المؤلفون: Sneha Berry, Nicolas Giraldo, Peter Nguyen, Benjamin Green, Haiying Xu, Aleksandra Ogurtsova, Abha Soni, Farah Succaria, Daphne Wang, Charles Roberts, Julie Stein, Elizabeth Engle, Drew Pardoll, Robert Anders, Tricia Cottrell, Janis M. Taube, Ben Tran, Mark Voskoboynik, James Kuo, Yung-Lue Bang, Hyun-Cheo Chung, Myung-Ju Ahn, Sang-We Kim, Ayesh Perera, Daniel Freeman, Ikbel Achour, Raffaella Faggioni, Feng Xiao, Charles Ferte, Charlotte Lemech, Funda Meric-Bernstam, Theresa Werner, Stephen Hodi, Wells Messersmith, Nancy Lewis, Craig Talluto, Mirek Dostalek, Aiyang Tao, Sarah McWhirter, Damian Trujillo, Jason Luke, Chunxiao Xu, BoMarelli, Jin Qi, Guozhong Qin, Huakui Yu, Molly Jenkins, Kin-Ming Lo, Joern-Peter Halle, Yan Lan, Matthew Taylor, Nicholas Vogelzang, Allen Cohn, Daniel Stepan, Robert Shumaker, Corina Dutcus, Matthew Guo, Emmett Schmidt, Drew Rasco, Marcia Brose, Christopher Di Simone, Sharad Jain, Donald Richards, Carlos Encarnacion, James Mier, Jeongshin An, Yeun-yeoul Yang, Won-Hee Lee, Jinho Yang, Jong-kyu Kim, Hyun Goo Kim, Se Hyun Paek, Jun Woo Lee, Joohyun Woo, Jong Bin Kim, Hyungju Kwon, Woosung Lim, Nam Sun Paik, Yoon-Keun Kim, Byung-In Moon, Filip Janku, David Tan, Juan Martin-Liberal, Shunji Takahashi, Ravit Geva, Ayca Gucalp, Xueying Chen, Kulandayan Subramanian, Jennifer Mataraza, Jennifer Wheler, Philippe Bedard

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)

مصطلحات موضوعية: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

العلاقة: http://link.springer.com/article/10.1186/s40425-019-0519-yTest; https://doaj.org/toc/2051-1426Test

الوصول الحر: https://doaj.org/article/5e0fdcdf298e4148a8ad792b96d6446aTest

المؤلفون: John Nemunaitis, James P. O'Brien, Pallavi Sachdev, Corina Andresen, Cynthia Bedell, Jennifer Mink, Min Ren, Robert Shumaker, Lucy Xu, Goldy C. George, Ly M. Nguyen, Michael A. Davies, Kevin B. Kim, Siqing Fu, Gerald S. Falchook, Aung Naing, Jennifer J. Wheler, Razelle Kurzrock, David S. Hong

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f763894bc770dba6ac95ef69cfb9c40Test
https://doi.org/10.1158/1078-0432.22458195Test

المؤلفون: John Nemunaitis, James P. O'Brien, Pallavi Sachdev, Corina Andresen, Cynthia Bedell, Jennifer Mink, Min Ren, Robert Shumaker, Lucy Xu, Goldy C. George, Ly M. Nguyen, Michael A. Davies, Kevin B. Kim, Siqing Fu, Gerald S. Falchook, Aung Naing, Jennifer J. Wheler, Razelle Kurzrock, David S. Hong

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3839d647413c4a841ebad871c41ed31eTest
https://doi.org/10.1158/1078-0432.c.6523866.v1Test

المؤلفون: Pallavi Sachdev, Vicky Makker, Marcia S. Brose, Ana Oaknin, Mark Messing, Antonio Casado Herraez, Emmett V. Schmidt, Daniel E. Stepan, Christopher DiSimone, Margarita Romeo, Raquel Bratos, Carol Aghajanian, Allen Lee Cohn, James W. Mier, Robert Orlowski, Corina E. Dutcus, Jane Wu, Matthew H. Taylor, Robert Shumaker

المساهمون: Institut Català de la Salut, [Makker V, Aghajanian C] Memorial Sloan Kettering Cancer Center, New York, NY, USA. [Taylor MH] Oregon Health & Science University, Portland, OR, USA. [Oaknin A] Vall d’Hebron Hospital Universitari, Barcelona, Spain. Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain. [Mier J] Beth Israel Deaconess Medical Center, Boston, MA, USA. [Cohn AL] Rocky Mountain Cancer Center, Denver, CO, USA, Vall d'Hebron Barcelona Hospital Campus

المصدر: Journal of Clinical Oncology
Scientia

مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Time Factors, Pembrolizumab, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Carcinoma, Humans, In patient, Other subheadings::/therapeutic use [Other subheadings], Progression-free survival, terapéutica::protocolos clínicos::protocolos antineoplásicos::protocolos de quimioterapia antineoplásica combinada [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS], Aged, Medicaments antineoplàstics - Ús terapèutic - Eficàcia, Otros calificadores::/uso terapéutico [Otros calificadores], business.industry, Endometrial cancer, Phenylurea Compounds, Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Genital Neoplasms, Female::Uterine Neoplasms::Endometrial Neoplasms [DISEASES], ORIGINAL REPORTS, Therapeutics::Clinical Protocols::Antineoplastic Protocols::Antineoplastic Combined Chemotherapy Protocols [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT], Middle Aged, medicine.disease, Progression-Free Survival, Endometrial Neoplasms, Clinical trial, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Cohort, Disease Progression, Quinolines, Endometri - Càncer, Female, Microsatellite Instability, neoplasias::neoplasias por localización::neoplasias urogenitales::neoplasias de los genitales femeninos::neoplasias uterinas::neoplasias endometriales [ENFERMEDADES], Lenvatinib, business, Gynecological Cancer

