المؤلفون: John H. Riley, Ian Naya, Neil Barnes, Lee Tombs, Ana R. Sousa, Bernardino Alcázar Navarrete, Sadhana Patel, Gregory J. Feldman, David A. Lipson, Chris Compton

المساهمون: [Feldman, Gregory J.] S Carolina Pharmaceut Res, Spartanburg, SC 29303 USA, [Sousa, Ana R.] GlaxoSmithKline, Resp Res & Dev, Stockley Pk West, Uxbridge, Middx, England, [Lipson, David A.] GlaxoSmithKline, Resp Res & Dev, King Of Prussia, PA USA, [Lipson, David A.] Univ Penn, Perelman Sch Med, Philadelphia, PA 19104 USA, [Tombs, Lee] Precise Approach Ltd, Birmingham, W Midlands, England, [Barnes, Neil] GlaxoSmithKline, Global Resp Franchise, Brentford, Middx, England, [Patel, Sadhana] GlaxoSmithKline, Global Resp Franchise, Brentford, Middx, England, [Compton, Chris] GlaxoSmithKline, Global Resp Franchise, Brentford, Middx, England, [Riley, John H.] GlaxoSmithKline, GlaxoSmithKline Med Res Ctr, Resp Therapy Area Unit, Stevenage, Herts, England, [Naya, Ian] GlaxoSmithKline, Resp Med, Brentford, Middx, England, [Alcazar Navarrete, Bernardino] Hosp Alta Resoluc Loja, Neumol, Granada, Spain, GlaxoSmithKline

المصدر: Advances in Therapy

مصطلحات موضوعية: Male, Quinuclidines, Respimat, Long-acting β2-agonist, law.invention, Pulmonary Disease, Chronic Obstructive, chemistry.chemical_compound, 0302 clinical medicine, Randomized controlled trial, law, Forced Expiratory Volume, Medicine, Pharmacology (medical), Vilanterol, 030212 general & internal medicine, Original Research, education.field_of_study, COPD, Cross-Over Studies, Olodaterol, LAMA, Double-blind, General Medicine, Middle Aged, Dry-powder inhaler, Bronchodilator Agents, Drug Combinations, Treatment Outcome, Anesthesia, Combination, Long-acting beta 2-agonist, Female, Bronchodilation, Safety, Moderate, Population, LABA, Chlorobenzenes, 03 medical and health sciences, Bronchodilators, Double-Blind Method, Administration, Inhalation, Humans, Umeclidinium, Tiotropium Bromide, education, Benzyl Alcohols, Dynamic hyperinflation, Aged, business.industry, Nebulizers and Vaporizers, Tiotropium, medicine.disease, Confidence interval, Benzoxazines, Long-acting muscarinic antagonist, 030228 respiratory system, chemistry, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfa4d2adec229bf9ad2d05d732898175Test
https://doi.org/10.1007/s12325-017-0626-4Test

المؤلفون: Gabriele Dorn, Sadhana Patel, Glen Wotherspoon, Maja Hemmings-mieszczak, Pam Ganju William Wishart

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://nar.oxfordjournals.org/content/32/5/e49.full.pdfTest.

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.535.9067Test; http://nar.oxfordjournals.org/content/32/5/e49.full.pdfTest

الإتاحة: http://nar.oxfordjournals.org/content/32/5/e49.full.pdfTest

المؤلفون: Jane Barclay, Sadhana Patel, Gabriele Dorn, Glen Wotherspoon, Sarah Moffatt, Louise Eunson, Pam Ganju

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://www.jneurosci.org/content/22/18/8139.full.pdfTest.

وصف الملف: application/pdf

العلاقة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.328.9388Test; http://www.jneurosci.org/content/22/18/8139.full.pdfTest

الإتاحة: http://www.jneurosci.org/content/22/18/8139.full.pdfTest

المؤلفون: B. Alcazar Navarrete, Lee Tombs, Ana R. Sousa, David A. Lipson, Ian Naya, Chris Compton, Gregory Feldman, Sadhana Patel

المصدر: Pharmacotherapies for COPD.

مصطلحات موضوعية: medicine.medical_specialty, COPD, education.field_of_study, Vital capacity, Respimat, business.industry, Olodaterol, Population, medicine.disease, Crossover study, chemistry.chemical_compound, chemistry, Internal medicine, medicine, Clinical endpoint, Physical therapy, Vilanterol, business, education

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::a76edf414e3141b4a882d984ccded418Test
https://doi.org/10.1136/thoraxjnl-2017-210983.417Test

المؤلفون: Andrew Charlton, Stephen J. Medhurst, Laura J. Chambers, Livermore David, Brian Peter Slingsby, Andy Billinton, Lee William Page, Anton D. Michel, Daryl S. Walter, Jon Graham Anthony Steadman, Shilina Roman, Sadhana Patel, Elena Fonfria, Robert Gleave, Stefan Senger, Katharine Laura Collis, Andrew P. Moses, Sue D. Collins, Muna H. Abdi, Paul John Beswick, Clarisse L. Lejeune, David Kenneth Dean, Alexander J. Stevens

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:5080-5084

مصطلحات موضوعية: Models, Molecular, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Amide, Drug Discovery, Purinergic P2 Receptor Antagonists, medicine, Structure–activity relationship, Receptor, Molecular Biology, Drug discovery, Organic Chemistry, Antagonist, Receptor antagonist, Amides, Pyrrolidonecarboxylic Acid, chemistry, Molecular Medicine, Receptors, Purinergic P2X7, Pyroglutamic acid

