نتائج البحث - "Rob Tierney"

المساهمون: Technische Universität Braunschweig = Technical University of Braunschweig [Braunschweig], Bactéries anaérobies et Toxines, Institut Pasteur [Paris] (IP), National Institute for Biological Standards and Control (NIBSC), Medicines and Healthcare Products Regulatory Agency (MHRA), Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), LFB Biotechnologies, We acknowledge funding from the European Community’s Seventh Framework Program (FP7/2007-2013) under agreement no. 241832 granted to the AntiBotABE project. LFB Biotechnologies provided support in the form of salaries for authors RU and A. Fontayne, but did not have any additional role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript. The specific roles of these authors are articulated in the ‘author contributions’ section., We thank Olivier De Bardonneche (Absiskey) for his excellent project management work in the AntibotABE project., European Project: 241832,EC:FP7:SEC,FP7-SEC-2009-1,ANTIBOTABE(2010), Institut Pasteur [Paris], Institut de Recherche Biomédicale des Armées (IRBA)

المصدر: PLoS ONE, Vol 11, Iss 8, p e0161446 (2016)
PLoS ONE
PLoS ONE, 2016, 11 (8), pp.e0161446. ⟨10.1371/journal.pone.0161446⟩
PLoS ONE, Public Library of Science, 2016, 11 (8), pp.e0161446. ⟨10.1371/journal.pone.0161446⟩

مصطلحات موضوعية: 0301 basic medicine, Serotype, Bacterial Diseases, Physiology, [SDV]Life Sciences [q-bio], lcsh:Medicine, Monkeys, medicine.disease_cause, Toxicology, Pathology and Laboratory Medicine, Biochemistry, Neutralization, MESH: Antibodies, Neutralizing, Mice, 0302 clinical medicine, Immune Physiology, Clostridium botulinum, Medicine and Health Sciences, Toxins, Botulism, MESH: Animals, 030212 general & internal medicine, Botulinum Toxins, Type A, Enzyme-Linked Immunoassays, lcsh:Science, MESH: Immunoglobulin G, Mammals, MESH: Single-Chain Antibodies, Multidisciplinary, Immune System Proteins, biology, MESH: Neutralization Tests, Antigenic Variation, 3. Good health, Infectious Diseases, [SDV.TOX]Life Sciences [q-bio]/Toxicology, Monoclonal, Vertebrates, Female, Antibody, Macaque, Research Article, Primates, MESH: Clostridium botulinum, Toxic Agents, Immunology, Bacterial Toxins, Botulinum Toxin, MESH: Botulism, Immunoglobulin light chain, Antibodies, Monoclonal, Humanized, Research and Analysis Methods, Antibodies, Microbiology, 03 medical and health sciences, Neutralization Tests, Old World monkeys, medicine, Antigenic variation, Animals, Humans, Antigens, Immunoassays, MESH: Mice, MESH: Humans, Biology and life sciences, Toxicity, MESH: Botulinum Toxins, Type A, lcsh:R, Organisms, Proteins, medicine.disease, Virology, Antibodies, Neutralizing, Macaca fascicularis, 030104 developmental biology, MESH: Macaca fascicularis, MESH: Antibodies, Monoclonal, Humanized, Immunoglobulin G, Amniotes, biology.protein, Immunologic Techniques, lcsh:Q, MESH: Female, Single-Chain Antibodies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c596170dd8ed0dfef3dce1c3880b5530Test
http://europepmc.org/articles/PMC4999263?pdf=renderTest

7

Development of human-like scFv-Fc antibodies neutralizing Botulinum toxin serotype B

المؤلفون: Philippe Thullier, Siham Chahboun, Thibaut Pelat, Rob Tierney, Dorothea Sesardic, Christine Rasetti-Escargueil, Michel R. Popoff, Nicola Bak, Sebastian Miethe, Arnaud Avril, Michael Hust, Christelle Mazuet

المساهمون: National Institute for Biological Standards and Control (NIBSC), Medicines and Healthcare Products Regulatory Agency (MHRA), Institut de Recherche Biomédicale des Armées (IRBA), Technische Universität Braunschweig = Technical University of Braunschweig [Braunschweig], Bactéries anaérobies et Toxines, Institut Pasteur [Paris], We acknowledge funding from the European Community Seventh Framework Program (FP7/2007–2013) under agreement N° 241832 granted to the AntiBotABE project (http://www.antibotabe.comTest)., European Project: 241832,EC:FP7:SEC,FP7-SEC-2009-1,ANTIBOTABE(2010), Institut de Recherche Biomédicale des Armées [Brétigny-sur-Orge] (IRBA), Institut Pasteur [Paris] (IP), National Institute for Biological Standards and Control ( NIBSC ), Institut de Recherche Biomédicale des Armées ( IRBA ), Technische Universität Braunschweig [Braunschweig], European Project : 241832,EC:FP7:SEC,FP7-SEC-2009-1,ANTIBOTABE ( 2010 )

المصدر: mAbs
mAbs, Taylor & Francis, 2015, 7 (6), pp.1161-1177. ⟨10.1080/19420862.2015.1082016⟩
mAbs, 2015, 7 (6), pp.1161-1177. ⟨10.1080/19420862.2015.1082016⟩
mAbs, Taylor & Francis, 2015, 7 (6), pp.1161-1177. 〈10.1080/19420862.2015.1082016〉

مصطلحات موضوعية: Phage display, [ SDV.TOX ] Life Sciences [q-bio]/Toxicology, Immunology, Antibody Affinity, Cross Reactions, botulinum neurotoxins, BoNT/B, VAMP2, in vitro endopeptidase, ex vivo mouse phrenic nerve-hemidiaphragm, neutralization assays, scFv-Fc, mouse paralysis, synergistic protection macaque, medicine.disease_cause, Neutralization, Mice, Endopeptidase activity, Antibody Specificity, Peptide Library, In vivo, synergistic protection macaque, Report, medicine, BoNT/B, Animals, Humans, Paralysis, Immunology and Allergy, botulinum neurotoxins, Botulism, Botulinum Toxins, Type A, in vitro endopeptidase, neutralization assays, scFv-Fc, Clostridium, biology, Toxin, Monkey Diseases, ex vivo mouse phrenic nerve-hemidiaphragm, medicine.disease, Antibodies, Neutralizing, Virology, 3. Good health, Phrenic Nerve, Macaca fascicularis, VAMP2, mouse paralysis, [SDV.TOX]Life Sciences [q-bio]/Toxicology, biology.protein, Immunization, Antibody, Ex vivo, Single-Chain Antibodies