المؤلفون: Kaneez Fatima, Abha Meena, Suaib Luqman, Nusrat Masood, Zahoor Ahmad Wani

المصدر: Journal of Advanced Research

مصطلحات موضوعية: TRIG, Triglyceraldehyde, Skin Neoplasms, Cell, DOXO, Doxorubicin, Hyaluronidase, Pharmacology, NaOH, Sodium hydroxide, Polymerization, MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, Mice, 0302 clinical medicine, BIL, Bilirubin total & direct, Neomenthol, PEP A, pepstatin A, Cancer biomarker, MEF, Mean erythrocyte fragility, HYAL, Hyaluronidase, PBS, Phosphate buffer saline, CM-H2DCFDA, Chloromethyl derivative of dichloro fluorescin diacetate, HA, Hyaluronic acid, Epidermoid carcinoma, Human epidermoid carcinoma, 030220 oncology & carcinogenesis, RBC, Red blood cell, DMEM, Dulbecco’s minimal essential media, SRB, Sulphorhodamine B, BUN, Blood urea nitrogen, FACS, Fluorescence-Activated Cell Sorting, AKLP, Alkaline phosphatase, Hyaluronoglucosaminidase, NADPH, Nicotinamide adenine dinucleotide phosphate hydrogen, TMPD, N,N,N′,N′-tetramethyl-p-phenylenediamine, Article, 03 medical and health sciences, In vivo, Ehrlich Ascites Carcinoma, BE, Binding energy, Humans, CATD, Cathepsin D, LDH, Lactate dehydrogenase, COX-2, Cyclooxygenase 2, FOX, Ferrous oxidation-xylenol orange, DMSO, Dimethyl sulfoxide, mTOR, Mammalian target of rapamycin, In vitro, Ab/Am, Antibiotic/antimycotic, NRU, Neutral red uptake, EC50, Half maximal effective concentration, 030104 developmental biology, IC50, Half maximal inhibitory concentration, EAC, Ehlrich Ascites Carcinoma, RPMI, Roswell park memorial institute, ROS, Reactive oxygen species, 0301 basic medicine, HDL, High density lipoprotein, TNBS, Trinitrobenzenesulphonic acid, PI3K, Phosphotidyl inositol-3 kinase, URIC, Uric acid, DNA, Deoxyribonucleic acid, GAPDH, Glyceraldehyde 3-phosphate dehydrogenase, HEPES, N-2-hydroxyethylpiperazine-N′-2-ethanesulfonic acid, Tubulin, OECD, Organization for Economic Co-operation and Development, SGPT, Alanine aminotransferase, LOX-5, Lipoxygenase-5, DFMO, α-difluoro methyl ornithine, Multidisciplinary, WBC, White blood cell, Chemistry, ELISA, enzyme-linked immunosorbent assay, PKB/Akt, Protein kinase B, AA, Arachidonic acid, RNase A, Ribonuclease A, TPR, Total protein, Molecular Docking Simulation, medicine.anatomical_structure, TCA, Tricarboxylic acid, CHOL, Cholesterol, Ki, Inhibitory constant, medicine.drug, ODC, Ornithine decarboxylase, DHFR, Dihydrofolatereductase, BSA, Bovine serum albumin, PDB, Protein Data Bank, medicine, Animals, MMP, Mitochondrial membrane potential, DCFDA, 2′,7′ dichloro fluorescin diacetate, RNA, Ribonucleic acid, RIPA, Radio immune precipitation assay buffer, EDTA, Ethylene diamine tetra acetic acid, IC50, TPA, 12-O-Tetradecanoylphorbol-13-acetate, ComputingMethodologies_COMPUTERGRAPHICS, TRPM8, Transient receptor potential member 8, Cell Proliferation, HDAC, Histone deacetylase, MTX, Methotrexate, OF, Osmotic fragility, PI, Propidium iodide, FDA, Food and Drug Administration, HEK293 Cells, PDT, Podophyllotoxin, Cell culture, NAC, N-acetyl cysteine, SGOT, Aspartate aminotransferase, CRTN, Creatinine, FBS, Fetal bovine serum, PCR, Polymerase chain reaction, Rh123, Rhodamine 123, Ex vivo, IDT, Integrated DNA Technologies

