المؤلفون: Shawn C. C. Hsueh, Mark Nijland, Adekunle Aina, Steven S. Plotkin

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, vaccine immunogen design, two cyclized constructs, two cyclic constructs, oligomeric structural mimic, multiple cyclic peptides, molecular dynamics simulations, lowercase letters indicate, free energy required, free energy calculations, cyclo -( vksekldfkdrvqskiyvg, cyclo -( vksekldfkdrvqskifyn, conjugated peptide constructs, protein misfolding diseases, previous computational work, conformational properties similar, vitro tau oligomers, effectively design immunogens, disease effective scaffolding, cyclization scaffolding method, cyclization scaffolding

العلاقة: https://figshare.com/articles/journal_contribution/Cyclization_Scaffolding_for_Improved_Vaccine_Immunogen_Stability_Application_to_Tau_Protein_in_Alzheimer_s_Disease/25326219Test

الإتاحة: https://doi.org/10.1021/acs.jcim.3c01556.s001Test
https://figshare.com/articles/journal_contribution/Cyclization_Scaffolding_for_Improved_Vaccine_Immunogen_Stability_Application_to_Tau_Protein_in_Alzheimer_s_Disease/25326219Test

المؤلفون: Remarh Bsoul, Eva Løbner Lund, Kimberley Burns, Mary Andrews, Neil McKenzie, Alison Green, Aušrinė Areškevičiūtė

المصدر: International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6098

مصطلحات موضوعية: Creutzfeldt–Jakob disease—CJD, improved real-time quaking-induced conversion—IQ, RT-QuIC, cerebrospinal fluid—CSF, prions, prion disease, neurodegenerative protein misfolding diseases, early diagnostics, recombinant PrP production and storage

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Neurobiology; https://dx.doi.org/10.3390/ijms24076098Test

الإتاحة: https://doi.org/10.3390/ijms24076098Test

المؤلفون: Bsoul, Remarh, Lund, Eva Løbner, Burns, Kimberley, Andrews, Mary, McKenzie, Neil, Green, Alison, Areškevičiūtė, Aušrinė

المصدر: Bsoul , R , Lund , E L , Burns , K , Andrews , M , McKenzie , N , Green , A & Areškevičiūtė , A 2023 , ' Improved Real-Time Quaking Induced Conversion for Early Diagnostics of Creutzfeldt–Jakob Disease in Denmark ' , International Journal of Molecular Sciences , vol. 24 , no. 7 , 6098 . https://doi.org/10.3390/ijms24076098Test

مصطلحات موضوعية: cerebrospinal fluid—CSF, Creutzfeldt–Jakob disease—CJD, early diagnostics, improved real-time quaking-induced conversion—IQ, neurodegenerative protein misfolding diseases, prion disease, prions, recombinant PrP production and storage, RT-QuIC

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.3390/ijms24076098Test
https://curis.ku.dk/portal/da/publications/improved-realtime-quaking-induced-conversion-for-early-diagnostics-of-creutzfeldtjakob-disease-in-denmarkTest(0c87bc3c-e17d-4fdc-9294-bc88f8f03c56).html
https://curis.ku.dk/ws/files/369362725/mproved_Real_Time.pdfTest
http://www.scopus.com/inward/record.url?scp=85152324498&partnerID=8YFLogxKTest

المؤلفون: Irina Dudanova

المصدر: Frontiers in Molecular Neuroscience, Vol 15 (2022)

مصطلحات موضوعية: proteostasis, protein quality control, protein folding, neuron, biosensor, protein misfolding diseases, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fnmol.2022.829365/fullTest; https://doaj.org/toc/1662-5099Test

الوصول الحر: https://doaj.org/article/3a6eb4222d46464087813cf321c8f85aTest

المؤلفون: Sushma Subedi, Santanu Sasidharan, Niharika Nag, Prakash Saudagar, Timir Tripathi

المصدر: Molecules; Volume 27; Issue 6; Pages: 1776

مصطلحات موضوعية: amyloid proteins, aggregation, cross-seeding, protein misfolding diseases, dual inhibition, fibrillation

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Physical Chemistry; https://dx.doi.org/10.3390/molecules27061776Test

الإتاحة: https://doi.org/10.3390/molecules27061776Test

المؤلفون: Pauline Elisabeth Kolkwitz, Jeannine Mohrlüder, Dieter Willbold

المصدر: Biomolecules; Volume 12; Issue 2; Pages: 157

مصطلحات موضوعية: polyglutamine diseases, protein misfolding diseases, phage display, all-D-peptide therapeutics, protein aggregation

