المؤلفون: Thomson, Christopher G., Aicher, Thomas D., Cheng, Weiwei, Du, Hongwen, Dudgeon, Crissy, Li, An-Hu, Li, Baozhong, Lightcap, Eric, Luo, Diheng, Mulvihill, Mark, Pan, Pengwei, Rahemtulla, Benjamin F., Rigby, Alan C., Sherborne, Bradley, Sood, Sanjeev, Surguladze, David, Talbot, Eric P. A., Tameire, Feven, Taylor, Simon, Wang, Yi, Wojnarowicz, Paulina, Xiao, Fenfen, Ramurthy, Savithri

المساهمون: HiberCell Inc.

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 7, page 5259-5271 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.3c02384Test

المؤلفون: Miethke, Marcus, Pieroni, Marco, Weber, Tilmann, Brönstrup, Mark, Hammann, Peter, Halby, Ludovic, Arimondo, Paola B., Glaser, Philippe, Aigle, Bertrand, Bode, Helge, B., Moreira, Rui, Li, Yanyan, Luzhetskyy, Andriy, Medema, Marnix, H., Pernodet, Jean-Luc, Stadler, Marc, Tormo, José Rubén, Genilloud, Olga, Truman, Andrew, W., Weissman, Kira J., Takano, Eriko, Sabatini, Stefano, Stegmann, Evi, Brötz-Oesterhelt, Heike, Wohlleben, Wolfgang, Seemann, Myriam, Empting, Martin, Hirsch, Anna, K. H., Loretz, Brigitta, Lehr, Claus-Michael, Titz, Alexander, Herrmann, Jennifer, Jaeger, Timo, Alt, Silke, Hesterkamp, Thomas, Winterhalter, Mathias, Schiefer, Andrea, Pfarr, Kenneth, Hoerauf, Achim, Graz, Heather, Graz, Michael, Lindvall, Mika, Ramurthy, Savithri, Karlén, Anders, van Dongen, Maarten, Petkovic, Hrvoje, Keller, Andreas, Peyrane, Frédéric, Donadio, Stefano, Fraisse, Laurent, Piddock, Laura, J. V., Gilbert, Ian, H., Moser, Heinz, E., Müller, Rolf

المساهمون: Helmholtz-Zentrum für Infektionsforschung GmbH (HZI), Universität des Saarlandes Saarbrücken, German Centre for Infection Research (DZIF), Università degli studi di Parma = University of Parma (UNIPR), Danmarks Tekniske Universitet = Technical University of Denmark (DTU), Justus-Liebig-Universität Gießen = Justus Liebig University (JLU), Chimie biologique épigénétique - Epigenetic Chemical Biology (EpiCBio), Institut Pasteur Paris (IP)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Écologie et Évolution de la Résistance aux Antibiotiques / Ecology and Evolution of Antibiotics Resistance (EERA), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Saclay-Université Paris Cité (UPCité)-Microbiologie Intégrative et Moléculaire (UMR6047), Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS)-Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Dynamique des Génomes et Adaptation Microbienne (DynAMic), Université de Lorraine (UL)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Goethe-Universität Frankfurt am Main, Max Planck Institute for Terrestrial Microbiology, Max-Planck-Gesellschaft, Universidade de Lisboa = University of Lisbon = Université de Lisbonne (ULISBOA), Molécules de Communication et Adaptation des Micro-organismes (MCAM), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS), Wageningen University and Research Wageningen (WUR), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Fundación MEDINA Granada, John Innes Centre Norwich, Biotechnology and Biological Sciences Research Council (BBSRC), Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), University of Manchester Manchester, Università degli Studi di Perugia = University of Perugia (UNIPG), Eberhard Karls Universität Tübingen = University of Tübingen, Institut de Chimie de Strasbourg (IC), Université de Strasbourg (UNISTRA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Jacobs University = Constructor University Bremen, University Hospital Bonn, Biophys Usk, UK, University of Bristol Bristol, Recursion Salt Lake City, UT, HiberCell New York, Uppsala Universitet Uppsala, AMR Insights, University of Ljubljana, BEAM Alliance, Naicons, Drugs for Neglected Diseases Initiative, Global Antibiotic Research and Development Partnership Geneva, Switzerland (GARDP), University of Dundee, Novartis Institutes for BioMedical Research (NIBR), The project on PqsR pathoblocker development acknowledges funding through the German Center for Infection Research (DZIF, projects TTU09.908 and TTU09.916), the Helmholtz Association (Helmholtz Validation Fund) and additional contributions by the associated academic institutes (HZI and HIPS). The development of chelocardins is supported by the DZIF (TTU09.814/09.821), the Helmholtz Innovation Fund (Pre-4D), by the Slovenian Research Agency, ARRS, grant no. J4-8226, and in collaboration with AciesBio, Slovenia. The corallopyronin project is funded by the DZIF (TTU09.807/09.816, TTU09.914), the German Federal Ministry of Education and Research (BMBF), the federal state of North Rhine-Westphalia (EFRE.NRW) and EU Horizon 2020. Eriko Takano was funded by the European Union’s Horizon 2020 research and innovation programme under grant agreement no. 720793 “TOPCAPI: Thoroughly Optimised Production Chassis for Advanced Pharmaceutical Ingredients”., European Project: 720793,H2020-EU.2.1.4.,TOPCAPI(2017)