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7618e7dc6e2d535e1930d5f8c2bf7d7eTest
https://doi.org/10.1016/j.jare.2021.06.003Test

المؤلفون: Alaa A. A. Aljabali, Nitin Charbe, Poonam Negi, Nikhil D. Amnerkar, Gaurav Gupta, B. Ramesh, Meenu Metha, Hamid A. Bakshi, Dinesh Kumar Chellappan, Saurabh C. Khadse, Garima Shrivastava, Saurabh Satija, Kamal Dua, Flavia C. Zacconi, Murtaza M. Tambuwala, Rajendran Satheeshkumar

المصدر: Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: Small interfering RNA, PE-PCL-b-PNVCL, pentaerythritol polycaprolactone-block-poly(N-vinylcaprolactam), DSPE-MPEG, 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (ammonium salt), Review, 0302 clinical medicine, micro RNA, MPEG, poly(ethylene glycol)-block-poly(l-lysine), PEI, General Pharmacology, Toxicology and Pharmaceutics, Polymer, Micelles, Cancer, DOPC, dioleylphosphatidyl choline, DSPE-PEG-Mal: 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] (mmmonium salt), EPR, 0303 health sciences, poly(acrylhydrazine)-block-poly(3-dimethylaminopropyl methacrylamide)-block-poly(acrylhydrazine), PCL, S–Au, thio‒gold, AQP-5, aquaporin-5, CMC, critical micelles concentration, DOTAP, N-[1-(2,3-dioleoyloxy)propyl]-N,N,N-trimethylammonium methyl-sulfate, Cancer treatment, APOB, apolipoprotein B, Nanomedicine, RNAi, RNA interference, poly(ethylene glycol)-block-poly(2-dimethylaminoethyl methacrylate)-block poly(pyrenylmethyl methacrylate), PEG-b-PLL, 030220 oncology & carcinogenesis, B-PEI, branched polyethlenimine, Atufect01, β-l-arginyl-2,3-l-diaminopropionicacid-N-palmityl-N-oleyl-amide trihydrochloride, CHEMS, cholesteryl hemisuccinate, DSGLA, N,N-dis-tearyl-N-methyl-N-2[N′-(N2-guanidino-l-lysinyl)] aminoethylammonium chloride, SEM, scanning electron microscope, messenger RNA, MTX, polycaprolactone-polyethylenimine, PDMA, BMA, butyl methacrylate, 03 medical and health sciences, TCC - Transitional cell carcinoma, RNAse III, ribonuclease III enzyme, methotrexate, NIR, ZEBOV, Zaire ebola virus, DSPC, 1,2-distearoyl-sn-glycero-3-phosphocholine, lysine ethyl ester diisocyanate, LPD/LPH, poly(N-isopropyl acrylamide), pentaerythritol polycaprolactone-block-poly(N-isopropylacrylamide), medicine.disease, CFTR, cystic fibrosis transmembrane conductance regulator gene, UV, ultraviolet, Cancer cell, Liposomes, PPES-b-PEO-b-PPES, poly(4-(phenylethynyl)styrene)-block-PEO-block-poly(4-(phenylethynyl)styrene), RES, reticuloendothelial system, hypoxia-inducible factor-1α, KSP, DMAEMA, 2-dimethylaminoethyl methacrylate, N-acetylgalactosamine, HIF-1α, DNA, deoxyribonucleic acid, USPIO, ultra-small superparamagnetic iron oxide nanoparticles, enhanced permeability and retention, Galnac, RISC, RNA-induced silencing complex, nanoparticle, NRP-1, near-infrared, NP, methoxypoly(ethylene glycol), MPEG-PCL, 1,3-propanediol, PEG-b-PDMAEMA-b-Ppy, neuropilin-1, PAA, PLGA, poly lactic-co-glycolic acid, methoxy polyethylene glycol-polycaprolactone, mRNA, poly(N,N-dimethylacrylamide), PDO, VEGF, vascular endothelial growth factor, PLL, poly-l-lysine, lipid-protamine-DNA/hyaluronic acid, MDR, DSPE, 1,2-distearoyl-sn-glycero-3-phosphorylethanolamine, Drug delivery, RGD, Arg-Gly-Asp peptide, SNALP, stable nucleic acid-lipid particles, poly(Ε-caprolactone)-polyethyleneglycol-poly(l-histidine), PCL-PEI, DOTMA, N-[1-(2,3-dioleyloxy)propy]-N,N,N-trimethylammoniumchloride, kinesin spindle protein, LDI, Small interfering RNA (siRNA), 2-propylacrylicacid, PAH-b-PDMAPMA-b-PAH, AZEMA, azidoethyl methacrylate, poly(ethylene oxide)-block-poly(2-(diethylamino)ethyl methacrylate)-stat-poly(methoxyethyl methacrylate), PEO-b-PCL, AuNPs, gold nanoparticles, TCC, transitional cell carcinoma, Tf, transferrin, medicine, multiple drug resistance, MiRNA, TEM, transmission electron microscopy, 030304 developmental biology, PLK-1, polo-like kinase 1, poly(ethylene oxide)-block-poly(Ε-caprolactone), PE-PCL-b-PNIPAM, poly(Ε-caprolactone), PCL-PEG, CHOL, cholesterol, PLA, poly-l-arginine, DC-Chol, 3β-[N-(N′,N′-dimethylaminoethane)carbamoyl]cholesterol, Trka, tropomyosin receptor kinase A, polyethylenimine, PEO-b-P(DEA-Stat-MEMA, DOX, doxorubicin, polycaprolactone-polyethyleneglycol, PCL-PEG-PHIS, DOPE, dioleylphosphatidyl ethanolamine, PTX, paclitaxel, PiRNA, piwi-interacting RNA, Cancer research, RNA, ribonucleic acid, SiRNA, short interfering rNA, Nanocarriers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2071f422f1c1f8a688b18780d3afbc9cTest
https://pubmed.ncbi.nlm.nih.gov/33304780Test

