المؤلفون: Calheiros, Juliana¹ (AUTHOR) julianameixedo@ua.pt, Raimundo, Liliana¹ (AUTHOR) liliana-raimundo@live.com, Morais, João¹ (AUTHOR) up201805193@edu.fc.up.pt, Matos, Ana Catarina¹ (AUTHOR) catarina.matos99@hotmail.com, Minuzzo, Sonia Anna² (AUTHOR) soniaanna.minuzzo@unipd.it, Indraccolo, Stefano^2,3 (AUTHOR) stefano.indraccolo@unipd.it, Sousa, Emília^4,5 (AUTHOR) esousa@ff.up.pt, Silva, Marta Correia da^4,5 (AUTHOR) m_correiadasilva@ff.up.pt, Saraiva, Lucília¹ (AUTHOR) lucilia.saraiva@ff.up.pt

المصدر: Cancers. Dec2023, Vol. 15 Issue 24, p5718. 16p.

مصطلحات موضوعية: *PANCREATIC tumors, *ADENOCARCINOMA, *FLOW cytometry, *WOUND healing, *STATISTICS, *BIOLOGICAL models, *OVARIAN tumors, *ANALYSIS of variance, *NUCLEOSIDES, *COLONY-forming units assay, *WESTERN immunoblotting, *ANTINEOPLASTIC agents, *METASTASIS, *APOPTOSIS, *DUCTAL carcinoma, *CELL survival, *CELL cycle, *DESCRIPTIVE statistics, *CELL proliferation, *RESEARCH funding, *CELL lines, *TUMORS, *MOLECULAR structure, *DATA analysis software, *DATA analysis, *BREAST tumors, *PHARMACODYNAMICS, BREAST cancer chemotherapy

المؤلفون: Cerqueira, Fátima, Maia, Marta, Gabriel, Carla, Medeiros, Rui, Cravo, Sara, Ribeiro, Ana Isabel, Dantas, Daniela, Dias, Alice Maria, Saraiva, Lucília, Raimundo, Liliana, Pinto, Eugénia

مصطلحات موضوعية: Candida sp, antifungals, (Z)-5-amino-N’, aryl-1-methyl-1H-imidazole-4-carbohydrazonamides, mechanisms of action, reactive oxygen species, ergosterol, dimorphic transition, metabolic viability, (Z)-5-amino-N’-aryl-1-methyl-1H-imidazole-4-carbohydrazonamides, Science & Technology

وصف الملف: application/pdf

العلاقة: UID/Multi/04546/2019; UIDB/04423/2020; UIDB/50006/2020; UID/QUI/00686/2020; https://www.mdpi.com/2079-6382/10/2/183Test; Cerqueira, F.; Maia, M.; Gabriel, C.; Medeiros, R.; Cravo, S.; Ribeiro, A.I.; Dantas, D.; Dias, A.M.; Saraiva, L.; Raimundo, L.; Pinto, E. Mechanism of Antifungal Activity by 5-Aminoimidazole-4-Carbohydrazonamide Derivatives against Candida albicans and Candida krusei. Antibiotics 2021, 10, 183. https://doi.org/10.3390/antibiotics10020183Test; http://hdl.handle.net/1822/72539Test

الإتاحة: https://doi.org/10.3390/antibiotics10020183Test
http://hdl.handle.net/1822/72539Test

المؤلفون: Ramos, Helena, Soares, Maria I. L., Silva, Joana, Raimundo, Liliana, Calheiros, Juliana, Gomes, Célia, Reis, Flávio, Monteiro, Filipe A., Nunes, Cláudia, Reis, Salette, Bosco, Bartolomeo, Piazza, Silvano, Domingues, Lucília, Chlapek, Petr, Vlcek, Petr, Fabian, Pavel, Rajado, Ana Teresa, Carvalho, A. T. P., Veselska, Renata, Inga, Alberto, Pinho e Melo, Teresa M. V. D., Saraiva, Lucília

مصطلحات موضوعية: p53 activator, Anticancer drug, Colorectal cancer, Targeted therapy, Science & Technology

وصف الملف: application/pdf

العلاقة: UIDB/50006/2020; UID/BIO/04469/2019; UIDB/04539/2020; UIDP/04539/2020; SFRH/BD/119144/2016; SFRH/BD/117949/2016; UIDB/00313/2020; UIDP/00313/2020; https://www.sciencedirect.com/journal/cell-reportsTest; Ramos, Helena; Soares, Maria I. L.; Silva, Joana; Raimundo, Liliana; Calheiros, Juliana; Gomes, Célia; Reis, Flávio; Monteiro, Filipe A.; Nunes, Cláudia; Reis, Salette; Bosco, Bartolomeo; Piazza, Silvano; Domingues, Lucília; Chlapek, Petr; Vlcek, Petr; Fabian, Pavel; Rajado, Ana Teresa; Carvalho, A. T. P.; Veselska, Renata; Inga, Alberto; Melo, Teresa M. V. D. Pinho e; Saraiva, Lucília, A selective p53 activator and anticancer agent to improve colorectal cancer therapy. Cell Reports, 35(2), 108982, 2021; http://hdl.handle.net/1822/72078Test

