المساهمون: SeongShick Ryu, Jung-Eun Park, Young Jin Ham, Daniel C Lim, Nicholas P Kwiatkowski, Do-Hee Kim, Debabrata Bhunia, Nam Doo Kim, Michael B Yaffe, Woolim Son, Namkyoung Kim, Tae-Ik Choi, Puspanjali Swain, Cheol-Hee Kim, Jin-Young Lee, Nathanael S Gray, Kyung S Lee, Taebo Sim, Sim, Taebo

مصطلحات موضوعية: Animals, Cell Cycle Proteins / antagonists & inhibitors, Cell Cycle Proteins / chemistry, Cell Cycle Proteins / metabolism, HEK293 Cells, HeLa Cells, Humans, Molecular Docking Simulation, Molecular Structure, Peptides, Cyclic / chemical synthesis, Cyclic / metabolism, Cyclic / pharmacology, Peptidomimetics / chemical synthesis, Peptidomimetics / metabolism, Peptidomimetics / pharmacology, Protein Binding, Protein Domains, Protein Kinase Inhibitors / chemical synthesis, Protein Kinase Inhibitors / metabolism, Protein Kinase Inhibitors / pharmacology, Protein Serine-Threonine Kinases / antagonists & inhibitors, Protein Serine-Threonine Kinases / chemistry, Protein Serine-Threonine Kinases / metabolism, Proto-Oncogene Proteins / antagonists & inhibitors, Proto-Oncogene Proteins / chemistry, Proto-Oncogene Proteins / metabolism, Structure-Activity Relationship, Zebrafish

العلاقة: JOURNAL OF MEDICINAL CHEMISTRY; J01588; OAK-2022-00700; https://ir.ymlib.yonsei.ac.kr/handle/22282913/188018Test; T202200436; JOURNAL OF MEDICINAL CHEMISTRY, Vol.65(3) : 1915-1932, 2022-01

الإتاحة: https://doi.org/10.1021/acs.jmedchem.1c01359Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/188018Test

المؤلفون: Yang, Z., Liang, S.Q., Yang, H., Xu, D., Bruggmann, R., Gao, Y., Deng, H., Berezowska, S., Hall, SRR, Marti, T.M., Kocher, G.J., Zhou, Q., Schmid, R.A., Peng, R.W.

المصدر: Cancer research, vol. 81, no. 11, pp. 3121-3133

مصطلحات موضوعية: Aged, Animals, Apoptosis, Benzamides/pharmacology, CRISPR-Cas Systems, Cell Cycle, Cell Cycle Proteins/antagonists & inhibitors, Cell Cycle Proteins/genetics, Cell Proliferation, Combined Modality Therapy, Gene Amplification, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms/genetics, Lung Neoplasms/metabolism, Lung Neoplasms/pathology, Lung Neoplasms/therapy, Male, Mice, Piperazines/pharmacology, Protein Kinase Inhibitors/pharmacology, Protein Serine-Threonine Kinases/antagonists & inhibitors, Protein Serine-Threonine Kinases/genetics, Proto-Oncogene Proteins/antagonists & inhibitors, Proto-Oncogene Proteins/genetics, Pyrazoles/pharmacology, Receptor, Fibroblast Growth Factor, Type 1/antagonists & inhibitors

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33685992; info:eu-repo/semantics/altIdentifier/eissn/1538-7445; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_6D844130F3DD5; https://serval.unil.ch/notice/serval:BIB_6D844130F3DDTest; urn:issn:0008-5472; https://serval.unil.ch/resource/serval:BIB_6D844130F3DD.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6D844130F3DD5Test

الإتاحة: https://doi.org/10.1158/0008-5472.CAN-20-2276Test
https://serval.unil.ch/notice/serval:BIB_6D844130F3DDTest
https://serval.unil.ch/resource/serval:BIB_6D844130F3DD.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_6D844130F3DD5Test

