المؤلفون: Harri A. Järveläinen, Christian Schmithals, Maike von Harten, Bianca Kakoschky, Thomas J. Vogl, Stephen Harris, Claire Henson, Gemma Bullen-Clerkson, Albrecht Piiper

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 6; Pages: 5700

مصطلحات موضوعية: CEND-1, iRGD peptide, LSTA1, certepetide, pharmacokinetics, quantitative whole-body autoradiography (QWBA), quantitative radioactivity analysis (QRA)

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Oncology; https://dx.doi.org/10.3390/ijms24065700Test

الإتاحة: https://doi.org/10.3390/ijms24065700Test

المؤلفون: Vervaeke, P., Borgos, Sven Even F., Sanders, N.N., Combes, Francis

المصدر: 1-17 ; 184 ; Advanced Drug Delivery Reviews ; 114236

مصطلحات موضوعية: Moderna, Spikevax, Pfizer/BioNTech, Comirnatmy, Lumasiran, Oxlumo, Inclisiran, Leqvio, Givosiran, Givlaari, Patisiran, Onpattro, Regulatory, Mass spectrometry, bDNA, FISH, RT-qPCR, QWBA, BLI, FLI, Imaging, LNP, Lipid nanoparticle, Vaccine, mRNA, siRNA, RNA therapeutic, Distribution, Biodistribution, Guidelines

وصف الملف: application/pdf

العلاقة: Advanced Drug Delivery Reviews. 2022, 184 1-17.; urn:issn:0169-409X; https://hdl.handle.net/11250/3010571Test; https://doi.org/10.1016/j.addr.2022.114236Test; cristin:2026803

الإتاحة: https://doi.org/10.1016/j.addr.2022.114236Test
https://hdl.handle.net/11250/3010571Test

المؤلفون: Tohru Hirato, Kohtaro Minami, Masafumi Kinoshita, Eiji Yoden, Atsushi Imakiire, Ryuji Yamamoto, Noboru Tanaka

المصدر: Molecular Genetics and Metabolism Reports, Vol 27, Iss, Pp 100758-(2021)
Molecular Genetics and Metabolism Reports

مصطلحات موضوعية: Medicine (General), Complement-dependent cytotoxicity, MPS II, mucopolysaccharidosis type II, MCHC, mean corpuscular hemoglobin concentration, Pharmacology, GAG, glycosaminoglycan, CSF, cerebrospinal fluid, Endocrinology, QWBA, quantitative whole-body autoradioluminography, Effector function, pAb, polyclonal antibody, Antibody-dependent cellular cytotoxicity, Mucopolysaccharidosis type II, Biology (General), TK, toxicokinetics, chemistry.chemical_classification, Antibody-dependent cell-mediated cytotoxicity, Hunter syndrome, RBC, red blood cell, Ret, reticulocyte, Toxicity, ADA, anti-drug antibody, Research Paper, BBB, blood-brain barrier, QH301-705.5, MCH, mean corpuscular hemoglobin, IDS, iduronate-2-sulfatase, NOAEL, no observed adverse effect level, Transferrin receptor, TfR, transferrin receptor, CNS, central nervous system, Ht, hematocrit, R5-920, ERT, enzyme-replacement therapy, Tf, transferrin, Genetics, medicine, mAb, monoclonal antibody, CDC, complement-dependent cytotoxicity, Molecular Biology, FOB, functional observational battery, ADCC, antibody-dependent cellular cytotoxicity, business.industry, Iduronate-2-sulfatase, medicine.disease, Anti-transferrin receptor antibody, chemistry, Transferrin, Fc, fragment crystalizable, business, Hb, hemoglobin

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bad9d33274408b77250340e21baeffTest
http://www.sciencedirect.com/science/article/pii/S2214426921000525Test

المؤلفون: Jenny Tobin, Albert T. Profy, Ali R. Banijamali, Mark G. Currie, James Wakefield, Jaime L. Masferrer, G. Todd Milne, Daniel P. Zimmer, Andrew Carvalho, Peter Germano, Barden Timothy Claude

المصدر: Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 8, Iss 2, Pp n/a-n/a (2020)

مصطلحات موضوعية: Male, medicine.medical_specialty, sGC, Metabolite, praliciguat, Glucuronidation, Adipose tissue, RM1-950, 030226 pharmacology & pharmacy, Excretion, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Feces, 0302 clinical medicine, Soluble Guanylyl Cyclase, Pharmacokinetics, Oral administration, nitric oxide, Internal medicine, QWBA, medicine, Animals, Bile, Rats, Long-Evans, Tissue Distribution, General Pharmacology, Toxicology and Pharmaceutics, Original Articles, Bioavailability, cGMP, Endocrinology, Pyrimidines, Neurology, chemistry, 030220 oncology & carcinogenesis, Pyrazoles, Original Article, excretion, Therapeutics. Pharmacology, absorption, metabolism, pharmacokinetics, Drug metabolism, mass balance

