المؤلفون: Noguera-Castells, Aleix

المساهمون: University/Department: Universitat de Barcelona. Departament de Medicina

مرشدي الرسالة: aleixnoguera10@gmail.com, Carbó Carbó, Neus, Mancino, Mario, Cardellach, Francesc

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Oncologia, Oncología, Oncology, Càncer de mama, Cáncer de mama, Breast cancer, Càncer de coll, Cáncer de cuello, Neck cancer, Proteïnes SNARE, Proteínas SNARE, SNARE Proteins, Ciències de la Salut

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/674577Test

المؤلفون: Ros i Torres, Oriol

المساهمون: University/Department: Universitat de Barcelona. Departament de Biologia Cel·lular

مرشدي الرسالة: Soriano García, Eduardo, Cotrufo, Tiziana

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: Exocitosi, Exocitosis, Exocytosis, Guia axonal, Guía axonal, Axon guidance, Desenvolupament neuronal, Desarrollo neuronal, Neuronal development, Proteïnes SNARE, SNARE (protein), Proteínas SNARE, Netrina-1, Netrin-1, Ciències Experimentals i Matemàtiques

وصف الملف: application/pdf

الوصول الحر: http://hdl.handle.net/10803/120452Test

المؤلفون: López Font, Inmaculada Belén

مرشدي الرسالة: Instituto de Neurociencias, Consejo Superior de Investigaciones Científicas, Gutiérrez Pérez, Luis Miguel

مصطلحات موضوعية: medicina, proteínas SNARE, CDU: 61 - Medicina 612 - Fisiología, CDU: 577 - Bioquímica. Biología molecular. Biofísica

الوصول الحر: http://hdl.handle.net/10803/406469Test

المؤلفون: López Font, Inmaculada Belén

مرشدي الرسالة: Instituto de Neurociencias, Consejo Superior de Investigaciones Científicas, Gutiérrez Pérez, Luis Miguel

مصطلحات موضوعية: medicina, proteínas SNARE, CDU: 61 - Medicina 612 - Fisiología, CDU: 577 - Bioquímica. Biología molecular. Biofísica

الوصول الحر: http://hdl.handle.net/11000/1667Test

المؤلفون: Castaño, Diana, Rojas, Mauricio

المصدر: Biomedica; Vol. 30 No. 2 (2010); 283-308 ; Biomédica; Vol. 30 Núm. 2 (2010); 283-308 ; 2590-7379 ; 0120-4157 ; 10.7705/biomedica.v30i2

مصطلحات موضوعية: tuberculosis, Mycobacterium tuberculosis, rab GTP-binding proteins, SNARE proteins, phagosomes, endosomes, proteínas de unión a GTP rab, proteínas SNARE, fagosomas, endosomas

