نتائج البحث - "STAT1, signal transducer and activator of transcription 1"

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 81-98 (2021)

مصطلحات موضوعية: 0301 basic medicine, H3K79, histone 3 lysine 79, RC799-869, TNF-α, tumor necrosis factor-α, SOCS1, suppressor of cytokine signaling 1, Mice, 0302 clinical medicine, DC, dendritic cell, PCR, polymerase chain reaction, FH, fulminant hepatitis, STAT1, signal transducer and activator of transcription 1, Original Research, Liver injury, TGF-β, transforming growth factor β, biology, Th1, T helper 1, Gastroenterology, Diseases of the digestive system. Gastroenterology, MDSC, myeloid-derived suppressive cell, Nitric oxide synthase, ChIP, chromatin immunoprecipitation, Leukemia, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, Female, Antibody, GM-CSF, granulocyte-macrophage colony-stimulating factor, Fulminant Hepatitis, PBS, phosphate-buffered saline, Treg, regulatory T cell, 03 medical and health sciences, Downregulation and upregulation, medicine, Animals, Humans, IFN, interferon, COX2, cyclooxygenase-2, Dot1L, disruptor of telomeric silencing-1-like, NO, nitric oxide, Hepatology, business.industry, Suppressor of cytokine signaling 1, CFSE, carboxyfluorescein diacetate succinimidyl ester, Myeloid-Derived Suppressor Cells, MNC, mononuclear cell, DOT1L, Histone-Lysine N-Methyltransferase, medicine.disease, IL, interleukin, Mice, Inbred C57BL, Inducible Nitric Oxide Synthase, 030104 developmental biology, HBV, hepatitis B virus, biology.protein, Cancer research, Myeloid-derived Suppressor Cell, BM, bone marrow, Benzimidazoles, business, Histone Methyltransferase Dot1L

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d82e014595687febdc00cc6e2d20a6aTest
https://pubmed.ncbi.nlm.nih.gov/33497867Test

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8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions

المؤلفون: Istvan Boldogh, Xueqing Ba

المصدر: Redox Biology, Vol 14, Iss, Pp 669-678 (2018)
Redox Biology

مصطلحات موضوعية: 0301 basic medicine, DNA Repair, 8-oxoG, 7, 8-dihydro-8-oxoguanine, Clinical Biochemistry, Review Article, Sp1, specificity protein1, AP-1, activator protein 1, Biochemistry, DNA Glycosylases, Epigenesis, Genetic, chemistry.chemical_compound, 0302 clinical medicine, BER, base excision repair, STAT1, signal transducer and activator of transcription 1, OGG1, lcsh:QH301-705.5, Gene expression regulation, lcsh:R5-920, DNA methylation, NF-kappa B, Epigenetic, OGG1, 8-oxoguanine DNA glycosylase 1, 030220 oncology & carcinogenesis, lcsh:Medicine (General), IIR, innate immune response, Guanine, DNA repair, DNA damage, TNFα, Tumor necrosis factor alpha, MBPs, methyl-CpG-binding proteins, Biology, NF-κB, Nuclear Factor kappa B, 03 medical and health sciences, ROS, reactive oxygen species, Animals, Humans, OGG1-BER, OGG1-initiated DNA base excision repair, Organic Chemistry, DNA, 8-Oxoguanine, Oxidative Stress, 030104 developmental biology, chemistry, lcsh:Biology (General), DNA glycosylase, (Me)C, methylation of cytosine, 8-oxoguanine, GC-content, DNA Damage

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1dc705f99a651855d76916d093c4dafTest
http://www.sciencedirect.com/science/article/pii/S2213231717305311Test

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Feature Selection Methods for Protein Biomarker Discovery from Proteomics or Multiomics Data

المؤلفون: Qiang Gao, Zhiao Shi, Bing Zhang, Bo Wen

المصدر: Molecular & Cellular Proteomics : MCP

مصطلحات موضوعية: Proteomics, SPCA, supervised principal component analysis, Computer science, LR, logistic regression, Biochemistry, Mass Spectrometry, SMC4, structural maintenance of chromosome subunit 4, Analytical Chemistry, kNN, k-nearest neighbor, Biomarker discovery, STAT1, signal transducer and activator of transcription 1, 0303 health sciences, LASSO, least absolute shrinkage and selection operator, GBM, gradient boosting machine, Liver Neoplasms, 030302 biochemistry & molecular biology, MSI, microsatellite instability, Prognosis, MSS, microsatellite stable, Neoplasm Proteins, RF, random forests, Feature (computer vision), RSEM, RNA-seq by expectation maximization, iBAQ, intensity-based absolute quantification, Colorectal Neoplasms, Algorithms, Carcinoma, Hepatocellular, Feature selection, Computational biology, 03 medical and health sciences, FPKM, fragments per kilobase of transcript per million mapped reads, Biomarkers, Tumor, AUROC, area under the receiver operating characteristic curve, Humans, Lysophosphatidylcholine acyltransferase 1, Software verification and validation, Cluster analysis, ProMS_mo, Protein marker selection_multiomics, Molecular Biology, Selection (genetic algorithm), GO, gene ontology, 030304 developmental biology, PCA, principal component analysis, SVM, support vector machine, ProMS, Protein marker selection, Research, LPCAT1, lysophosphatidylcholine acyltransferase 1, TMT, tandem mass tag, PC, principal component, CRC, colorectal carcinoma, MS, mass spectrometry, HCC, hepatocellular carcinoma, Software, MRMR, maximum relevance minimum redundancy