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b3e4df24159164c127118e8e21c0b4Test
http://europepmc.org/articles/PMC7171252Test

المؤلفون: Joel Krauser, Esther van de Kerkhof, Frédéric Lozac'h, Alexandre Catoire, Thomas Faller, Jesper Christensen, Piet Swart, Karine Litherland, Francois Natt, Jürg Hunziker, Maxime Garnier

المصدر: Pharmacology Research & Perspectives

مصطلحات موضوعية: 0301 basic medicine, Uracil, Cytidine, Original Articles, Pharmacology, 2′‐O‐methyluridine, lithium adducts formation, Uridine, Excretion, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Neurology, chemistry, Pharmacokinetics, ADME, QWBA, SiRNA, Original Article, General Pharmacology, Toxicology and Pharmaceutics, Nucleoside, Cytosine, mass spectrometry

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b71cf5c11f6d9a383a30b18ac695f4aTest
https://doi.org/10.1002/prp2.209Test

المؤلفون: Caroline Sychterz, Andrew Weber, Andrew W Harrell, Kitaw Negash, Klára Valkó, May Y. Ho

المصدر: Pharmacology Research & Perspectives

مصطلحات موضوعية: Ionization, tissue distribution, Phospholipid, Transporter, Plasma protein binding, Original Articles, transporters, Pharmacology, chemistry.chemical_compound, Neurology, chemistry, Pharmacokinetics, In vivo, Lipophilicity, QWBA, Phospholipid Binding, Biophysics, lipophilicity, Distribution (pharmacology), General Pharmacology, Toxicology and Pharmaceutics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cd32780be7b3b16a755fbdb9d63b74Test
https://pubmed.ncbi.nlm.nih.gov/26516585Test

المؤلفون: David A, Brott, Håkan A S, Andersson, Jane, Stewart, Lorna, Ewart, Greg, Christoph, Johannes, Harleman, Duncan, Armstrong, Lewis B, Kinter

المصدر: Toxicology Reports

مصطلحات موضوعية: ADP, adenosine-5′-diphosphate, Carcinogenicity, QWBA, quantitative whole body autoradiography, Dopamine transport inhibitor, LC-MS/MS, liquid chromatography-mass spectrometric, Translational, MOA, mode of action, IC50, inhibitory concentration fifty percent, MTD, maximum tolerated dose, NH, Hill coefficient, E2, estradiol, CHO, Chinese hamster ovary, Article, GLP, good laboratory practice, Prolactin, Uterine tumor, AUC, area under the curve, H&E, hematoxylin and eosin, LLOQ, lower limits of quantification, Cmax, maximal concentration, DAT, dopamine transport, Ki, inhibition concentration, TK, toxicokinetics

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::f3b1920f3bb1125ec941c70d21d9fbacTest
https://pubmed.ncbi.nlm.nih.gov/28962330Test

المؤلفون: P. Vervaeke, S.E. Borgos, N.N. Sanders, F. Combes

المصدر: ADVANCED DRUG DELIVERY REVIEWS
Advanced Drug Delivery Reviews

مصطلحات موضوعية: LNP, WHOLE-BODY AUTORADIOGRAPHY, Pharmaceutical Science, Oxlumo, Distribution, Inclisiran, MALDI-MS, Imaging, Biodistribution, Pfizer, Tissue Distribution, RNA, Small Interfering, bDNA, Leqvio, SIRNA, RNA therapeutic, BioNTech, Regulatory, Onpattro, BLI, Moderna, Patisiran, INTRACELLULAR TRAFFICKING, mRNA Vaccines, Spikevax, MESSENGER-RNA, FLI, Comirnatmy, Lumasiran, COVID-19 Vaccines, mRNA, Lipid nanoparticle, Guidelines, FISH, QWBA, Givlaari, SYSTEMIC DELIVERY, Humans, Veterinary Sciences, RNA, Messenger, FLUORESCENCE, Givosiran, Mass spectrometry, RT-qPCR, COVID-19, MS, IN-SITU HYBRIDIZATION, Pfizer/BioNTech, mRNA vaccine, SMALL-INTERFERING RNA, LIPID NANOPARTICLES, Vaccine

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4323755ba96c48c4b24c779b4d5533daTest