المؤلفون: Stanke-Labesque, Francoise, Concordet, Didier, Djerada, Zoubir, Bouchet, Stephane, Solas, Caroline, Meriglier, Etienne, Bonnet, Fabrice, Mourvillier, Bruno, Ruiz, Stephanie, Martin-Blondel, Guillaume, Epaulard, Olivier, Schwebel, Carole, Gautier-Veyret, Elodie, Gandia, Peggy

المساهمون: Université Grenoble Alpes - UFR Pharmacie (UGA UFRP), Université Grenoble Alpes (UGA), Centre Hospitalier Universitaire CHU Grenoble (CHUGA), Innovations Thérapeutiques et Résistances (InTheRes), Ecole Nationale Vétérinaire de Toulouse (ENVT), Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National Polytechnique (Toulouse) (Toulouse INP), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital universitaire Robert Debré Reims (CHU Reims), SFR CAP Santé (Champagne-Ardenne Picardie Santé), Université de Reims Champagne-Ardenne (URCA), Hémostase et Remodelage Vasculaire Post-Ischémie (HERVI - EA 3801), Bordeaux population health (BPH), Université de Bordeaux (UB)-Institut de Santé Publique, d'Épidémiologie et de Développement (ISPED)-Institut National de la Santé et de la Recherche Médicale (INSERM), Département Hospitalo-Universitaire de Pharmacologie de Bordeaux, CHU de Bordeaux Pellegrin Bordeaux -Université Victor Segalen - Bordeaux 2, Pharmacocinétique Toxicocinétique - Hôpital de la Timone - APHM, Assistance Publique - Hôpitaux de Marseille (APHM)-Hôpital de la Timone CHU - APHM (TIMONE), Service de médecine interne et maladies infectieuses Bordeaux, CHU Bordeaux-Groupe hospitalier Saint-André, Laboratoire de Virologie Médicale et Moléculaire - EA 4684 (CardioVir), Université de Reims Champagne-Ardenne (URCA)-SFR CAP Santé (Champagne-Ardenne Picardie Santé), Université de Reims Champagne-Ardenne (URCA)-Université de Reims Champagne-Ardenne (URCA)-Hôpital universitaire Robert Debré Reims (CHU Reims), Pôle Anesthésie Réanimation CHU de Toulouse, Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Service Maladies infectieuses et tropicales CHU Toulouse, Pôle Inflammation, infection, immunologie et loco-moteur CHU Toulouse (Pôle I3LM Toulouse), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), Radiopharmaceutiques biocliniques (LRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Laboratoire Pharmacocinétique et de Toxicologie CHU Toulouse, Institut Fédératif de Biologie (IFB), Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Pôle Biologie CHU Toulouse

المصدر: ISSN: 0009-9236.

مصطلحات موضوعية: MESH: Aged, MESH: Albumins / metabolism, MESH: Lopinavir / therapeutic use, MESH: Male, MESH: Middle Aged, MESH: Plasma / physiology, MESH: Protein Binding / physiology, MESH: Retrospective Studies, MESH: SARS-CoV-2, MESH: Viral Load, MESH: Antiviral Agents / pharmacokinetics, MESH: Antiviral Agents / therapeutic use, MESH: C-Reactive Protein / metabolism, MESH: COVID-19 / drug therapy, MESH: Female, MESH: Glycoproteins / metabolism, MESH: Humans, MESH: Lopinavir / pharmacokinetics, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, [SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseases

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/33547636; hal-03191652; https://hal.science/hal-03191652Test; https://hal.science/hal-03191652/documentTest; https://hal.science/hal-03191652/file/BPH_CPT_2021_Stanke-Labesque.pdfTest; PUBMED: 33547636; PUBMEDCENTRAL: PMC8013748; WOS: 000657272300001

الإتاحة: https://doi.org/10.1002/cpt.2196Test
https://hal.science/hal-03191652Test
https://hal.science/hal-03191652/documentTest
https://hal.science/hal-03191652/file/BPH_CPT_2021_Stanke-Labesque.pdfTest

المؤلفون: Bartelink, I.H., Bet, P.M., Widmer, N., Guidi, M., Duijvelaar, E., Grob, B., Honeywell, R., Evelo, A., Tielbeek, IPE, Snape, S.D., Hamer, H., Decosterd, L.A., Jan Bogaard, H., Aman, J., Swart, E.L.

