-
1
المؤلفون: Sarina Kajani, Sean Curley, Marcella E. O'Reilly, Xiaofei Yin, Eugene T. Dillon, Weili Guo, Kanishka N. Nilaweera, Lorraine Brennan, Helen M. Roche, Fiona C. McGillicuddy
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 56, Iss, Pp 101425-(2022)مصطلحات موضوعية: HFD, High-fat diet, RXR, retinoid-X-receptor, Sodium Salicylate, ABCB11, ATP binding cassette (ABC) transporter subfamily B member 11, PPAR, peroxisome proliferator-activator receptor, Mice, HDL, High-density lipoprotein, Animals, Liver proteomics, Obesity, Molecular Biology, Internal medicine, RCT, Reverse Cholesterol Transport, IPA, Ingenuity Pathway Analysis, LXR, liver-X-receptor, ABCA1, ATP binding cassette (ABC) transporter subfamily A, member 1, Hepatosteatosis, Cell Biology, RC31-1245, Metabolic inflammation, cAMP, cyclic adenosine monophosphate, Mice, Inbred C57BL, Reverse cholesterol transport, Cholesterol, ABCG5/8, ATP binding cassette (ABC) transporter subfamily G, member 5/8, Liver, lipids (amino acids, peptides, and proteins), Original Article, HDL proteomics, Metabolic Networks and Pathways
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd64a6ca0d0d390204b0035129b8ef9Test
http://europepmc.org/articles/PMC8762459Test -
2
المؤلفون: Harshit Shah, Lizhi Pang, Steven Y. Qian, Yi Xu
المصدر: Translational Oncology, Vol 14, Iss 11, Pp 101207-(2021)
Translational Oncologyمصطلحات موضوعية: Cancer Research, EDA, eicosadienoic acid, MDSCs, myeloid-derived suppressor cells, 5-LOX, 5-lipoxygenase, Prostaglandin E2, AA, arachidonic acid, Review, 8-HOA, 8-hydroxyoctanoic acid, POBN, α-(4-Pyridyl 1-oxide)-N-tert-butylnitrone, chemistry.chemical_compound, ETA, eicosatetraenoic acid, SNP, single-nucleotide acid polymorphism, RNA interference, ELOVL5, elongation of very long-chain fatty acid protein 5, HDAC, histone deacetylases, Medicine, Receptor, RC254-282, chemistry.chemical_classification, TCGA, the cancer genome atlas, TME, tumor microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Delta-5 desaturase, PGs, prostaglandins, LTs, leukotrienes, MMP, matrix metalloproteinase, Tumor inflammation, D5D, delta-5-desaturase, RNAi, RNA interference, EpCAM, epithelial cell adhesion molecule, Oncology, COX-2, cyclooxygenase-2, GPX4, glutathione peroxidase 4, TAZ, transcriptional coactivator with PDZ-binding motif, Arachidonic acid, EMT, epithelial-mesenchymal transition, Polyunsaturated fatty acid metabolism, Programmed cell death, RXR, retinoid X receptor, SREBP-1c, sterol regulatory element-binding protein 1c, 8-hydroxyoctanoic acid, ER, endoplasmic reticulum, DNMT3B, DNA methyltransferase 3B, ROS, reactive oxygen species, PGE2, prostaglandin E2, DGLA, dihomo-γ-linolenic acid, 5-FU, fluorouracil, 3WJ, 3-way junction, PPARα, peroxisome proliferator-activated receptor α, Fatty acid metabolism, business.industry, PUFAs, polyunsaturated fatty acids, Cancer, EPA, eicosapentaenoic acid, medicine.disease, Bax, Bcl-2-associated X protein, Enzyme, chemistry, Cancer cell, Cancer research, HAT, histone acetyltransferase, LXR, liver X receptor, business, YAP1, yes-associated protein-1
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c81cba5e09eeffe1477f02b7b3cd5fa8Test
http://www.sciencedirect.com/science/article/pii/S1936523321001996Test -
3
