دورية أكاديمية
Clinical Characteristics and Outcomes of 905 COVID-19 Patients Admitted to Imam Khomeini Hospital Complex in the Capital City of Tehran, Iran
| العنوان: | Clinical Characteristics and Outcomes of 905 COVID-19 Patients Admitted to Imam Khomeini Hospital Complex in the Capital City of Tehran, Iran |
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| المؤلفون: | Allameh, Seyed Farshad, Nemati, Saeed, Ghalehtaki, Reza, Mohammadnejad, Esmaeil, Aghili, Seyed Mojtaba, Khajavirad, Nasim, Beigmohammadi, Mohammad-Taghi, Salehi, Mohammadreza, Mirfazaelian, Hadi, Edalatifard, Maryam, Kazemizadeh, Hossein, Dehghan Manshadi, Seyed Ali, Hasannezhad, Maliheh, Amoozadeh, Laya, Radnia, Masoud, Khatami, Seyedeh Rana, Nahvijou, Azin, Seyyedsalehi, Monireh Sadat, Rashidian, Laleh, Ayoobi Yazdi, Niloofar, Nasiri Toosi, Mohsen, Sadeghniiat-Haghighi, Khosro, Jafarian, Ali, Yunesian, Masud, Zendehdel, Kazem |
| المصدر: | Archives of Iranian Medicine ; volume 23, issue 11, page 766-775 ; ISSN 1029-2977 1735-3947 |
| بيانات النشر: | Maad Rayan Publishing Company |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | General Medicine |
| الوصف: | Background: We studied the clinical characteristics and outcomes of 905 hospitalized coronavirus disease 2019 (COVID-19) patients admitted to Imam Khomeini Hospital Complex (IKHC), Tehran, Iran. Methods: COVID-19 patients were recruited based on clinical symptoms and patterns of computed tomography (CT) imaging between February 20 and March 19. All patients were tested for the presence of COVID-19 RNA. The Poisson regression model estimated the incidence rate ratio (IRR) for different parameters. Results: The average age (± standard deviation) was 56.9 (±15.7) years and 61.77% were male. The most common symptoms were fever (93.59%), dry cough (79.78%), and dyspnea (75.69%). Only 43.76% of patients were positive for the RT-PCR COVID-19 test. Prevalence of lymphopenia was 42.9% and more than 90% had elevated lactate dehydrogenase (LDH) or C-reactive protein (CRP). About 11% were severe cases, and 13.7% died in the hospital. The median length of stay (LOS) was 3 days. We found higher risks of mortality in patients who were older than 70 years (IRR = 11.77, 95% CI 3.63–38.18), underwent mechanical ventilation (IRR = 7.36, 95% CI 5.06–10.7), were admitted to the intensive care unit (ICU) (IRR = 5.47, 95% CI 4.00–8.38), tested positive on the COVID-19 test (IRR = 2.80, 95% CI 1.64–3.55), and reported a history of comorbidity (IRR = 1.76, 95% CI 1.07–2.89) compared to their corresponding reference groups. Hydroxychloroquine therapy was not associated with mortality in our study. Conclusion: Older age, experiencing a severe form of the disease, and having a comorbidity were the most important prognostic factors for COVID-19 infection. Larger studies are needed to perform further subgroup analyses and verify high-risk groups. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.34172/aim.2020.102 |
| الإتاحة: | https://doi.org/10.34172/aim.2020.102Test http://www.aimjournal.ir/PDF/aim-23-766.pdfTest |
| رقم الانضمام: | edsbas.D3508C74 |
| قاعدة البيانات: | BASE |
| DOI: | 10.34172/aim.2020.102 |
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