المؤلفون: Meyskens, Frank L, Jr, Gerner, Eugene W

المصدر: Cancer prevention research (Philadelphia, Pa.). 4(5)

مصطلحات موضوعية: Apoptosis, Biomimetics, Genes, Lethal, Humans, Intracellular Signaling Peptides and Proteins: antagonists & inhibitors, genetics, Lung Neoplasms: genetics, prevention & control, Mitochondrial Proteins: antagonists & inhibitors, genetics, Mutation: genetics, Proto-Oncogene Proteins: antagonists & inhibitors, genetics, TNF-Related Apoptosis-Inducing Ligand: antagonists & inhibitors, genetics, ras Proteins: antagonists & inhibitors, genetics, B Raf kinase inhibitor, eflornithine, imatinib, K ras protein, nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase inhibitor, retinol acetate, retrovirus vector, second mitochondrial activator of caspase, sulindac, tumor necrosis factor related apoptosis inducing ligand, advanced cancer, breast cancer, carcinogenesis, chemoprophylaxis, colorectal cancer, combination chemotherapy, drug targeting, gene mutation, human, lung carcinogenesis, melanoma, metastasis, nonhuman, ovary cancer, practice guideline, priority journal, protein expression, questionnaire, review, viral gene delivery system, Apoptosis, Biomimetics, Genes, Lethal, Humans, Intracellular Signaling Peptides and Proteins, Lung Neoplasms, Mitochondrial Proteins, Mutation, Proto-Oncogene Proteins, ras Proteins, TNF-Related Apoptosis-Inducing Ligand

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/5t1960spTest

المؤلفون: Krause, Daniela S, Van Etten, Richard A

المصدر: The New England journal of medicine. 353(2)

مصطلحات موضوعية: Antibodies, Monoclonal: therapeutic use, Benzamides, Drug Resistance, Neoplasm: genetics, Gene Expression Regulation, Neoplastic, Hematologic Neoplasms: drug therapy, Humans, Mutation, Neoplasms: drug therapy, enzymology, Piperazines: therapeutic use, Protein Kinase Inhibitors: therapeutic use, Protein-Tyrosine Kinases: antagonists & inhibitors, metabolism, Proto-Oncogene Proteins: antagonists & inhibitors, Pyrimidines: therapeutic use, Receptor Protein-Tyrosine Kinases: antagonists & inhibitors, genetics, fms-Like Tyrosine Kinase 3

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/8m95x14jTest

المؤلفون: Hu, Yiguo, Liu, Yuhua, Pelletier, Shawn, Buchdunger, Elisabeth, Warmuth, Markus, Fabbro, Doriano, Hallek, Michael, Van Etten, Richard A, Li, Shaoguang

المصدر: Nature genetics. 36(5)

مصطلحات موضوعية: Animals, Benzamides, Burkitt Lymphoma: enzymology, pathology, Cell Division: drug effects, Drug Therapy, Combination, Enzyme Activation, Enzyme Inhibitors: pharmacology, Fusion Proteins, bcr-abl: metabolism, Humans, Leukemia, Myelogenous, Chronic, BCR-ABL Positive: enzymology, pathology, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, Piperazines: pharmacology, Protein-Tyrosine Kinases: antagonists & inhibitors, physiology, Proto-Oncogene Proteins: antagonists & inhibitors, physiology, Proto-Oncogene Proteins c-hck, Pyrimidines: pharmacology, Pyrroles: pharmacology, src-Family Kinases: antagonists & inhibitors, physiology

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9pq0v9wmTest

المؤلفون: Shun-Qing Liang, Haibin Deng, Ren-Wang Peng, Gregor J. Kocher, Sabina Berezowska, Qinghua Zhou, Zhang Yang, Rémy Bruggmann, Sean Hall, Yanyun Gao, Duo Xu, Thomas M. Marti, Ralph A. Schmid, Haitang Yang