المصدر: CPT, vol. 10, no. 12, pp. 1497-1511

مصطلحات موضوعية: Acute-Phase Proteins/metabolism, Aged, 80 and over, COVID-19/blood, COVID-19/drug therapy, Female, Humans, Imatinib Mesylate/blood, Imatinib Mesylate/therapeutic use, Male, Middle Aged, Protein Binding/drug effects, Protein Binding/physiology, Protein Kinase Inhibitors/blood, Protein Kinase Inhibitors/therapeutic use

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/34608769; info:eu-repo/semantics/altIdentifier/eissn/2163-8306; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_1F1A8DF396803; https://serval.unil.ch/notice/serval:BIB_1F1A8DF39680Test; urn:issn:2163-8306; https://serval.unil.ch/resource/serval:BIB_1F1A8DF39680.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1F1A8DF396803Test

الإتاحة: https://doi.org/10.1002/psp4.12718Test
https://serval.unil.ch/notice/serval:BIB_1F1A8DF39680Test
https://serval.unil.ch/resource/serval:BIB_1F1A8DF39680.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1F1A8DF396803Test

المؤلفون: Jodaitis, Léni, Van Oene, Thomas, Martens, Chloé

المصدر: International journal of molecular sciences, 22 (14

مصطلحات موضوعية: Sciences exactes et naturelles, Sciences bio-médicales et agricoles, Animals, Cell Membrane -- metabolism, Humans, Membrane Lipids -- metabolism, Membrane Proteins -- metabolism, Protein Binding -- physiology, cryo-electron microscopy, double electron–electron resonance, hydrogen–deuterium exchange mass spectrometry, lipid–protein interaction, membrane protein, native mass spectrometry, single-molecule Förster resonance energy transfer

وصف الملف: 1 full-text file(s): application/pdf

العلاقة: uri/info:doi/10.3390/ijms22147267; uri/info:pii/ijms22147267; uri/info:pmid/34298884; uri/info:scp/85109023184; uri/info:pmcid/PMC8306737; https://dipot.ulb.ac.be/dspace/bitstream/2013/337999/1/doi_321643.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/337999Test

الإتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/337999Test

المؤلفون: Özenver, Nadire, Abdelfatah, Sara, Klinger, Anette, Fleischer, Edmond, Efferth, Thomas

المصدر: http://lobid.org/resources/99370674913906441Test#!, 39(2):348-361.

مصطلحات موضوعية: Azepines/antagonists, Dose-Response Relationship, Drug [MeSH], Pyrimidines/pharmacology [MeSH], Multiple myeloma, Cell Line, Tumor [MeSH], Aurora Kinase A/antagonists, Cancer, Humans [MeSH], Aminoglycosides/pharmacology [MeSH], Targeted chemotherapy, Pyrimidines/antagonists, Azepines/pharmacology [MeSH], Preclinical Studies, Protein Binding/physiology [MeSH], Multiple Myeloma/drug therapy [MeSH], Natural product, precision medicine, Cell Cycle [MeSH]

العلاقة: https://repository.publisso.de/resource/frl:6468394Test; https://doi.org/10.1007/s10637-020-01012-2Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551148Test/

الإتاحة: https://doi.org/10.1007/s10637-020-01012-2Test
https://repository.publisso.de/resource/frl:6468394Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551148Test/

المساهمون: Others, Aneesh Sivaraman, Dae Gyu Kim, Deepak Bhattarai, Minkyoung Kim, Hwa Young Lee, Semi Lim, Jiwon Kong, Ja-Il Goo, Seunghwan Shim, Seungbeom Lee, Young-Ger Suh, Yongseok Choi, Sunghoon Kim, Kyeong Lee

مصطلحات موضوعية: A549 Cells, Animals, Antineoplastic Agents / chemical synthesis, Antineoplastic Agents / metabolism, Antineoplastic Agents / pharmacology, Arylsulfonates / chemical synthesis, Arylsulfonates / metabolism, Arylsulfonates / pharmacology, CHO Cells, Cricetinae, Cricetulus, Drug Development / methods, Female, Humans, Mice, Inbred BALB C, Nude, Nuclear Proteins / antagonists & inhibitors, Nuclear Proteins / metabolism, Protein Binding / physiology, Protein Structure, Secondary, Tertiary, Structure-Activity Relationship, Xenograft Model Antitumor Assays / methods

العلاقة: JOURNAL OF MEDICINAL CHEMISTRY; J01588; OAK-2022-10356; https://ir.ymlib.yonsei.ac.kr/handle/22282913/194849Test; T999202049; JOURNAL OF MEDICINAL CHEMISTRY, Vol.63(10) : 5139-5158, 2020-03

