المؤلفون: Jyoti Naik, Maria Themeli, Regina de Jong-Korlaar, Ruud W.J. Ruiter, Pino J Poddighe, Huipin Yuan, Joost D. de Bruijn, Gert J. Ossenkoppele, Sonja Zweegman, Linda Smit, Tuna Mutis, Anton C.M. Martens, Niels W.C.J. van de Donk, Richard W.J. Groen

المصدر: Haematologica, Vol 104, Iss 3 (2019)

مصطلحات موضوعية: Diseases of the blood and blood-forming organs, RC633-647.5

وصف الملف: electronic resource

العلاقة: https://haematologica.org/article/view/8821Test; https://doaj.org/toc/0390-6078Test; https://doaj.org/toc/1592-8721Test

الوصول الحر: https://doaj.org/article/89ff26f4897c498783e18e45ab598f0cTest

المؤلفون: Regina de Jong-Korlaar, Renée Poels, Huipin Yuan, Anton C.M. Martens, Henk M. Lokhorst, Joost D. de Bruijn, Richard W.J. Groen, Niels W.C.J. van de Donk, Esther Drent, Tuna Mutis, Maria Themeli, Sonja Zweegman

المساهمون: Hematology laboratory, CCA - Cancer biology and immunology, Hematology

المصدر: Drent, E, Themeli, M, Poels, R, de Jong-Korlaar, R, Yuan, H, de Bruijn, J, Martens, A C M, Zweegman, S, van de Donk, N W C J, Groen, R W J, Lokhorst, H M & Mutis, T 2017, ' A Rational Strategy for Reducing On-Target Off-Tumor Effects of CD38-Chimeric Antigen Receptors by Affinity Optimization ', Molecular Therapy, vol. 25, no. 8, pp. 1946-1958 . https://doi.org/10.1016/j.ymthe.2017.04.024Test
Molecular Therapy, 25(8), 1946-1958. Nature Publishing Group
Molecular Therapy

مصطلحات موضوعية: 0301 basic medicine, Recombinant Fusion Proteins, medicine.medical_treatment, Antibody Affinity, Receptors, Antigen, T-Cell, CD38, Lymphocyte Activation, Immunoglobulin light chain, Immunotherapy, Adoptive, Mice, 03 medical and health sciences, Antigen, Drug Discovery, Genetics, medicine, Animals, Humans, Cytotoxic T cell, Cytotoxicity, Molecular Biology, Pharmacology, biology, ADP-ribosyl Cyclase 1, Xenograft Model Antitumor Assays, Molecular biology, Chimeric antigen receptor, 3. Good health, Cell biology, Disease Models, Animal, 030104 developmental biology, Cytokine, biology.protein, Cytokines, Molecular Medicine, Original Article, Antibody, Multiple Myeloma, Protein Binding, Single-Chain Antibodies, T-Lymphocytes, Cytotoxic

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b03019c9f7a08f489674beec0fd85b3Test
https://doi.org/10.1016/j.ymthe.2017.04.024Test

المؤلفون: Regina de Jong-Korlaar, Anton C.M. Martens, Joost D. de Bruijn, Ruud W.J. Ruiter, Jyoti Naik, Richard W.J. Groen, Pino J. Poddighe, Huipin Yuan, Niels W.C.J. van de Donk, Gert J. Ossenkoppele, Maria Themeli, Sonja Zweegman, Linda Smit, Tuna Mutis

المساهمون: VU University medical center, Hematology laboratory, CCA - Cancer biology and immunology, AII - Cancer immunology, Human genetics, Hematology

المصدر: Haematologica, 104(3), e100-e103. Ferrata Storti Foundation
Naik, J, Themeli, M, de Jong-Korlaar, R, Ruiter, R W J, Poddighe, P J, Yuan, H, de Bruijn, J D, Ossenkoppele, G J, Zweegman, S, Smit, L, Mutis, T, Martens, A C M, van de Donk, N W C J & Groen, R W J 2019, ' CD38 as a therapeutic target for adult acute myeloid leukemia and T-cell acute lymphoblastic leukemia ', Haematologica, vol. 104, no. 3, pp. e100-e103 . https://doi.org/10.3324/haematol.2018.192757Test

مصطلحات موضوعية: Adult, Male, Myeloid, Antineoplastic Agents, CD38, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Medicine, Humans, Molecular Targeted Therapy, Online Only Articles, neoplasms, Acute leukemia, Membrane Glycoproteins, business.industry, Myeloid leukemia, Adult Acute Myeloid Leukemia, Hematology, medicine.disease, ADP-ribosyl Cyclase 1, Leukemia, Haematopoiesis, Leukemia, Myeloid, Acute, medicine.anatomical_structure, Treatment Outcome, Cancer research, Female, Bone marrow, business, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fe9a9250bcc439c5f5daecb96e6859dTest
https://research.vumc.nl/en/publications/3c8b5f25-1305-4d6f-a88e-856d787ba37cTest

