المؤلفون: Rostami, Jinar, Jäntti, Maria, Cui, Hengjing, Rinne, Maiju K., Kukkonen, Jyrki P., Falk, Anna, Erlandsson, Anna, Myöhänen, Timo

المصدر: Biomedicine and Pharmacotherapy. 131

مصطلحات موضوعية: Alpha-synuclein, Autophagy, Calpain, Fibrils, Neurodegeneration, Propagation, Synucleinopathies

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-425463Test
https://doi.org/10.1016/j.biopha.2020.110788Test
https://uu.diva-portal.org/smash/get/diva2:1501140/FULLTEXT01.pdfTest

المؤلفون: Rostami, Jinar, Jäntti, Maria, Cui, Hengjing, Rinne, Maiju K., Kukkonen, Jyrki P., Falk, Anna, Erlandsson, Anna, Myöhänen, Timo

المصدر: Biomedicine & Pharmacotherapy ; volume 133, page 111019 ; ISSN 0753-3322

مصطلحات موضوعية: Pharmacology, General Medicine

الإتاحة: https://doi.org/10.1016/j.biopha.2020.111019Test
https://api.elsevier.com/content/article/PII:S0753332220312117?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0753332220312117?httpAccept=text/plainTest

المؤلفون: Rinne, Maiju K., Leino, Teppo O., Turku, Ainoleena, Turunen, Pauli M., Steynen, Yana, Xhaard, Henri, Wallen, Erik A. A., Kukkonen, Jyrki P.

المساهمون: Faculty of Pharmacy, Division of Pharmaceutical Chemistry and Technology, Veterinary Biosciences, Departments of Faculty of Veterinary Medicine, Pharmaceutical Design and Discovery group, Medicum, Department of Physiology, Veterinary Biochemistry and Cell Biology, Henri Xhaard / Principal Investigator, Computational Adme, Drug Research Program, Erik Wallen / Principal Investigator, Jyrki Kukkonen / Principal Investigator, Medicinal Chemistry research group

مصطلحات موضوعية: Orexin, Calcium, Phospholipase C, cAMP, Cell death, ERK, ACTIVATED PROTEIN-KINASE, OREXIN TYPE-2 RECEPTOR, HAMSTER OVARY CELLS, OX1 RECEPTOR, NARCOLEPSY, SLEEP, MICE, WAKEFULNESS, APOPTOSIS, GENE, 317 Pharmacy

وصف الملف: application/pdf

العلاقة: Santeri Suokas, Marja Peltola and Jouni Oksanen (Biochemistry and Cell Biology, Department of Veterinary Biosciences, University of Helsinki) are gratefully acknowledged for technical assistance with the experiments, and Kaj-Roger Hurme (Instrument Centre of Faculty of Agriculture and Forestry, University of Helsinki) and Raija Savolainen (Institute of Biotechnology, University of Helsinki) for all help with the liquid scintillation counting and luminescence measurements, respectively. This work was supported by the European Union (FP7-HEALTHproject GLORIA [# 602919]), the Magnus Ehrnrooth Foundation, the Finnish Cultural Foundation, the Orion Research Foundation, the Liv & Halsa Foundation, and the Doctoral Program in Drug Research of the University of Helsinki.; Rinne , M K , Leino , T O , Turku , A , Turunen , P M , Steynen , Y , Xhaard , H , Wallen , E A A & Kukkonen , J P 2018 , ' Pharmacological characterization of the orexin/hypocretin receptor agonist Nag 26 ' , European Journal of Pharmacology , vol. 837 , pp. 137-144 . https://doi.org/10.1016/j.ejphar.2018.09.003Test; ORCID: /0000-0003-0959-7221/work/49162309; ORCID: /0000-0003-2582-7971/work/49162603; ORCID: /0000-0002-3129-1678/work/49160715; ORCID: /0000-0002-6989-1564/work/63349243; ORCID: /0000-0003-3218-2841/work/68616121; http://hdl.handle.net/10138/305214Test; aff2e1b3-c4b3-4caf-a9e3-98c8277aa516; 85053081769; 000444963400016

الإتاحة: http://hdl.handle.net/10138/305214Test

المؤلفون: Turku, Ainoleena, Rinne, Maiju K., af Gennas, Gustav Boije, Xhaard, Henri, Lindholm, Dan, Kukkonen, Jyrki P.

