يعرض 1 - 10 نتائج من 324 نتيجة بحث عن '"Roberti, Marinella"', وقت الاستعلام: 1.73s تنقيح النتائج
  1. 1
    دورية أكاديمية
    New Horizons of Synthetic Lethality in Cancer: Current Development and Future Perspectives

    المؤلفون: Previtali, Viola, Bagnolini, Greta, Ciamarone, Andrea, Ferrandi, Giovanni, Rinaldi, Francesco, Myers, Samuel Harry, Roberti, Marinella, Cavalli, Andrea

    المصدر: Journal of Medicinal Chemistry ; ISSN 0022-2623 1520-4804

    الإتاحة: https://doi.org/10.1021/acs.jmedchem.4c00113Test

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  2. 2
    دورية أكاديمية
    An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer

    المؤلفون: Myers, Samuel H., Poppi, Laura, Rinaldi, Francesco, Veronesi, Marina, Ciamarone, Andrea, Previtali, Viola, Bagnolini, Greta, Schipani, Fabrizio, Ortega Martínez, Jose Antonio, Girotto, Stefania, Di Stefano, Giuseppina, Farabegoli, Fulvia, Walsh, Naomi, De Franco, Francesca, Roberti, Marinella, Cavalli, Andrea

    المساهمون: Airc Italian Foundation for Cancer Research, Istituto Italiano di Tecnologia, Associazione Italiana per la Ricerca sul Cancro, Università di Bologna

    المصدر: European Journal of Medicinal Chemistry ; volume 265, page 116114 ; ISSN 0223-5234

    مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Pharmacology, General Medicine

    الإتاحة: https://doi.org/10.1016/j.ejmech.2023.116114Test
    https://api.elsevier.com/content/article/PII:S0223523423010814?httpAccept=text/xmlTest
    https://api.elsevier.com/content/article/PII:S0223523423010814?httpAccept=text/plainTest

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  3. 3
    دورية أكاديمية
    Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5

    المؤلفون: Brusa, Irene, Sondo, Elvira, Pesce, Emanuela, Tomati, Valeria, Gioia, Dario, Falchi, Federico, Balboni, Beatrice, Ortega Martínez, Jose Antonio, Veronesi, Marina, Romeo, Elisa, Margaroli, Natasha, Recanatini, Maurizio, Girotto, Stefania, Pedemonte, Nicoletta, Roberti, Marinella, Cavalli, Andrea

    المساهمون: Brusa, Irene, Sondo, Elvira, Pesce, Emanuela, Tomati, Valeria, Gioia, Dario, Falchi, Federico, Balboni, Beatrice, Ortega Martínez, Jose Antonio, Veronesi, Marina, Romeo, Elisa, Margaroli, Natasha, Recanatini, Maurizio, Girotto, Stefania, Pedemonte, Nicoletta, Roberti, Marinella, Cavalli, Andrea

    مصطلحات موضوعية: CF, cystic fibrosis, CFTR, cystic fibrosis transmembrane conductance regulator, F508del, deletion of a phenylalanine 508, HMBC,Heteronuclear Multiple Bond Correlation, HS-YFP, halide-sensitive yellow fluorescent protein, MDC,monodansylcadaverine, MST, MicroScale Thermophoresis, NOE, Nuclear Overhauser Effect, PM, plasma membrane, RNF5, RING finger protein 5, STD, Saturation-Transfer Difference, WaterLOGSY, 1H Water-Ligand Observed via Gradient Spectros

    وصف الملف: ELETTRONICO

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/37440686; info:eu-repo/semantics/altIdentifier/wos/WOS:001027786000001; volume:66; issue:14; firstpage:9797; lastpage:9822; numberofpages:26; journal:JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11585/960259Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85165634323

    الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c00608Test
    https://hdl.handle.net/11585/960259Test

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  4. 4
    دورية أكاديمية
    The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination

    المؤلفون: Schipani, Fabrizio, Manerba, Marcella, Marotta, Roberto, Poppi, Laura, Gennari, Arianna, Rinaldi, Francesco, Armirotti, Andrea, Farabegoli, Fulvia, Roberti, Marinella, Di Stefano, Giuseppina, Rocchia, Walter, Girotto, Stefania, Tirelli, Nicola, Cavalli, Andrea

