المؤلفون: Brian S. J. Blagg, Michael A. Serwetnyk

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1446-1468 (2021)

مصطلحات موضوعية: MD, middle domain, Review, SUMO, small ubiquitin-like modifier, TPR2A, tetratricopeptide-containing repeat 2A, chemistry.chemical_compound, 0302 clinical medicine, Immunophilins, polycyclic compounds, General Pharmacology, Toxicology and Pharmaceutics, Natural products, 0303 health sciences, biology, Small molecules, HIF-1α, hypoxia-inducing factor-1α, HSQC, heteronuclear single quantum coherence, Geldanamycin, Hsp90, CTD, C-terminal domain, Radicicol, Cell biology, 030220 oncology & carcinogenesis, HOP, Hsp70‒Hsp90 organizing protein, SAHA, suberoylanilide hydroxamic acid, Protein folding, ATP, adenosine triphosphate, Cdc37, cell division cycle 37, RM1-950, Protein–protein interaction, 03 medical and health sciences, TROSY, transverse relaxation-optimized spectroscopy, Heat shock protein, SAR, structure–activity relationship, NTD, N-terminal domain, Heat shock, 030304 developmental biology, Disruptors, TRAP1, Hsp75tumor necrosis factor receptor associated protein 1, Hsp90, 90-kD heat shock protein, Her-2, human epidermal growth factor receptor-2, Aha1, activator of Hsp90 ATPase homologue 1, HIP, Hsp70-interaction protein, hERG, human ether-à-go-go-related gene, PPI, protein−protein interaction, ADP, adenosine diphosphate, chemistry, Grp94, 94-kD glucose-regulated protein, biology.protein, Protein−protein interactions, Therapeutics. Pharmacology, Peptidomimetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d551031a93c74226093f0f0844e22506Test
https://doi.org/10.1016/j.apsb.2020.11.015Test

المؤلفون: Lin Guo, Leah Gottlieb, Ronen Marmorstein, James Shorter

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Hsf1, heat-shock factor 1, Huntingtin, post-translational modification (PTM), HttQ44, 44 polyQ, DSS, disuccinimidyl suberate, cotranslational modification, SUMO, small ubiquitin-like modifier, Biochemistry, 6xHis, 6xhistidine, Exon, EGS, ethylene glycol bis(succinimidyl succinate, neurodegenerative disease, biophysics, Ac-HttQ25, N-terminally acetylated HttQ25, N-Terminal Acetyltransferase A, DLS, dynamic light scattering, Huntingtin Protein, Chemistry, HttQ25, 25 polyQ, t50, aggregation half-time, aggregation, Acetylation, Huntington disease, Cell biology, NAT, N-terminal acetyltransferase, N17, 17 N-terminal Htt residues, Acetyltransferase, Research Article, congenital, hereditary, and neonatal diseases and abnormalities, αSyn, α-synuclein, TEV, tobacco etch virus, Protein Aggregates, Huntington's disease, mental disorders, medicine, Humans, TEM, transmission electron microscopy, Molecular Biology, NatA, N-terminal acetylation, polyQ, poly-glutamine, (GS)4, four–Gly–Ser linker, Cell Biology, medicine.disease, Htt, Huntingtin, In vitro, nervous system diseases, HD, Huntington’s disease, nervous system, hNatA, humanNatA, Peptides, Protein Processing, Post-Translational, Function (biology)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f55b27d897db97de8c12174e9411adTest
http://europepmc.org/articles/PMC8640455Test

