دورية أكاديمية
Association between circadian physical activity patterns and mortality in the UK Biobank
| العنوان: | Association between circadian physical activity patterns and mortality in the UK Biobank |
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| المؤلفون: | Michael J. Stein, Hansjörg Baurecht, Anja M. Sedlmeier, Julian Konzok, Patricia Bohmann, Emma Fontvieille, Laia Peruchet-Noray, Jack Bowden, Christine M. Friedenreich, Béatrice Fervers, Pietro Ferrari, Marc J. Gunter, Heinz Freisling, Michael F. Leitzmann, Vivian Viallon, Andrea Weber |
| المصدر: | International Journal of Behavioral Nutrition and Physical Activity, Vol 20, Iss 1, Pp 1-9 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Nutritional diseases. Deficiency diseases LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Physical activity patterns, All-cause mortality, UK Biobank, Raw accelerometry, Nutritional diseases. Deficiency diseases, RC620-627, Public aspects of medicine, RA1-1270 |
| الوصف: | Abstract Background The benefit of physical activity (PA) for increasing longevity is well-established, however, the impact of diurnal timing of PA on mortality remains poorly understood. We aimed to derive circadian PA patterns and investigate their associations with all-cause mortality. Methods We used 24 h PA time series from 96,351 UK Biobank participants aged between 42 and 79 years at accelerometry in 2013–2015. Functional principal component analysis (fPCA) was applied to obtain circadian PA patterns. Using multivariable Cox proportional hazard models, we related the loading scores of these fPCs to estimate risk of mortality. Results During 6.9 years of follow-up, 2,850 deaths occurred. Four distinct fPCs accounted for 96% of the variation of the accelerometry data. Using a loading score of zero (i.e., average overall PA during the day) as the reference, a fPC1 score of + 2 (high overall PA) was inversely associated with mortality (Hazard ratio, HR = 0.91; 95% CI: 0.84–0.99), whereas a score of -2 (low overall PA) was associated with higher mortality (1.69; 95% CI: 1.57–1.81; p for non-linearity |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1479-5868 |
| العلاقة: | https://doaj.org/toc/1479-5868Test |
| DOI: | 10.1186/s12966-023-01508-z |
| الوصول الحر: | https://doaj.org/article/a7efca6f0f0449ae9110da037d34a777Test |
| رقم الانضمام: | edsdoj.7efca6f0f0449ae9110da037d34a777 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14795868 |
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| DOI: | 10.1186/s12966-023-01508-z |