    المساهمون: Schipani, Fabrizio, Manerba, Marcella, Marotta, Roberto, Poppi, Laura, Gennari, Arianna, Rinaldi, Francesco, Armirotti, Andrea, Farabegoli, Fulvia, Roberti, Marinella, Di Stefano, Giuseppina, Rocchia, Walter, Girotto, Stefania, Tirelli, Nicola, Cavalli, Andrea

    مصطلحات موضوعية: BRCA2, DNA repair, PARP, anticancer drug discovery, chemo/radiosensitizer, homologous recombination, synthetic lethality, Peptide, BRCA2 Protein, Rad51 Recombinase

    وصف الملف: ELETTRONICO

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35955488; info:eu-repo/semantics/altIdentifier/wos/WOS:000838844000001; volume:23; issue:15; firstpage:1; lastpage:14; numberofpages:14; journal:INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES; https://hdl.handle.net/11585/900689Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85137087461; https://www.mdpi.com/1422-0067/23/15/8338/htmTest

    الإتاحة: https://doi.org/10.3390/ijms23158338Test
    https://hdl.handle.net/11585/900689Test
    https://www.mdpi.com/1422-0067/23/15/8338/htmTest

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  5. 5
    دورية أكاديمية
    Enriching Proteolysis Targeting Chimeras with a Second Modality: When Two Are Better Than One

    المؤلفون: Salerno, Alessandra, Seghetti, Francesca, Caciolla, Jessica, Uliassi, Elisa, Testi, Eleonora, Guardigni, Melissa, Roberti, Marinella, Milelli, Andrea, Bolognesi, Maria Laura

    المساهمون: Salerno, Alessandra, Seghetti, Francesca, Caciolla, Jessica, Uliassi, Elisa, Testi, Eleonora, Guardigni, Melissa, Roberti, Marinella, Milelli, Andrea, Bolognesi, Maria Laura

    مصطلحات موضوعية: Drug Discovery, Proteolysis targeting Chimera (PROTAC), Ubiquitin-Protein Ligase, multifunctional PROTACs

    وصف الملف: ELETTRONICO

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35816671; info:eu-repo/semantics/altIdentifier/wos/WOS:000828223100001; volume:65; issue:14; firstpage:9507; lastpage:9530; numberofpages:24; journal:JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11585/894851Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85135238812

    الإتاحة: https://doi.org/10.1021/acs.jmedchem.2c00302Test
    https://hdl.handle.net/11585/894851Test

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  6. 6
    دورية أكاديمية
    Identification of RAD51–BRCA2 Inhibitors Using N-Acylhydrazone-Based Dynamic Combinatorial Chemistry

    المؤلفون: Bagnolini, Greta, Balboni, Beatrice, Schipani, Fabrizio, Gioia, Dario, Veronesi, Marina, De Franco, Francesca, Kaya, Cansu, Jumde, Ravindra P., Ortega, Jose Antonio, Girotto, Stefania, Hirsch, Anna K. H., Roberti, Marinella, Cavalli, Andrea

    المساهمون: Istituto Italiano di Tecnologia, Associazione Italiana per la Ricerca sul Cancro, Universit? di Bologna, Helmholtz Association, H2020 European Research Council

    المصدر: ACS Medicinal Chemistry Letters ; volume 13, issue 8, page 1262-1269 ; ISSN 1948-5875 1948-5875

    الإتاحة: https://doi.org/10.1021/acsmedchemlett.2c00063Test

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  7. 7
    دورية أكاديمية
    Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives

    المؤلفون: Brusa, Irene, Sondo, Elvira, Falchi, Federico, Pedemonte, Nicoletta, Roberti, Marinella, Cavalli, Andrea

    المساهمون: Fondazione per la Ricerca sulla Fibrosi Cistica

    المصدر: Journal of Medicinal Chemistry ; volume 65, issue 7, page 5212-5243 ; ISSN 0022-2623 1520-4804

    الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c01897Test

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  8. 8
    دورية أكاديمية
    Inhibition of Urease, a Ni-Enzyme: The Reactivity of a Key Thiol With Mono- and Di-Substituted Catechols Elucidated by Kinetic, Structural, and Theoretical Studies

    المؤلفون: Mazzei, Luca, Contaldo, Umberto, Musiani, Francesco, Cianci, Michele, Bagnolini, Greta, Roberti, Marinella, Ciurli, Stefano