المؤلفون: Anton C.M. Martens, Willy A. Noort, Joost M. Bakker, Tuna Mutis, Paul W. H. I. Parren, Berris van Kessel, Inger S. Nijhof, Jeroen J. Lammerts van Bueren, Richard W.J. Groen, Regina de Jong-Korlaar, Niels W.C.J. van de Donk, Henk M. Lokhorst

المساهمون: Hematology laboratory, Hematology, CCA - Innovative therapy

المصدر: Clinical Cancer Research, 21(12), 2802-2810. American Association for Cancer Research Inc.
Nijhof, I S, Groen, R W J, Noort, W A, van Kessel, B, de Jong-Korlaar, R, Bakker, J, van Bueren, J J L, Parren, P W H I, Lokhorst, H M, van de Donk, N W C J, Martens, A C M & Mutis, T 2015, ' Preclinical Evidence for the Therapeutic Potential of CD38-Targeted Immuno-Chemotherapy in Multiple Myeloma Patients Refractory to Lenalidomide and Bortezomib ', Clinical Cancer Research, vol. 21, no. 12, pp. 2802-2810 . https://doi.org/10.1158/1078-0432.CCR-14-1813Test
Nijhof, I S, Groen, R W J, Noort, W A, van Kessel, B, de Jong-Korlaar, R, Bakker, J, van Bueren, J J L, Parren, P W H I, Lokhorst, H M, van de Donk, N, Martens, A C M & Mutis, T 2015, ' Preclinical Evidence for the Therapeutic Potential of CD38-Targeted Immuno-Chemotherapy in Multiple Myeloma Patients Refractory to Lenalidomide and Bortezomib ', Clinical Cancer Research, vol. 21, no. 12, pp. 2802-2810 . https://doi.org/10.1158/1078-0432.CCR-14-1813Test

مصطلحات موضوعية: Male, Cancer Research, medicine.medical_treatment, Drug Evaluation, Preclinical, Antibody-Dependent Cell Cytotoxicity/immunology, Pharmacology, Lymphocyte Activation, Bortezomib, Mice, immune system diseases, hemic and lymphatic diseases, ADP-ribosyl Cyclase 1/antagonists & inhibitors, Molecular Targeted Therapy, Lenalidomide, Multiple myeloma, Killer Cells, Natural/drug effects, Isatuximab, Drug Synergism, Middle Aged, Lymphocyte Activation/drug effects, Thalidomide, Killer Cells, Natural, medicine.anatomical_structure, Oncology, Female, Immunotherapy, Multiple Myeloma, medicine.drug, Adult, Cell Line, Tumor, medicine, Animals, Humans, Multiple Myeloma/diagnosis, Aged, Thalidomide/administration & dosage, business.industry, Antibody-Dependent Cell Cytotoxicity, Daratumumab, NATURAL-KILLER-CELLS APOPTOSIS-INDUCING LIGAND PROTEASOME INHIBITION ANTIBODY DARATUMUMAB CYTOTOXICITY COMBINATION ELOTUZUMAB MULTICENTER THALIDOMIDE EXPRESSION, medicine.disease, ADP-ribosyl Cyclase 1, Xenograft Model Antitumor Assays, Disease Models, Animal, Cancer research, Bortezomib/administration & dosage, Bone marrow, business, Ex vivo

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc002482a8f6d680034431f465f4cc8Test
https://doi.org/10.1158/1078-0432.ccr-14-1813Test

المؤلفون: Anton C. M. Martens, Gert J. Ossenkoppele, Willy A. Noort, Jan Jacob Schuringa, Jenny Jaques, Antonella Antonelli, Andries C. Bloem, Annet Z. Brouwers-Vos, Regina de Jong-Korlaar, Joost D. de Bruijn, Jeroen F. van Velzen, Edo Vellenga, Linda Lubbers-Aalders, Huipin Yuan, Richard W.J. Groen, Bauke de Boer

المساهمون: Stem Cell Aging Leukemia and Lymphoma (SALL), Guided Treatment in Optimal Selected Cancer Patients (GUTS), CCA - Cancer biology, Hematology, Hematology laboratory