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: HBsAg, NTCP, sodium taurocholate cotransporting polypeptide, vitamin D, medicine.disease_cause, Biochemistry, Calcitriol receptor, 6-FAM, 6-carboxyfluorescein, polycyclic compounds, nuclear receptor, Hepatitis B e Antigens, Promoter Regions, Genetic, Chemistry, pcRNA, precore RNA, virus diseases, NR, nuclear receptor, Hep G2 Cells, Hepatitis B, IVT, in vitro translated, VDRE, ChIP, chromatin immunoprecipitation, HBx, HBsAg, hepatitis B surface antigen, VDR, vitamin D receptor, lipids (amino acids, peptides, and proteins), vitamin D response element, medicine.drug, Research Article, Hepatitis B virus, Calcitriol, RXR, retinoid X receptor, Retinoid X receptor, HBeAg, hepatitis B “e” antigen, antiviral agent, Vitamin D Response Element, medicine, cell signaling, vitamin D receptor, Humans, viral transcription, Molecular Biology, HBV core promoter, DR, direct repeat, pgRNA, pregenomic RNA, Cell Biology, Molecular biology, digestive system diseases, HBV, hepatitis B virus, Retinoid X Receptors, VDRE, vitamin D response element, Receptors, Calcitriol, CHB, chronic HBV, qPCR, quantitative PCR, gene regulation, HCC, hepatocellular carcinoma
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d15edd2674c6687847a92d9ea83c572Test
http://europepmc.org/articles/PMC8517215Test -
4
المؤلفون: Natarajan Balasubramaniyan, Frederick J. Suchy, David J. Orlicky, Ronald J. Sokol, Michael W. Devereaux
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Male, ABCC2, ATP-binding cassette sub-family C member 2, RXR, retinoid X receptor, Repressor, Retinoid X receptor, Chenodeoxycholic Acid, ATP-dependent efflux transporter, Biochemistry, FXR, arnesoid X receptor, miR, microRNA, chemistry.chemical_compound, Mice, Cholestasis, MRP2, multidrug resistance-associated protein 2, medicine, Animals, Nuclear Receptor Co-Repressor 1, canalicular, SMRT, silencing mediator of retinoic acid and thyroid hormone receptor, ABCB11, Molecular Biology, Nuclear receptor co-repressor 1, ATP Binding Cassette Transporter, Subfamily B, Member 11, BSEP, bile salt export pump, Mice, Knockout, bile acids, microRNA, Multidrug resistance-associated protein 2, NCOR1, nuclear receptor corepressor 1, Obeticholic acid, Cell Biology, ABCB11, ATP-binding cassette sub-family B member 11, medicine.disease, Molecular biology, Disease Models, Animal, MicroRNAs, Nr1h4, nuclear receptor subfamily 1, group H, member 4, chemistry, Gene Expression Regulation, OCA, obeticholic acid, Farnesoid X receptor, Research Article, biliary
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1a013e773a28d1858652b76631c178cTest
https://pubmed.ncbi.nlm.nih.gov/34774795Test -
5
المؤلفون: Carmen Berasain, Matías A. Avila
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 291-293 (2021)مصطلحات موضوعية: Vitamin, Leptin, Male, HFD, high-fat diet, 17-Hydroxysteroid Dehydrogenases, RXR, retinoid X receptor, RBP4, retinol binding protein 4, Mice, Transgenic, Fatty Liver Disease, Bioinformatics, Diet, High-Fat, chemistry.chemical_compound, Mice, Non-alcoholic Fatty Liver Disease, qHSC, quiescent hepatic stellate cell, Nonalcoholic fatty liver disease, Hepatic Stellate Cells, Medicine, Animals, Humans, lcsh:RC799-869, Vitamin A, Original Research, HFC, high-fat, high-cholesterol, Hepatology, business.industry, Gastroenterology, medicine.disease, Lipid Metabolism, HSC, hepatic stellate cell, mRNA, messenger RNA, Position (obstetrics), Disease Models, Animal, Editorial, chemistry, Liver, RAR, retinoic acid receptor, Phospholipases A2, Calcium-Independent, Autofluorescence, Disease Progression, Hepatocytes, lcsh:Diseases of the digestive system. Gastroenterology, Female, NAFLD, nonalcoholic fatty liver disease, business, Retinol-Binding Proteins, Plasma
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5439dee46af356b9b78da104751c70Test
http://europepmc.org/articles/PMC7768560Test -
6
المؤلفون: Kenji Kamimoto, Samantha A. Morris, Brad W. Warner, Cathleen M. Courtney, Wenjun Kong, William H. Goo, Sarah E. Waye, Kristen M. Seiler, Adam Bajinting, Jun Guo, Emily J. Onufer
المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 8, Iss 3, Pp 407-426 (2019)مصطلحات موضوعية: 0301 basic medicine, Male, SBR, small bowel resection, PBST, phosphate-buffered saline + TWEEN 20, Single-Cell RNA Sequencing, Mice, 0302 clinical medicine, Single-cell analysis, RARE, retinoic acid response element, RNA, Small Nuclear, Gene expression, Intestine, Small, RA, retinoic acid, Gene Regulatory Networks, Cyclic AMP Response Element-Binding Protein, ADA, adenosine deaminase, Original Research, scRNA-seq, single-cell RNA sequencing, 0303 health sciences, Short Gut Syndrome, Gastroenterology, SGS, short gut syndrome, Cellular Reprogramming, PPRE, peroxisome proliferator-activated receptor response element, mRNA, messenger RNA, Cell biology, Up-Regulation, medicine.anatomical_structure, 030220 oncology & carcinogenesis, AU, arbitrary units, Enterocyte, qPCR, quantitative polymerase chain reaction, 030211 gastroenterology & hepatology, Stem cell, Single-Cell Analysis, Reprogramming, Creb3l3, Retinoid Metabolism, TOM, Topological Overlap Matrix, RNA-FISH, RNA fluorescence in situ hybridization, RXR, retinoid X receptor, PBS, phosphate-buffered saline, Biology, 03 medical and health sciences, cDNA, complementary DNA, PN, parenteral nutrition, SI, small intestine, Downregulation and upregulation, medicine, UMAP, Uniform Manifold Approximation and Projection, Animals, lcsh:RC799-869, Transcription factor, UMI, unique molecular identifier, 030304 developmental biology, Hepatology, PPARα, peroxisome proliferator-activated receptor alpha, Sequence Analysis, RNA, Gene Expression Profiling, DGE, digital gene expression, TA, transit amplifying, Lipid Metabolism, Epithelium, Small intestine, Oxidative Stress, 030104 developmental biology, Enterocytes, RAR, retinoic acid receptor, QP, quadratic programming, lcsh:Diseases of the digestive system. Gastroenterology, Unsupervised Machine Learning
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee63d6c1e370ac6859fe49b3aee2f738Test
http://europepmc.org/articles/PMC6718927Test -
7
المؤلفون: Yitao Wang, Jingxin Liu, Ligen Lin
المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 9, Iss 2, Pp 220-236 (2019)مصطلحات موضوعية: SNS, sympathetic nervous system, C/EBPα, CCAAT/enhancer binding protein α, PDEs, phosphodiesterases, OXPHOS, oxidative phosphorylation, FGF21, fibroblast growth factor 21, Review, Type 2 diabetes, Brown adipose tissue, Bioinformatics, Energy homeostasis, CRABP-II, cellular RA binding protein type II, 0302 clinical medicine, HFD, high fat diet, Weight loss, RA, retinoic acid, RARE, RA response element, BMP8b, bone morphogenetic protein 8b, General Pharmacology, Toxicology and Pharmaceutics, media_common, 0303 health sciences, SIRT1, silent mating type information regulation 2 homolog 1, PXR, pregnane X receptor, TFAM, mitochondrial transcription factor A, WAT, white adipose tissue, Thermogenesis, PPREs, peroxisome proliferator response elements, FAS, fatty acid synthase, Thermogenin, cAMP, cyclic adenosine monophosphate, PTP1B, protein-tyrosine phosphatase 1B, medicine.anatomical_structure, BA, bile acids, 030220 oncology & carcinogenesis, VDR, vitamin D receptor, CRE, cAMP response element, medicine.symptom, PET-CT, positron emission tomography combined with computed tomography, PRDM16, PR domain containing 16, ATP, adenosine triphosphate, RXR, retinoid X receptor, media_common.quotation_subject, VDRE, VDR response elements, AKT, protein kinase B, 03 medical and health sciences, TMEM26, transmembrane protein 26, CLA, cis-12 conjugated linoleic acid, ERE, estrogen response element, UCP1, uncoupling protein 1, medicine, PGC-1α, peroxisome proliferator-activated receptor γ coactivator 1-α, Obesity, β3-AR, β3-adrenergic