المصدر: Cancer research, vol. 81, no. 11, pp. 3121-3133

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, animal structures, Aged, Animals, Apoptosis, Benzamides/pharmacology, CRISPR-Cas Systems, Cell Cycle, Cell Cycle Proteins/antagonists & inhibitors, Cell Cycle Proteins/genetics, Cell Proliferation, Combined Modality Therapy, Gene Amplification, Gene Expression Regulation, Neoplastic, Humans, Lung Neoplasms/genetics, Lung Neoplasms/metabolism, Lung Neoplasms/pathology, Lung Neoplasms/therapy, Male, Mice, Piperazines/pharmacology, Protein Kinase Inhibitors/pharmacology, Protein Serine-Threonine Kinases/antagonists & inhibitors, Protein Serine-Threonine Kinases/genetics, Proto-Oncogene Proteins/antagonists & inhibitors, Proto-Oncogene Proteins/genetics, Pyrazoles/pharmacology, Receptor, Fibroblast Growth Factor, Type 1/antagonists & inhibitors, Receptor, Fibroblast Growth Factor, Type 1/genetics, Tumor Cells, Cultured, Xenograft Model Antitumor Assays, Cas9, DNA damage, business.industry, Drug resistance, medicine.disease, PLK1, 3. Good health, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, embryonic structures, Cancer cell, Cancer research, medicine, CRISPR, Kinome, biological phenomena, cell phenomena, and immunity, Lung cancer, business

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3974a8b4da8571f690f7572bb8db80fTest
https://doi.org/10.1158/0008-5472.can-20-2276Test

المؤلفون: Cuttano, Roberto, Rudini, Noemi, Bravi, Luca, Corada, Monica, Giampietro, Costanza, Papa, Eleanna, Morini, Marco Francesco, Maddaluno, Luigi, Baeyens, Nicolas, Adams, Ralf H, Jain, Mukesh MK, Owens, Gary GK, Schwartz, Martin A, Lampugnani, Maria Grazia, Dejana, Elisabetta

المصدر: EMBO molecular medicine, 8 (1

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Animals, Bone Morphogenetic Protein 6 -- antagonists & inhibitors -- genetics -- metabolism, Cell Proliferation, Disease Models, Animal, Disease Progression, Endothelial Cells -- cytology -- metabolism, HEK293 Cells, Hemangioma, Cavernous, Central Nervous System -- genetics -- metabolism -- pathology, Humans, Kruppel-Like Transcription Factors -- antagonists & inhibitors -- genetics -- metabolism, Mice, Inbred C57BL, Knockout, Microtubule-Associated Proteins -- antagonists & inhibitors -- genetics -- metabolism, Mitogen-Activated Protein Kinase 7 -- metabolism, Mutation, Proto-Oncogene Proteins -- antagonists & inhibitors -- genetics -- metabolism, RNA Interference, Signal Transduction, Smad1 Protein -- metabolism, Transforming Growth Factor beta -- metabolism, CCM, EndMT, KLF4, TGFβ‐BMP, endothelial cells

وصف الملف: 1 full-text file(s): application/pdf

العلاقة: uri/info:doi/10.15252/emmm.201505433; uri/info:pii/emmm.201505433; uri/info:pmid/26612856; uri/info:pmcid/PMC4718159; https://dipot.ulb.ac.be/dspace/bitstream/2013/260000/4/doi_243627.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/260000Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/260000Test

المساهمون: Rae-Kwon Kim, Yongjoon Suh, Eun-Jung Lim, Ki-Chun Yoo, Ga-Haeng Lee, Yan-Hong Cui, Arang Son, Eunji Hwang, Nizam Uddin, Joo-Mi Yi, Seok-Gu Kang, Su-Jae Lee, Kang, Seok Gu

