المؤلفون: Gapińska, Marta, Zajko, Weronika, Skowronek, Krzysztof, Figiel, Małgorzata, Krawczyk, Paweł S, Egorov, Artyom A, Dziembowski, Andrzej, Johansson, Marcus J O, Nowotny, Marcin

المصدر: Nucleic Acids Research. 52(8):4723-4738

مصطلحات موضوعية: Bacteriophages/genetics, Lactococcus/virology, Models, Molecular, Bacterial Proteins/metabolism, Crystallography, X-Ray, Protein Domains, RNA-Directed DNA Polymerase/metabolism, Protein Multimerization, Structure-Activity Relationship, Naturvetenskap, Biologi, Biokemi och molekylärbiologi, Natural Sciences, Biological Sciences, Biochemistry and Molecular Biology, Medicin och hälsovetenskap, Medicinska och farmaceutiska grundvetenskaper, Mikrobiologi inom det medicinska området, Medical and Health Sciences, Basic Medicine, Microbiology in the medical area

الوصول الحر: https://lup.lub.lu.se/record/bf11b2f4-8f6b-4efd-a44d-0b87a9b9e3a2Test
http://dx.doi.org/10.1093/nar/gkae230Test

المؤلفون: Elmessaoudi-Idrissi, Mohcine, Blondel, Arnaud, Kettani, Anass, Windisch, Marc, P, Benjelloun, Soumaya, Ezzikouri, Sayeh

المساهمون: Université Hassan II Casablanca (UH2MC), Laboratoire des Hépatites Virales Casablanca, Maroc (LHV), Institut Pasteur du Maroc, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Bioinformatique structurale - Structural Bioinformatics, Institut Pasteur Paris (IP)-Centre National de la Recherche Scientifique (CNRS), Hepatitis Research Laboratory Corée du Sud, Institut Pasteur Korea - Institut Pasteur de Corée

المصدر: ISSN: 0929-8673.

مصطلحات موضوعية: Ligand-based virtual screening, Hepatitis B Virus, quantitative structure-activity rela- tionships, docking, structure-based virtual screening, workflow, inhibitors, MESH: Antiviral Agents/chemistry, MESH: Antiviral Agents/pharmacology, MESH: RNA-Directed DNA Polymerase/chemistry, MESH: RNA-Directed DNA Polymerase/metabolism, MESH: Symporters/metabolism, MESH: Symporters/antagonists & inhibitors, MESH: Trans-Activators/antagonists & inhibitors, MESH: Antiviral Agents/therapeutic use, MESH: Trans-Activators/metabolism, MESH: Capsid Proteins/antagonists & inhibitors, MESH: Capsid Proteins/metabolism, MESH: Hepatitis B/drug therapy, MESH: Hepatitis B/virology, MESH: Hepatitis B/pathology, MESH: Hepatitis B virus/drug effects, MESH: Humans, MESH: Hepatitis B virus/metabolism, MESH: Molecular Docking Simulation, MESH: Organic Anion Transporters, Sodium-Dependent/antagonists & inhibitors, Sodium-Dependent/metabolism, MESH: Quantitative Structure-Activity Relationship, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM]

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/29473495; pasteur-02528562; https://pasteur.hal.science/pasteur-02528562Test; https://pasteur.hal.science/pasteur-02528562/documentTest; https://pasteur.hal.science/pasteur-02528562/file/20170706_VS_Review_AB3b_SE2_MW_SE3-acc.pdfTest; PUBMED: 29473495

الإتاحة: https://doi.org/10.2174/0929867325666180221141451Test
https://pasteur.hal.science/pasteur-02528562Test
https://pasteur.hal.science/pasteur-02528562/documentTest
https://pasteur.hal.science/pasteur-02528562/file/20170706_VS_Review_AB3b_SE2_MW_SE3-acc.pdfTest

المؤلفون: Kubina, Julie, Geldreich, Angèle, GALES, Jón Pol, Baumberger, Nicolas, Bouton, Clément, Ryabova, Lyubov A, Grasser, Klaus D, Keller, Mario, Dimitrova, Maria

المصدر: Nucleic Acids Research, 49 (15), 8900 - 8922 (2021-09-07)