receptor, 030304 developmental biology, ERs, estrogen receptors, LXR, liver X receptors, PPARs, peroxisome proliferator-activated receptors, business.industry, lcsh:RM1-950, Cidea, cell death-inducing DNA fragmentation factor α-like effector A, Uncoupling protein 1, Appetite, RMR, resting metabolic rate, medicine.disease, Dio2, iodothyronine deiodinase type 2, Beige cells, ALDH9, aldehyde dehydrogenase 9, BAT, brown adipose tissue, AMPK, AMP-activated protein kinase, lcsh:Therapeutics. Pharmacology, RAR, RA receptor, cGMP, cyclic guanosine monophosphate, PKA, protein kinase A, GPCRs, G protein-coupled receptors, TRPs, transient receptor potential cation channels, business, MAPK, mitogen-activated protein kinase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee24ee4e685885a371ae80f1d618f98Test
https://doi.org/10.1016/j.apsb.2018.09.007Test -
8
المؤلفون: Jamie M. Aye, Raoud Marayati, Laura L. Stafman, Elizabeth A. Beierle, Adele P. Williams, Laura V. Bownes, Colin H. Quinn, Venkatram R. Atigadda, Karina J. Yoon, Jerry E. Stewart
المصدر: Translational Oncology, Vol 14, Iss 1, Pp 100893-(2021)
Translational Oncologyمصطلحات موضوعية: 0301 basic medicine, Agonist, Cancer Research, Original article, IRB, Institutional Review Board, Neurite, Oct4, Octamer-binding transcription factor 4, medicine.drug_class, GAP43, Growth Associated Protein 43, APC, Allophycocyanin, Cell, Retinoic acid, PDX, Patient-derived xenografts, Motility, qPCR, Real-time PCR, CADD, Combined Annotation Dependent Depletion, IACUC, Institutional Animal Care and Use Committee, lcsh:RC254-282, 03 medical and health sciences, chemistry.chemical_compound, Sox2, Sex determining region Y-box 2, RARE, Retinoic acid response elements, 0302 clinical medicine, Maintenance therapy, ELDA, Extreme limiting dilution assay, Neuroblastoma, RA, Retinoic acid, medicine, RPMI, Roswell Park Memorial Institute, SCLCCs, Stem cell-like cancer cells, RAR, Retinoic acid receptor, HOXC9, Homeobox C9 protein, DMSO, Dimethyl sulfoxide, RXR, Retinoid X receptor, IgG1, Imunoglobulin G1, medicine.disease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, PBS, Phosphate-buffered saline, 030104 developmental biology, medicine.anatomical_structure, SEM, Standard error of the mean, Oncology, chemistry, 030220 oncology & carcinogenesis, Cancer cell, UAB30, 9-cis-UAB30, Cancer research, ANOVA, Analysis of variance, NSE, Neuron Specific Enolase
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e0ffc188566ee79402dd188357b638Test
http://www.sciencedirect.com/science/article/pii/S1936523320303855Test -
9
المؤلفون: Martina Poturnajova, Zuzana Kozovska, Miroslava Matuskova
المصدر: Cellular Signalling
مصطلحات موضوعية: SMAD4, Mothers against decapentaplegic homolog 4, TLX-1, T-cell leukemia homeobox protein 1, Bcl-2, B-cell lymphoma 2, apoptosis regulator, PPARβ/δ, Peroxisome-proliferator-activated receptor β/δ, Retinoic acid, Aldehyde dehydrogenase, NSPc1, Polycomb 1 of the nervous system, Transcriptional control, TGF- β, Transforming growth factor beta, DHT, Dihydrotestosterone, BRD4, bromodomain-containing protein 4, chemistry.chemical_compound, SRC, proto-oncogene tyrosine-protein kinase, MDR, multidrug resistance, RARRES1, Retinoic acid receptor responder 1, Neoplasms, EZH2, Enhancer of zeste homolog 2, HPCs, hematopoietic progenitors, MEK, Mitogen-activated protein kinase, Transcriptional regulation, Protein Isoforms, RAR, Retinoic acid receptor, cMET (HGFR), Hepatocyte growth factor receptor, TNBC, triple negative breast cancer, biology, Chemistry, HOX, Homeobox protein, ERK, Extracellular signal-regulated kinase, NFκB, Nuclear factor kappa-light-chain-enhancer of activated B cells, Stem cells