التفاصيل البيبلوغرافية
| العنوان: |
Concomitant oral tyrosine kinase inhibitors and bisphosphonates in advanced renal cell carcinoma with bone metastases. |
| المؤلفون: |
Beuselinck, B, Wolter, P, Karadimou, A, Elaidi, R, Dumez, Herlinde, Rogiers, Annick, Van Cann, T, Willems, L, Body, Jean-Jacques, Berkers, J, Van Poppel, H, Lerut, E, Debruyne, P, Paridaens, R, Schöffski, P |
| المصدر: |
British Journal of Cancer, 107 (10 |
| سنة النشر: |
2012 |
| المجموعة: |
DI-fusion : dépôt institutionnel de l'Université libre de Bruxelles (ULB) |
| مصطلحات موضوعية: |
Sciences bio-médicales et agricoles, Antineoplastic Combined Chemotherapy Protocols -- adverse effects -- therapeutic use, Bone Density Conservation Agents -- administration & dosage -- adverse effects, Bone Neoplasms -- drug therapy -- pathology -- secondary, Carcinoma, Renal Cell -- drug therapy -- pathology -- secondary, Diphosphonates -- administration & dosage -- adverse effects, Disease-Free Survival, Female, Humans, Indoles -- administration & dosage, Kidney Neoplasms -- drug therapy -- pathology, Male, Middle Aged, Neoplasm Metastasis, Niacinamide -- administration & dosage -- analogs & derivatives, Osteonecrosis -- chemically induced, Phenylurea Compounds -- administration & dosage, Prognosis, Protein Kinase Inhibitors -- administration & dosage, Protein-Tyrosine Kinases -- antagonists & inhibitors, Pyrroles -- administration & dosage, Retrospective Studies, Treatment Outcome, Bisphosphonates, Bone metastases, Osteonecrosis of the jaw, Outcome, Renal cell carcinoma, Targeted therapy |
| الوصف: |
The presence of bone metastases in patients with metastatic renal cell carcinoma treated with oral tyrosine kinase inhibitors (TKIs) is associated with poorer outcome as compared with patients without bone involvement. Concomitant bisphosphonates could probably improve outcomes but also induce osteonecrosis of the jaw (ONJ). ; Journal Article ; Research Support, Non-U.S. Gov't ; SCOPUS: ar.j ; info:eu-repo/semantics/published |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
1 full-text file(s): application/pdf |
| اللغة: |
English |
| العلاقة: |
uri/info:doi/10.1038/bjc.2012.385; uri/info:pii/bjc2012385; uri/info:pmid/23132391; uri/info:scp/84869225968; https://dipot.ulb.ac.be/dspace/bitstream/2013/143043/3/doi_126664.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/143043Test |
| الإتاحة: |
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/143043Test |
| رقم الانضمام: |
edsbas.4AA5440F |
| قاعدة البيانات: |
BASE |