المؤلفون: Satheeswaran Balasubramanian, Ekambaram Perumal, Vignesh Jeyamanickavel Mathan, Kanmani Gunasekaran, Saranyadevi Sasidharan

المصدر: Toxicology Reports
Toxicology Reports, Vol 7, Iss, Pp 583-595 (2020)

مصطلحات موضوعية: microRNAs: Potential biomarkers of toxicity, Nrf2, Nuclear factor erythroid 2-related factor 2, Aβ, Amyloid Beta, Toxicology, 01 natural sciences, Non-coding RNAs, AHR, Aryl Hydrocarbon Receptor, 0302 clinical medicine, CDK6, Cyclin-dependent kinase 6, NMDAR, N-methyl-d-aspartate receptor, TP53, Tumor protein 53, BaP, Benzo[a]pyrene, NPs, Nanoparticles, Regulation of gene expression, Hpf, Hours post fertilization, qRT-PCR, quantitative Real Time-Polymerase Chain Reaction, CDKN1b, Cyclin-dependent kinase Inhibitor 1B, Wnt, Wingless-related integration site, HSPA1A, Heat shock 70 kDa protein 1, IL1R1, Interleukin 1 receptor, type 1, ER, Endoplasmic Reticulum, PDCD4, Programmed cell death protein 4, MC-RR, Microcystin-Arginine Arginine, RNAi, RNA interference, DGCR8, DiGeorge syndrome chromosomal [or critical] region 8, Epigenetics, GTP, Guanosine triphosphate, bcl2l11, B-cell lymphoma-2-like protein 11, TCDD, 2,3,7,8-Tetrachlorodibenzodioxin, RNA - Ribonucleic acid, lncRNAs, Long non-coding RNA, NFKBAP, NFKB Activating protein-1, COPD, Chronic obstructive pulmonary disease, PM2.5, Particulate Matter2.5, Environment, WHO, World Health Organization, 03 medical and health sciences, MRE, MicroRNA Response Elements, microRNA, SPIONs, Superparamagnetic Iron Oxide Nanoparticles, AMPK, Adenosine Monophosphate-activated protein kinase, lcsh:Toxicology. Poisons, NASH, Non-alcoholic steatohepatitis, CDK, Cyclin-dependent Kinase, CEC, Contaminants of Emerging Concern, RNase III, Ribonuclease III, LRP-1-, Low density lipoprotein receptor-related protein 1, MC-LR, Microcystin-Leucine Arginine, CCNB1, Cyclin B1, Ag, Silver, SiO2, Silicon dioxide, chemistry, LIN28B, Lin-28 homolog B, TRBP, Transactivation Response RNA Binding Protein, 030217 neurology & neurosurgery, Ahr aryl hydrocarbon receptor, Biomarkers, COX2, Cyclooxygenase-2, Au, Gold, ZEA, Zearalanone, Mn, Manganese, NF- ҡB, Nuclear Factor kappa-light-chain-enhancer of activated B cells, Health, Toxicology and Mutagenesis, Grp78/BIP, Binding immunoglobulin protein, 010501 environmental sciences, UTR, Untranslated region, chemistry.chemical_compound, ARRB1, Arrestin beta 1, RISC, RNA-induced silencing complex, Zn, Zinc, CTGF, Connective Tissue Growth Factor, NET1, Neuroepithelial Cell Transforming 