الإتاحة: https://doi.org/10.1021/acs.jmedchem.9b01961Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/194849Test

المؤلفون: Ivo P E Tielbeek, Richard Honeywell, Bram Grob, Pierre M Bet, Harm Jan Bogaard, Monia Guidi, Erik Duijvelaar, Imke H Bartelink, Eleonora L Swart, Nicolas Widmer, Laurent A. Decosterd, Jurjan Aman, Amanda Evelo, Sue D Snape, Henrike Hamer

المساهمون: Clinical pharmacology and pharmacy, APH - Mental Health, APH - Personalized Medicine, Amsterdam Neuroscience - Mood, Anxiety, Psychosis, Stress & Sleep, Pulmonary medicine, Laboratory Medicine, ACS - Pulmonary hypertension & thrombosis, ACS - Microcirculation

المصدر: CPT: Pharmacometrics & Systems Pharmacology
CPT, vol. 10, no. 12, pp. 1497-1511
Bartelink, I H, Bet, P M, Widmer, N, Guidi, M, Duijvelaar, E, Grob, B, Honeywell, R, Evelo, A, Tielbeek, I P E, Snape, S D, Hamer, H, Decosterd, L A, Bogaard, H J, Aman, J & Swart, E L 2021, ' Elevated acute phase proteins affect pharmacokinetics in COVID-19 trials : lessons from the CounterCovid-imatinib-study ', CPT: Pharmacometrics and Systems Pharmacology, vol. 10, no. 12, pp. 1497-1511 . https://doi.org/10.1002/psp4.12718Test
CPT: Pharmacometrics and Systems Pharmacology, 10(12), 1497-1511. Wiley-Blackwell
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 12, Pp 1497-1511 (2021)

مصطلحات موضوعية: Male, medicine.medical_specialty, Cmax, Orosomucoid, RM1-950, 030226 pharmacology & pharmacy, Gastroenterology, Article, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Internal medicine, hemic and lymphatic diseases, medicine, Humans, Pharmacology (medical), Protein Kinase Inhibitors, neoplasms, Aged, Aged, 80 and over, GiST, biology, Acute-Phase Proteins/metabolism, COVID-19/blood, COVID-19/drug therapy, Female, Imatinib Mesylate/blood, Imatinib Mesylate/therapeutic use, Middle Aged, Protein Binding/drug effects, Protein Binding/physiology, Protein Kinase Inhibitors/blood, Protein Kinase Inhibitors/therapeutic use, business.industry, Research, Albumin, Acute-phase protein, COVID-19, Imatinib, Confidence interval, 3. Good health, COVID-19 Drug Treatment, 030220 oncology & carcinogenesis, Modeling and Simulation, biology.protein, Imatinib Mesylate, Therapeutics. Pharmacology, business, medicine.drug, Acute-Phase Proteins, Protein Binding

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b0113a10ff46f52c554a392c3057f2Test
https://doi.org/10.1002/psp4.12718Test

المساهمون: College of Medicine, Dept. of Biochemistry & Molecular Biology, Bu-Nam Jeon, Jae-Hyeon Yoon, Dohyun Han, Min-Kyeong Kim, Youngsoo Kim, Seo-Hyun Choi, Jiyang Song, Kyung-Sup Kim, Kunhong Kim, Man-Wook Hur, Kim, Kun Hong, Kim, Kyung Sup, Jeon, Bu Nam, Hur, Man Wook

مصطلحات موضوعية: Acetylation, Animals, Apoptosis/physiology, Apoptosis Regulatory Proteins/metabolism, Cell Line, Tumor, Cell Proliferation/physiology, Cyclin-Dependent Kinase Inhibitor p21/metabolism, DNA/metabolism, DNA Damage/physiology, DNA-Binding Proteins/metabolism, Down-Regulation/physiology, E1A-Associated p300 Protein, HCT116 Cells, HEK293 Cells, Humans, Promoter Regions, Genetic/physiology, Protein Binding/physiology, Protein Processing, Post-Translational/physiology, Puma/metabolism, Transcriptional Activation/physiology, Tumor Suppressor Protein p53/metabolism, Zinc Fingers/physiology, Apoptosis, PUMA, Post-translational modification, ZNF509S1 (ZBTB49), p53