المصدر: Blood, 128(25), 2949-2959. AMER SOC HEMATOLOGY
Blood, 128(25), 2949-2959. American Society of Hematology
Antonelli, A, Noort, W A, Jaques, J, de Boer, B, de Jong-Korlaar, R, Brouwers-Vos, A Z, Lubbers-Aalders, L, van Velzen, J F, Bloem, A C, Yuan, H, de Bruijn, J D, Ossenkoppele, G J, Martens, A C M, Vellenga, E, Groen, R W J & Schuringa, J J 2016, ' Establishing human leukemia xenograft mouse models by implanting human bone marrow-like scaffold-based niches ', Blood, vol. 128, no. 25, pp. 2949-2959 . https://doi.org/10.1182/blood-2016-05-719021Test, https://doi.org/10.1182/blood-2016-05719021Test

مصطلحات موضوعية: 0301 basic medicine, Pathology, Myeloid, Cell Separation, Biochemistry, Transcriptome, Mice, Bone Marrow, Cell Self Renewal, Stem Cell Niche, Tissue Scaffolds, Gene Expression Regulation, Leukemic, Hematology, Haematopoiesis, Leukemia, Leukemia, Myeloid, Acute, medicine.anatomical_structure, Phenotype, Female, EX-VIVO ASSAYS, Stem cell, STEM-CELLS, IMPROVED ENGRAFTMENT, medicine.medical_specialty, XENOTRANSPLANTATION MODEL, Immunology, ACUTE MYELOID-LEUKEMIA, Biology, 03 medical and health sciences, LONG-TERM EXPANSION, NOD/SCID MICE, medicine, Animals, Humans, HUMAN HEMATOPOIETIC-CELLS, Gene Expression Profiling, Mesenchymal stem cell, Mesenchymal Stem Cells, Cell Biology, medicine.disease, Hematopoietic Stem Cells, Xenograft Model Antitumor Assays, Clone Cells, Transplantation, SELF-RENEWAL, 030104 developmental biology, Cancer research, Bone marrow, Stromal Cells, MLL-AF9 LEUKEMIA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f6e65245bc5af4d6523afc0239c8190Test
https://research.rug.nl/en/publications/5788e57c-1b76-4d71-b7b5-a42955af59bbTest

المؤلفون: Joost D. de Bruijn, Richard W.J. Groen, Anton C.M. Martens, Willy A. Noort, Huipin Yuan, Regina de Jong-Korlaar, Constantine S. Mitsiades, Linda Lubbers-Aalders

المساهمون: CCA - Innovative therapy, Hematology laboratory, CCA - Quality of life

المصدر: Blood, 126(23). American Society of Hematology
Noort, W A, de Jong-Korlaar, R, Lubbers-Aalders, L, Yuan, H, de Bruijn, J D, Mitsiades, C S, Martens, A C M & Groen, R W J 2015, ' Addition of the Vascular Niche Component to the Human Bone Marrow-like Scaffold Model ', Blood, vol. 126, no. 23 .

مصطلحات موضوعية: Matrigel, Stromal cell, Chemistry, Xenotransplantation, medicine.medical_treatment, Immunology, Mesenchymal stem cell, Cell Biology, Hematology, medicine.disease, Biochemistry, Cell biology, Leukemia, Haematopoiesis, medicine, CD146, Progenitor cell

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530b33dff8ae2b201ec80406f2e832aaTest
https://research.vumc.nl/en/publications/d6ef8959-e9a6-49f0-bc48-eb4cd1e6de1fTest

المؤلفون: Marion Scharpfenecker, Regina de Jong-Korlaar, Fiona A. Stewart, Erik van Werkhoven, B.G.J. Floot, Leonie A. E. Woerdeman, Nicola S. Russell, Mitchel Schriemer

المصدر: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology. 116(3)

مصطلحات موضوعية: Adult, Pathology, medicine.medical_specialty, Biopsy, Blotting, Western, Human skin, Breast Neoplasms, Receptors, Cell Surface, Lymphatic System, Antigens, CD, Transforming Growth Factor beta, TGF beta signaling pathway, medicine, Humans, Radiology, Nuclear Medicine and imaging, Phosphorylation, Radiation Injuries, Microvessel, Aged, Skin, biology, business.industry, Macrophages, Endoglin, Hematology, Transforming growth factor beta, Middle Aged, Immunohistochemistry, Lymphatic system, medicine.anatomical_structure, Oncology, Microvessels, biology.protein, Female, business, Receptors, Transforming Growth Factor beta, Transforming growth factor, Blood vessel, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b852fed6338120b5b81ddc34fc5febbcTest
https://pubmed.ncbi.nlm.nih.gov/26347496Test