana Cha, Saket Agarwal, Lei Johnson, Yongfeng Jiang, Scott Lentini, Jason Gilbert, Tuyen Nguyen, Samantha Chigas, Sarah LeBlanc, Urjana Poreci, Anne Kasper, Arlin B. Rogers, Saeho Chong, Wendell Davis, Jessica E. Sutherland, Adam Castoreno, Stuart Milstein, Mark K. Schlegel, Ivan Zlatev, Klaus Charisse, Mark Keating, Muthiah Manoharan, Kevin Fitzgerald, Jing-Tao Wu, Martin A. Maier, Vasant Jadhav
المصدر: Nature biotechnology. 40(10)
مصطلحات موضوعية: Primates, Amyloid beta-Protein Precursor, Mice, RNAi Therapeutics, Biomedical Engineering, Molecular Medicine, Animals, Bioengineering, RNA Interference, RNA, Small Interfering, Applied Microbiology and Biotechnology, Biotechnology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a036125a57dba90192959ce807480ec6Test
https://pubmed.ncbi.nlm.nih.gov/35654979Test -
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المؤلفون: Robin, McDougall, Diane, Ramsden, Sagar, Agarwal, Saket, Agarwal, Krishna, Aluri, Michael, Arciprete, Christopher, Brown, Elena, Castellanos-Rizaldos, Klaus, Charisse, Saeho, Chong, Joseph, Cichocki, Kevin, Fitzgerald, Varun, Goel, Yongli, Gu, Dale, Guenther, Bahru, Habtemariam, Vasant, Jadhav, Maja, Janas, Muthusamy, Jayaraman, Jeffrey, Kurz, Jing, Li, Ju, Liu, Xiumin, Liu, Steven, Liou, Chris, Maclauchlin, Martin, Maier, Muthiah, Manoharan, Jayaprakash K, Nair, Gabriel, Robbie, Karyn, Schmidt, Peter, Smith, Christopher, Theile, Akshay, Vaishnaw, Scott, Waldron, Yuanxin, Xu, Xuemei, Zhang, Ivan, Zlatev, Jing-Tao, Wu
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 50(6)
مصطلحات موضوعية: Acetylgalactosamine, Hepatocytes, Humans, Asialoglycoprotein Receptor, RNA, Small Interfering, Porphyrias, Hepatic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::1ee09492e0ec47356243e1bb6d5c3b2cTest
https://pubmed.ncbi.nlm.nih.gov/34154993Test -
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المؤلفون: Valerie A. Clausen, Brad Zerler, Jim Jiang, Jing-Tao Wu, Krishna Aluri, Joohwan Kim, Diane Ramsden, Sajida Iqbal, Yongli Gu, Saeho Chong, Sean Dennin
المصدر: Drug Metabolism and Disposition. 47:1183-1194
مصطلحات موضوعية: Small interfering RNA, Acetylgalactosamine, Oligonucleotides, Pharmaceutical Science, Pharmacology, Models, Biological, Inhibitory Concentration 50, Cytochrome P-450 Enzyme System, Cytochrome P-450 Enzyme Inhibitors, Humans, Medicine, Computer Simulation, Drug Interactions, RNA, Small Interfering, Cells, Cultured, Enzyme Assays, Cytochrome P-450 Enzyme Inducers, Mechanism (biology), Oligonucleotide, business.industry, Membrane Transport Proteins, RNA, Transporter, Small molecule, Recombinant Proteins, In vitro, Hepatocytes, Target protein, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4a78d55fd803e90138bc24c2878200Test
https://doi.org/10.1124/dmd.119.087098Test