المؤلفون: Sabina Ziemian, Norbert Löwa, Olaf Kosch, Daniel Bajj, Frank Wiekhorst, Gunnar Schütz

المصدر: Nanomaterials, Vol 8, Iss 4, p 180 (2018)

مصطلحات موضوعية: magnetic particle imaging (MPI), magnetic particle spectroscopy (MPS), iron oxide tracer, superparamagnetic nanoparticles, Chemistry, QD1-999

وصف الملف: electronic resource

العلاقة: http://www.mdpi.com/2079-4991/8/4/180Test; https://doaj.org/toc/2079-4991Test

الوصول الحر: https://doaj.org/article/94eeb311069e40d788b5c3e09fa741d5Test

المؤلفون: Daniel Scotcher (7440011), Nicola Melillo (11161053), Sirisha Tadimalla (2219440), Adam S. Darwich (11161056), Sabina Ziemian (11161059), Kayode Ogungbenro (11161062), Gunnar Schütz (11161065), Steven Sourbron (9042614), Aleksandra Galetin (3846784)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Physiology, Pharmacology, Biotechnology, Inorganic Chemistry, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, gadoxetate liver data, DCE, PBPK modeling applications, CV, MRP, MRI, OATP, Imaging Biomarker Gadoxetate, PBPK model, liver-imaging data, organic-anion-transporting polypept., refining PBPK transporter IVIVE, Transporter-Mediated Hepatic Dispos., 1B, gadoxetate PBPK model, hepatocyte, uptake, gadoxetate hepatic tDDI, vivo, multidrug resistance-associated pro., PBPK model refinement

العلاقة: https://figshare.com/articles/journal_contribution/Physiologically_Based_Pharmacokinetic_Modeling_of_Transporter-Mediated_Hepatic_Disposition_of_Imaging_Biomarker_Gadoxetate_in_Rats/15025482Test

الإتاحة: https://doi.org/10.1021/acs.molpharmaceut.1c00206.s001Test

المؤلفون: Sirisha Tadimalla, Daniel Scotcher, Adam S. Darwich, Steven Sourbron, Kayode Ogungbenro, Gunnar Schütz, Sabina Ziemian, Nicola Melillo, Aleksandra Galetin

المصدر: Molecular Pharmaceutics
Mol. Pharmaceutics

مصطلحات موضوعية: Gadolinium DTPA, Male, Physiologically based pharmacokinetic modelling, Imaging biomarker, quantitative translation, physiologically based pharmacokinetic model, Biological Transport, Active, Contrast Media, Organic Anion Transporters, Pharmaceutical Science, drug transporters, Pharmacology, Article, Pharmacokinetics, In vivo, Drug Discovery, medicine, Animals, imaging biomarker, Drug Interactions, drug−drug interactions, Cells, Cultured, medicine.diagnostic_test, Chemistry, Multidrug resistance-associated protein 2, Transporter, Magnetic resonance imaging, Magnetic Resonance Imaging, Rats, medicine.anatomical_structure, Liver, gadoxetate, Hepatocyte, Models, Animal, Hepatocytes, Molecular Medicine, hepatobiliary excretion, Rifampin, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8273f7c9644e0d3b1f1acd044719deeeTest
https://doi.org/10.1021/acs.molpharmaceut.1c00206Test

المؤلفون: Gregor Jost, Catherine D. G. Hines, Sabina Ziemian, Gunnar Schütz, Claudia Green, Steven Sourbron

المصدر: Nmr in Biomedicine
NMR in Biomedicine

مصطلحات موضوعية: Gadolinium DTPA, bile, blood, Gadolinium, chemistry.chemical_element, Urine, Chronic liver disease, 030218 nuclear medicine & medical imaging, Excretion, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, medicine, Animals, Bile, Radiology, Nuclear Medicine and imaging, Spectroscopy, Research Articles, DCE‐MRI, business.industry, liver/hepatocytes, Biological Transport, medicine.disease, Magnetic Resonance Imaging, urine, 3. Good health, Kinetics, Magnetic Fields, chemistry, gadoxetate, Liver, relaxivity, Molecular Medicine, Mrp2‐KO rat, Female, Liver function, Liver cancer, Nuclear medicine, business, 030217 neurology & neurosurgery, Ex vivo, Research Article

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b63524cbc77cc5c541a7754a4a4d0bdTest
http://europepmc.org/articles/PMC7757196Test

المؤلفون: Gunnar Schütz, Lars E. Olsson, Irvin Teh, Steven Sourbron, Andor Veltien, Jürgen E. Schneider, Michael Gottschalk, Iina Laitinen, William Lloyd, James P B O'Connor, Denise Steinmann, Hans Paul Juretschke, Catherine D. G. Hines, Sabina Ziemian, Xiaomeng Zhang, Simon Campbell, Sirisha Tadimalla, Claudia Green, Katja Hassemer, Kashmira Pindoria, John C. Waterton, Yanping Luo, Paul D. Hockings, Irma Mahmutovic Persson, Michael V. Haase, Klaus Strobel, Sascha Koehler

المصدر: Magnetic Resonance Imaging
Magnetic Resonance Imaging, 59, 121-129
Magnetic Resonance Imaging, 59, pp. 121-129
Waterton, J C, Hines, C D G, Hockings, P D, Laitinen, I, Ziemian, S, Campbell, S, Gottschalk, M, Green, C, Haase, M, Hassemer, K, Juretschke, H P, Koehler, S, Lloyd, W, Luo, Y, Mahmutovic Persson, I, O'Connor, J P B, Olsson, L E, Pindoria, K, Schneider, J E, Sourbron, S, Steinmann, D, Strobel, K, Tadimalla, S, Teh, I, Veltien, A, Zhang, X & Schütz, G 2019, ' Repeatability and reproducibility of longitudinal relaxation rate in 12 small-animal MRI systems ', Magnetic Resonance Imaging, vol. 59, pp. 121-129 . https://doi.org/10.1016/j.mri.2019.03.008Test

