المؤلفون: Verstovsek, Srdan, Talpaz, Moshe, Wadleigh, Martha, Isidori, Alessandro, te Boekhorst, Peter, Savona, Michael R., Bose, Prithviraj, Pozdnyakova, Olga, Mesa, Ruben, El-Galaly, Tarec C., O'Sullivan, Jennifer, Gamel, Katia, Higgins, Brian, Katakam, Sudhakar, Todorov, Boyan, Trunzer, Kerstin, Harrison, Claire N.

المصدر: Verstovsek , S , Talpaz , M , Wadleigh , M , Isidori , A , te Boekhorst , P , Savona , M R , Bose , P , Pozdnyakova , O , Mesa , R , El-Galaly , T C , O'Sullivan , J , Gamel , K , Higgins , B , Katakam , S , Todorov , B , Trunzer , K & Harrison , C N 2024 , ' A randomized, double-blind study of zinpentraxin alfa in patients with myelofibrosis who were previously treated with or ineligible for ruxolitinib: Stage 2 of a phase ....

مصطلحات موضوعية: Aged, Double-Blind Method, Female, Humans, Male, Middle Aged, Nitriles/therapeutic use, Primary Myelofibrosis/drug therapy, Pyrazoles/therapeutic use, Pyrimidines/therapeutic use, Treatment Outcome

العلاقة: https://vbn.aau.dk/da/publications/20641f9e-11e2-497b-b4cd-b9df398b0790Test

الإتاحة: https://doi.org/10.3324/haematol.2023.284410Test
https://vbn.aau.dk/da/publications/20641f9e-11e2-497b-b4cd-b9df398b0790Test
http://www.scopus.com/inward/record.url?scp=85195228374&partnerID=8YFLogxKTest

المساهمون: Jung Yong Hong, Hee Jin Cho, Kum-Hee Yun, Young Han Lee, Seung Hyun Kim, Wooyeol Baek, Sang Kyum Kim, Yurimi Lee, Yoon-La Choi, Minsuk Kwon, Hyo Song Kim, Jeeyun Lee, Kim, Sang Kyum

مصطلحات موضوعية: Humans, Indazoles / therapeutic use, Pyrimidines / pharmacology, Pyrimidines / therapeutic use, Sarcoma* / drug therapy, Sarcoma* / genetics, Sulfonamides / pharmacology, Sulfonamides / therapeutic use, Immune checkpoint inhibitors, Pazopanib, Soft tissue sarcoma, Whole exome sequencings, Whole transcriptome sequencing

العلاقة: CANCER RESEARCH AND TREATMENT; J00453; OAK-2023-00893; OAK-2023-00894; OAK-2023-00895; OAK-2023-00896; OAK-2023-00897; https://ir.ymlib.yonsei.ac.kr/handle/22282913/194163Test; T202302505; CANCER RESEARCH AND TREATMENT, Vol.55(2) : 671-683, 2023-04

الإتاحة: https://doi.org/10.4143/crt.2022.251Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/194163Test

المساهمون: Bo Yi Kim, Changmok Oh, Dongkyu Jeon, Ikhyun Jun, Ho K Lee, Bo-Rahm Kim, Jinhong Park, Kyoung Yul Seo, Kyeong-A Kim, Dami Lim, Seolhee Lee, Jooyun Lee, Hongchul Yoon, Tae-Im Kim, Wan Namkung, Kim, Tae Im

مصطلحات موضوعية: Animals, Conjunctiva / metabolism, Cornea, Cystic Fibrosis Transmembrane Conductance Regulator* / genetics, Cystic Fibrosis Transmembrane Conductance Regulator* / metabolism, Dry Eye Syndromes* / drug therapy, Dry Eye Syndromes* / genetics, Dry Eye Syndromes* / metabolism, Mice, Pyrimidines / metabolism, Pyrimidines / pharmacology, Pyrimidines / therapeutic use, Rabbits, Solubility, Tears / metabolism

العلاقة: JOURNAL OF MEDICINAL CHEMISTRY; J01588; OAK-2022-10755; OAK-2022-10756; OAK-2022-10757; https://ir.ymlib.yonsei.ac.kr/handle/22282913/193524Test; T202300298; JOURNAL OF MEDICINAL CHEMISTRY, Vol.66(1) : 413-434, 2023-01

الإتاحة: https://doi.org/10.1021/acs.jmedchem.2c01382Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/193524Test

المؤلفون: Turner, Richard D, Smith, Jaclyn A, Birring, Surinder S

المصدر: Turner , R D , Smith , J A & Birring , S S 2024 , ' Gefapixant for Chronic Cough ' , JAMA , vol. 331 , no. 6 , pp. 529 . https://doi.org/10.1001/jama.2023.26032Test

مصطلحات موضوعية: Humans, Benzenesulfonamides/therapeutic use, Chronic Cough/drug therapy, Pyrimidines/therapeutic use, Sulfonamides

العلاقة: https://research.manchester.ac.uk/en/publications/a5ec36a5-0bc2-4679-84f7-5cc4aa76c364Test