1, BNIP3−3, BCL2/adenovirus E1B 19 kDa protein-interacting protein 3, DNA, Deoxy ribonucleic acid, PFAS, Poly-fluoroalkyl substances, mRNA, Messenger RNA, ripk 1, Receptor-interacting serine/threonine-protein kinase 1, Toxicity, Fadd, Fas-associated protein with death domain, IL-6, Interleukin 6, SOLiD, Sequencing by Oligonucleotide Ligation and Detection, Al2O3, Aluminium oxide, ceRNA, Competing endogenous RNA, Computational biology, Biology, SEMA6D, Semaphorin-6D, BCB, Blood-cerebrospinal fluid barrier, ADAMTS9, A disintegrin and metalloproteinase with thrombospondin motifs 9, CDC25A, M-phase inducer phosphatase 1, lcsh:RA1190-1270, CDK1, Cyclin-dependent kinase 1, DON, Deoxynivalenol, RNA, Ribonucleic acid, TNF-α, Tumor necrosis factor – alpha, 0105 earth and related environmental sciences, ComputingMethodologies_COMPUTERGRAPHICS, miRNA, MicroRNA, MAPK, Mitogen Activated Protein Kinase, Gene regulation, CDC25C, M-phase inducer phosphatase 3, Xenobiotic, MiRNA biogenesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9ee14a85356d66a24aeb2b5ac399f7Test
https://pubmed.ncbi.nlm.nih.gov/32426239Test

المؤلفون: Xinfang Yu, Li Zhou, Qi Liang, Haidan Liu, Wenbin Liu, Wei Li

المصدر: EBioMedicine, Vol 26, Iss C, Pp 100-111 (2017)
EBioMedicine

مصطلحات موضوعية: 0301 basic medicine, Esophageal Neoplasms, lcsh:Medicine, Apoptosis, DMSO, dimethyl sulphoxide, chemistry.chemical_compound, Mice, 0302 clinical medicine, ESCC, esophageal squamous cell carcinoma, shRNA, short nairpin RNA, Aurora Kinase B, Enzyme Inhibitors, Aurora B, Deguelin, lcsh:R5-920, General Medicine, Cell biology, Gene Expression Regulation, Neoplastic, 030220 oncology & carcinogenesis, Gene Knockdown Techniques, embryonic structures, Carcinoma, Squamous Cell, biological phenomena, cell phenomena, and immunity, lcsh:Medicine (General), Research Paper, RNase A, ribonuclease A, Aurora B kinase, Aurora inhibitor, Mitosis, macromolecular substances, Biology, General Biochemistry, Genetics and Molecular Biology, OS, overall survival, 03 medical and health sciences, Histone H3, Esophageal squamous cell carcinoma, Cell Line, Tumor, Rotenone, Animals, Humans, Cell Proliferation, Cell growth, lcsh:R, Xenograft Model Antitumor Assays, digestive system diseases, enzymes and coenzymes (carbohydrates), 030104 developmental biology, chemistry, Cancer research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f28f346d26a2d2d766c884eb7b8bc07Test
http://www.sciencedirect.com/science/article/pii/S235239641730436XTest