جغرافية الموضوع: agris

وصف الملف: application/pdf

العلاقة: Molecular Medicine; https://dx.doi.org/10.3390/biom12020157Test

الإتاحة: https://doi.org/10.3390/biom12020157Test

المؤلفون: Albuquerque, Hélio, Silva, Raquel Nunes da, Pereira, Marisa, Maia, André, Guieu, Samuel, Soares, Ana Raquel, Santos, Clementina M.M., Vieira, Sandra I., Silva, Artur

مصطلحات موضوعية: Steroid−quinoline hybrids, Protein aggregation, Amyloid-β (Aβ) peptide, Protein misfolding diseases

العلاقة: info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UIDB%2F50006%2F2020/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FBIM%2F04501%2F2019/PT; info:eu-repo/grantAgreement/FCT/6817 - DCRRNI ID/UID%2FCTM%2F50011%2F2019/PT; BPD/UI98/4861/2017; BPD/UI98/6327/2018; info:eu-repo/grantAgreement/FCT/POR_CENTRO/SFRH%2FBD%2F135655%2F2018/PT; Albuquerque, Hélio M.T.; Silva, Raquel Nunes da; Pereira, Marisa; Maia, André; Guieu, Samuel; Soares, Ana Raquel; Santos, Clementina M. M.; Vieira, Sandra I.; Silva, Artur (2022). Steroid–quinoline hybrids for disruption and reversion of protein aggregation processes. ACS Medicinal Chemistry Letters. ISSN 1948-5875. p. 1-6; http://hdl.handle.net/10198/25132Test

الإتاحة: https://doi.org/10.1021/acsmedchemlett.1c00604Test
http://hdl.handle.net/10198/25132Test

المؤلفون: Lane, Fiona Mary

المساهمون: Gill, Andrew, Hardingham, Giles, Manson, Jean

مصطلحات موضوعية: 616.8, protein misfolding diseases, Alzheimer’s disease, prion diseases, protein toxicity

الوصول الحر: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.702256Test

المؤلفون: Ryan Limbocker, Roxine Staats, Sean Chia, Francesco S. Ruggeri, Benedetta Mannini, Catherine K. Xu, Michele Perni, Roberta Cascella, Alessandra Bigi, Liam R. Sasser, Natalie R. Block, Aidan K. Wright, Ryan P. Kreiser, Edward T. Custy, Georg Meisl, Silvia Errico, Johnny Habchi, Patrick Flagmeier, Tadas Kartanas, Jared E. Hollows, Lam T. Nguyen, Kathleen LeForte, Denise Barbut, Janet R. Kumita, Cristina Cecchi, Michael Zasloff, Tuomas P. J. Knowles, Christopher M. Dobson, Fabrizio Chiti, Michele Vendruscolo

المصدر: Frontiers in Neuroscience, Vol 15 (2021)

مصطلحات موضوعية: protein misfolding diseases, amyloid-β, Alzheimer’s disease, α-synuclein, Parkinson’s disease, oligomers, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

العلاقة: https://www.frontiersin.org/articles/10.3389/fnins.2021.680026/fullTest; https://doaj.org/toc/1662-453XTest

الوصول الحر: https://doaj.org/article/dd03b8d056964d40bab6c08d74df6acbTest

المؤلفون: Limbocker, Ryan, Staats, Roxine, Chia, Sean, Ruggeri, Francesco S., Mannini, Benedetta, Xu, Catherine K., Perni, Michele, Cascella, Roberta, Bigi, Alessandra, Sasser, Liam R., Block, Natalie R., Wright, Aidan K., Kreiser, Ryan P., Custy, Edward T., Meisl, Georg, Errico, Silvia, Habchi, Johnny, Flagmeier, Patrick, Kartanas, Tadas, Hollows, Jared E., Nguyen, Lam T., LeForte, Kathleen, Barbut, Denise, Kumita, Janet R., Cecchi, Cristina, Zasloff, Michael, Knowles, Tuomas P.J., Dobson, Christopher M., Chiti, Fabrizio, Vendruscolo, Michele

المصدر: Frontiers in Neuroscience 15 (2021) ; ISSN: 1662-4548

مصطلحات موضوعية: Alzheimer’s disease, Parkinson’s disease, aminosterols, amyloid-β, oligomers, protein misfolding diseases, small molecule drug discovery, α-synuclein

وصف الملف: application/pdf

العلاقة: https://edepot.wur.nl/550520Test; https://research.wur.nl/en/publications/squalamine-and-its-derivatives-modulate-the-aggregation-of-amyloiTest

الإتاحة: https://doi.org/10.3389/fnins.2021.680026Test
https://research.wur.nl/en/publications/squalamine-and-its-derivatives-modulate-the-aggregation-of-amyloiTest