المصدر: ISSN: 2397-3358.

مصطلحات موضوعية: Business strategy in drug development, Drug therapy, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34426795; info:eu-repo/grantAgreement//720793/EU/Thoroughly Optimised Production Chassis for Advanced Pharmaceutical Ingredients/TOPCAPI; pasteur-03427787; https://pasteur.hal.science/pasteur-03427787Test; https://pasteur.hal.science/pasteur-03427787/documentTest; https://pasteur.hal.science/pasteur-03427787/file/Miethke%20et%20al._Nat%20Rev%20Chem_revision_21-04-12._cleanup.pdfTest; PUBMED: 34426795; PUBMEDCENTRAL: PMC8374425; WOS: 000686482900001

الإتاحة: https://doi.org/10.1038/s41570-021-00313-1Test
https://pasteur.hal.science/pasteur-03427787Test
https://pasteur.hal.science/pasteur-03427787/documentTest
https://pasteur.hal.science/pasteur-03427787/file/Miethke%20et%20al._Nat%20Rev%20Chem_revision_21-04-12._cleanup.pdfTest

المؤلفون: Ramurthy, Savithri, Taft, Benjamin R., Aversa, Robert J., Barsanti, Paul A., Burger, Matthew T., Lou, Yan, Nishiguchi, Gisele A., Rico, Alice, Setti, Lina, Smith, Aaron, Subramanian, Sharadha, Tamez, Victoriano, Tanner, Huw, Wan, Lifeng, Hu, Cheng, Appleton, Brent A., Mamo, Mulugeta, Tandeske, Laura, Tellew, John E., Huang, Shenlin, Yue, Qin, Chaudhary, Apurva, Tian, Hung, Iyer, Raman, Hassan, A. Quamrul, Mathews Griner, Lesley A., La Bonte, Laura R., Cooke, Vesselina G., Van Abbema, Anne, Merritt, Hanne, Gampa, Kalyani, Feng, Fei, Yuan, Jing, Mishina, Yuji, Wang, Yingyun, Haling, Jacob R., Vaziri, Sepideh, Hekmat-Nejad, Mohammad, Polyakov, Valery, Zang, Richard, Sethuraman, Vijay, Amiri, Payman, Singh, Mallika, Sellers, William R., Lees, Emma, Shao, Wenlin, Dillon, Michael P., Stuart, Darrin D.

