يعرض 1 - 10 نتائج من 7,141 نتيجة بحث عن '"S5"', وقت الاستعلام: 1.04s تنقيح النتائج
  1. 1
    دورية أكاديمية
  2. 2
    دورية أكاديمية
  3. 3
    كتاب إلكتروني

    المؤلفون: Fritz, Peter, author

    المصدر: The Foundations of Modality : From Propositions to Possible Worlds, 2023.

  4. 4
    كتاب إلكتروني

    المؤلفون: Fritz, Peter, author

    المصدر: The Foundations of Modality : From Propositions to Possible Worlds, 2023.

  5. 5
    دورية أكاديمية
  6. 6
    كتاب إلكتروني

    المؤلفون: Russell, Gillian K., author

    المصدر: Barriers to Entailment : Hume's Law and other Limits on Logical Consequence, 2023, ill.

  7. 7
    دورية أكاديمية
  8. 8
  9. 9
    دورية أكاديمية
  10. 10
    دورية أكاديمية

    المصدر: RUHS Journal of Health Sciences (2023)

    مصطلحات موضوعية: Introduction: Many mutations have been reported in Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) since its first identification. Some are variants of concern (VOC) as they have higher transmission rates. Mutations in the spike protein region are of main concern as they affect transmission rates and can affect efficacy of the vaccines. The objective of present study was to look for spike protein mutations in SARS-CoV-2 using Next Generation Sequencing (NGS) in representative samples received in December 2020 at Rajasthan. Methodology: Ten nasopharyngeal/throat swab specimens from known COVID-19 positive patients were processed for RNA extraction, library preparation, and sequencing was done using specific SARS-CoV-2 Ion-Ampliseq panel by Ion torrent S5 system. Results: Only seven samples gave high quality data. All the isolates belonged to clade GH. We found 11 different mutations in the spike protein region most common were Q1201K, Q677R, D614G, L18F. Some novel mutations were found like S689I, Q23R, D1146E, andM153K. D614G mutation was present in all the samples which are known to promote transmissibility oftheSARS-CoV-2 virus. Conclusion: We did not find any VOC but one sample had N440K mutation which is reported to escape immune response, was found to be prevalent in some other parts of India also, and was considered epidemiologically important at the beginning of second wave. There is a need to carry out sequencing on regular basis to check for emerging mutants and monitor their effect on vaccine efficacy., Medicine

    وصف الملف: electronic resource