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6146c14429ebd43f90ebe2bacfa30ae2Test
https://doi.org/10.1016/j.mcpro.2021.100083Test

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Reactive oxygen species and mitochondria: A nexus of cellular homeostasis

المؤلفون: Luis Alvarez, Xuezhi Zhang, Joe Dan Dunn, Thierry Soldati

المصدر: Redox Biology
Redox Biology, Vol. 6 (2015) pp. 472-485
REDOX BIOLOGY
Europe PubMed Central

مصطلحات موضوعية: ECSIT, evolutionarily conserved signaling intermediate in Toll pathways, Inflammasomes, Clinical Biochemistry, DAMP, damage-associated molecular pattern, LPS, lypopolysaccharide, Cellular homeostasis, MPO, myeloperoxidase, Review Article, Mitochondrion, ERRα, estrogen-related receptor α, Biochemistry, Neutrophil extracellular traps, Extracellular Traps, Inflammasome, TRAF6, tumor necrosis factor receptor-associated factor 6, Homeostasis, PI3K-I, class I phosphoinositide 3-kinase, NF-kB, nuclear factor-kB, STAT1, signal transducer and activator of transcription 1, ROS, reactive oxygen species, mainly superoxide and hydrogen peroxide, chemistry.chemical_classification, NLRP3, nucleotide binding domain-leucine rich repeat, pyrin domain-containing 3, TNF, tumor necrosis factor, TXNIP, thioredoxin-interacting protein, RIP1, receptor-interacting serine-threonine kinase 1, TOR, target of rapamycin, NOX, NADPH oxidase, PMA, phorbol myristate acetate, mtDAMP, mitochondrial damage-associated molecular pattern, 3. Good health, Cell biology, Mitochondria, Crosstalk (biology), TRX, thioredoxin, ddc:540, JNK, c-Jun N-terminal kinase, iNOS, inducible nitric oxide synthase, MAVS, mitochondrial antiviral signaling protein, Signal transduction, Oxidation-Reduction, Nrf2, NF-E2-related factor 2, PAMP, pathogen-associated molecular pattern, TLR, Toll-like receptor, TORC1, target of rapamycin complex 1, Signal Transduction, Cell signaling, NETs, neutrophil extracellular traps, VSV, vesicular stomatitis virus, eis, enhanced intracellular survival gene, ETC, electron transport chain, Mtb, Mycobacterium tuberculosis, TCA, tricarboxylic acid, PYD, pyrin domain, RIP3, receptor-interacting serine-threonine kinase 3, Biology, RAGE, receptor for advanced glycation end-products, SOD, superoxide dismutase, PKC, protein kinase C, Autophagy, Animals, Humans, IFN, interferon, Drp1, dynamin-related protein 1, Reactive oxygen species, NO, nitric oxide, DUSP16/MKP-7, dual specificity protein phosphatase 16/mitogen-activated protein kinase phosphatase-7, Organic Chemistry, Immunity, CGD, chronic granulomatous disease, NAC, N-acetyl-l-cysteine, ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain, G-CSF, granulocyte colony-stimulating factor, IL, interleukin, NLR, nucleotide binding domain-leucine rich repeat, PGC-1β, peroxisome proliferator-activated receptor γ coactivator-1β, chemistry, mtROS, ROS produced in the mitochondria, mTOR, target of rapamycin, mammalian homolog, Reactive Oxygen Species

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::736a9e18698874080ec5c5e030fb7fbcTest
http://europepmc.org/articles/PMC4596921Test

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Recent advances in the anti-HCV mechanisms of interferon

المؤلفون: Jian-Dong Jiang, Menghao Huang, Zong-Gen Peng

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 4, Iss 4, Pp 241-247 (2014)