المؤلفون: Gustavo M. Silva, Nathan A. Snyder

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: translation, Ubiquitin C-Terminal Hydrolase, CYLD, conserved cylindromatosis, SUMO, small ubiquitin-like modifier, Biochemistry, MJD, Machado–Josephin domain, Deubiquitinating enzyme, TRAF6, tumor necrosis factor (TNF) receptor associated factor 6, RTU, redox control of translation by ubiquitin, USP, ubiquitin-specific protease, Ubiquitin, oxidative stress, Homeostasis, deubiquitination, BER, base excision repair, TNF, tumor necrosis factor, biology, Deubiquitinating Enzymes, Chemistry, OTU, ovarian tumor domain, Cell biology, AMSH, associated molecule with the SH3 domain of STAM, Mdm2, Polβ, DNA polymerase beta, Ubp, ubiquitin-binding protein, Oxidation-Reduction, Deubiquitination, Signal Transduction, TRAF2, tumor necrosis factor (TNF) receptor associated factor 2, PCNA, proliferating cell nuclear antigen, OTUB, varian tumor deubiquitinase, ubiquitin aldehyde binding, DUB, A20, tumor necrosis factor alpha–induced protein 3, MIC-CAP, microcephaly-capillary malformation, ROS, reactive oxygen species, ESCRT, endosomal sorting complexes required for transport, MDM2, Mouse double minute 2, ubiquitin, TGF-β, transforming growth factor beta, Endopeptidases, ATXN, ataxin, Integrated stress response, UPS, ubiquitin-proteasome system, Animals, Humans, redox signaling, Molecular Biology, enzymatic regulation, ISR, integrated stress response, BAP1, BRCA1-associated protein 1, JBC Reviews, Ubiquitination, WDR48, WD repeat domain 48, Tumor Necrosis Factor alpha-Induced Protein 3, Cell Biology, RPN11, regulatory particle non-ATPase 11, EGFR, epidermal growth factor receptor, CK2, casein kinase 2, QC, quality control, MINDY, motif interacting with Ub-containing novel DUB, FOXO4, forkhead box O4, Proteasome, DTT, dithiothreitol, NLS, nuclear localization signal, UCH, ubiquitin C-terminal hydrolase, biology.protein, RQC, ribosome-associated quality control, PTM, posttranslational modification, UIM, ubiquitin interacting motif, OTUD, ovarian tumor deubiquitinase, Reactive Oxygen Species, Protein Processing, Post-Translational, DUB, deubiquitinating enzyme or deubiquitinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c743630c2855f90492c29a0b696db4Test
http://europepmc.org/articles/PMC8424594Test

المؤلفون: Ulbricht, David, Pippel, Jan, Schultz, Stephan, Meier, René, Sträter, Norbert, Heiker, John T.

مصطلحات موضوعية: Abz, o-aminobenzoyl, AT, antithrombin III, Dnp, 2,4-dinitrophenyl, GAG, glycosaminoglycan, KLK7, kallikrein 7, Mca,(7-methoxycoumarin-4-yl)acetyl, Nva, norvaline, RCL, reactive centre loop, RP, reversed-phase, SI, stoichiometry of inhibition, SUMO, small ubiquitin-like modifier, TLS,Translation–Libration–Screw-rotation, ufh, unfractionated heparin, info:eu-repo/classification/ddc/572, ddc:572

الإتاحة: https://ul.qucosa.de/id/qucosa%3A33439Test
https://ul.qucosa.de/api/qucosa%3A33439/attachment/ATT-0Test/

المؤلفون: Qianqian Yang, Hailong Zhang, Nan Cui, Jinzhuo Dou, Xian Zhao, Jianxiu Yu, Ran Chen, Yanli Wang, Jian Huang, Yanmin Guo, Tianqi Liu

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 7, Pp 676-688 (2019)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, Original article, Cancer Research, PTM, post-translational modification, Ubiquitin-Protein Ligases, SUMO-1 Protein, Lysine, SFKs, Src family kinases, SUMO protein, SUMO, small ubiquitin-like modifier, lcsh:RC254-282, GST, glutathione S-transferase, CSK Tyrosine-Protein Kinase, 03 medical and health sciences, 0302 clinical medicine, Csk, C-terminal Src kinase, SH, Src homology, Neoplasms, PIAS, protein inhibitor of activated STAT, Cbp, Csk binding protein, Humans, Phosphorylation, biology, Kinase, Chemistry, Sumoylation, Hydrogen Peroxide, SENP1, sentrin-specific protease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Protein Inhibitors of Activated STAT, Cell biology, Ubiquitin ligase, src-Family Kinases, 030104 developmental biology, Tumor progression, 030220 oncology & carcinogenesis, Small Ubiquitin-Related Modifier Proteins, biology.protein, Ectopic expression, Protein Processing, Post-Translational, Tyrosine kinase, Molecular Chaperones, Protein Binding

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d69e4a54e43bfcd1e5a45f6668b3aceTest
http://www.sciencedirect.com/science/article/pii/S1476558619300673Test