وصف الملف: application/pdf

العلاقة: https://revistabiomedica.org/index.php/biomedica/article/view/192/182Test; https://revistabiomedica.org/index.php/biomedica/article/view/192/373Test; Malik ZA, Denning GM, Kusner DJ. Inhibition of Ca(2+) signaling by Mycobacterium tuberculosis is associated with reduced phagosome-lysosome fusion and increased survival within human macrophages. J Exp Med. 2000;191:287-302. 2. Malik ZA, Thompson CR, Hashimi S, Porter B, Iyer SS, Kusner DJ. Cutting edge: Mycobacterium tuberculosis blocks Ca2+ signaling and phagosome maturation in human macrophages via specific inhibition of sphingosine kinase. J Immunol. 2003;170:2811-5. 3. Roche PA. Intracellular protein traffic in lymphocytes: "how do I get THERE from HERE"? Immunity. 1999;11:391-8. 4. Kroemer G, Galluzzi L, Brenner C. Mitochondrial membrane permeabilization in cell death. Physiol Rev. 2007;87:99-163. 5. Armstrong C, Edwards R, Jan L, Kaback R, Kühlbrandt W, Miller C, et al. Intracellular vesicular traffic. In: Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walter P, editors. Molecular biology of the cell. Fourth edition. New York: Garland Science; 2002. p. 711-66. 6. Le Roy C, Wrana JL. Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling. Nat Rev Mol Cell Biol. 2005;6:112-26. 7. Seaman MN. Membrane traffic in the secretory pathway: Endosome protein sorting: motifs and machinery. Cell Mol Life Sci. 2008;65:2842-58. 8. Grosshans BL, Ortiz D, Novick P. Rabs and their effectors: achieving specificity in membrane traffic. Proc Natl Acad Sci USA. 2006;103:11821-7. 9. Aderem A, Underhill DM. Mechanisms of phagocytosis in macrophages. Annu Rev Immunol. 1999;17:593-623. 10. Haas A. The phagosome: compartment with a license to kill. Traffic. 2007;8:311-30. 11. Vieira OV, Botelho RJ, Grinstein S. Phagosome maturation: aging gracefully. Biochem J. 2002;366:689-704. 12. Scott CC, Botelho RJ, Grinstein S. Phagosome maturation: a few bugs in the system. J Membr Biol. 2003;193:137-52. 13. Underhill DM, Ozinsky A. Phagocytosis of microbes: complexity in action. Annu Rev Immunol. 2002;20:825-52. 14. Clemens DL. Characterization of the Mycobacterium tuberculosis phagosome. Trends Microbiol. 1996;4:113-8. 15. Chua J, Deretic V. Mycobacterium tuberculosis reprograms waves of phosphatidylinositol 3-phosphate on phagosomal organelles. J Biol Chem. 2004;279:36982-92. 16. Kusner DJ. Mechanisms of mycobacterial persistence in tuberculosis. Clin Immunol. 2005;114:239-47. 17. Deretic V, Singh S, Master S, Harris J, Roberts E, Kyei G, et al. Mycobacterium tuberculosis inhibition of phagolysosome biogenesis and autophagy as a host defense mechanism. Cell Microbiol. 2006;8:719-27. 18. Spiegel S, Kolesnick R. Sphingosine 1-phosphate as a therapeutic agent. Leukemia. 2002;16:1596-602. 19. Yadav M, Clark L, Schorey JS. Macrophage's proinflammatory response to a mycobacterial infection is dependent on sphingosine kinase-mediated activation of phosphatidylinositol phospholipase C, protein kinase C, ERK1/2, and phosphatidylinositol 3-kinase. J Immunol. 2006;176:5494-503. 20. Colombo MI, Beron W, Stahl PD. Calmodulin regulates endosome fusion. J Biol Chem. 1997;272:7707-12. 21. Lindmo K, Stenmark H. Regulation of membrane traffic by phosphoinositide 3-kinases. J Cell Sci. 2006;119:605-14. 22. Deretic V, Fratti RA. Mycobacterium tuberculosis phagosome. Mol Microbiol. 1999;31:1603-9. 