المؤلفون: Homer, Joshua A., Koelln, Rebecca A., Barrow, Andrew S., Gialelis, Timothy L., Boiarska, Zlata, Steinohrt, Nikita S., Lee, Erinna F., Yang, Wen-Hsuan, Johnson, Robert M., Chung, Taemoon, Habowski, Amber N., Vishwakarma, Dharmendra S., Bhunia, Debmalya, Avanzi, Charlotte, Moorhouse, Adam D., Jackson, Mary, Tuveson, David A., Lyons, Scott K., Lukey, Michael J., Fairlie, W. Douglas, Haider, Shozeb M., Steinmetz, Michel O., Prota, Andrea E., Moses, John E.

المساهمون: National Cancer Institute, La Trobe University, New York Community Trust, American Cancer Society, F. M. Kirby Foundation, METAvivor, Australian Research Council, Lustgarten Foundation, Victorian Cancer Agency, Cold Spring Harbor Laboratory, Northwell Health, Starr Foundation, Swim Across America, U.S. Department of Defense, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, University of Minnesota

المصدر: Chemical Science ; volume 15, issue 11, page 3879-3892 ; ISSN 2041-6520 2041-6539

الإتاحة: https://doi.org/10.1039/d3sc05729aTest
http://pubs.rsc.org/en/content/articlepdf/2024/SC/D3SC05729ATest

المؤلفون: Prota, Andrea E., Lucena-Agell, Daniel, Ma, Yuntao, Estévez-Gallego, Juan, Li, Shuo, Bargsten, Katja, Josa-Prado, Fernando, Altmann, Karl-Heinz, Gaillard, Natacha, Kamimura, Shinji, Mühlethaler, Tobias, Gago, Federico, Oliva, María A., Steinmetz, Michel O., Fang, Wei-Shuo, Díaz, José Fernando

المساهمون: Ministerio de Ciencia e Innovación (España), Consejo Superior de Investigaciones Científicas (España), Fundación Tatiana Pérez de Guzmán el Bueno, European Commission, Swiss National Science Foundation, Japan Society for the Promotion of Science, National Natural Science Foundation of China, Chinese Academy of Medical Sciences, Prota, Andrea E., Lucena-Agell, Daniel, Estévez-Gallego, Juan, Josa-Prado, Fernando, Altmann, Karl-Heinz, Gaillard, Natacha, Kamimura, Shinji, Mühlethaler, Tobias, Gago, Federico, Oliva, María A., Steinmetz, Michel O., Díaz, José Fernando

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-104545RB-I00/ES/BASES ESTRUCTURALES DE LA NEUROTOXICIDAD POR ANTITUMORALES DIRIGIDOS CONTRA TUBULINA: HACIA MEJORES MODULADORES DE MICROTUBULOS CONTRA CANCER Y ENFERMEDADES NEURODEGENERATIVAS/; info:eu-repo/grantAgreement/EC/H2020/860070; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-104070RB-C22/ES/ESTUDIOS BIOQUIMICOS Y DE MODELADO MOLECULAR PARA EL DISEÑO, CRIBADO Y CARACTERIZACION DE ENTIDADES QUIMICAS INNOVADORAS FRENTE A LEISHMANIASIS E INFECCIONES POR RNA-VIRUS/; Publisher's version; https://doi.org/10.7554/eLife.84791Test; Sí; eLife 12: e84791 (2023); http://hdl.handle.net/10261/306117Test

الإتاحة: https://doi.org/10.7554/eLife.84791Test
http://hdl.handle.net/10261/306117Test

المؤلفون: Estévez-Gallego, Juan, Álvarez-Bernad, Beatriz, Benet, Pera, Wullschleger, Christoph, Raes, Olivier, Menche, Dirk, Martínez, Juan Carlos, Lucena-Agell, Daniel, Prota, Andrea E., Bonato, Francesca, Bargsten, Katja, Cornelus, Jelle, Giménez-Abián, Juan F., Northcote, Peter, Steinmetz, Michel O., Kamimura, Shinji, Altmann, Karl-Heinz, Paterson, Ian, Gago, Federico, Van der Eycken, Johan, Díaz, José Fernando, Oliva, María A.

المساهمون: Ministerio de Ciencia e Innovación (España), Consejo Superior de Investigaciones Científicas (España), European Commission, Fundación Tatiana Pérez de Guzmán el Bueno, Swiss National Science Foundation, Ministerio de Universidades (España), Paul Scherrer Institute (Switzerland), European Synchrotron Radiation Facility, Club Escola Hungaresa de Esgrima de Pontevedra, Estévez-Gallego, Juan, Álvarez-Bernad, Beatriz, Menche, Dirk, Lucena-Agell, Daniel, Prota, Andrea E., Bonato, Francesca, Giménez-Abián, Juan F., Northcote, Peter, Steinmetz, Michel O., Kamimura, Shinji, Altmann, Karl-Heinz, Paterson, Ian, Gago, Federico, Van der Eycken, Johan, Díaz, José Fernando, Oliva, María A.