مصطلحات موضوعية: USP18, ubiquitin specific peptidase 18, Antiviral agent, medicine.medical_treatment, SNPs, single-nucleotide polymorphisms, OAS, 2′-5′-oligoadenylate synthetase, Review, TYK2, tyrosine kinase 2, medicine.disease_cause, RLRs, RIG-I-like receptors, GWAS, genome-wide association studies, ISGs, IFN-stimulated genes, pDC, plasmacytoid dendritic cell, TLRs, Toll-like receptors, chemistry.chemical_compound, CHC, chronic hepatitis C, NKCs, natural killer cells, PRRs, pattern recognition receptors, Interferon, IFNAR2, interferon-alpha receptor 2, General Pharmacology, Toxicology and Pharmaceutics, SOC, standard of care, RIG-I, retinoic acid-inducible gene-I, STAT1, signal transducer and activator of transcription 1, E2, envelop 2, IL-29, interleukin-29, Hepatitis C virus, ISG15, interferon-stimulated gene 15, DNAM1, DNAX accessory molecule-1, virus diseases, TH1, T-helper-1, TH2, T-helper-2, Cytokine, IFNGR1, interferon gamma receptor 1, MAVS, mitochondrial antiviral signaling protein, IFNL4, IFN-lambda 4, DCs, dendritic cells, JAKs, Janus activated kinases, medicine.drug, IL-10R2, interleukin-10 receptor 2, ISGF3, IFN-stimulated gene factor 3, Standard of care, IFN-α, interferon-α, Biology, PKR, protein kinase R, Molecular mechanism, RdRp, RNA dependent RNA polymerase, Chronic hepatitis, PAMPs, pathogen-associated molecular patterns, medicine, ISREs, IFN-stimulated response elements, MHC, major histocompatibility complex, IFN, interferon, IRF-3, interferon regulatory factor 3, SVR, sustained virological response, STAT2, signal transducer and activator of transcription 2, NKTCs, natural killer T cells, PBMCs, peripheral blood mononuclear cells, Innate immune system, Anti hiv, Ribavirin, GAS, IFN-γ-activated site, lcsh:RM1-950, IRGs, IFN regulatory genes, IFNAR1, interferon-alpha receptor 1, IFNGR2, interferon gamma receptor 2, MDA-5, melanoma differentiation-associated gene-5, Virology, digestive system diseases, lcsh:Therapeutics. Pharmacology, chemistry, Immunology, dsRNA, double-stranded RNA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77a48b34b744dc874ff4d5273d5887fbTest

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Silica nanoparticles induce endoplasmic reticulum stress response, oxidative stress and activate the mitogen-activated protein kinase (MAPK) signaling pathway

المؤلفون: Verena Christen, Magdalena Camenzind, Karl Fent

المصدر: Toxicology Reports, Vol 1, Iss C, Pp 1143-1151 (2014)
Toxicology Reports

مصطلحات موضوعية: MAPK/ERK pathway, Health, Toxicology and Mutagenesis, eIF2α, eukaryotic initiation factor 2α, ATF-4, Activating transcription factor 4, Noxa, phorbol-12-myristate-13-acetate-induced protein 1, Toxicology, CREB, medicine.disease_cause, CHOP, CCAAT/enhancer binding protein-homologous protein, Article, MAPK, mitogen-activated protein kinase signaling pathway, p53, TP53-tumorsuppressor-gene, PERK, protein kinase like ER kinase, XBP-1, X-box binding protein 1, UPR, unfolded protein response, IFN α, interferon α, lcsh:RA1190-1270, NFκB, nuclear factor ‘kappa-light-chain-enhancer’ of activated B-cells, medicine, Protein kinase A, STAT1, signal transducer and activator of transcription 1, lcsh:Toxicology. Poisons, Proinflammatory response, Iinterferon-stimulated genes, biology, SiO2-NPs, silica nanoparticles, Tumor necrosis factor alpha, Endoplasmic reticulum, Human hepatoma cells, BiP, binding immunoglobulin protein, ISGs, interferon stiulated genes, Cell biology, TNFα, tumor necrosis factor α, IRE-1, inositol-requiring protein 1, IFN β, interferon β, ISG-15, interferon-induced 17 kDa protein, Mitogen-activated protein kinase, PP2A, protein phosphatase 2a, Immunology, ATF-6, activating transcription factor 6, biology.protein, Unfolded protein response, CREB, cAMP response element-binding protein, Signal transduction, Huh7, human hepatoma cells, IP-10, interferon gamma-induced protein 10, Oxidative stress, IRF-9, interferon regulatory factor 9

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57ecd7b912ae1263fdae8c13fa402bbTest

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رسالة جامعية

Nouveaux rôles anti-tumoraux de STAT1 : expression des immunoglobulines et réparation de l'ADN

New anti tumoralroles of STAT1 : immunoglobilin expression and DNA repair

المؤلفون: Lemadre, Elodie

مرشدي الرسالة: Paris 13, Varin-Blank, Nadine, Fabre, Emmanuelle

مصطلحات موضوعية: STAT1 (Transducteur de signaux et activateur de transcription 1), STAT1 (Signal Transducer and Activator of Transcription 1)

الإتاحة: http://www.theses.fr/2014PA132020/documentTest

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