23. Chua J, Vergne I, Master S, Deretic V. A tale of two lipids: Mycobacterium tuberculosis phagosome maturation arrest. Curr Opin Microbiol. 2004;7:71-7. 24. Garin J, Diez R, Kieffer S, Dermine JF, Duclos S, Gagnon E, et al. The phagosome proteome: insight into phagosome functions. J Cell Biol. 2001;152:165-80. 25. Gagnon E, Duclos S, Rondeau C, Chevet E, Cameron PH, Steele-Mortimer O, et al. Endoplasmic reticulum-mediated phagocytosis is a mechanism of entry into macrophages. Cell. 2002;110:119-31. 26. Vieira OV, Bucci C, Harrison RE, Trimble WS, Lanzetti L, Gruenberg J, et al. Modulation of Rab5 and Rab7 recruitment to phagosomes by phosphatidylinositol 3-kinase. Mol Cell Biol. 2003;23:2501-14. 27. Stow JL, Manderson AP, Murray RZ. SNAREing immunity: the role of SNAREs in the immune system. Nat Rev Immunol. 2006;6:919-29. 28. Zhao C, Slevin JT, Whiteheart SW. Cellular functions of NSF: not just SNAPs and SNAREs. FEBS Lett. 2007;581:2140-9. 29. Hong W. Cytotoxic T lymphocyte exocytosis: bring on the SNAREs! Trends Cell Biol. 2005;15:644-50. 30. Leabu M. Membrane fusion in cells: molecular machinery and mechanisms. J Cell Mol Med. 2006;10:423-7. 31. Pereira-Leal JB, Seabra MC. Evolution of the Rab family of small GTP-binding proteins. J Mol Biol. 2001;313:889-901. 32. Zerial M, McBride H. Rab proteins as membrane organizers. Nat Rev Mol Cell Biol. 2001;2:107-17. 33. Stenmark H, Olkkonen VM. The Rab GTPase family. Genome Biol. 2001;2:3007. 34. Seabra MC, Wasmeier C. Controlling the location and activation of Rab GTPases. Curr Opin Cell Biol. 2004;16:451-7. 35. Heo WD, Inoue T, Park WS, Kim ML, Park BO, Wandless TJ, et al. PI(3,4,5)P3 and PI(4,5)P2 lipids target proteins with polybasic clusters to the plasma membrane. Science. 2006;314:1458-61. 36. Yeung T, Terebiznik M, Yu L, Silvius J, Abidi WM, Philips M, et al. Receptor activation alters inner surface potential during phagocytosis. Science. 2006;313:347-51. 37. Segev N. Ypt and Rab GTPases: insight into functions through novel interactions. Curr Opin Cell Biol. 2001;13: 500-11. 38. Echard A, Jollivet F, Martinez O, Lacapere JJ, Rousselet A, Janoueix-Lerosey I, et al. Interaction of a Golgi-associated kinesin-like protein with Rab6. Science. 1998;279:580-5. 39. Wu X, Rao K, Bowers MB, Copeland NG, Jenkins NA, Hammer JA 3rd. Rab27a enables myosin Va-dependent melanosome capture by recruiting the myosin to the organelle. J Cell Sci. 2001;114:1091-100. 40. Pan H, Yan BS, Rojas M, Shebzukhov YV, Zhou H, Kobzik L, et al. Ipr1 gene mediates innate immunity to tuberculosis. Nature. 2005;434:767-72. 41. Gil DP, Leon LG, Correa LI, Maya JR, Paris SC, Garcia LF, et al. Differential induction of apoptosis and necrosis in monocytes from patients with tuberculosis and healthy control subjects. J Infect Dis. 2004;189:2120-8. 42. Arcila ML, Sánchez MD, Ortiz B, Barrera LF, García LF, Rojas M. Activation of apoptosis, but not necrosis, during Mycobacterium tuberculosis infection correlated with decreased bacterial growth: role of TNF-alpha, IL-10, caspases and phospholipase A2. Cell Immunol. 2007;249:80-93. 43. Vergne I, Chua J, Singh SB, Deretic V. Cell biology of Mycobacterium tuberculosis phagosome. Annu Rev Cell Dev Biol. 2004;20:367-94. 44. Stamm LM, Morisaki JH, Gao LY, Jeng RL, McDonald KL, Roth R, et al. Mycobacterium marinum escapes from phagosomes and is propelled by actin-based motility. J Exp Med. 2003;198:1361-8. 