نتائج البحث - "Ryan A. Pak"

المساهمون: Institute for Medical Engineering and Science, Massachusetts Institute of Technology. Department of Biology, Dixit, Atray C., Regev, Aviv

المصدر: PMC
Cell, vol 167, iss 7

مصطلحات موضوعية: 0301 basic medicine, CRIPSRi, cell-to-cell heterogeneity, 1.1 Normal biological development and functioning, Computational biology, Biology, Protein Serine-Threonine Kinases, Medical and Health Sciences, General Biochemistry, Genetics and Molecular Biology, Article, Feedback, Vaccine Related, 03 medical and health sciences, Genetic, Models, Underpinning research, Endoribonucleases, Genetics, CRISPR, Animals, Humans, 2.1 Biological and endogenous factors, Clustered Regularly Interspaced Short Palindromic Repeats, Kinetoplastida, Aetiology, Gene, Psychological repression, Single-cell RNA-seq, CRISPR interference, genome-scale screening, single-cell genomics, Human Genome, Molecular, unfolded protein response, Biological Sciences, Translocon, Phenotype, 030104 developmental biology, Unfolded protein response, RNA, Single-Cell Analysis, Functional genomics, Sequence Analysis, Transcription, Guide, Biotechnology, Developmental Biology

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3e4c24839c7727cb125c7230b04e21Test
https://orcid.org/0000-0003-2193-9001Test

7

Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

المؤلفون: Jacqueline E. Villalta, Alexander P. Fields, Jacob E. Corn, Brittany Adamson, Yuwen Chen, Ryan A. Pak, Chong Yon Park, Max A. Horlbeck, Martin Kampmann, Jonathan S. Weissman, Luke A. Gilbert

المصدر: Kampmann, Martin; Gilbert, Luke; Horlbeck, MA; Gilbert, LA; Villalta, JE; Adamson, B; et al.(2016). Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/5b5017ckTest
eLife
eLife, Vol 5 (2016)

مصطلحات موضوعية: 0301 basic medicine, QH301-705.5, Science, animal diseases, Biology, Genome, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, Bacterial Proteins, CRISPR-Associated Protein 9, parasitic diseases, Animals, Humans, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Genomic library, Guide RNA, Biology (General), Gene, reproductive and urinary physiology, Subgenomic mRNA, Genetics, General Immunology and Microbiology, Genetic Screening, Cas9, General Neuroscience, fungi, Chromosome Mapping, General Medicine, Endonucleases, Nucleosomes, Chromatin, 030104 developmental biology, Genes and Chromosomes, Gene Targeting, Medicine, Insight, RNA, Guide, Kinetoplastida, Computational and Systems Biology, Human

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc1acae2dcfbfd4d96e77865fdb9971Test
https://doi.org/10.7554/elife.19760Test

8

Author response: Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation

المؤلفون: Chong Yon Park, Martin Kampmann, Yuwen Chen, Ryan A. Pak, Britt Adamson, Jacob E. Corn, Luke A. Gilbert, Max A. Horlbeck, Jacqueline E. Villalta, Alexander P. Fields, Jonathan S. Weissman

مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, 030104 developmental biology, CRISPR, Computational biology, Biology, Gene Repression

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::b394eff25760596a00ed54b1d641bf31Test
https://doi.org/10.7554/elife.19760.031Test

9

Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis

المؤلفون: Jonah R. Chan, Jinhua Wang, Kathy H. Li, Aaron D. Gitler, Amy A. Tang, John Q. Trojanowski, Alma L. Burlingame, Eileen H. Bigio, Anatoly Urisman, Eric J. Huang, Virginia M.-Y. Lee, William W. Seeley, Ana Jovičić, Teepu Siddique, Sebum Lee, Nathanael S. Gray, Stephanie A. Redmond, Yulei Shang, Ryan A. Pak

المصدر: Lee, S; Shang, Y; Redmond, SA; Urisman, A; Tang, AA; Li, KH; et al.(2016). Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis. NEURON, 91(1), 41-55. doi: 10.1016/j.neuron.2016.05.021. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/98t7g7j0Test
Neuron, vol 91, iss 1

مصطلحات موضوعية: 0301 basic medicine, SOD1, Mice, Transgenic, Neurodegenerative, Biology, Protein Serine-Threonine Kinases, Endoplasmic Reticulum, Transgenic, Article, 03 medical and health sciences, Mice, Rare Diseases, C9orf72, medicine, 2.1 Biological and endogenous factors, Psychology, Animals, Aetiology, Amyotrophic lateral sclerosis, Kinase activity, Protein kinase A, Motor Neurons, Neurology & Neurosurgery, Cell Death, Animal, Superoxide Dismutase, General Neuroscience, Endoplasmic reticulum, Neurodegeneration, Amyotrophic Lateral Sclerosis, Neurosciences, medicine.disease, Protein-Serine-Threonine Kinases, Brain Disorders, DNA-Binding Proteins, Disease Models, Animal, 030104 developmental biology, Spinal Cord, Neurological, Disease Models, Cancer research, Unfolded protein response, Cognitive Sciences, ALS, Carrier Proteins, Neuroglia, Biomarkers

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9eab20a55403798d2005e9292d74cea3Test
https://pubmed.ncbi.nlm.nih.gov/27321923Test

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