Diagnosis, biology and epidemiology of oligometastatic breast cancer
| العنوان: | Diagnosis, biology and epidemiology of oligometastatic breast cancer |
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| المؤلفون: | Eleonora De Maio, Gabrielle Selmes, Slimane Zerdoud, Eva Jouve, R. Aziza, Jean-Louis Lacaze, Ciprian Chira, F. Izar, Florence Dalenc, C. Massabeau, Mony Ung, Anne Pradines |
| المصدر: | Breast, Vol 59, Iss, Pp 144-156 (2021) The Breast : Official Journal of the European Society of Mastology |
| بيانات النشر: | Elsevier, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Oncology, Review, NA, not applicable, Circulating Tumor DNA, law.invention, Circulating tumor cell, Randomized controlled trial, law, Epidemiology, HER2, human epidermal growth factor receptor 2, ctDNA, circulating tumor DNA, RC254-282, Curative intent, Incidence (epidemiology), Incidence, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, General Medicine, CTCs, circulating tumor cells, Neoplastic Cells, Circulating, Observational Studies as Topic, CT scan, Computed Tomography scan, 18F-FDG-PET/CT, Positron Emission Tomography/Computed Tomography with 18fluorodeoxyglucose, Female, CTCs, Cohort study, medicine.medical_specialty, 18F-FES, 16α-[18F]-Fluoro- 17β-estradiol, Breast Neoplasms, MRI, Magnetic Resonance Imaging, OMD, oligometastatic disease, OS, overall survival, MBC, Metastatic Breast Cancer, Breast cancer, Internal medicine, RFS, relapse-free survival, Biomarkers, Tumor, medicine, Humans, OMBC, oligometastatic breast cancer, Oligometastatic breast cancer, Biology, business.industry, HR, hormone receptor, Definition, medicine.disease, WB-MRI, Whole-body MRI, MicroRNAs, NED, No Evidence of Disease, SBR grade, Scarf-Bloom-Richardson grade, SBRT, Stereotactic Body Radiotherapy, Surgery, Observational study, Observatory, business |
| الوصف: | Does oligometastatic breast cancer (OMBC) deserve a dedicated treatment? Although some authors recommend multidisciplinary management of OMBC with a curative intent, there is no evidence proving this strategy beneficial in the absence of a randomized trial. The existing literature sheds little light on OMBC. Incidence is unknown; data available are either obsolete or biased; there is no consensus on the definition of OMBC and metastatic sites, nor on necessary imaging techniques. However, certain proposals merit consideration. Knowledge of eventual specific OMBC biological characteristics is limited to circulating tumor cell (CTC) counts. Given the data available for other cancers, studies on microRNAs (miRNAs), circulating tumor DNA (ctDNA) and genomic alterations should be developed Finally, safe and effective therapies do exist, but results of randomized trials will not be available for many years. Prospective observational cohort studies need to be implemented. Highlights • The incidence of oligometastatic breast cancer is unknown. • Only one publication provides information regarding the biology of these cancers. • Oligometastatic breast cancer and metastatic site definitions should be harmonized. • Prospective observational cohort studies are needed. |
| اللغة: | English |
| تدمد: | 1532-3080 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b69d7d75860baca5664d0f6f4d7d4a88Test http://www.sciencedirect.com/science/article/pii/S0960977621004069Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b69d7d75860baca5664d0f6f4d7d4a88 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15323080 |
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