المؤلفون: Andreas E. Moor, Nina Frey, Ying K. Tam, Denis V Victorov, Costanza Borrelli, Kevin Holden, Melissa K Dennis, Martin Jinek, Dominik Witzigmann, Rurika Oka, Susanne Kreutzer, Lukas Villiger, Gerald Schwank, Martina Hruzova, Lucas Kissling, Norbert Pardi, Daniela Lenggenhager, Markus Stoffel, Ruben van Boxtel, Zacharias Kontarakis, Beat Thöny, Sean C. Semple, Anastasia P. Kadina, John A. Walker, Johannes Häberle, Sabina Egli, Tanja Rothgangl, Noëlle Bakker, Martin Pacesa, Weihong Qi, Paulo J.C. Lin, Drew Weissman

المساهمون: Ophthalmology, Graduate School, ACS - Microcirculation, University of Zurich, Semple, Sean C, Schwank, Gerald

المصدر: Nature Biotechnology, 39 (8)
Nature Biotechnology
Nature biotechnology, 39(August 2021). Nature Publishing Group

مصطلحات موضوعية: Male, 10050 Institute of Pharmacology and Toxicology, Applied Microbiology and Biotechnology, PCSK9, Mice, Gene Editing, biology, Genetic engineering, Targeted gene repair, Liver, LDL cholesterol, 1305 Biotechnology, Molecular Medicine, Proprotein Convertase 9, RNA, Guide, Kinetoplastida, Biotechnology, Adult, medicine.medical_specialty, Biomedical Engineering, 2204 Biomedical Engineering, 610 Medicine & health, 10071 Functional Genomics Center Zurich, Bioengineering, Article, Base editing, Abes, Immune system, In vivo, 10049 Institute of Pathology and Molecular Pathology, Internal medicine, 10019 Department of Biochemistry, medicine, Animals, 2402 Applied Microbiology and Biotechnology, Humans, Messenger RNA, 1502 Bioengineering, Adenine, Point mutation, Cholesterol, LDL, biology.organism_classification, Mice, Inbred C57BL, genomic DNA, Endocrinology, 10036 Medical Clinic, 1313 Molecular Medicine, Macaca, CRISPR-Cas Systems, Lipoprotein

وصف الملف: application/application/pdf; Rothgangl_NatBio_41587_2021_Article_933.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ae069a0668f90ce5cdbb49415cc632Test
https://doi.org/10.1038/s41587-021-00933-4Test

المؤلفون: Richard Plieninger, Martin Fussenegger, Adrian Bertschi, Tobias Strittmatter, Daniel Bojar, Sabina Egli, Mingqi Xie

المصدر: Biotechnology and Bioengineering. 118:2220-2233

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Glycosylation, Transgene, Regulator, Bioengineering, CHO Cells, Transfection, 01 natural sciences, Applied Microbiology and Biotechnology, 03 medical and health sciences, Cricetulus, Genes, Reporter, 010608 biotechnology, Animals, Humans, Gene Regulatory Networks, Inducer, Binding site, Transcription factor, Gene, Chemistry, Sugar Acids, Promoter, Paracoccus, Cell biology, Glucose, HEK293 Cells, 030104 developmental biology, Rituximab, Plasmids, Transcription Factors, Biotechnology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a05013bdffb93e3e7853c1ca10fc3dTest
https://doi.org/10.1002/bit.27730Test