مصطلحات موضوعية: Microtubule-stabilizing agents, Peloruside, Laulimalide, Tubulin, Microtubules

العلاقة: #PLACEHOLDER_PARENT_METADATA_VALUE#; info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020/PID2019-104545RB-I00/ES/BASES ESTRUCTURALES DE LA NEUROTOXICIDAD POR ANTITUMORALES DIRIGIDOS CONTRA TUBULINA: HACIA MEJORES MODULADORES DE MICROTUBULOS CONTRA CANCER Y ENFERMEDADES NEURODEGENERATIVAS/; Publisher's version; https://doi.org/10.1016/j.str.2022.11.006Test; Sí; Structure 31 (2023); http://hdl.handle.net/10261/287910Test; http://dx.doi.org/10.13039/501100004219Test; http://dx.doi.org/10.13039/501100001671Test; http://dx.doi.org/10.13039/501100004837Test; http://dx.doi.org/10.13039/501100000780Test; http://dx.doi.org/10.13039/501100003339Test; http://dx.doi.org/10.13039/501100010805Test

الإتاحة: https://doi.org/10.1016/j.str.2022.11.006Test
https://doi.org/10.13039/501100004219Test
https://doi.org/10.13039/501100001671Test
https://doi.org/10.13039/501100004837Test
https://doi.org/10.13039/501100000780Test
https://doi.org/10.13039/501100003339Test
https://doi.org/10.13039/501100010805Test
http://hdl.handle.net/10261/287910Test

المؤلفون: Matthew, Susan, Chen, Qi-Yin, Ratnayake, Ranjala, Fermaintt, Charles S., Lucena-Agell, Daniel, Bonato, Francesca, Prota, Andrea E., Lim, Seok Ting, Wang, Xiaomeng, Díaz, J. Fernando, Risinger, April L., Paul, Valerie J., Oliva, Maria Ángela, Luesch, Hendrik

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar 01. 118(9), 1-11.

الوصول الحر: https://www.jstor.org/stable/27027426Test

المؤلفون: Boiarska, Zlata, Pérez-Peña, Helena, Abel, Anne-Catherine, Marzullo, Paola, Álvarez-Bernad, Beatriz, Bonato, Francesca, Santini, Benedetta, Horvath, Dragos, Lucena-Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Díaz, J Fernando, Prota, Andrea E, Pieraccini, Stefano, Passarella, Daniele

المساهمون: Z. Boiarska, H. Pérez-Peña, A. Abel, P. Marzullo, B. Álvarez-Bernad, F. Bonato, B. Santini, D. Horvath, D. Lucena-Agell, F. Vasile, M. Sironi, J.F. Díaz, A.E. Prota, S. Pieraccini, D. Passarella

مصطلحات موضوعية: chemical probe, maytansinoid, maytansinol functionalization, microtubule, tubulin, Settore CHIM/06 - Chimica Organica

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36468686; info:eu-repo/semantics/altIdentifier/wos/WOS:000905833100001; volume:29; issue:5; firstpage:1; lastpage:12; numberofpages:12; journal:CHEMISTRY-A EUROPEAN JOURNAL; https://hdl.handle.net/2434/952967Test; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85145101196

الإتاحة: https://doi.org/10.1002/chem.202203431Test
https://hdl.handle.net/2434/952967Test

المؤلفون: Jost, Marco, Chen, Yuwen, Gilbert, Luke A, Horlbeck, Max A, Krenning, Lenno, Menchon, Grégory, Rai, Ankit, Cho, Min Y, Stern, Jacob J, Prota, Andrea E, Kampmann, Martin, Akhmanova, Anna, Steinmetz, Michel O, Tanenbaum, Marvin E, Weissman, Jonathan S

المصدر: Molecular Cell. 68(1)

مصطلحات موضوعية: Biological Sciences, Biotechnology, Human Genome, Genetics, Orphan Drug, Cancer, Rare Diseases, Aetiology, Development of treatments and therapeutic interventions, 2.1 Biological and endogenous factors, 5.1 Pharmaceuticals, Antineoplastic Agents, CRISPR-Cas Systems, Colchicine, Drug Resistance, Neoplasm, Gene Expression Regulation, Neoplastic, Genetic Testing, Genetic Vectors, Glycine, HeLa Cells, Humans, K562 Cells, Kinesins, Lentivirus, Microtubules, Mutation, Myelodysplastic Syndromes, RNA, Guide, Kinetoplastida, Recombinant Fusion Proteins, Small Molecule Libraries, Sulfones, Tubulin, Tubulin Modulators, Vinblastine, Hela Cells, CRISPRa, CRISPRi, chemical genetics, drug mechanism of action, drug target identification, genome-wide CRISPR screening, microtubules, rigosertib, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences, Health sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1d37n4k6Test