الإتاحة: https://doi.org/10.1001/jama.2023.26032Test
https://research.manchester.ac.uk/en/publications/a5ec36a5-0bc2-4679-84f7-5cc4aa76c364Test

المساهمون: François Doz, Cornelis M van Tilburg, Birgit Geoerger, Martin Højgaard, Ingrid Øra, Valentina Boni, Michael Capra, Julia Chisholm, Hyun Cheol Chung, Steven G DuBois, Soledad Gallego-Melcon, Nicolas U Gerber, Hiroaki Goto, Juneko E Grilley-Olson, Jordan R Hansford, David S Hong, Antoine Italiano, Hyoung Jin Kang, Karsten Nysom, Anne Thorwarth, Joanna Stefanowicz, Makoto Tahara, David S Ziegler, Igor T Gavrilovic, Ricarda Norenberg, Laura Dima, Esther De La Cuesta, Theodore W Laetsch, Alexander Drilon, Sebastien Perreault, Chung, Hyun Cheol

مصطلحات موضوعية: Adult, Antineoplastic Agents* / therapeutic use, Child, Glioma* / drug therapy, Humans, Neoplasms* / pathology, Oncogene Proteins, Fusion / genetics, Protein Kinase Inhibitors / therapeutic use, Pyrazoles / therapeutic use, Pyrimidines / pharmacology, Pyrimidines / therapeutic use, NTRK gene fusions, TRK fusion, larotrectinib, primary CNS tumors

العلاقة: NEURO-ONCOLOGY; J02346; OAK-2022-06436; https://ir.ymlib.yonsei.ac.kr/handle/22282913/191584Test; T202205416; NEURO-ONCOLOGY, Vol.24(6) : 997-1007, 2022-06

الإتاحة: https://doi.org/10.1093/neuonc/noab274Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/191584Test

المؤلفون: Kröger, Nicolaus, Sbianchi, Giulia, Sirait, Tiarlan, Wolschke, Christine, Beelen, Dietrich, Passweg, Jakob, Robin, Marie, Vrhovac, Radovan, Helbig, Grzegorz, Sockel, Katja, Conneally, Eibhlin, Rubio, Marie Thérèse, Beguin, Yves, Finke, Jürgen, Bernasconi, Paolo, Morozova, Elena, Clausen, Johannes, von dem Borne, Peter, Schaap, Nicolaas, Schroyens, Wilfried, Patriarca, Francesca, di renzo, nicola, Yeğin, Zeynep Arzu, Hayden, Patrick, McLornan, Donal, Yakoub-Agha, Ibrahim

المصدر: http://lobid.org/resources/99370672770606441Test#!, 35(12):3551-3560.

مصطلحات موضوعية: Female [MeSH], Nitriles/therapeutic use [MeSH], Aged [MeSH], Adult [MeSH], Humans [MeSH], Treatment Outcome [MeSH], Pyrazoles/therapeutic use [MeSH], Janus Kinase Inhibitors/therapeutic use [MeSH], Retrospective Studies [MeSH], Middle Aged [MeSH], Translational research, Myeloproliferative disease, Recurrence [MeSH], Survival Rate [MeSH], Primary Myelofibrosis/drug therapy [MeSH], Article, Primary Myelofibrosis/therapy [MeSH], Pyrimidines/therapeutic use [MeSH], Male [MeSH], Graft vs Host Disease/immunology [MeSH], Primary Myelofibrosis/pathology [MeSH], Hematopoietic Stem Cell Transplantation/methods [MeSH], Graft vs Host Disease/pathology [MeSH]

العلاقة: https://repository.publisso.de/resource/frl:6443818Test; https://doi.org/10.1038/s41375-021-01276-4Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632691Test/

الإتاحة: https://doi.org/10.1038/s41375-021-01276-4Test
https://repository.publisso.de/resource/frl:6443818Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632691Test/

المؤلفون: Grunenberg, Alexander, Kaiser, Lisa M., Woelfle, Stephanie, Schmelzle, Birgit, Viardot, Andreas, Möller, Peter, Barth, Thomas F. E., Muche, Rainer, Dreyhaupt, Jens, Raderer, Markus, Kiesewetter, Barbara, Buske, Christian

المصدر: http://lobid.org/resources/99370673697106441Test#!, 21(1):749.

مصطلحات موضوعية: Pyrimidines/pharmacology [MeSH], Antibodies, Monoclonal/therapeutic use [MeSH], Lymphoma, B-Cell, Marginal Zone/drug therapy [MeSH], Study Protocol, Humans [MeSH], Prospective Studies [MeSH], Monoclonal/pharmacology [MeSH], Antineoplastic Combined Chemotherapy Protocols/therapeutic use [MeSH], PI3K inhibitor, Medical and radiation oncology, Pyrimidines/therapeutic use [MeSH], Copanlisib, Antineoplastic Combined Chemotherapy Protocols/pharmacology [MeSH], Marginal zone lymphoma, Quinazolines/pharmacology [MeSH], Phosphoinositide-3 Kinase Inhibitors/therapeutic use [MeSH], Quinazolines/therapeutic use [MeSH], Rituximab

العلاقة: https://repository.publisso.de/resource/frl:6462819Test; https://doi.org/10.1186/s12885-021-08464-6Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243426Test/

الإتاحة: https://doi.org/10.1186/s12885-021-08464-6Test
https://repository.publisso.de/resource/frl:6462819Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8243426Test/

المؤلفون: Christopoulos, Petros, Bozorgmehr, Farastuk, Brückner, Lena, Chung, Inn, Krisam, Johannes, Schneider, Marc A., Stenzinger, Albrecht, Eickhoff, Regina, Mueller, Daniel W., Thomas, Michael

المصدر: http://lobid.org/resources/99370673697106441Test#!, 21(1):743.

