Evaluating the dual reactivity on SD bioline malaria rapid diagnosis tests as a potential indicator of high parasitemia due to Plasmodium falciparum
| العنوان: | Evaluating the dual reactivity on SD bioline malaria rapid diagnosis tests as a potential indicator of high parasitemia due to Plasmodium falciparum |
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| المؤلفون: | Vineeta Singh, Nathalie Amvongo-Adjia, Roger Moyou Somo, Valerie Makoge, Ngum Lesley Ngum, Roman Rodrigue Dongang Nana |
| المصدر: | Pathog Glob Health |
| بيانات النشر: | Informa UK Limited, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Plasmodium falciparum, Protozoan Proteins, Antigens, Protozoan, Parasitemia, Sensitivity and Specificity, Microbiology, Parasite load, Plasmodium, chemistry.chemical_compound, Antigen, Lactate dehydrogenase, parasitic diseases, Humans, Medicine, Parasite hosting, Malaria, Falciparum, biology, Diagnostic Tests, Routine, business.industry, Public Health, Environmental and Occupational Health, General Medicine, biology.organism_classification, medicine.disease, Virology, Malaria, Infectious Diseases, chemistry, Parasitology, business, Research Article |
| الوصف: | The co-reactivity of the Plasmodium histidine-rich protein 2 (HRP2) and lactate dehydrogenase (pLDH) in malaria rapid diagnosis tests (mRDTs) as a potential indicator of high parasitemia linked to Plasmodium falciparum was evaluated in the reported study from Cameroon. The samples were screened for malaria using both mRDTs (SD bioline HRP2/pLDH), light microscopy and further confirmed by Plasmodium species-specific PCR assay. Of the 483 patients enrolled, 161 (33.3%) showed a reactive mRDTs amongst which 70 patients were positive by both microscopy and mRDTs with 30.0% (21/70) positive for HRP2 alone, while 70.0% (49/70) showed a dual reaction to HRP2 and pLDH parasite antigens. P. falciparum parasitemia was found to be significantly high among patients with both reactive antigens, (p |
| تدمد: | 2047-7732 2047-7724 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f4eef4b487d946c355c59e04826d90cTest https://doi.org/10.1080/20477724.2021.1953684Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....1f4eef4b487d946c355c59e04826d90c |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 20477732 20477724 |
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