marker, NANOG, homeobox protein, transcriptional factor, C/EBPβ, CCAAT/enhancer-binding protein β, HNSCC, Head and neck squamous Cancer, Aldehyde Oxidoreductases, Graphical Review, PCAF, acetyltransferase P300/CBP-associated factor, ER, Estrogen receptor, Cell biology, MMP, matrix metalloproteinase, Crosstalk (biology), Molecular regulation, S1P, Sphingosine-1-phosphate, IL-6, Interleukin 6, NRF2, Nuclear respiratory factor 1, SOX2, SRY (sex determining region Y)-box 2, Stem cell, EMT, epithelial-mesenchymal transition, SIRT2, Sirtuin 2, CD24, signal transducer 24, sialoglycoprotein, Gene isoform, atRA, all trans retinoic acid, GADD153, Growth arrest and DNA damage 153, SNAI2, (Slug) zinc finger protein 2, MUC1-C, Mucin 1 glycoprotein, subunit C, Tretinoin, CDK2, Cyclin- dependent kinase 2, CHOP, C/EBP homologous protein, PI3K, Phosphatidylinositol 3-kinase, Aldehyde Dehydrogenase 1 Family, CD44, homing cell adhesion molecule, BAX, Bcl-2-like protein 4, apoptosis regulator, TCF4 (TCF7L2), Transcription factor 7-like 2, HSP27, heat shock protein 27, ROS, reactive oxygen species, RA, Retinoic acid, Humans, BET, bromodomain and extraterminal protein family, RARE, RA responsive element, SNAI1, (Snail) zinc finger protein 1, DANCR (KIAA0114), Differentiation antagonizing non-protein coding RNA, PTEN, Phosphatase and tensin homolog, ALDH1A13, aldehyde dehydrogenase 1 isoforms A1, A3, Mechanism (biology), Retinal Dehydrogenase, mTOR, Mammalian target of rapamycin, RXR, Retinoid X receptor, Cell Biology, HGF, Hepatocyte growth factor, CSC, cancer stem cell, NQO1, NAD(P)H dehydrogenase [quinone] 1, STAT3, Signal transducer and activator of transcription 3, ALDH1A1, CD31, Platelet endothelial cell adhesion molecule 1, RD16, retinol dehydrogenase 16, DDIT3, DNA damage inducible transcript 3, NRAD1 (LINC00284), Non-coding RNA in the aldehyde dehydrogenase 1A pathway, biology.protein, AR, androgen receptor
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1457905c555ffd74710c72192f7cc6ceTest
https://doi.org/10.1016/j.cellsig.2021.110120Test -
10
المؤلفون: Whitney Kilu, Dieter Steinhilber, Daniel Merk, Jan Heering, Ewgenij Proschak
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: 0301 basic medicine, PPARγ, Peroxisome proliferator-activated receptor, PPAR, peroxisome proliferator-activated receptor, Ligands, Biochemistry, Benzoates, drug target, Nuclear Receptor Coactivator 1, LBD, ligand-binding domain, heterodimer, TETRAC, non-classical thyroid hormone 3,3',5,5'-tetraiodothyroacetic acid, homogeneous time-resolved FRET (HTRF), Tb-SA, terbium cryptate conjugated to streptavidin, chemistry.chemical_classification, allostery, Protein Stability, cofactor recruitment, NR, nuclear receptor, Ligand (biochemistry), CREB-Binding Protein, Cell biology, Research Article, Transcriptional Activation, homodimer, RXR, retinoid X receptor, Allosteric regulation, Retinoid X receptor, Rosiglitazone, 03 medical and health sciences, Retinoids, CBP-1, CREB-binding protein coactivator motif 1, FXR, farnesoid X receptor, Protein Domains, Coactivator, RXRα, Humans, HTRF, homogeneous time-resolved FRET, Molecular Biology, Retinoid X Receptor alpha, 030102 biochemistry & molecular biology, SRC1-2, steroid receptor coactivator 1 motif 2, Reproducibility of Results, sGFP, super folder green fluorescent protein, Cell Biology, PPAR gamma, Retinoic acid receptor, 030104 developmental biology, HEK293 Cells, chemistry, Nuclear receptor, DBD, DNA-binding domain, Mutation, Farnesoid X receptor, Protein Multimerization, AF-2, activation function 2
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a651259b1d286bcaadc32e55691b956Test
https://pubmed.ncbi.nlm.nih.gov/34081964Test