مصطلحات موضوعية: ResearchInstitutes_Networks_Beacons/MICRA, Materials science, Phantom, Biomedical Engineering, Biophysics, Saturation recovery, Longitudinal Relaxation Rate, Imaging phantom, Article, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, Mice, All institutes and research themes of the Radboud University Medical Center, 0302 clinical medicine, Nickel, Small animal, Urological cancers Radboud Institute for Molecular Life Sciences [Radboudumc 15], medicine, Image Processing, Computer-Assisted, Water proton, Animals, Radiology, Nuclear Medicine and imaging, Computer Simulation, Hardware stability, Reproducibility, medicine.diagnostic_test, Phantoms, Imaging, Sepharose, Reproducibility of Results, Water, Relaxation time, Magnetic resonance imaging, Biomarker, Repeatability, Magnetic Resonance Imaging, Rats, Oxygen, Error propagation, Manchester Institute for Collaborative Research on Ageing, Regression Analysis, Protons, 030217 neurology & neurosurgery, Biomarkers, MRI, Biomedical engineering

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19081a1f799d0cd7ca9359bc97b8ba33Test
https://europepmc.org/articles/PMC6477178Test/

المؤلفون: Kayode Ogungbenro, Daniel Scotcher, Adam S. Darwich, Sabina Ziemian, Steven Sourbron, Aleksandra Galetin, Gunnar Schütz, Sirisha Tadimalla

المصدر: Drug Metabolism and Pharmacokinetics. 35:S96

مصطلحات موضوعية: Pharmacology, Physiologically based pharmacokinetic modelling, Imaging biomarker, Chemistry, Pharmaceutical Science, Pharmacology (medical), Transporter, Hepatic disposition

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::9ffbf7595145e7d9e1bc956b1017f1dbTest
https://doi.org/10.1016/j.dmpk.2020.04.244Test

المؤلفون: Daniel N. F. Bajj, Norbert Löwa, Gunnar Schütz, Frank Wiekhorst, Sabina Ziemian, Olaf Kosch

المصدر: Nanomaterials
Nanomaterials; Volume 8; Issue 4; Pages: 180
Nanomaterials, Vol 8, Iss 4, p 180 (2018)

مصطلحات موضوعية: Materials science, General Chemical Engineering, Analytical chemistry, Iron oxide, 02 engineering and technology, Magnetic particle inspection, magnetic particle imaging (MPI), Article, 030218 nuclear medicine & medical imaging, lcsh:Chemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Magnetic particle imaging, General Materials Science, Image resolution, magnetic particle spectroscopy (MPS), chemistry.chemical_classification, iron oxide tracer, Polymer, 021001 nanoscience & nanotechnology, superparamagnetic nanoparticles, chemistry, lcsh:QD1-999, Particle, 0210 nano-technology, Ethylene glycol, Iron oxide nanoparticles

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf66e3cf02ca54367908b2c11eedec8eTest
http://europepmc.org/articles/PMC5923510Test

المؤلفون: Andreas Baudy, Manishkumar Patel, Paul D. Hockings, Daniel Scotcher, John C. Waterton, Aleksandra Galetin, J. Gerry Kenna, Gunnar Schuetz, Steven Sourbron, Catherine D. G. Hines, Sabina Ziemian

المصدر: Drug-Induced Liver Toxicity
Methods in Pharmacology and Toxicology ISBN: 9781493976768
Kenna, J G, Waterton, J C, Baudy, A, Galetin, A, Hines, C D G, Hockings, P, Patel, M, Scotcher, D, Sourbron, S, Ziemian, S & Schuetz, G 2018, Noninvasive preclinical and clinical imaging of liver transporter function relevant to drug-induced liver injury . in Drug-Induced Liver Toxicity . Methods in Pharmacology and Toxicology, no. 9781493976768, Humana Press, Inc, New York, NY, pp. 627-651 . https://doi.org/10.1007/978-1-4939-7677-5_30Test
Methods in Pharmacology and Toxicology
Methods in Pharmacology and Toxicology-Drug-Induced Liver Toxicity

مصطلحات موضوعية: Drug, Drug-induced liver injury, Gadoxetate, media_common.quotation_subject, Hepatobiliary transporters, Causality assessment, Pharmacology, 030226 pharmacology & pharmacy, 030218 nuclear medicine & medical imaging, Drug labelling, Pharmacology, Toxicology and Pharmaceutics(all), 03 medical and health sciences, 0302 clinical medicine, Medicine, Drug-drug interactions, Pharmacology (medical), Clinical imaging, media_common, Liver injury, business.industry, Hepatotoxicity, Transporter, medicine.disease, Bile Salt Export Pump, 3. Good health, Molecular Medicine, Bile salt export pump, business, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9d95eadbc9aaa8385974439dd215e6Test

المؤلفون: Daniel Scotcher, Nicola Melillo, Sirisha Tadimalla, Adam Darwich, Sabina Ziemian, Kayode Ogungbenro, Gunnar Schütz, Sourbron, Steven P., Aleksandra Galetin

المصدر: University of Manchester-PURE

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::023c23d469c7b05c79a797c09689cca4Test
https://research.manchester.ac.uk/en/publications/59fd2e6c-d010-4330-b41a-88f6eab1366aTest