Factors associated with the presence of diabetic ketoacidosis: A retrospective analysis of patients with type 1 diabetes in Saudi Arabia

التفاصيل البيبلوغرافية
العنوان: Factors associated with the presence of diabetic ketoacidosis: A retrospective analysis of patients with type 1 diabetes in Saudi Arabia
المؤلفون: Asirvatham Alwin Robert, Ruqayah AL-Shaikh, Ayman A. Al Hayek, Mohamed Abdulaziz Al Dawish, Mohammed Alhojele, Alshehri Hanan Hassan, Daniyah Sabri, Mohammed Alenazi, Shaza Aloufi
المصدر: Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 14:2117-2122
بيانات النشر: Elsevier BV, 2020.
سنة النشر: 2020
مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, Adolescent, endocrine system diseases, Diabetic ketoacidosis, Endocrinology, Diabetes and Metabolism, Saudi Arabia, 030209 endocrinology & metabolism, Logistic regression, Diabetic Ketoacidosis, Young Adult, 03 medical and health sciences, Hba1c level, 0302 clinical medicine, Risk Factors, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Retrospective analysis, Humans, 030212 general & internal medicine, Retrospective Studies, Glycated Hemoglobin, Type 1 diabetes, business.industry, Incidence, nutritional and metabolic diseases, Retrospective cohort study, General Medicine, Prognosis, medicine.disease, Diabetes Mellitus, Type 1, Female, business, Body mass index, Biomarkers, Follow-Up Studies
الوصف: To Investigate the factors associated with Diabetic Ketoacidosis (DKA) among patients with type 1 diabetes (T1D).This was a descriptive, retrospective study conducted among 1118 patients with T1D, at the Prince Sultan Military Medical City, Riyadh, Saudi Arabia. After, exclusion process, 336 patients were selected for analysis. Among these, 105 patients with T1D were hospitalized for DKA, whereas 231 patients without DKA were outpatients who visited the hospital for T1D follow-up treatment.Bivariate analysis between patients with DKA and those without DKA revealed significant relationships in terms of gender (p = 0.014), age (p = 0.0001), body mass index (BMI) (p = 0.017), hemoglobin A1c (HbA1c) (p = 0.0001), duration of diabetes (p = 0.001) and clinic appointments (p = 0.001). From the logistic regression analysis, it was clear that females (OR 1.88; p = 0.038) had a higher risk for DKA. As compared to the age group of ≥30 years, those in the age category of 20-29 years (OR 1.35; p = 0.001) and teenagers (OR 3.64; p = 0.001) faced a higher risk of having DKA episodes. Compared with patients having HbA1c levels8%, those showing HbA1c levels 8-9.9% (OR 1.77; p = 0.224) and ≥10% (OR 4.06; p = 0.003) revealed higher risk for DKA. Likewise, in comparison with the patients who were compliant to clinic appointments, those who were non-compliant to clinic appointments exhibited higher than six times the risk (OR 6.38; p = 0.0001) of being more prone to experiencing the DKA episodes.Patients with higher risk for DKA comprise, those having high HbA1c levels, longer period of diabetes duration, teenagers, female gender and non-compliant to clinic appointments.
تدمد: 1871-4021
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8406f3e7cd01921874d949a45abbb678Test
https://doi.org/10.1016/j.dsx.2020.11.002Test
حقوق: CLOSED
رقم الانضمام: edsair.doi.dedup.....8406f3e7cd01921874d949a45abbb678
قاعدة البيانات: OpenAIRE