الإتاحة: https://doi.org/10.1016/j.celrep.2021.108982Test
http://hdl.handle.net/1822/72078Test

المؤلفون: Loureiro, Joana B., Raimundo, Liliana, Calheiros, Juliana, Carvalho, Carla, Barcherini, Valentina, Lima, Nuno R., Gomes, Célia, Almeida, Maria Inês, Alves, Marco G., Costa, José Luís, Santos, Maria M. M., Saraiva, Lucília

مصطلحات موضوعية: Melanoma, Metastasis, Drug resistance, Targeted therapy, p53, Tryptophanol-derived oxazoloisoindolinone

وصف الملف: application/pdf

العلاقة: UID/QUI/50006/2020; UIDB/04138/2020; PTDC/QUIQOR/29664/2017; PTDC/MEC-ONC/32018/2017; SFRH/BD/128673/2017; PD/BD/143126/2019; https://www.mdpi.com/2072-6694/13/7/1648Test; Loureiro, J.B.; Raimundo, L.; Calheiros, J.; Carvalho, C.; Barcherini, V.; Lima, N.R.; Gomes, C.; Almeida, M.I.; Alves, M.G.; Costa, J.L.; Santos, M.M.M.; Saraiva, L. Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance. Cancers 2021, 13, 1648. https://doi.org/10.3390/cancers13071648Test; http://hdl.handle.net/1822/73358Test

الإتاحة: https://doi.org/10.3390/cancers13071648Test
http://hdl.handle.net/1822/73358Test

المؤلفون: Gomes, Sara, Bosco, Bartolomeo, Loureiro, Joana B, Ramos, Helena, Raimundo, Liliana, Soares, Joana, Nazareth, Nair, Barcherini, Valentina, Domingues, Lucília, Oliveira, Carla, Bisio, Alessandra, Piazza, Silvano, Bauer, Matthias R, Brás, João P, Almeida, Maria Inês, Gomes, Célia, Reis, Flávio, Fersht, Alan R, Inga, Alberto, Santos, Maria M M, Saraiva, Lucília

المساهمون: Gomes, Sara, Bosco, Bartolomeo, Loureiro, Joana B, Ramos, Helena, Raimundo, Liliana, Soares, Joana, Nazareth, Nair, Barcherini, Valentina, Domingues, Lucília, Oliveira, Carla, Bisio, Alessandra, Piazza, Silvano, Bauer, Matthias R, Brás, João P, Almeida, Maria Inê, Gomes, Célia, Reis, Flávio, Fersht, Alan R, Inga, Alberto, Santos, Maria M M, Saraiva, Lucília

مصطلحات موضوعية: Hsp70, anticancer therapeutic, hepatocellular carcinoma, mutant p53, tryptophanol-derived oxazoloisoindolinone

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/31405179; info:eu-repo/semantics/altIdentifier/wos/WOS:000484438000111; volume:11; issue:8; firstpage:1151; journal:CANCERS; http://hdl.handle.net/11572/241142Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85073295665

الإتاحة: https://doi.org/10.3390/cancers11081151Test
http://hdl.handle.net/11572/241142Test

المؤلفون: Pereira, Daniela, Lima, Raquel T., Palmeira, Andreia, Seca, Hugo, Soares, Joana, Gomes, Sara, Raimundo, Liliana, Maciel, Claudia, Pinto, Madalena, Sousa, Emília, Helena Vasconcelos, M., Saraiva, Lucília, Cidade, Honorina

المصدر: Pereira , D , Lima , R T , Palmeira , A , Seca , H , Soares , J , Gomes , S , Raimundo , L , Maciel , C , Pinto , M , Sousa , E , Helena Vasconcelos , M , Saraiva , L & Cidade , H 2019 , ' Design and synthesis of new inhibitors of p53–MDM2 interaction with a chalcone scaffold ' , Arabian Journal of Chemistry , vol. 12 , no. 8 , pp. 4150-4161 . https://doi.org/10.1016/j.arabjc.2016.04.015Test

مصطلحات موضوعية: Chalcones, Docking, In vitro antitumor activity, p53–MDM2 interaction inhibitors, /dk/atira/pure/subjectarea/asjc/1600/1600, name=General Chemistry, /dk/atira/pure/subjectarea/asjc/1500/1500, name=General Chemical Engineering

وصف الملف: application/pdf

العلاقة: https://discovery.dundee.ac.uk/en/publications/f060e51c-f673-46ab-aa83-1cec172d9ea3Test