المؤلفون: Madhu, Kollareddy, Alice, Sherrard, Ji Hyun, Park, Marianna, Szemes, Kelli, Gallacher, Zsombor, Melegh, Sebastian, Oltean, Martin, Michaelis, Jindrich, Cinatl, Abderrahmane, Kaidi, Karim, Malik

المصدر: Cancer Letters

مصطلحات موضوعية: Prometaphase, Indoles, Time Factors, Paclitaxel, RNase A, ribonuclease A, ERK, extracellular signal-regulated kinases, Mitosis, MTT, 3-(4,5-Dimethylthiazol-2-Yl)-2,5-Diphenyltetrazolium Bromide, Apoptosis, Spindle Apparatus, Antimitotic Agents, Transfection, Inhibitory Concentration 50, Neuroblastoma, MEK, Mitogen-activated protein kinase kinase, Cell Line, Tumor, Antineoplastic Combined Chemotherapy Protocols, TERT, Telomerase reverse transcriptase, Humans, Chemotherapy, Kinetochores, Protein Kinase Inhibitors, ALK, Anaplastic Lymphoma kinase, QVD, quinolyl-valyl-O-methylaspartyl-(-2,6-difluorophenoxy)- methyl ketone, Aurora Kinase A, GFP, green fluorescent protein, YK-4-279, Drug resistance/synergy, Dose-Response Relationship, Drug, Cell Cycle, SDS-PAGE, sodium-dodecyl sulphate-polyacrylamide gel electrophoresis, Drug Synergism, Azepines, PBS, Phosphate-buffered saline, Drug Resistance, Multiple, Pyrimidines, Drug Resistance, Neoplasm, Vincristine, EGF, Epidermal growth factor, kDa, kilodaltons, RNA Interference, Original Article, Tumor Suppressor Protein p53, pHH3, phospho-histone H3 (ser10), MAPK, mitogen-activated protein kinase, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::2608aeba939880ca4cd0d199842c863bTest
https://pubmed.ncbi.nlm.nih.gov/28602975Test

المؤلفون: Koji Yokoyama, Yuichi Koga, Dong-Ju You, Shigenori Kanaya, Elias Tannous

المصدر: FEBS Open Bio

مصطلحات موضوعية: RNase H, Circular dichroism, N-terminal domain, RNase P, Salt-dependent folding, Salt (chemistry), Halo-RNH1, RNase H1 from Halobacterium sp. NRC-1, Halobacterium, Article, General Biochemistry, Genetics and Molecular Biology, Hydrophobic effect, chemistry.chemical_classification, biology, Active site, Divalent metal ions, biology.organism_classification, Halo-CTD, C-terminal domain (residues 69–199) of Halo-RNH1, Halobacterium sp. NRC-1, GdnHCl, guanidine hydrochloride, Folding (chemistry), Halo-NTD, N-terminal domain (residues 1–68) of Halo-RNH1, Crystallography, RNase H, ribonuclease H, chemistry, biology.protein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36ece5b119d9b242055f0494406d748Test
https://doi.org/10.1016/j.fob.2012.10.003Test

