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1دورية أكاديمية
المؤلفون: Randa El-Gamal, Sara Elfarrash, Mohammad EL-Nablaway, Asmaa Ahmed Salem, Seyed-Omar Zaraei, Hanan S. Anbar, Ashraf Shoma, Mohammed I. El-Gamal
المصدر: BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
مصطلحات موضوعية: Breast cancer, MCF-7, Quinoline, Anticancer drugs, Raf kinases, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1471-2407Test
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2دورية أكاديمية
المؤلفون: Bonsor, Daniel, Alexander, Patrick, Snead, Kelly, Hartig, Nicole, Drew, Matthew, Messing, Simon, Finci, Lorenzo, Nissley, Dwight, Esposito, Dominic, Rodriguez-Viciana, Pablo, Stephen, Andrew, Simanshu, Dhirendra, Mccormick, Frank
المصدر: Nature Structural & Molecular Biology. 29(10)
مصطلحات موضوعية: Humans, Intracellular Signaling Peptides and Proteins, MAP Kinase Signaling System, Mitogen-Activated Protein Kinase Kinases, Noonan Syndrome, Phosphoserine, Protein Phosphatase 1, Proto-Oncogene Proteins p21(ras), raf Kinases, ras Proteins
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/4j17m0kcTest
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3دورية أكاديمية
المؤلفون: Kwon, Jason J, Hajian, Behnoush, Bian, Yuemin, Young, Lucy C, Amor, Alvaro J, Fuller, James R, Fraley, Cara V, Sykes, Abbey M, So, Jonathan, Pan, Joshua, Baker, Laura, Lee, Sun Joo, Wheeler, Douglas B, Mayhew, David L, Persky, Nicole S, Yang, Xiaoping, Root, David E, Barsotti, Anthony M, Stamford, Andrew W, Perry, Charles K, Burgin, Alex, McCormick, Frank, Lemke, Christopher T, Hahn, William C, Aguirre, Andrew J
المصدر: Nature. 609(7926)
مصطلحات موضوعية: 2.1 Biological and endogenous factors, Underpinning research, Aetiology, 1.1 Normal biological development and functioning, Generic health relevance, Cancer, Amino Acid Motifs, Binding Sites, Cryoelectron Microscopy, Guanosine Triphosphate, Humans, Intracellular Signaling Peptides and Proteins, MAP Kinase Signaling System, Multiprotein Complexes, Mutation, Missense, Phosphorylation, Protein Binding, Protein Phosphatase 1, Protein Stability, raf Kinases, ras Proteins, General Science & Technology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/4m38t93vTest
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4دورية أكاديمية
المؤلفون: Liau, Nicholas PD, Johnson, Matthew C, Izadi, Saeed, Gerosa, Luca, Hammel, Michal, Bruning, John M, Wendorff, Timothy J, Phung, Wilson, Hymowitz, Sarah G, Sudhamsu, Jawahar
المصدر: Nature. 609(7926)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Generic health relevance, Cryoelectron Microscopy, Guanosine Triphosphate, Humans, Intracellular Signaling Peptides and Proteins, Multiprotein Complexes, Mutation, Phosphoserine, Protein Isoforms, Protein Phosphatase 1, Signal Transduction, Substrate Specificity, raf Kinases, ras Proteins, General Science & Technology
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/2tc1b8cjTest
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5دورية أكاديمية
المؤلفون: Lai, Lick Pui, Fer, Nicole, Burgan, William, Wall, Vanessa E, Xu, Bingfang, Soppet, Daniel, Esposito, Dominic, Nissley, Dwight V, McCormick, Frank
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 119(5)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Biological Sciences, Cancer, Lung, Rare Diseases, Animals, Antineoplastic Agents, Cell Line, Tumor, Cell Proliferation, Fibroblasts, Intracellular Signaling Peptides and Proteins, MAP Kinase Signaling System, Mice, Mouse Embryonic Stem Cells, Mutation, Phosphorylation, Protein Kinase Inhibitors, Proto-Oncogene Proteins B-raf, Proto-Oncogene Proteins c-raf, Signal Transduction, raf Kinases, ras Proteins, MRAS, paradoxical ERK activation, RAF inhibitors, RAS GTPase, RAS-related GTPase
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/5002x1n1Test
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6دورية أكاديمية
المؤلفون: Hwanhee Kim, Soohyun Ko, Byung Ju Kim, Sung Jin Ryu, Jaegyoon Ahn