الإتاحة: https://doi.org/10.1016/j.arabjc.2016.04.015Test
https://discovery.dundee.ac.uk/en/publications/f060e51c-f673-46ab-aa83-1cec172d9ea3Test
https://discovery.dundee.ac.uk/ws/files/48903138/1_s2.0_S1878535216300399_main.pdfTest
http://www.scopus.com/inward/record.url?scp=85014742778&partnerID=8YFLogxKTest

المؤلفون: Soares, Joana, Espadinha, Margarida, Raimundo, Liliana, Ramos, Helena, Gomes, Ana Sara, Gomes, Sara, Loureiro, Joana B, Inga, Alberto, Reis, Flávio, Gomes, Célia, Santos, Maria M. M, Saraiva, Lucília

المساهمون: Soares, Joana, Espadinha, Margarida, Raimundo, Liliana, Ramos, Helena, Gomes, Ana Sara, Gomes, Sara, Loureiro, Joana B, Inga, Alberto, Reis, Flávio, Gomes, Célia, Santos, Maria M. M, Saraiva, Lucília

مصطلحات موضوعية: MDMX, MDM2, anticancer therapy, p53, small-molecule, tryptophanol-derived oxazoloisoindolinone

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28296148; info:eu-repo/semantics/altIdentifier/wos/WOS:000405741400002; volume:2017; journal:MOLECULAR ONCOLOGY; http://hdl.handle.net/11572/174420Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85025616812

الإتاحة: https://doi.org/10.1002/1878-0261.12051Test
http://hdl.handle.net/11572/174420Test

المؤلفون: Bessa, Cláudia, Soares, Joana, Raimundo, Liliana, Loureiro, Joana B., Gomes, Célia, Reis, Flávio, Soares, Miguel L., Santos, Daniel, Dureja, Chetna, Chaudhuri, Saumya R., Lopez-Haber, Cynthia, Kazanietz, Marcelo G., Gonçalves, Jorge, Simões, Maria F., Rijo, Patrícia, Saraiva, Lucília

مصطلحات موضوعية: Colonic Neoplasms, Humans, Protein Kinase C-delta

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; POCI/01/0145/FEDER/007728; FCOMP-01-0124-FEDER-028417; POCI-01-0145-FEDER-007440; UID/MULTI/04378/2013; UID/DTP/04567/2016; PT2020UID/NEU/04539/2013; ENTRO-01-0145- FEDER-000012; SFRH/BD/87109/2012; SFRH/BD/117949/2016; https://hdl.handle.net/10316/107532Test

الإتاحة: https://doi.org/10.1038/s41419-017-0154-9Test
https://hdl.handle.net/10316/107532Test

المؤلفون: Facioni, Maria Sole, Soares, Joana, Adinolfi, Barabara, Gomes, Sara, Raimundo, Liliana, Contini, Adele, Ruffoni, Barbara, Azzarà, Alessia, Tavanti, Arianna, Bertoli, Alessandra, Pistelli, Luisa, Saraiva, Lucilia, Scarpato, Roberto

المصدر: Facioni , M S , Soares , J , Adinolfi , B , Gomes , S , Raimundo , L , Contini , A , Ruffoni , B , Azzarà , A , Tavanti , A , Bertoli , A , Pistelli , L , Saraiva , L & Scarpato , R 2018 , ' Biological effects of saponin fractions from Astragalus verrucosus in tumor and non-tumor human cells ' , Natural Product Communications , vol. 13 , no. 9 , pp. 1105-1110 . https://doi.org/10.1177/1934578X1801300903Test

مصطلحات موضوعية: Apoptosis, Cytotoxicity, Genotoxicity, Human lymphocytes, Saponin fractions, Tumor cells, /dk/atira/pure/subjectarea/asjc/3000/3004, name=Pharmacology, /dk/atira/pure/subjectarea/asjc/1100/1110, name=Plant Science, /dk/atira/pure/subjectarea/asjc/3000/3002, name=Drug Discovery, /dk/atira/pure/subjectarea/asjc/2700/2707, name=Complementary and alternative medicine

العلاقة: https://discovery.dundee.ac.uk/en/publications/a0b607ca-331a-46fe-8a79-f8af4b27b554Test

الإتاحة: https://doi.org/10.1177/1934578X1801300903Test
https://discovery.dundee.ac.uk/en/publications/a0b607ca-331a-46fe-8a79-f8af4b27b554Test
http://www.scopus.com/inward/record.url?scp=85053230833&partnerID=8YFLogxKTest

المؤلفون: Raimundo, Liliana, Espadinha, Margarida, Soares, Joana, Loureiro, Joana B, Alves, Marco G, Santos, Maria M M, Saraiva, Lucília

المساهمون: Fundação para a Ciência e a Tecnologia

المصدر: British Journal of Pharmacology ; volume 175, issue 20, page 3947-3962 ; ISSN 0007-1188 1476-5381

الإتاحة: https://doi.org/10.1111/bph.14468Test