45. van der Wel N, Hava D, Houben D, Fluitsma D, van Zon M, Pierson J, et al. M. tuberculosis and M. leprae translocate from the phagolysosome to the cytosol in myeloid cells. Cell. 2007;129:1287-98. 46. Brumell JH, Scidmore MA. Manipulation of Rab GTPase function by intracellular bacterial pathogens. Microbiol Mol Biol Rev. 2007;71:636-52. 47. Bucci C, Parton RG, Mather IH, Stunnenberg H, Simons K, Hoflack B, et al. The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway. Cell. 1992;70:715-28. 48. Bucci C, Lutcke A, Steele-Mortimer O, Olkkonen VM, Dupree P, Chiariello M, et al. Co-operative regulation of endocytosis by three Rab5 isoforms. FEBS Lett. 1995;366:65-71. 49. Desjardins M, Huber LA, Parton RG, Griffiths G. Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus. J Cell Biol. 1994;124:677-88. 50. Stenmark H, Parton RG, Steele-Mortimer O, Lutcke A, Gruenberg J, Zerial M. Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. Embo J. 1994;13:1287-96. 51. Gorvel JP, Chavrier P, Zerial M, Gruenberg J. Rab5 controls early endosome fusion in vitro. Cell. 1991;64:915-25. 52. Barbieri MA, Li G, Colombo MI, Stahl PD. Rab5, an early acting endosomal GTPase, supports in vitro endosome fusion without GTP hydrolysis. J Biol Chem. 1994;269:18720-2. 53. Duclos S, Corsini R, Desjardins M. Remodeling of endosomes during lysosome biogenesis involves ‘kiss and run' fusion events regulated by Rab5. J Cell Sci. 2003;116:907-18. 54. Henry RM, Hoppe AD, Joshi N, Swanson JA. The uniformity of phagosome maturation in macrophages. J Cell Biol. 2004;164:185-94. 55. Kitano M, Nakaya M, Nakamura T, Nagata S, Matsuda M. Imaging of Rab5 activity identifies essential regulators for phagosome maturation. Nature. 2008;453:241-5. 56. Duclos S, Diez R, Garin J, Papadopoulou B, Descoteaux A, Stenmark H, et al. Rab5 regulates the kiss and run fusion between phagosomes and endosomes and the acquisition of phagosome leishmanicidal properties in RAW 264.7 macrophages. J Cell Sci. 2000;113:3531-41. 57. Mukherjee K, Siddiqi SA, Hashim S, Raje M, Basu SK, Mukhopadhyay A. Live Salmonella recruits N-ethylmaleimide-sensitive fusion protein on phagosomal membrane and promotes fusion with early endosome. J Cell Biol. 2000;148:741-53. 58. Prada-Delgado A, Carrasco-Marín E, Pena-Macarro C, Del Cerro-Vadillo E, Fresno-Escudero M, Leyva-Cobian F, et al. Inhibition of Rab5a exchange activity is a key step for Listeria monocytogenes survival. Traffic. 2005;6:252-65. 59. Perskvist N, Roberg K, Kulyte A, Stendahl O. Rab5a GTPase regulates fusion between pathogen-containing phagosomes and cytoplasmic organelles in human neutrophils. J Cell Sci. 2002;115:1321-30. 60. Hart PD, Armstrong JA, Brown CA, Draper P. Ultrastructural study of the behavior of macrophages toward parasitic mycobacteria. Infect Immun. 1972;5:803-7. 61. Hart PD, Armstrong JA. Strain virulence and the lysosomal response in macrophages infected with Mycobacterium tuberculosis. Infect Immun. 1974;10:742-6. 62. Via LE, Deretic D, Ulmer RJ, Hibler NS, Huber LA, Deretic V. Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by Rab5 and Rab7. J Biol Chem. 1997;272:13326-31. 63. Clemens DL, Lee BY, Horwitz MA. Deviant expression of Rab5 on phagosomes containing the intracellular pathogens Mycobacterium tuberculosis and Legionella pneumophila is associated with altered phagosomal fate. Infect Immun. 2000;68:2671-84. 