المصدر: Journal of Medicinal Chemistry ; volume 63, issue 5, page 2013-2027 ; ISSN 0022-2623 1520-4804

الإتاحة: https://doi.org/10.1021/acs.jmedchem.9b00161Test

المؤلفون: Jansen, Johanna M., Wartchow, Charles, Jahnke, Wolfgang, Fong, Susan, Tsang, Tiffany, Zavorotinskaya, Tatiana, Bussiere, Dirksen, Cheng, Jan Marie, Crawford, Kenneth, Dai, Yumin, Dove, Jeffrey, Fang, Eric, Feng, Yun, Florent, Jean-Michel, Fuller, John, Gossert, Alvar Diego, id_orcid:0 000-0001-7732-495X, Hekmat-Nejad, Mohammad, Henry, Chrystèle, Klopp, Julia, Lenahan, William P., Lingel, Andreas, Ma, Sylvia, Meyer, Arndt, Mishina, Yuji, Narberes, Jamie, Pardee, Gwynn, Ramurthy, Savithri, Rieffel, Sebastien, Stuart, Darrin, Subramanian, Sharadha, Tandeske, Laura, Widger, Stephania, Widmer, Armin, Winterhalter, Aurelie, Zaror, Isabel, Hardy, Stephen

المصدر: PLoS ONE, 12 (4)

وصف الملف: application/application/pdf

العلاقة: http://hdl.handle.net/20.500.11850/362530Test

الإتاحة: https://doi.org/20.500.11850/362530Test
https://doi.org/10.3929/ethz-b-000362530Test
https://doi.org/10.1371/journal.pone.0174706Test
https://hdl.handle.net/20.500.11850/362530Test

المؤلفون: Miethke, Marcus, Pieroni, Marco, Weber, Tilmann, Brönstrup, Mark, Hammann, Peter, Halby, Ludovic, Arimondo, Paola, GLASER, Philippe, Aigle, Bertrand, Bode, Helge, Moreira, Rui, Li, Yanyan, Luzhetskyy, Andriy, Medema, Marnix, Pernodet, Jean-Luc, Stadler, Marc, Tormo, José Rubén, Genilloud, Olga, Truman, Andrew, Weissman, Kira, Takano, Eriko, Sabatini, Stefano, Stegmann, Evi, Brötz-Oesterhelt, Heike, Wohlleben, Wolfgang, Seemann, Myriam, Empting, Martin, Hirsch, Anna, Loretz, Brigitta, Lehr, Claus-Michael, Titz, Alexander, Herrmann, Jennifer, Jaeger, Timo, Alt, Silke, Hesterkamp, Thomas, Winterhalter, Mathias, Schiefer, Andrea, Pfarr, Kenneth, Hoerauf, Achim, Graz, Heather, Graz, Michael, Lindvall, Mika, Ramurthy, Savithri, Karlén, Anders, van Dongen, Maarten, Petkovic, Hrvoje, Keller, Andreas, Peyrane, Frédéric, Donadio, Stefano, Fraisse, Laurent, Piddock, Laura, Gilbert, Ian, Moser, Heinz, Müller, Rolf

المساهمون: Molécules de Communication et Adaptation des Micro-organismes (MCAM), Muséum national d'Histoire naturelle (MNHN)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 2397-3358.

مصطلحات موضوعية: [CHIM]Chemical Sciences

العلاقة: hal-03455640; https://hal.archives-ouvertes.fr/hal-03455640Test

الإتاحة: https://doi.org/10.1038/s41570-021-00313-1Test
https://hal.archives-ouvertes.fr/hal-03455640Test

المؤلفون: Subramanian, Sharadha, Costales, Abran, Williams, Teresa E., Levine, Barry, McBride, Christopher M., Poon, Daniel, Amiri, Payman, Renhowe, Paul A., Shafer, Cynthia M., Stuart, Darrin, Verhagen, Joelle, Ramurthy, Savithri

المصدر: ACS Medicinal Chemistry Letters ; volume 5, issue 12, page 1340-1340 ; ISSN 1948-5875 1948-5875

مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry

الإتاحة: https://doi.org/10.1021/ml500461gTest