مصطلحات موضوعية: Antineoplastic Agents/pharmacology, Breast Neoplasms/drug therapy, Breast Neoplasms/pathology, Cell Line, Tumor, Disease Progression, Epithelial-Mesenchymal Transition, Female, Humans, Neoplasm Invasiveness, Proto-Oncogene Proteins/antagonists & inhibitors, Proto-Oncogene Proteins p21(ras), Pyrones/pharmacology, ras Proteins/antagonists & inhibitors, Epithelial�뱈esenchymal transition, Invasion, Malignant progression, Migration, Ras signaling pathway, 慣-Pyrone derivative

العلاقة: CANCER LETTERS; J00448; OAK-2013-00943; https://ir.ymlib.yonsei.ac.kr/handle/22282913/87061Test; http://www.sciencedirect.com/science/article/pii/S0304383513004059Test; T201301848; CANCER LETTERS, Vol.337(1) : 49-57, 2013

الإتاحة: https://doi.org/10.1016/j.canlet.2013.05.023Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/87061Test
http://www.sciencedirect.com/science/article/pii/S0304383513004059Test

المؤلفون: Andrade Da Cunha, Daniel, Igoillo Esteve, Mariana, Gurzov, Esteban Nicolas, Germano, Carla Maria Ramos C.M., Naamane, Najib, Marhfour, Ihsane, Fukaya, Makiko, Vanderwinden, Jean-Marie, Gysemans, Conny, Mathieu, Chantal, Marselli, Lorella, Marchetti, Piero, Harding, Heather HP, Ron, David, Eizirik, Decio, Cnop, Miriam

المصدر: Diabetes (New York, N.Y.), 61 (11

مصطلحات موضوعية: Sciences bio-médicales et agricoles, Aged, Animals, Apoptosis, Apoptosis Regulatory Proteins -- antagonists & inhibitors -- genetics -- metabolism, Cell Line, Cells, Cultured, Endoplasmic Reticulum Stress, Gene Expression Profiling, Humans, Insulin-Secreting Cells -- cytology -- metabolism, Male, Mice, Inbred C57BL, Knockout, Middle Aged, Mitochondria -- metabolism, Palmitic Acid -- adverse effects, Proto-Oncogene Proteins -- antagonists & inhibitors -- genetics -- metabolism, RNA Interference, RNA, Messenger -- metabolism, Small Interfering, Rats

وصف الملف: 1 full-text file(s): application/pdf

العلاقة: uri/info:doi/10.2337/db12-0123; uri/info:pii/db12-0123; uri/info:pmid/22773666; uri/info:pmcid/PMC3478544; https://dipot.ulb.ac.be/dspace/bitstream/2013/222103/1/doi_205730.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/222103Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/222103Test

المؤلفون: Yang, Guo Yuan, Yao, Jianhua S, Huey, Madeleine, Hashimoto, Tomoki, Young, William L

المصدر: Translational Neuroscience

مصطلحات موضوعية: Androstadienes (pharmacology), Cerebrovascular Circulation, Chemotaxis (physiology), Enzyme Inhibitors (pharmacology), Flavonoids (pharmacology), Humans, Mitogen-Activated Protein Kinase 1 (antagonists & inhibitors, metabolism), Mitogen-Activated Protein Kinase 3, Mitogen-Activated Protein Kinases (antagonists & inhibitors, Muscle, Smooth, Vascular (cytology, enzymology), Phosphatidylinositol 3-Kinases (metabolism), Phosphoinositide-3 Kinase Inhibitors, Phosphorylation, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins (antagonists & inhibitors, Proto-Oncogene Proteins c-akt, Vascular Endothelial Growth Factor A (antagonists & inhibitors, physiology), Wortmannin

العلاقة: https://scholar.barrowneuro.org/neurobiology/1688Test; https://doi.org/10.1016/j.neuint.2003.07.002Test

الإتاحة: https://doi.org/10.1016/j.neuint.2003.07.002Test
https://scholar.barrowneuro.org/neurobiology/1688Test