دورية أكاديمية
Repurposing Know-how for Drug Development: Case Studies from the Swiss Tropical and Public Health Institute
| العنوان: | Repurposing Know-how for Drug Development: Case Studies from the Swiss Tropical and Public Health Institute |
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| المؤلفون: | Meier, Lukas, Antillon, Marina, Burri, Christian, Chitnis, Nakul, Endriss, Yvette, Keiser, Jennifer, Moore, Sarah, Müller, Pie, Penny, Melissa A., Voss, Till S., Mäser, Pascal, Utzinger, Jürg |
| المصدر: | CHIMIA; Bd. 77 Nr. 9 (2023): Swiss TPH: 30 Years of R&D Towards New Drugs for Tropical Diseases ; 582-592 ; CHIMIA; Vol. 77 No. 9 (2023): Swiss TPH: 30 Years of R&D Towards New Drugs for Tropical Diseases ; 2673-2424 ; 0009-4293 |
| بيانات النشر: | Swiss Chemical Society |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Drug development, Drug discovery, Human African trypanosomiasis, Malaria, Neglected tropical diseases, Product development partnerships, Public-private partnerships, Repurposing know-how, Schistosomiasis, Swiss Tropical and Public Health Institute |
| الوصف: | In pursuing novel therapeutic solutions, drug discovery and development rely on efficiently utilising existing knowledge and resources. Repurposing know-how, a strategy that capitalises on previously acquired information and expertise, has emerged as a powerful approach to accelerate drug discovery and development processes, often at a fraction of the costs of de novo developments. For 80 years, collaborating within a network of partnerships, the Swiss Tropical and Public Health Institute (Swiss TPH) has been working along a value chain from innovation to validation and application to combat poverty-related diseases. This article presents an overview of selected know-how repurposing initiatives conducted at Swiss TPH with a particular emphasis on the exploration of drug development pathways in the context of neglected tropical diseases and other infectious diseases of poverty, such as schistosomiasis, malaria and human African trypanosomiasis. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| العلاقة: | https://www.chimia.ch/chimia/article/view/2023_582/6292Test; https://www.chimia.ch/chimia/article/view/2023_582Test |
| DOI: | 10.2533/chimia.2023.582 |
| الإتاحة: | https://doi.org/10.2533/chimia.2023.582Test https://www.chimia.ch/chimia/article/view/2023_582Test |
| حقوق: | Copyright (c) 2023 Lukas Meier, Marina Antillon, Christian Burri, Nakul Chitnis, Yvette Endriss, Jennifer Keiser, Sarah Moore, Pie Müller, Melissa Penny, Till S. Voss, Pascal Mäser, Jürg Utzinger ; https://creativecommons.org/licenses/by/4.0Test |
| رقم الانضمام: | edsbas.7D8853FF |
| قاعدة البيانات: | BASE |
| DOI: | 10.2533/chimia.2023.582 |
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