المساهمون: Faculty of Pharmacy, Division of Pharmaceutical Chemistry and Technology, University of Helsinki, Veterinary Biosciences, Veterinary Biochemistry and Cell Biology, Pharmaceutical Design and Discovery group, Drug Research Program, Henri Xhaard / Principal Investigator, Medicum, Department of Biochemistry and Developmental Biology, Departments of Faculty of Veterinary Medicine, Jyrki Kukkonen / Principal Investigator

مصطلحات موضوعية: HAMSTER OVARY CELLS, OX1 RECEPTOR, APOPTOSIS, ANTAGONISTS, NARCOLEPSY, WAKEFULNESS, NECROSIS, CANCER, DEATH, MODEL, 317 Pharmacy, 3111 Biomedicine

وصف الملف: application/pdf

العلاقة: Support was provided by the Academy of Finland, Gustav Boije af Gennas, grant number 257685 [http://www.aka.fi/enTest/]; Finnish Cultural Foundation, Ainoleena Turku [https://skr.fi/enTest]; University of Helsinki Research Funds, Henri Xhaard [https://www.helsinki.fi/en/studying/during-your-studies/apply-for-a-grantTest]; Magnus Ehrnrooth Foundation, Dan Lindholm, Jyrki Kukkonen [http://www.magliusehrnroothinsaatio.fi/enTest/]; Waldemar von Frenckell Foundation, Gustav Boije of Gennas [http://www.fourdationweb.net/frenckellTest/]; Liv & Halsa Foundation, Dan Lindholm, Jyrki Kukkonen [http://www.livochhalda.fiTest/].; Turku , A , Rinne , M K , af Gennas , G B , Xhaard , H , Lindholm , D & Kukkonen , J P 2017 , ' Orexin receptor agonist Yan 7874 is a weak agonist of orexin/hypocretin receptors and shows orexin receptor-independent cytotoxicity ' , PLoS One , vol. 12 , no. 5 , 0178526 . https://doi.org/10.1371/journal.pone.0178526Test; ORCID: /0000-0002-0099-6085/work/34564398; ORCID: /0000-0003-0959-7221/work/40982588; ORCID: /0000-0002-6989-1564/work/63349303; ORCID: /0000-0003-3218-2841/work/68616122; 85020298695; b4d40b20-4187-44cd-a828-7f96e9c4e87a; http://hdl.handle.net/10138/195933Test; 000402624300061

الإتاحة: http://hdl.handle.net/10138/195933Test

المؤلفون: Rinne, Maiju K., Leino, Teppo O., Turku, Ainoleena, Turunen, Pauli M., Steynen, Yana, Xhaard, Henri, Wallén, Erik A.A., Kukkonen, Jyrki P.

المساهمون: European Union, Magnus Ehrnrooth Foundation, Finnish Cultural Foundation, Orion Research Foundation, Liv & Hälsa Foundation, Doctoral Program in Drug Research of the University of Helsinki

المصدر: European Journal of Pharmacology ; volume 837, page 137-144 ; ISSN 0014-2999

مصطلحات موضوعية: Pharmacology

الإتاحة: https://doi.org/10.1016/j.ejphar.2018.09.003Test
https://api.elsevier.com/content/article/PII:S0014299918305193?httpAccept=text/xmlTest
https://api.elsevier.com/content/article/PII:S0014299918305193?httpAccept=text/plainTest

المؤلفون: Rinne, Maiju K

المساهمون: Biologian laitos, Department of Biology, Luonnontieteiden ja metsätieteiden tiedekunta, Biologian laitos, Faculty of Science and Forestry, Department of Biology, Luonnontieteiden ja metsätieteiden tiedekunta, Faculty of Science and Forestry

مصطلحات موضوعية: biologia, biology

وصف الملف: fulltext; Julkaisun kokoteksti; Fulltext of publication

العلاقة: https://erepo.uef.fi/handle/123456789/10968Test; http://urn.fi/urn:nbn:fi:uef-20120716Test

الإتاحة: https://erepo.uef.fi/handle/123456789/10968Test
http://urn.fi/urn:nbn:fi:uef-20120716Test