المؤلفون: Elah Pick

المصدر: Redox Biology, Vol 37, Iss, Pp 101765-(2020)
Redox Biology

مصطلحات موضوعية: 0301 basic medicine, Rub1, Clinical Biochemistry, NEDD8, Neural precursor cell Expressed Developmentally Downregulated gene 8, Review Article, Mitochondrion, medicine.disease_cause, Biochemistry, NEDD8, WHB, winged-helix B, Respiratory electron transport chain, COP9 signalosome, 0302 clinical medicine, Saccharomycotina, Ub, ubiquitin, lcsh:QH301-705.5, lcsh:R5-920, biology, Ascomycota, Chemistry, UCH, ubiquitin carboxyl terminal hydrolase, CSN, COP9 signalosome, SR, substrate receptor, Mitochondria, Cell biology, Rub1, Related ub 1, HIF-α1, Hypoxia-inducible factor α-1, Ubl, ubiquitin-like, lcsh:Medicine (General), Pezizomycotina, Cullin-RING E3 ligase, Saccharomyces cerevisiae Proteins, ETC, electron transfer respiratory chain, PCNA, proliferating cell nuclear antigen, Saccharomyces cerevisiae, 03 medical and health sciences, ROS, reactive oxygen species, medicine, SUMO, Small Ubiquitin-like Modifier, PARP1, Poly ADP-Ribose Polymerase 1, Ubiquitins, ULP1, Ub Like Protease 1, Organic Chemistry, biology.organism_classification, mtDNA, mitochondrial DNA, Oxidative Stress, Taphrinomycotina, 030104 developmental biology, lcsh:Biology (General), CRLs, cullin-RING E3 ligases, NEDP1, 030217 neurology & neurosurgery, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26812203b39d79a81d23b55233a217a1Test
http://www.sciencedirect.com/science/article/pii/S2213231720309708Test

المؤلفون: Fielden, J, Ruggiano, A, Popović, M, Ramadan, K

المصدر: DNA Repair

مصطلحات موضوعية: WLM, Wss1p-like metalloproteases, PTM, post-translational modification, DNA Repair, ERCC1, excision repair cross-complementing gene 1, DNA-protein crosslinks, PARP, poly (ADP-ribose) Polymerase, SUMO, small ubiquitin-like modifier, DNA Adducts, HER2, human epidermal growth factor receptor 2, SPRTN protease, ACRC, acidic repeat containing, Cancer, SIM, SUMO-interacting motif, ss/ds DNA, single-stranded/double-stranded DNA, PIAS, protein inhibitor of activated STAT protein, MEFs, mouse embryonic fibroblasts, Top1/2-cc, topoisomerase 1/2 cleavage complex, Eukaryota, MRN complex, Mre11-Rad50-Nbs1 complex, DNA-Binding Proteins, Cross-Linking Reagents, DPCP, DNA-protein crosslink proteolysis, FA, formaldehyde, CPT, camptothecin, Post-translational modification, Saccharomyces cerevisiae Proteins, PCNA, proliferating cell nuclear antigen, UBC9, ubiquitin carrier protein 9, GCNA, germ cell nuclear antigen, Saccharomyces cerevisiae, Article, 5-aza-dC, 5-aza-2′-deoxycytidine, SHP, Src homology 2-containing Phosphatase, C. elegans, Caenorhabditis elegans, RJALS, Ruijs–Aalfs syndrome, UBZ, ubiquitin-binding zinc finger, NER, nucleotide excision repair, NSCLC, non-small cell lung cancer, STUbL, SUMO-targeted ubiquitin ligases, Genome stability, DNMT1, DNA methyltransferase 1, DPC, DNA-protein crosslink, Animals, Humans, DSB, double-strand break, TLS, translesion synthesis, CtIP, C-terminal-binding protein interacting protein, S. cerevisiae, Saccharomyces cerevisiae, IR, ionising radiation, MAFFT, multiple alignment using fast fourier transform, XPF, Xeroderma Pigmentosum group F-complementing protein, Wss1, weak suppressor of Smt3-1, ATM, ataxia-telangiectasia mutated, TDP1/2, tyrosyl-DNA phosphodiesterase 1/2, DNA, UV, ultraviolet, Ageing, SPRTN, SprT-like N-terminal domain, APC, anaphase promoting complex, Proteolysis, ETO, etoposide, HR, homologous recombination