المصدر: Journal of Cheminformatics, Vol 14, Iss 1, Pp 1-12 (2022)
مصطلحات موضوعية: De novo drug design, Reinforcement learning, Conditional Variational AutoEencoder, Sorafenib, Raf kinases, Information technology, T58.5-58.64, Chemistry, QD1-999
وصف الملف: electronic resource
العلاقة: https://doaj.org/toc/1758-2946Test
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7دورية أكاديمية
المؤلفون: Van, Que N, López, Cesar A, Tonelli, Marco, Taylor, Troy, Niu, Ben, Stanley, Christopher B, Bhowmik, Debsindhu, Tran, Timothy H, Frank, Peter H, Messing, Simon, Alexander, Patrick, Scott, Daniel, Ye, Xiaoying, Drew, Matt, Chertov, Oleg, Lösche, Mathias, Ramanathan, Arvind, Gross, Michael L, Hengartner, Nicolas W, Westler, William M, Markley, John L, Simanshu, Dhirendra K, Nissley, Dwight V, Gillette, William K, Esposito, Dominic, McCormick, Frank, Gnanakaran, S, Heinrich, Frank, Stephen, Andrew G
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 117(39)
مصطلحات موضوعية: Biochemistry and Cell Biology, Chemical Sciences, Biological Sciences, Cancer, 2.1 Biological and endogenous factors, Aetiology, Cell Membrane, Molecular Dynamics Simulation, Proto-Oncogene Proteins p21(ras), raf Kinases, KRAS, RAF RBD, membrane, neutron reflectometry, nuclear magnetic resonance
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/7pp4r86xTest
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8دورية أكاديمية
المؤلفون: del Río, Isabel Boned, Young, Lucy C, Sari, Sibel, Jones, Greg G, Ringham-Terry, Benjamin, Hartig, Nicole, Rejnowicz, Ewa, Lei, Winnie, Bhamra, Amandeep, Surinova, Silvia, Rodriguez-Viciana, Pablo
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(27)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cancer, 1.1 Normal biological development and functioning, Underpinning research, CRISPR-Associated Protein 9, CRISPR-Cas Systems, Cell Line, Tumor, Gene Editing, Gene Knockout Techniques, Humans, Intracellular Signaling Peptides and Proteins, MAP Kinase Signaling System, Phosphorylation, Protein Multimerization, raf Kinases, ras Proteins, SHOC2, RAF, MRAS, RAS, ERK
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/8r21q8v7Test
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9دورية أكاديمية
المؤلفون: Jones, Greg G, del Río, Isabel Boned, Sari, Sibel, Sekerim, Aysen, Young, Lucy C, Hartig, Nicole, Areso Zubiaur, Itziar, El-Bahrawy, Mona A, Hynds, Rob E, Lei, Winnie, Molina-Arcas, Miriam, Downward, Julian, Rodriguez-Viciana, Pablo
المصدر: Nature Communications. 10(1)
مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Biological Sciences, Cancer, Lung, Lung Cancer, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Animals, Apoptosis, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Drug Resistance, Neoplasm, Female, HEK293 Cells, Humans, Intracellular Signaling Peptides and Proteins, Lung Neoplasms, MAP Kinase Signaling System, Male, Mice, Knockout, Mice, Nude, Mutation, Neoplasm Transplantation, Protein Kinase Inhibitors, Protein Multimerization, raf Kinases, ras Proteins
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/8kc5p1gjTest
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10دورية أكاديمية
المؤلفون: Young, Lucy C, Hartig, Nicole, Boned Del Río, Isabel, Sari, Sibel, Ringham-Terry, Benjamin, Wainwright, Joshua R, Jones, Greg G, McCormick, Frank, Rodriguez-Viciana, Pablo
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 115(45)
مصطلحات موضوعية: Cell Line, Humans, Noonan Syndrome, ras Proteins, raf Kinases, Intracellular Signaling Peptides and Proteins, Carrier Proteins, Sequence Alignment, MAP Kinase Signaling System, Phosphorylation, Mutation, Models, Molecular, Protein Phosphatase 1, HEK293 Cells, MRAS, Noonan syndrome, PP1, RAS, SHOC2, 1.1 Normal biological development and functioning, Underpinning research, Generic health relevance
وصف الملف: application/pdf
الوصول الحر: https://escholarship.org/uc/item/9ct3g7stTest