المؤلفون: Ray K.M. Leung, Paul A. Whittaker

المصدر: Pharmacology & Therapeutics

مصطلحات موضوعية: Small interfering RNA, K-Ras, c-Kirsten-ras protein, Respiratory Tract Diseases, MIP2, macrophage inflammatory protein-2, MDR, multidrug-resistance protein, miRNA, microRNAs, ABCA1, ATP-binding cassette, subfamily A, member 1, Small hairpin RNA, AAV, adeno-associated virus, shRNA, RNA interference, Neoplasms, Validation, CXCR4, chemokine (C–X–C motif), receptor 4, RasGAP, Ras GTPase-activating protein, RISC, RNA-induced silencing complex, TGFβ, transforming growth factor β, Disease, CML, chronic myelogenous leukemia, Pharmacology (medical), RNA, Small Interfering, Genetics, Gene knockdown, RdDM, RNA-directed DNA methylation, CD8, T-lymphocyte differentiation antigen T8/Leu-2, smad 7, mothers against decapentaplegic homolog 7, VEGF, vascular endothelial growth factor, Cell biology, HIV, human immunodeficiency virus, LoxP, locus χ of crossover P1, RNA silencing, RNAi, RNA interference, Rnase III, ribonuclease III, SCID, severe combined immunodeficiency, HCV, hepatitis C virus, TNFα, tumour necrosis factor α, EpCAM, tumour-associated calcium signal transducer 1, S1P, sphingosine 1-phosphate, shRNA, short hairpin RNA, LPS, lipopolysaccharide, RNA Interference, TGFα, transforming growth factor α, TLR3, toll-like receptor 3, Cre, causes recombination, LacZ, β-galactosidase α-peptide, CCR5, chemokine (C–C motif) receptor 5, Biology, KC, keratinocyte-derived chemokine, Communicable Diseases, Article, LNA, locked nucleic acid, NF-κB, Nuclear factor-kappaB, B-RAF, murine sarcoma viral (v-raf) oncogene homolog B1 oncogene, Fas, tumour necrosis factor receptor superfamily, member 6, microRNA, Animals, Humans, BCR-ABL, breakpoint cluster region-protooncogene tyrosine-protein kinase ABL1 fusion protein, Gene silencing, IFN, interferon, Gene Silencing, SARS, severe acute respiratory syndrome, PEG, polyethylene glycol, PEI, polyethyleneimine, Pharmacology, Bcl-2, B-cell chronic lymphocytic leukemia/lymphoma 2, EC, endothelial cell, BMP4, bone morphogenetic protein 4, RNA, EGFR, epidermal growth factor receptor, bp, base pairs, PKR, dsRNA-dependent protein kinase, HBV, hepatitis B virus, COPD, chronic obstructive pulmonary disease, siRNA, small interfering RNA, Drug Design, RNAi, siRNA, dsRNA, double-stranded RNA, Therapy, RSV, respiratory syncytial virus, ERK, extracellular signal regulated protein kinase, smad 1, mothers against decapentaplegic homolog 1, MAPK, mitogen-activated protein kinase, HMG-CoA, beta-hydroxy-beta-methylglutaryl coenzyme A

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dee73333d21169d5133ab57939122a4Test
https://doi.org/10.1016/j.pharmthera.2005.03.004Test

المؤلفون: Cecília M. Arraiano, Nabila Haddad, Margarida Saramago, Hervé Prévost, Rute G. Matos

المساهمون: UMR 1014 SECurité des ALIments et Microbiologie, Institut National de la Recherche Agronomique (INRA)-Ecole Nationale Vétérinaire, Agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS), Universidade Nova de Lisboa = NOVA University Lisbon (NOVA), Region Pays de la Loire through the programme grant GENICAMP, GENICAMP programme, Institut National de la Recherche Agronomique and Region des Pays de la Loire, Fundacao para a Ciencia e Tecnologia (FCT) [PEst-OE/EQB/LA0004/2011, PTDC/QUI-BIQ/111757/2009], FCT [SFRH/BD/65607/2009, SFRH/BPD/75887/2011]

المصدر: Bioscience Reports
Bioscience Reports, Portland Press, 2013, 33 (6), pp.889-901. ⟨10.1042/BSR20130090⟩
Bioscience Reports 6 (33), 889-901. (2013)
Bioscience Reports, Vol 33, Iss 6, p e00082 (2013)