64. Fratti RA, Backer JM, Gruenberg J, Corvera S, Deretic V. Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest. J Cell Biol. 2001;154:631-44. 65. Shimada K, Takimoto H, Yano I, Kumazawa Y. Involvement of mannose receptor in glycopeptidolipid-mediated inhibition of phagosome-lysosome fusion. Microbiol Immunol. 2006;50:243-51. 66. Fratti RA, Chua J, Vergne I, Deretic V. Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. Proc Natl Acad Sci USA. 2003;100:5437-42. 67. Fratti RA, Chua J, Deretic V. Cellubrevin alterations and Mycobacterium tuberculosis phagosome maturation arrest. J Biol Chem. 2002;277:17320-6. 68. Kelley VA, Schorey JS. Mycobacterium's arrest of phagosome maturation in macrophages requires Rab5 activity and accessibility to iron. Mol Biol Cell. 2003;14:3366-77. 69. Fuchs TA, Abed U, Goosmann C, Hurwitz R, Schulze I, Wahn V, et al. Novel cell death program leads to neutrophil extracellular traps. J Cell Biol. 2007;176:231-41. 70. Kelley VA, Schorey JS. Modulation of cellular phosphatidylinositol 3-phosphate levels in primary macrophages affects heat-killed but not viable Myco-bacterium avium's transport through the phagosome maturation process. Cell Microbiol. 2004;6:973-85. 71. Vergne I, Chua J, Lee HH, Lucas M, Belisle J, Deretic V. Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis. Proc Natl Acad Sci USA. 2005;102:4033-8. 72. Kang PB, Azad AK, Torrelles JB, Kaufman TM, Beharka A, Tibesar E, et al. The human macrophage mannose receptor directs Mycobacterium tuberculosis lipoarabinomannan-mediated phagosome biogenesis. J Exp Med. 2005;202:987-99. 73. Chavrier P, Parton RG, Hauri HP, Simons K, Zerial M. Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments. Cell. 1990;62:317-29. 74. Bottger G, Nagelkerken B, van der Sluijs P. Rab4 and Rab7 define distinct nonoverlapping endosomal compartments. J Biol Chem. 1996;271:29191-7. 75. Vitelli R, Santillo M, Lattero D, Chiariello M, Bifulco M, Bruni CB, et al. Role of the small GTPase Rab7 in the late endocytic pathway. J Biol Chem. 1997;272:4391-7. 76. Meresse S, Gorvel JP, Chavrier P. The Rab7 GTPase resides on a vesicular compartment connected to lysosomes. J Cell Sci. 1995;108:3349-58. 77. Bucci C, Thomsen P, Nicoziani P, McCarthy J, van Deurs B. Rab7: a key to lysosome biogenesis. Mol Biol Cell. 2000;11:467-80. 78. Feng Y, Press B, Wandinger-Ness A. Rab 7: an important regulator of late endocytic membrane traffic. J Cell Biol. 1995;131:1435-52. 79. Press B, Feng Y, Hoflack B, Wandinger-Ness A. Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment. J Cell Biol. 1998;140:1075-89. 80. Cantalupo G, Alifano P, Roberti V, Bruni CB, Bucci C. Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes. Embo J. 2001;20:683-93. 81. Jordens I, Fernández-Borja M, Marsman M, Dusseljee S, Janssen L, Calafat J, et al. The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors. Curr Biol. 2001;11:1680-5. 82. Harrison RE, Bucci C, Vieira OV, Schroer TA, Grinstein S. Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP. Mol Cell Biol. 2003;23:6494-506. 83. Saito F, Kuwata H, Oiki E, Koike M, Uchiyama Y, Honda K, et al. Inefficient phagosome maturation in infant macrophages. Biochem Biophys Res Commun. 2008;375:113-8. 84. Scianimanico S, Desrosiers M, Dermine JF, Meresse S, Descoteaux A, Desjardins M. Impaired recruitment of the small GTPase Rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes. Cell Microbiol. 