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793cb8c5e2eacb838cdb56ab05a426c5Test
https://pubmed.ncbi.nlm.nih.gov/32167863Test

المؤلفون: Christian Rance, Min Ren, Jagadeesh Aluri, Cixin He, Corina E. Dutcus, Robert Shumaker

المصدر: European Journal of Drug Metabolism and Pharmacokinetics

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Midazolam, Antineoplastic Agents, 030226 pharmacology & pharmacy, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, Internal medicine, Neoplasms, medicine, Cytochrome P-450 CYP3A, Humans, Pharmacology (medical), In patient, Drug Interactions, Original Research Article, Adverse effect, Aged, Pharmacology, Aged, 80 and over, CYP3A4, business.industry, Phenylurea Compounds, Middle Aged, Confidence interval, chemistry, 030220 oncology & carcinogenesis, Area Under Curve, Quinolines, Female, business, Lenvatinib, Drug metabolism, medicine.drug, Half-Life

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26706c2081684889e18f7000a5e4ed83Test
https://pubmed.ncbi.nlm.nih.gov/32067158Test

المؤلفون: Chung-Han Lee, Robert Shumaker, Drew W. Rasco, Robert J. Motzer, Matthew H. Taylor, Daniel E. Stepan, Jane Wu, Vicky Makker, Corina E. Dutcus

المصدر: J Clin Oncol
Journal of Clinical Oncology

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, Maximum Tolerated Dose, Pembrolizumab, Antibodies, Monoclonal, Humanized, Cohort Studies, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Immune system, Renal cell carcinoma, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Carcinoma, medicine, Humans, Clinical Trials, Carcinoma, Renal Cell, Melanoma, Aged, Aged, 80 and over, biology, Errata, business.industry, Endometrial cancer, Phenylurea Compounds, ORIGINAL REPORTS, Middle Aged, medicine.disease, Kidney Neoplasms, Endometrial Neoplasms, 030104 developmental biology, Oncology, chemistry, 030220 oncology & carcinogenesis, Monoclonal, biology.protein, Cancer research, Quinolines, Female, Antibody, Lenvatinib, business

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50dd3df0cb9478f7652fc27f4d985f12Test
https://pubmed.ncbi.nlm.nih.gov/32755510Test

المؤلفون: Robert Shumaker

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::668f9e55923ac7e8484f233911285502Test
https://doi.org/10.1353/book.78114Test

المؤلفون: Pallavi Sachdev, R Bratos Lorenzo, Daniel E. Stepan, A. Casado Herraez, Jane Wu, Robert Shumaker, M. Romeo Marin, Emmett V. Schmidt, Allen Lee Cohn, Marcia S. Brose, Matthew H. Taylor, James W. Mier, Robert Orlowski, Vicky Makker, Ana Oaknin, Mark Messing, Christopher DiSimone, Carol Aghajanian, Corina E. Dutcus

المصدر: Annals of Oncology. 30:v404-v405

مصطلحات موضوعية: 0301 basic medicine, Antitumor activity, medicine.medical_specialty, business.industry, Hematology, Pembrolizumab, Multikinase inhibitor, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, Oncology, chemistry, Modified recist, 030220 oncology & carcinogenesis, Family medicine, Partial response, medicine, business, Lenvatinib, Objective response, Complete response

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::7965d4727bb457441caa7e446f22c016Test
https://doi.org/10.1093/annonc/mdz250.002Test

المؤلفون: Barbara Jarzab, Ziad Hussein, Anubha Gupta, Robert Shumaker, Jaume Capdevila

المصدر: British Journal of Clinical Pharmacology. 81:1124-1133

مصطلحات موضوعية: Pharmacology, education.field_of_study, CYP3A4, business.industry, Population, Renal function, Phases of clinical research, 030226 pharmacology & pharmacy, Bioavailability, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Pharmacokinetics, chemistry, 030220 oncology & carcinogenesis, Concomitant, Medicine, Pharmacology (medical), business, education, Lenvatinib

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::fe88a2af12073a29d85df74011cfb327Test
https://doi.org/10.1111/bcp.12907Test

المؤلفون: Hitoshi Mizuo, Jos H. Beijnen, Robert S. Jansen, A. C. Dubbelman, David Critchley, Shinki Kawaguchi, Hilde Rosing, Jan H.M. Schellens, C.M. Nijenhuis, Robert Shumaker

المصدر: Investigational New Drugs, 34(3), 300. Kluwer Academic Publishers

مصطلحات موضوعية: Male, medicine.drug_class, Glucuronidation, Administration, Oral, Antineoplastic Agents, Urine, Mass balance, Pharmacology, 030226 pharmacology & pharmacy, Mass Spectrometry, Tyrosine-kinase inhibitor, Rats, Sprague-Dawley, Hydroxylation, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Species Specificity, Pharmacokinetics, medicine, Lenvatinib, Animals, Humans, Pharmacology (medical), Protein Kinase Inhibitors, Phenylurea Compounds, Metabolite identification, Metabolism, Rats, Macaca fascicularis, Oncology, chemistry, Biochemistry, 030220 oncology & carcinogenesis, Quinolines, Clinical pharmacology, Drug metabolism, Chromatography, Liquid

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd39856658a15cba71a6c483e7e6307Test
https://doi.org/10.1007/s10637-016-0342-yTest