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3e5438d87ad1b1061b50aef98e3fe56aTest
https://doi.org/10.1016/j.dnarep.2018.08.025Test

المؤلفون: Xiang Ren, Edward T.H. Yeh, Qi Su, Hongmei Wu, Xing Dang, Zhengcao Xing, Yitao Qi, Yuanyuan Qin, Xinyi Yang, Yan Liu, Xu Chen, Yuhong Zhang, Zhantao Bai, Yajie Shen, Yaya Wang

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: PIP2, phosphatidylinositol 4,5-bisphosphate, Calmodulin, medicine.medical_treatment, Amino Acid Motifs, Kv7, SUMO protein, Ubiquitin-Activating Enzymes, PE, phosphatidylethanolamine, SUMO, small ubiquitin-like modifier, Second Messenger Systems, Biochemistry, SENP2, sentrin/SUMO-specific protease 2, KCNQ3 Potassium Channel, Mice, chemistry.chemical_compound, PIP2, Seizures, SENP2, medicine, SUDEP, sudden unexplained death in epilepsy, Animals, KCNQ2 Potassium Channel, PA, phosphatidic acid, Molecular Biology, CaM, calmodulin, Protease, biology, co-IP, coimmunoprecipitation, AV, atrioventricular, Myocardium, Retigabine, retigabine, Brain, Sumoylation, Cell Biology, PS, phosphatidylserine, Mice, Mutant Strains, Potassium channel, Cell biology, Cysteine Endopeptidases, chemistry, Phosphatidylinositol 4,5-bisphosphate, Second messenger system, biology.protein, CaM1, Acetylcholine, Research Article, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d1b5a8c1830e7fd199c0497599c4e9Test
https://doi.org/10.1016/j.jbc.2021.101183Test

المؤلفون: Kiran Sankar Chatterjee, Ranabir Das

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Protein Folding, Protein family, Phenylalanine, Amino Acid Motifs, SUMO-1 Protein, SUMO protein, Molecular Dynamics Simulation, sulfur-aromatic interaction, SUMO, small ubiquitin-like modifier, Biochemistry, structure-function, Chromatin remodeling, RMSF, root mean square fluctuation, SIM, SUMO interacting motif, Structure-Activity Relationship, chemistry.chemical_compound, Methionine, Transcriptional regulation, Aromatic amino acids, Humans, Protein Interaction Domains and Motifs, Amino Acid Sequence, SUMO-interacting motif (SIM), Structural motif, CD, circular dichroism, Molecular Biology, PML, promyelocytic leukemia, UBL, ubiquitin-Like, Protein Stability, Chemistry, methionine-aromatic motifs, Sumoylation, Cell Biology, CSP, chemical shift perturbation, MD, molecular dynamics, Cell biology, DMS, dimethyl sulfide, Protein folding, Function (biology), Research Article

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1b655e7c1a008d3713168bb08b3c83Test
https://doi.org/10.1016/j.jbc.2021.100970Test

المؤلفون: Ran Chen, Yanli Wang, Jing Wang, Jinzhuo Dou, Jianxiu Yu, Nan Cui, Hailong Zhang, Rong Deng, Tianqi Liu, Jian Huang, Xian Zhao

المصدر: Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 12, Pp 961-971 (2017)
Neoplasia (New York, N.Y.)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Cancer Research, Original article, Protein Conformation, Lysine, SUMO protein, SFKs, Src family kinases, Biology, SUMO, small ubiquitin-like modifier, lcsh:RC254-282, GST, glutathione S-transferase, Cell Line, Focal adhesion, 03 medical and health sciences, Mice, SH, Src homology, Neoplasms, Animals, Humans, SENPs, SUMO-sentrin specific proteases, Phosphorylation, Tyrosine-protein kinase CSK, CDS, coding sequence, Sumoylation, IP, immunoprecipitation, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 030104 developmental biology, src-Family Kinases, Tumor progression, FAK, Focal adhesion kinase, Focal Adhesion Protein-Tyrosine Kinases, Mutation, Cancer research, Disease Progression, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c45910c7b9bc87563c80cef563ac0886Test
http://www.sciencedirect.com/science/article/pii/S1476558617303184Test