1999;1:19-32. 85. Clemens DL, Lee BY, Horwitz MA. Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7. Infect Immun. 2000;68:5154-66. 86. Hmama Z, Sendide K, Talal A, Garcia R, Dobos K, Reiner NE. Quantitative analysis of phagolysosome fusion in intact cells: inhibition by mycobacterial lipoarabinomannan and rescue by an 1alpha,25-dihydroxyvitamin D3-phosphoinositide 3-kinase pathway. J Cell Sci. 2004; 117:2131-40. 87. Sun J, Deghmane AE, Soualhine H, Hong T, Bucci C, Solodkin A, et al. Mycobacterium bovis BCG disrupts the interaction of Rab7 with RILP contributing to inhibition of phagosome maturation. J Leukoc Biol. 2007;82:1437-45. 88. Ullrich O, Reinsch S, Urbe S, Zerial M, Parton RG. Rab11 regulates recycling through the pericentriolar recycling endosome. J Cell Biol. 1996;135:913-24. 89. Ren M, Xu G, Zeng J, De Lemos-Chiarandini C, Adesnik M, Sabatini DD. Hydrolysis of GTP on Rab11 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes. Proc Natl Acad Sci USA. 1998;95:6187-92. 90. Cox D, Lee DJ, Dale BM, Calafat J, Greenberg S. A Rab11-containing rapidly recycling compartment in macrophages that promotes phagocytosis. Proc Natl Acad Sci USA. 2000;97:680-5. 91. Tailleux L, Neyrolles O, Honore-Bouakline S, Perret E, Sánchez F, Abastado JP, et al. Constrained intracellular survival of Mycobacterium tuberculosis in human dendritic cells. J Immunol. 2003;170:1939-48. 92. Fratti RA, Vergne I, Chua J, Skidmore J, Deretic V. Regulators of membrane trafficking and Mycobacterium tuberculosis phagosome maturation block. Electrophoresis. 2000;21:3378-85. 93. Roberts EA, Chua J, Kyei GB, Deretic V. Higher order Rab programming in phagolysosome biogenesis. J Cell Biol. 2006;174:923-9. 94. Junutula JR, De Maziere AM, Peden AA, Ervin KE, Advani RJ, van Dijk SM, et al. Rab14 is involved in membrane trafficking between the Golgi complex and endosomes. Mol Biol Cell. 2004;15:2218-29. 95. Kyei GB, Vergne I, Chua J, Roberts E, Harris J, Junutula JR, et al. Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest. Embo J. 2006;25:5250-9. 96. Lombardi D, Soldati T, Riederer MA, Goda Y, Zerial M, Pfeffer SR. Rab9 functions in transport between late endosomes and the trans Golgi network. Embo J. 1993;12:677-82. 97. Riederer MA, Soldati T, Shapiro AD, Lin J, Pfeffer SR. Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi network. J Cell Biol. 1994;125:573-82. 98. Brunt LM, Portnoy DA, Unanue ER. Presentation of Listeria monocytogenes to CD8+ T cells requires secretion of hemolysin and intracellular bacterial growth. J Immunol. 1990;145:3540-6. 99. Rojas M, García LF, Nigou J, Puzo G, Olivier M. Mannosylated lipoarabinomannan antagonizes Mycobacterium tuberculosis-induced macrophage apoptosis by altering Ca+2-dependent cell signaling. J Infect Dis. 2000;182:240-51. 100. Steinberg BE, Grinstein S. Pathogen destruction versus intracellular survival: the role of lipids as phagosomal fate determinants. J Clin Invest. 2008;118:2002-11. 101. Huynh KK, Gershenzon E, Grinstein S. Cholesterol accumulation by macrophages impairs phagosome maturation. J Biol Chem. 2008;283:35745-55. 102. Jacobsen M, Repsilber D, Gutschmidt A, Neher A, Feldmann K, Mollenkopf HJ, et al. Ras-associated small GTPase 33A, a novel T cell factor, is down-regulated in patients with tuberculosis. J Infect Dis. 2005;192:1211-8.; https://revistabiomedica.org/index.php/biomedica/article/view/192Test