مصطلحات موضوعية: Carcinoma, Non-Small-Cell Lung/pathology [MeSH], Pyrimidines/pharmacology [MeSH], Anaplastic lymphoma kinase, Protein Kinase Inhibitors/pharmacology [MeSH], Study Protocol, Humans [MeSH], Prospective Studies [MeSH], Protein Kinase Inhibitors/therapeutic use [MeSH], Brigatinib, Tyrosine kinase inhibitors (TKI), Medical and radiation oncology, Non-small cell lung cancer, Organophosphorus Compounds/pharmacology [MeSH], Pyrimidines/therapeutic use [MeSH], Anaplastic Lymphoma Kinase/drug effects [MeSH], Molecular risk, ALK, Lung Neoplasms/pathology [MeSH], Resistance mutations, Phenotype [MeSH], Non-Small-Cell Lung/drug therapy [MeSH], Lung Neoplasms/drug therapy [MeSH], Organophosphorus Compounds/therapeutic use [MeSH]

العلاقة: https://repository.publisso.de/resource/frl:6462817Test; https://doi.org/10.1186/s12885-021-08460-wTest; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240323Test/

الإتاحة: https://doi.org/10.1186/s12885-021-08460-wTest
https://repository.publisso.de/resource/frl:6462817Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8240323Test/

المساهمون: D Ross Camidge, Hye Ryun Kim, Myung-Ju Ahn, James C H Yang, Ji-Youn Han, Maximilian J Hochmair, Ki Hyeong Lee, Angelo Delmonte, Maria Rosario Garcia Campelo, Dong-Wan Kim, Frank Griesinger, Enriqueta Felip, Raffaele Califano, Alexander I Spira, Scott N Gettinger, Marcello Tiseo, Huamao M Lin, Yuyin Liu, Florin Vranceanu, Huifeng Niu, Pingkuan Zhang, Sanjay Popat, Kim, Hye Ryun

مصطلحات موضوعية: Anaplastic Lymphoma Kinase / genetics, Crizotinib / therapeutic use, Humans, Lung Neoplasms* / drug therapy, Lung Neoplasms* / genetics, Organophosphorus Compounds, Protein Kinase Inhibitors / therapeutic use, Pyrimidines / therapeutic use, ALK tyrosine kinase inhibitor, Anaplastic lymphoma kinase, Brigatinib, Crizotinib, Non–small cell lung cancer

العلاقة: JOURNAL OF THORACIC ONCOLOGY; J01909; OAK-2022-04520; https://ir.ymlib.yonsei.ac.kr/handle/22282913/190628Test; T202126214; JOURNAL OF THORACIC ONCOLOGY, Vol.16(12) : 2091-2108, 2021-12

الإتاحة: https://doi.org/10.1016/j.jtho.2021.07.035Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/190628Test

المساهمون: Hanna Cho, Injae Shin, Hojong Yoon, Eunhye Jeon, Jiwon Lee, Younghoon Kim, SeongShick Ryu, Chiman Song, Nam Hoon Kwon, Youngji Moon, Sunghoon Kim, Nam Doo Kim, Hwan Geun Choi, Taebo Sim, Sim, Taebo

مصطلحات موضوعية: Animals, Antineoplastic Agents / chemical synthesis, Antineoplastic Agents / metabolism, Antineoplastic Agents / pharmacology, Antineoplastic Agents / therapeutic use, Cell Line, Tumor, Drug Screening Assays, Antitumor, Female, Focal Adhesion Kinase 1 / antagonists & inhibitors, Focal Adhesion Kinase 1 / metabolism, Humans, Mice, Inbred BALB C, Nude, Molecular Docking Simulation, Molecular Structure, Neoplasm Metastasis / prevention & control, Neoplasms / drug therapy, Phosphorylation / drug effects, Protein Kinase Inhibitors / chemical synthesis, Protein Kinase Inhibitors / metabolism, Protein Kinase Inhibitors / pharmacology, Protein Kinase Inhibitors / therapeutic use, Pyrimidines / chemical synthesis, Pyrimidines / metabolism, Pyrimidines / pharmacology, Pyrimidines / therapeutic use, Structure-Activity Relationship

العلاقة: JOURNAL OF MEDICINAL CHEMISTRY; J01588; OAK-2021-08342; https://ir.ymlib.yonsei.ac.kr/handle/22282913/187089Test; T202105027; JOURNAL OF MEDICINAL CHEMISTRY, Vol.64(16) : 11934-11957, 2021-07

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c00459Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/187089Test