مصطلحات موضوعية: 5' Untranslated Regions, Arabidopsis Proteins, Capsid Proteins, RNA, Messenger, Viral, Viral Proteins, RNA-Directed DNA Polymerase, Active Transport, Cell Nucleus, Arabidopsis/virology, Arabidopsis Proteins/metabolism, Arabidopsis Proteins/physiology, Capsid Proteins/metabolism, Caulimovirus/genetics, Caulimovirus/metabolism, Cell Nucleus/metabolism, Cell Nucleus/virology, Plant Diseases/virology, Messenger/metabolism, Viral/chemistry, Viral/metabolism, RNA-Directed DNA Polymerase/metabolism, Viral Proteins/metabolism, Arabidopsis, Caulimovirus, Plant Diseases, Genetics, Life sciences, Biochemistry

العلاقة: http://academic.oup.com/nar/article-pdf/49/15/8900/40083279/gkab653.pdfTest; urn:issn:0305-1048; urn:issn:1362-4962; https://orbilu.uni.lu/handle/10993/57143Test; info:hdl:10993/57143; scopus-id:2-s2.0-85116172004; info:pmid:34370034; wos:000697383500038

الإتاحة: https://doi.org/10.1093/nar/gkab653Test
https://orbilu.uni.lu/handle/10993/57143Test

المساهمون: Chunkyu Ko, Youn-Chul Shin, Woo-Jin Park, Seungtaek Kim, Jonghwa Kim, Wang-Shick Ryu, Kim, Seung Taek

المصدر: T201400335.pdf

مصطلحات موضوعية: Arginine/metabolism, Aspartic Acid/metabolism, DNA, Viral/biosynthesis, Hep G2 Cells, Hepatitis B virus/enzymology, Hepatitis B virus/genetics, Humans, Mutation, RNA-Directed DNA Polymerase/chemistry, RNA-Directed DNA Polymerase/metabolism, Ribonuclease H/chemistry, Ribonuclease H/genetics, Ribonuclease H/metabolism

وصف الملف: 154~163

العلاقة: JOURNAL OF VIROLOGY; J01930; OAK-2014-00209; https://ir.ymlib.yonsei.ac.kr/handle/22282913/98129Test; T201400335; JOURNAL OF VIROLOGY, Vol.88(1) : 154-163, 2014

الإتاحة: https://doi.org/10.1128/JVI.01916-13Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/98129Test

المؤلفون: Doucet, A., Hulme, A., Sahinovic, E., Kulpa, D., Moldovan, J., Kopera, H., Athanikar, J., Hasnaoui, M., Bucheton, A., Morvan, J., Gilbert, N.

المساهمون: Institut de génétique humaine (IGH), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), University of Michigan Medical School Ann Arbor, University of Michigan Ann Arbor, University of Michigan System-University of Michigan System, Howard Hughes Medical Institute Chevy Chase (HHMI), Howard Hughes Medical Institute (HHMI), AJD was the recipient of fellowships from the French government (Ministère de l'Enseignement Supérieur et de la Recherche), from the Association pour la Recherche contre le Cancer (ARC), and from the Fondation Recherche Medicale (FRM). AEH and DAK were supported in part by a Michigan Predoctoral Training Grant from the National Institutes of Health (5T32GM07544). AEH also was supported by a Rackham Predoctoral Fellowship. JNA was supported in part by a NRSA postdoctoral fellowship (F32GM20859). HCK was supported in part by an American Cancer Society postdoctoral fellowship (PF-07-059-01-GMC). Work in the laboratory of NG is supported by the Centre National de Recherche Scientifique and the Agence Nationale de la Recherche (ANR-05-JCJC-0120). Work in the laboratory of JVM is supported by an NIH grant (GM060518). The University of Michigan Cancer Center Support Grant (5P30CA46592) helped defray some of the sequencing costs incurred during this study. JVM is an investigator of the Howard Hughes Medical Institute., We thank Christine Beck, José Luis Garcia Perez, Billy Giblin, Sandra Richardson, Séverine Chambeyron, Alain Pélisson, and Oliver Weichenrieder for helpful comments during the course of this study. We thank Edouard Bertrand, Thomas Fanning, John Goodier, Greg Hannon, and Jamal Tazi for generously providing reagents. We thank the IGH and University of Michigan Sequencing Cores for help with DNA sequencing. We are grateful to Eugenia Basyuk (FISH), Christelle Cayrou, Bijan Sobhian (purification protocols), and Séverine Chambeyron (fluorescence analysis) for assistance in designing/implementing experiments. We thank Nicole Lautredou (Montpellier RIO Imaging) and Chris Edwards (Microscopy and Image-analysis Laboratory at the University of Michigan, Department of Cell and Developmental Biology) for assistance with confocal microscopy.

المصدر: ISSN: 1553-7390.