الإتاحة: https://doi.org/10.7705/biomedica.v30i2Test
https://revistabiomedica.org/index.php/biomedica/article/view/192Test

المؤلفون: Cunha, Daniel Andrade da

مرشدي الرسالة: UNIVERSIDADE ESTADUAL DE CAMPINAS, Boschiero, Antonio Carlos, 1943, Boschero, Antonio Carlos, 1943, Saad, Mario José Abdalla, Rocha, Eduardo Melani, Velloso, Licio Augusto, Carvalho, Carla Roberta de Oliveira

المصدر: Repositório Institucional da UnicampUniversidade Estadual de CampinasUNICAMP.

مصطلحات موضوعية: Proteinas SNARE, Prolactina, Ilhotas pancreáticas, MAP2, Kinesina, SNARE proteins, Islets of Langerhans, Prolactin, Kinesin

وصف الملف: 43f. : il.; application/pdf

الإتاحة: http://repositorio.unicamp.br/jspui/handle/REPOSIP/313930Test

المؤلفون: Daniel Andrade da Cunha

المساهمون: Boschero, Antonio Carlos, 1943, Boschiero, Antonio Carlos, 1943, Saad, Mario José Abdalla, Rocha, Eduardo Melani, Velloso, Licio Augusto, Carvalho, Carla Roberta de Oliveira, Universidade Estadual de Campinas. Instituto de Biologia, Programa de Pós-Graduação em Biologia Funcional e Molecular, UNIVERSIDADE ESTADUAL DE CAMPINAS

المصدر: Biblioteca Digital de Teses e Dissertações da Universidade Estadual de Campinas (UNICAMP)
Universidade Estadual de Campinas (UNICAMP)
instacron:UNICAMP

مصطلحات موضوعية: Proteinas SNARE, Islets of Langerhans, SNARE proteins, Ilhotas pancreáticas, Kinesina, Prolactina, MAP2, Kinesin, Prolactin

وصف الملف: application/pdf; 43f. : il.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc59b0d39f084901b92528a49436fb7dTest

المؤلفون: López Font, Inmaculada Belén

المساهمون: Gutiérrez Pérez, Luis Miguel, Instituto de Neurociencias

مصطلحات موضوعية: medicina, proteínas SNARE, CDU: 61 - Medicina 612 - Fisiología, CDU: 577 - Bioquímica. Biología molecular. Biofísica

وصف الملف: application/pdf

العلاقة: 347; http://hdl.handle.net/11000/1667Test

الإتاحة: http://hdl.handle.net/11000/1667Test

المؤلفون: Oliveira, Daniele Correia de Sales Marques de UNIFESP

المساهمون: Carvalho, Carolina Prado de França UNIFESP, Universidade Federal de São Paulo (UNIFESP)

مصطلحات موضوعية: High Fat Diet, Metabolic Programming, Type 2 Diabetes Mellitus, Endocrine Pancreas, SNARE Proteins, Dieta Hiperlipídica, Programação Metabólica, Diabetes Mellitus Tipo 2, Pâncreas Endócrino, Proteínas SNARE

وصف الملف: 77 p.

العلاقة: https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7889292Test; OLIVEIRA, Daniele Correia de Sales Marques de. Estudo da expressão de proteínas SNARE no pâncreas endócrino de animais da prole de fêmeas de camundongo alimentadas com dieta hiperlipídica durante a gestação e lactação. 2019. 77 f. Dissertação (Mestrado Interdisciplinar em Ciências da Saúde) - Instituto de Saúde e Sociedade, Universidade Federal de São Paulo, Santos, 2019.; https://repositorio.unifesp.br/handle/11600/59548Test

الإتاحة: https://repositorio.unifesp.br/handle/11600/59548Test
https://sucupira.capes.gov.br/sucupira/public/consultas/coleta/trabalhoConclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=7889292Test