العلاقة: BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS; J00288; OAK-2017-04143; https://ir.ymlib.yonsei.ac.kr/handle/22282913/160602Test; https://www.sciencedirect.com/science/article/pii/S1874939917300962Test; T201702722; BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, Vol.1860(9) : 962-972, 2017

الإتاحة: https://doi.org/10.1016/j.bbagrm.2017.07.008Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/160602Test
https://www.sciencedirect.com/science/article/pii/S1874939917300962Test

المؤلفون: South, Kieron, Freitas, Marta O, Lane, David A

المصدر: South , K , Freitas , M O & Lane , D A 2017 , ' A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor ' , The Journal of biological chemistry , vol. 292 , no. 14 , pp. 5760-5769 . https://doi.org/10.1074/jbc.M117.776732Test

مصطلحات موضوعية: ADAMTS13 Protein/chemistry, HEK293 Cells, Humans, Models, Chemical, Protein Binding/physiology, Protein Domains, von Willebrand Factor/chemistry

الإتاحة: https://doi.org/10.1074/jbc.M117.776732Test
https://research.manchester.ac.uk/en/publications/5f9f0e14-26a5-40a4-9011-2ed0e18d8820Test

المؤلفون: Smulski, C.R., Kury, P., Seidel, L.M., Staiger, H.S., Edinger, A.K., Willen, L., Seidl, M., Hess, H., Salzer, U., Rolink, A.G., Rizzi, M., Schneider, P., Eibel, H.

المصدر: Cell reports, vol. 18, no. 9, pp. 2189-2202

مصطلحات موضوعية: ADAM Proteins/metabolism, B-Cell Activating Factor/metabolism, B-Cell Activation Factor Receptor/metabolism, B-Lymphocyte Subsets/metabolism, Cell Line, Cell Survival/physiology, Humans, Peptide Hydrolases/metabolism, Protein Binding/physiology, Transmembrane Activator and CAML Interactor Protein/metabolism, ADAM10, ADAM17, B cell, BAFF-receptor, BAFFR, TACI, ectodomain shedding, germinal center, metalloprotease, processing, survival

وصف الملف: application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28249164; info:eu-repo/semantics/altIdentifier/eissn/2211-1247; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_1C83052CD3BC3; https://serval.unil.ch/notice/serval:BIB_1C83052CD3BCTest; https://serval.unil.ch/resource/serval:BIB_1C83052CD3BC.P001/REF.pdfTest; http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1C83052CD3BC3Test

الإتاحة: https://doi.org/10.1016/j.celrep.2017.02.005Test
https://serval.unil.ch/notice/serval:BIB_1C83052CD3BCTest
https://serval.unil.ch/resource/serval:BIB_1C83052CD3BC.P001/REF.pdfTest
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_1C83052CD3BC3Test

المؤلفون: Tuominen, Lauri, Miettunen, Jouko, Cannon, Dara M, Drevets, Wayne C, Frokjaer, Vibe G, Hirvonen, Jussi, Ichise, Masanori, Jensen, Peter S, Keltikangas-Järvinen, Liisa, Klaver, Jacqueline M, Knudsen, Gitte M, Takano, Akihiro, Suhara, Tetsuya, Hietala, Jarmo

المصدر: Tuominen , L , Miettunen , J , Cannon , D M , Drevets , W C , Frokjaer , V G , Hirvonen , J , Ichise , M , Jensen , P S , Keltikangas-Järvinen , L , Klaver , J M , Knudsen , G M , Takano , A , Suhara , T & Hietala , J 2017 , ' Neuroticism Associates with Cerebral in Vivo Serotonin Transporter Binding Differently in Males and Females ' , International Journal of Neuropsychopharmacology , vol. 20 , no. 12 , pp. 963-970 . https://doi.org/10.1093/ijnp/pyx071Test

مصطلحات موضوعية: Adolescent, Adult, Cerebral Cortex/diagnostic imaging, Female, Humans, International Cooperation, Male, Middle Aged, Neuroticism, Positron-Emission Tomography, Protein Binding/physiology, Regression Analysis, Serotonin Plasma Membrane Transport Proteins/metabolism, Sex Characteristics, Young Adult

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1093/ijnp/pyx071Test
https://curis.ku.dk/portal/da/publications/neuroticism-associates-with-cerebral-in-vivo-serotonin-transporterTest-binding-differently-in-males-and-females(d4fc9bef-c54d-4f39-a7f6-317ef7350b9f).html
https://curis.ku.dk/ws/files/193901153/pyx071.pdfTest