مصطلحات موضوعية: Ribonuclease III, RNase III, Cj-RNase III, C. jejuni RNase III, [SDV]Life Sciences [q-bio], lcsh:Life, lcsh:QR1-502, dsRBD, dsRNA binding domain, DSS, disuccinimidyl suberate, medicine.disease_cause, Biochemistry, RNase PH, RNase III, ribonuclease III, lcsh:Microbiology, Enzyme Stability, Magnesium, Conserved Sequence, Phylogeny, 0303 health sciences, biology, Hydrogen-Ion Concentration, Ec-RNase III, E. coli RNase III, RNA, Bacterial, LB, Luria–Bertani, manganese, ribonuclease, wt, wild-type, Molecular Sequence Data, Biophysics, catalytic activity, Campylobacter jejuni, S2, Microbiology, 03 medical and health sciences, Bacterial Proteins, medicine, Escherichia coli, Ribonuclease, Polynucleotide phosphorylase, Amino Acid Sequence, RRNA processing, Protein Structure, Quaternary, Molecular Biology, 030304 developmental biology, RNA Cleavage, Original Paper, Base Sequence, 030306 microbiology, Genetic Complementation Test, Cell Biology, biology.organism_classification, PNPase, polynucleotide phosphorylase, cpm, counts/min, RNase MRP, lcsh:QH501-531, Amino Acid Substitution, DTT, dithiothreitol, RNA, Ribosomal, biology.protein, Mutagenesis, Site-Directed, Calcium

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f605e6af3db686457b4409b63c48f5Test
https://hal.inrae.fr/hal-02646558/file/Haddad_2013_1.pdfTest

المؤلفون: Setsuko Ando, Beena G. Singh, Kyoko Takayama, Masato Noguchi, Yurika Kubo, Katsuhiko Fujio, K. Indira Priyadarsini, Michio Iwaoka, Kenta Arai

المصدر: FEBS Open Bio

مصطلحات موضوعية: Steric effects, Circular dichroism, pI, isoelectric point, R°, reduced CX-397 at acidic conditions, RNase A, ribonuclease A, Rlx-A, relaxin A-chain, Oxidative folding, 1S, 2S, 3S, and 4S, ensembles of SS intermediates with one, two, three, and four SS bonds, respectively, DTTred, dl-dithiothreitol, Article, HV-3, recombinant hirudin variant-3, General Biochemistry, Genetics and Molecular Biology, Dithiothreitol, 1S°, 2S°, and 3S°, ensembles of SS intermediates of CX-397 with one, two, and three kinetically formed SS bonds, respectively, N, native protein, TFA, trifluoroacetic acid, chemistry.chemical_compound, Disulfide, Reaction rate constant, DHSox, trans-3,4-dihydroxyselenolane oxide, Gdn-HCl, guanidine hydrochloride, Organic chemistry, Ins-B, insulin B-chain, Reactivity (chemistry), DTTox, oxidized dithiothreitol, SeSe, diselenide, CD, circular dichroism, trans-3, ESI, electron spray ionization, Ins-A, insulin A-chain, GSSG, oxidized glutathione, 4-Dihydroxyselenolane oxide, Substrate (chemistry), S−, thiolate, DHSred, reduced DHSox, Tris, tris(hydroxymethyl)aminomethane, CX-397, recombinant hirudin variant CX-397, HV-1, recombinant hirudin variant-1, R, reduced polypeptide, Crystallography, Isoelectric point, chemistry, HPLC, high-performance liquid chromatography, SS, disulfide, NHE, normal hydrogen electrode, SH, thiol, AEMTS, 2-aminoethyl methanethiosulfonate, Redox potential

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de20d9ac2280b5ec3b3da4a90574900cTest

المؤلفون: K. Ravi Acharya, Nethaji Thiyagarajan

المصدر: FEBS Open Bio
Thiyagarajan, N & Acharya, K R 2013, ' Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule ', FEBS Open Bio, vol. 3, pp. 65-70 . https://doi.org/10.1016/j.fob.2012.12.003Test

مصطلحات موضوعية: Angiogenin, RNase P, Ribonuclease inhibitor, RI -, ribonuclease inhibitor, Conformational flexibility, Article, General Biochemistry, Genetics and Molecular Biology, SDG 3 - Good Health and Well-being, EDN -, eosinophil derived neurotoxin, Ribonuclease A, RNase A, - ribonuclease A, Peptide sequence, Eosinophil derived neurotoxin, chemistry.chemical_classification, biology, Crystal structure, Active site, RNA, Protein engineering, Enzyme, Biochemistry, chemistry, biology.protein, AEH -, angiogenin–eosinophil derived neurotoxin hybrid, ANG, - Human angiogenin

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45a2da70e188445465b6c4604d7aa5eTest