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3ff37009bb76b9bfd50c27c623c06dTest
https://doi.org/10.1016/j.bmcl.2010.07.033Test

المؤلفون: Andy Billinton, Sue Roomans, Stefan Senger, Anton D. Michel, Stephen J. Medhurst, Robert Gleave, Daryl S. Walter, Elena Fonfria, Laura J. Chambers, Andrew P. Moses, Shilina Roman, David Kenneth Dean, Alexander J. Stevens, Paul John Beswick, Sadhana Patel

المصدر: Bioorganic & Medicinal Chemistry Letters. 20:4653-4656

مصطلحات موضوعية: Purinergic P2X Receptor Antagonists, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Analgesic, Administration, Oral, Pain, Pharmaceutical Science, Carboxamide, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Acetamides, Drug Discovery, medicine, Animals, Humans, Molecular Biology, Organic Chemistry, Antagonist, In vitro, Rats, Disease Models, Animal, chemistry, Hyperalgesia, Pyrazoles, Molecular Medicine, Receptors, Purinergic P2X7, medicine.symptom, Lead compound, Acetamide

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c05399c19e1a56ae550e1d9ced9f9a3aTest
https://doi.org/10.1016/j.bmcl.2010.05.107Test

المؤلفون: Adrian Hall, Susan H. Brown, Sadhana Patel, Andy Billinton, Gerard Martin Paul Giblin, Alan Naylor, Tiziana Scoccitti, David N. Hurst, Paul Goldsmith, Anita Chowdhury, Pamela J. Theobald

المصدر: Bioorganic & Medicinal Chemistry Letters. 18:2684-2690

مصطلحات موضوعية: Models, Molecular, Indoles, Molecular model, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Computational biology, Scaffold hopping, Biochemistry, Structure-Activity Relationship, In vivo, Drug Discovery, Animals, Humans, Receptors, Prostaglandin E, Receptor, Molecular Biology, Indole test, Molecular Structure, Chemistry, Organic Chemistry, Hydrogen Bonding, Inflammatory pain, Receptors, Prostaglandin E, EP1 Subtype, Rats, Thiazoles, Microsomes, Liver, Molecular Medicine

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f466feef99e2b2d9ba9ec68ab4f3aa5eTest
https://doi.org/10.1016/j.bmcl.2008.03.018Test

المؤلفون: Alyson Fox, Stuart Bevan, Pam Ganju, Jane Barclay, Jakir Hussain Ullah, Anna K. Clark, Marzia Malcangio, Janet Winter, Chuanzheng Song, Frank Buxton, Sadhana Patel, Clive Gentry, Glen Wotherspoon

المصدر: Pain. 130:225-234

مصطلحات موضوعية: Male, Pharmacology, Gene Expression Regulation, Enzymologic, Sciatica, medicine, Animals, RNA, Messenger, Rats, Wistar, Ligation, Oligonucleotide Array Sequence Analysis, Cathepsin S, CATS, business.industry, Macrophages, Nociceptors, Nerve injury, Cathepsins, Sciatic Nerve, Sensory neuron, Rats, Cysteine Endopeptidases, Disease Models, Animal, Anesthesiology and Pain Medicine, Allodynia, medicine.anatomical_structure, Nociception, Neurology, Hyperalgesia, Anesthesia, Chronic Disease, Peripheral nerve injury, Neurology (clinical), medicine.symptom, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135ee297597a9ac310f09e5ca90e950bTest
https://doi.org/10.1016/j.pain.2006.11.017Test

المؤلفون: Stuart Bevan, Alyson Fox, Adam Kesingland, Clive Gentry, Sadhana Patel

المصدر: Pain. 105:355-362

مصطلحات موضوعية: Male, Pain Threshold, Cyclohexanecarboxylic Acids, Gabapentin, Guinea Pigs, Analgesic, Oxcarbazepine, Acetates, Pharmacology, Lamotrigine, Pressure, medicine, Animals, Amines, Rats, Wistar, gamma-Aminobutyric Acid, Triazines, business.industry, Carbamazepine, Sciatic Nerve, Rats, Anesthesiology and Pain Medicine, Allodynia, Neurology, Hyperalgesia, Touch, Neuropathic pain, Neuralgia, Wounds and Injuries, Anticonvulsants, Neurology (clinical), medicine.symptom, business, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116440ea3d0fc48fb6095c8e9c9c6eb9Test
https://doi.org/10.1016/s0304-3959Test(03)00253-7

المؤلفون: Stephen J. Medhurst, Sadhana Patel, Peter McIntyre, Mohanjit Panesar, Katharine Walker, Alyson Fox, Laszlo Urban

المصدر: Journal of Pharmacology and Experimental Therapeutics. 304:56-62

مصطلحات موضوعية: Male, Receptors, Drug, Guinea Pigs, TRPV1, Pharmacology, Guinea pig, Mice, chemistry.chemical_compound, medicine, Animals, Rats, Wistar, Inflammation, Dose-Response Relationship, Drug, Antagonist, Peripheral Nervous System Diseases, Sciatic Nerve, Rats, Mice, Inbred C57BL, Carbamazepine, chemistry, Hyperalgesia, Capsaicin, Anesthesia, Neuropathic pain, Molecular Medicine, Anticonvulsants, Sciatic nerve, medicine.symptom, Capsazepine, Algorithms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c3ead2f110926964f07a1e17f30733Test
https://doi.org/10.1124/jpet.102.042010Test