    المساهمون: Mazzei, Luca, Contaldo, Umberto, Musiani, Francesco, Cianci, Michele, Bagnolini, Greta, Roberti, Marinella, Ciurli, Stefano

    مصطلحات موضوعية: catechol, kinetics of enzyme inhibition, nickel, quantum mechanical calculation, urease crystal structure, enzyme inhibition

    وصف الملف: ELETTRONICO

    العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33245574; info:eu-repo/semantics/altIdentifier/wos/WOS:000613400100001; volume:60; issue:11; firstpage:6029; lastpage:6035; numberofpages:7; journal:ANGEWANDTE CHEMIE. INTERNATIONAL EDITION; http://hdl.handle.net/11566/287125Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85100305788

    الإتاحة: https://doi.org/10.1002/anie.202014706Test
    http://hdl.handle.net/11566/287125Test

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  9. 9
    دورية أكاديمية
    Identification of a 2,4-diaminopyrimidine scaffold targeting Trypanosoma brucei pteridine reductase 1 from the LIBRA compound library screening campaign

    المؤلفون: Linciano, Pasquale, Cullia, Gregorio, Borsari, Chiara, Santucci, Matteo, Ferrari, Stefania, Witt, Gesa, Gul, Sheraz, Kuzikov, Maria, Ellinger, Bernhard, Santarém, Nuno, Cordeiro da Silva, Anabela, Conti, Paola, Bolognesi, Maria Laura, Roberti, Marinella, Prati, Federica, Bartoccini, Francesca, Retini, Michele, Piersanti, Giovanni, Cavalli, Andrea, Goldoni, Luca, Bertozzi, Sine Mandrup, Bertozzi, Fabio, Brambilla, Enzo, Rizzo, Vincenzo, Piomelli, Daniele, Pinto, Andrea, Bandiera, Tiziano, Costi, Maria Paola

    المساهمون: Linciano, Pasquale, Cullia, Gregorio, Borsari, Chiara, Santucci, Matteo, Ferrari, Stefania, Witt, Gesa, Gul, Sheraz, Kuzikov, Maria, Ellinger, Bernhard, Santarém, Nuno, Cordeiro da Silva, Anabela, Conti, Paola, Bolognesi, Maria Laura, Roberti, Marinella, Prati, Federica, Bartoccini, Francesca, Retini, Michele, Piersanti, Giovanni, Cavalli, Andrea, Goldoni, Luca, Bertozzi, Sine Mandrup, Bertozzi, Fabio, Brambilla, Enzo, Rizzo, Vincenzo, Piomelli, Daniele, Pinto, Andrea, Bandiera, Tiziano, Costi, Maria Paola

    مصطلحات موضوعية: Anti-parasitic drug discovery, High throughput screening, LIBRA compound library, Pteridine reductase 1

    وصف الملف: STAMPA

    العلاقة: info:eu-repo/semantics/altIdentifier/wos/WOS:000518700000026; volume:189; firstpage:112047; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11576/2674208Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85078211471; https://www.sciencedirect.com/science/article/pii/S0223523420300143?via=ihubTest

    الإتاحة: https://doi.org/10.1016/j.ejmech.2020.112047Test
    https://hdl.handle.net/11576/2674208Test
    https://www.sciencedirect.com/science/article/pii/S0223523420300143?via=ihubTest

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  10. 10
    دورية أكاديمية
    Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib

    المؤلفون: Bagnolini, Greta, Milano, Domenico, Manerba, Marcella, Schipani, Fabrizio, Ortega, Jose Antonio, Gioia, Dario, Falchi, Federico, Balboni, Andrea, Farabegoli, Fulvia, De Franco, Francesca, Robertson, Janet, Pellicciari, Roberto, Pallavicini, Isabella, Peri, Sebastiano, Minucci, Saverio, Girotto, Stefania, Di Stefano, Giuseppina, Roberti, Marinella, Cavalli, Andrea

    المساهمون: Istituto Italiano di Tecnologia, Associazione Italiana per la Ricerca sul Cancro, Universit? di Bologna

    المصدر: Journal of Medicinal Chemistry ; volume 63, issue 5, page 2588-2619 ; ISSN 0022-2623 1520-4804

    الإتاحة: https://doi.org/10.1021/acs.jmedchem.9b01526Test

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