مصطلحات موضوعية: MESH: Binding Sites/genetics, MESH: Blotting, Western, MESH: Humans, MESH: In Situ Hybridization, Fluorescence, MESH: Mutagenesis, Insertional, MESH: Long Interspersed Nucleotide Elements/genetics, MESH: Mutation, MESH: Open Reading Frames/genetics, MESH: Plasmids/genetics, MESH: RNA/metabolism, MESH: RNA-Directed DNA Polymerase/genetics, MESH: RNA-Directed DNA Polymerase/metabolism, MESH: Ribonucleoproteins/genetics, MESH: Reverse Transcriptase Polymerase Chain Reaction, MESH: Ribonucleoproteins/metabolism, MESH: Cell Line, Tumor, MESH: Transfection, MESH: Cytoplasm/metabolism, MESH: Gene Expression, MESH: HEK293 Cells, MESH: HeLa Cells, [SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human genetics

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/20949108; hal-00527796; https://hal.science/hal-00527796Test; https://hal.science/hal-00527796/documentTest; https://hal.science/hal-00527796/file/Characterization_of_LINE1_Ribonucleoprotein_Particles.PDFTest; PUBMED: 20949108; PUBMEDCENTRAL: PMC2951350

الإتاحة: https://doi.org/10.1371/journal.pgen.1001150Test
https://hal.science/hal-00527796Test
https://hal.science/hal-00527796/documentTest
https://hal.science/hal-00527796/file/Characterization_of_LINE1_Ribonucleoprotein_Particles.PDFTest

المؤلفون: Osland, A, Shammas, F V, Heikkilä, R

المصدر: Tidsskrift for Den Norske Laegeforening. 116(6):726

المؤلفون: Held, W., Waanders, G.A., Acha-Orbea, H., MacDonald, H.R.

المصدر: Journal of Experimental Medicine, vol. 180, no. 6, pp. 2347-2351

مصطلحات موضوعية: Animals, B-Lymphocytes/drug effects, B-Lymphocytes/immunology, CD4-Positive T-Lymphocytes/immunology, CD4-Positive T-Lymphocytes/virology, DNA, Viral/analysis, Viral/biosynthesis, Kinetics, Lymph Nodes/immunology, Lymph Nodes/virology, Mammary Tumor Virus, Mouse/drug effects, Mouse/pathogenicity, Mice, Inbred BALB C, Inbred Strains, Phenotype, Polymerase Chain Reaction, RNA-Directed DNA Polymerase/metabolism, Superantigens/biosynthesis, T-Lymphocytes/drug effects, T-Lymphocytes/immunology, Virus Replication/drug effects, Zidovudine/pharmacology

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/7525852; info:eu-repo/semantics/altIdentifier/pissn/0022-1007; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_624FE703C8B81; https://serval.unil.ch/notice/serval:BIB_624FE703C8B8Test; urn:issn:0022-1007; https://serval.unil.ch/resource/serval:BIB_624FE703C8B8.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_624FE703C8B81Test

الإتاحة: https://doi.org/10.1084/jem.180.6.2347Test
https://serval.unil.ch/notice/serval:BIB_624FE703C8B8Test
https://serval.unil.ch/resource/serval:BIB_624FE703C8B8.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_624FE703C8B81Test

المؤلفون: Mohcine Elmessaoudi-Idrissi, Arnaud Blondel, Anass Kettani, Marc P. Windisch, Sayeh Ezzikouri, Soumaya Benjelloun

المساهمون: Université Hassan II [Casablanca] (UH2MC), Laboratoire des Hépatites Virales [Casablanca, Maroc] (LHV), Institut Pasteur du Maroc, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Bioinformatique structurale, Institut Pasteur [Paris]-Centre National de la Recherche Scientifique (CNRS), Hepatitis Research Laboratory [Corée du Sud], Institut Pasteur de Corée, Bioinformatique structurale - Structural Bioinformatics, Institut Pasteur Korea - Institut Pasteur de Corée, Institut Pasteur [Paris] (IP)-Centre National de la Recherche Scientifique (CNRS)