المؤلفون: Wieczorek, Michal, Tcherkezian, Joseph, Bernier, Cynthia, Prota, Andrea E, Chaaban, Sami, Rolland, Yannève, Godbout, Claude, Hancock, Mark A, Arezzo, Joseph C, Ocal, Ozhan, Rocha, Cecilia, Olieric, Natacha, Hall, Anita, Ding, Hui, Bramoullé, Alexandre, Annis, Matthew G, Zogopoulos, George, Harran, Patrick G, Wilkie, Thomas M, Brekken, Rolf A, Siegel, Peter M, Steinmetz, Michel O, Shore, Gordon C, Brouhard, Gary J, Roulston, Anne

المصدر: Science Translational Medicine. 8(365)

مصطلحات موضوعية: Neurosciences, Cancer, Neurodegenerative, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Animals, Antineoplastic Agents, Cell Line, Tumor, Crystallography, X-Ray, Dimerization, Genomics, Humans, Lactams, Macrocyclic, Mice, Microscopy, Electron, Microtubules, Mitosis, Neoplasm Transplantation, Neurons, Oxazoles, Tubulin, Vinblastine, Vinca Alkaloids, Vinorelbine, Biological Sciences, Medical and Health Sciences

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/9dr6h535Test

المؤلفون: Abel, Anne-Catherine, Mühlethaler, Tobias, Dessin, Cedric, Schachtsiek, Thomas, Sammet, Benedikt, Sharpe, Timothy, Steinmetz, Michel O, Sewald, Norbert, Prota, Andrea E

العلاقة: info:eu-repo/semantics/altIdentifier/issn/1083-351X; info:eu-repo/semantics/altIdentifier/pmid/38735475; https://pub.uni-bielefeld.de/record/2989902Test

الإتاحة: https://doi.org/10.1016/j.jbc.2024.107363Test
https://pub.uni-bielefeld.de/record/2989902Test

المؤلفون: Marzullo, Paola, Boiarska, Zlata, Perez-Pena, Helena, Abel, Anne-Catherine, Álvarez-Bernad, Beatriz, Lucena-Agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Altmann, Karl-Heinz, Prota, Andrea E., Díaz, J. Fernando, Pieraccini, Stefano, Passarella, Daniele

المصدر: Chemistry - A European Journal, 28 (2)

مصطلحات موضوعية: maytansinol, maytansine binding site, tubulin, microtubules, tubulin binders

وصف الملف: application/application/pdf

العلاقة: info:eu-repo/semantics/altIdentifier/wos/000723218300001; http://hdl.handle.net/20.500.11850/518611Test

الإتاحة: https://doi.org/20.500.11850/518611Test
https://doi.org/10.3929/ethz-b-000518611Test
https://doi.org/10.1002/chem.202103520Test
https://hdl.handle.net/20.500.11850/518611Test

المؤلفون: Boiarska, Zlata, Pérez‐peña, Helena, Abel, Anne‐catherine, Marzullo, Paola, Álvarez‐bernad, Beatriz, Bonato, Francesca, Santini, Benedetta, Horvath, Dragos, Lucena‐agell, Daniel, Vasile, Francesca, Sironi, Maurizio, Díaz, J. Fernando, Prota, Andrea, E, Pieraccini, Stefano, Passarella, Daniele

المساهمون: Università degli Studi di Milano = University of Milan (UNIMI), Università degli Studi di Milano-Bicocca = University of Milano-Bicocca (UNIMIB), Paul Scherrer Institute (PSI), Centro de Investigaciones Biológicas (CSIC), Consejo Superior de Investigaciones Cientificas = Spanish National Research Council (CSIC), Chimie de la matière complexe (CMC), Université de Strasbourg (UNISTRA)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS)

المصدر: ISSN: 0947-6539.

مصطلحات موضوعية: [CHIM.THER]Chemical Sciences/Medicinal Chemistry

العلاقة: hal-04244004; https://hal.science/hal-04244004Test; https://hal.science/hal-04244004/documentTest; https://hal.science/hal-04244004/file/Maytans4HAL.pdfTest

الإتاحة: https://doi.org/10.1002/chem.202203431Test
https://hal.science/hal-04244004Test
https://hal.science/hal-04244004/documentTest
https://hal.science/hal-04244004/file/Maytans4HAL.pdfTest