المصدر: Current Medicinal Chemistry
Current Medicinal Chemistry, Bentham Science Publishers, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩
Current Medicinal Chemistry, 2018, 25 (23), pp.2709-2721. ⟨10.2174/0929867325666180221141451⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: Organic Anion Transporters, Sodium-Dependent/antagonists & inhibitors, Quantitative Structure-Activity Relationship, 02 engineering and technology, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, MESH: Hepatitis B/virology, medicine.disease_cause, Bioinformatics, Biochemistry, MESH: Capsid Proteins/metabolism, Virological response, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Drug Discovery, inhibitors, Global health, Medicine, Viral Regulatory and Accessory Proteins, MESH: Hepatitis B virus/drug effects, media_common, MESH: Quantitative Structure-Activity Relationship, [SDV.BBM.BS]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Structural Biology [q-bio.BM], Symporters, Drug discovery, MESH: Symporters/metabolism, RNA-Directed DNA Polymerase, MESH: Antiviral Agents/pharmacology, Hepatitis B, 3. Good health, Molecular Docking Simulation, MESH: Hepatitis B/pathology, Ligand-based virtual screening, docking, MESH: Molecular Docking Simulation, MESH: Organic Anion Transporters, Sodium-Dependent/metabolism, Molecular Medicine, [CHIM.CHEM]Chemical Sciences/Cheminformatics, Drug, Hepatitis B virus, structure-based virtual screening, workflow, media_common.quotation_subject, 0206 medical engineering, Alpha interferon, Organic Anion Transporters, Sodium-Dependent, Antiviral Agents, 03 medical and health sciences, MESH: Trans-Activators/metabolism, Humans, MESH: Capsid Proteins/antagonists & inhibitors, Pharmacology, Virtual screening, MESH: Humans, business.industry, quantitative structure-activity rela- tionships, MESH: Hepatitis B virus/metabolism, Organic Chemistry, Clinical trial, 030104 developmental biology, MESH: Hepatitis B/drug therapy, MESH: RNA-Directed DNA Polymerase/metabolism, MESH: Antiviral Agents/therapeutic use, Trans-Activators, Capsid Proteins, [INFO.INFO-BI]Computer Science [cs]/Bioinformatics [q-bio.QM], MESH: Antiviral Agents/chemistry, MESH: RNA-Directed DNA Polymerase/chemistry, business, 020602 bioinformatics, MESH: Symporters/antagonists & inhibitors, MESH: Trans-Activators/antagonists & inhibitors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5619f110d1c8caa76ef3dfca0e7a17e0Test
https://pubmed.ncbi.nlm.nih.gov/29473495Test

المؤلفون: Flodell, Sara, Schleucher, Jurgen, Cromsigt, Jenny, Ippel, Hans, Kidd-Ljunggren, Karin, Wijmenga, Sybren

المصدر: Nucleic Acids Research. 30(21):4803-4811

مصطلحات موضوعية: Base Pairing, Base Sequence, Genome, Viral, Genotype, Hepatitis B virus/classification/enzymology/*genetics, Humans, Mutation, Nuclear Magnetic Resonance, Biomolecular, Nucleic Acid Conformation, Pyrimidines/*metabolism, RNA, Viral/*chemistry/genetics/*metabolism, RNA-Directed DNA Polymerase/metabolism, Substrate Specificity, Uridine/metabolism, MEDICINE, MEDICIN

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-10293Test
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=12409471&dopt=CitationTest

المؤلفون: Christine Chaponnier, Ulrich Hübscher, Oleg Georgiev, Walter Schaffner, K. Gramatikoff, Michael O. Hottiger

المساهمون: University of Zurich, Hübscher, U

المصدر: Nucleic Acids Research, Vol. 23, No 5 (1995) pp. 736-741

مصطلحات موضوعية: Actins/ metabolism, DNA, Complementary, Recombinant Fusion Proteins, Protein subunit, Molecular Sequence Data, Gene Products, gag, macromolecular substances, Plasma protein binding, ddc:616.07, Biology, gag Gene Products, Human Immunodeficiency Virus, 1311 Genetics, Complementary DNA, RNA-Directed DNA Polymerase/ metabolism, Genetics, Animals, Humans, Beta-actin, HIV-1/ enzymology, Protein Precursors, Gene Products, gag/metabolism, Actin, Glutathione Transferase, DNA Primers, Base Sequence, RNA-Directed DNA Polymerase, Protein Precursors/metabolism, 10226 Department of Molecular Mechanisms of Disease, Fusion protein, Molecular biology, Actins, HIV Reverse Transcriptase, Reverse transcriptase, pol Gene Products, Human Immunodeficiency Virus, HIV-1, 570 Life sciences, biology, Cattle, Glutathione Transferase/metabolism, Recombinant Fusion Proteins/metabolism, Protein Processing, Post-Translational, Protein Binding

وصف الملف: Large_subunit.pdf - application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a28dda31c22ed59532434cc66d5e6d61Test
https://doi.org/10.1093/nar/23.5.736Test