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1دورية أكاديمية
المؤلفون: Cremer, Tom, Hoelen, Hanneke, van de Weijer, Michael L, Janssen, George M, Costa, Ana I, van Veelen, Peter A, Lebbink, Robert Jan, Wiertz, Emmanuel J H J
المساهمون: MMB Research line 3a, Infection & Immunity
مصطلحات موضوعية: Antigen Presentation/immunology, Autoantigens/metabolism, Diabetes Mellitus, Type 1/immunology, Endoplasmic Reticulum-Associated Degradation, Humans, Insulin-Secreting Cells/metabolism, Proinsulin/metabolism, Proteolysis, Ubiquitin-Conjugating Enzymes/metabolism, Journal Article
وصف الملف: application/pdf
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2دورية أكاديمية
المؤلفون: Atla, Goutham, Bonàs-Guarch, Silvia, Cuenca-Ardura, Mirabai, Beucher, Anthony, Crouch, Daniel J. M., Garcia-Hurtado, Javier, Moran, Ignasi, Irimia, Manuel, Prasad, Rashmi B., Gloyn, Anna L., Marselli, Lorella, Suleiman, Mara, Berney, Thierry, de Koning, Eelco J. P., Kerr-Conte, Julie, Pattou, Francois, Todd, John A., Piemonti, Lorenzo, Ferrer, Jorge, the T2DSystems Consortium
المصدر: ISSN: 1474-7596 ; Genome biology, vol. 23, no. 1 (2022) 196.
مصطلحات موضوعية: info:eu-repo/classification/ddc/617, Beta cells, CTRB2, Diabetes pathophysiology, G-protein signaling, Pancreatic beta-cells, Pancreatic islets, Quantitative trait loci, RNA splicing, Senescence, TWAS, Type 1 diabetes, Type 2 diabetes, Diabetes Mellitus, Type 1 / genetics, Type 1 / metabolism, Type 2 / genetics, Exodeoxyribonucleases / genetics, Exodeoxyribonucleases / metabolism, Humans, Islets of Langerhans / metabolism, Proinsulin / genetics, Proinsulin / metabolism, Protein Isoforms / genetics, RNA, Long Noncoding / metabolism
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/36109769; info:eu-repo/grantAgreement/EC/H2020/789055/EU/Expanding the genetic etiological and diagnostic spectrum of monogenic diabetes mellitus/DecodeDiabetes; info:eu-repo/grantAgreement/EC/H2020/667191/EU/Development of a systems biomedicine approach for risk identification, prevention and treatment of type 2 diabetes/T2DSystems; info:eu-repo/grantAgreement/EC/H2020/643062/EU/Computational and functional annotation of genomic elements during development of the model vertebrate zebrafish/ZENCODE-ITN; info:eu-repo/grantAgreement/EC/H2020/874710/EU/Human Cell Atlas of the Pancreas/ESPACE; https://archive-ouverte.unige.ch/unige:166264Test; unige:166264
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3دورية أكاديمية
المصدر: http://lobid.org/resources/99370676916506441Test#!, 63(10):1981-1989.
مصطلحات موضوعية: Type 2 diabetes, Post-transcriptional regulation, Protein Precursors/genetics [MeSH], Type 1 diabetes, Beta cell, Insulin maturation, Gene Expression Regulation [MeSH], Glucose/metabolism [MeSH], Insulin/genetics [MeSH], Insulin biosynthesis, RNA Processing, Post-Transcriptional [MeSH], Proinsulin/biosynthesis [MeSH], RNA, Messenger/metabolism [MeSH], Protein Precursors/biosynthesis [MeSH], Proinsulin conversion, Proinsulin/genetics [MeSH], Insulin/biosynthesis [MeSH], Humans [MeSH], Proinsulin/metabolism [MeSH], Protein Biosynthesis [MeSH], Protein Precursors/metabolism [MeSH], Protein Folding [MeSH], Insulin Secretion [MeSH], Review, Diabetes Mellitus, Type 2/metabolism [MeSH], Type 1/metabolism [MeSH], Secretory Vesicles/metabolism [MeSH]
العلاقة: https://repository.publisso.de/resource/frl:6469022Test; https://doi.org/10.1007/s00125-020-05192-7Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476993Test/
الإتاحة: https://doi.org/10.1007/s00125-020-05192-7Test
https://repository.publisso.de/resource/frl:6469022Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7476993Test/ -
4دورية أكاديمية
المؤلفون: Roomp, Kirsten, Kristinsson, Hjalti, Schvartz, Domitille, Ubhayasekera, Kumari, Sargsyan, Ernest, Manukyan, Levon, Chowdhury, Azazul, Manell, Hannes, Satagopam, Venkata, Groebe, Karlfried, Schneider, Reinhard, Bergquist, Jonas, Sanchez, Jean-Charles, Bergsten, Peter
المصدر: ISSN: 1932-6203 ; PLOS ONE, vol. 12, no. 4 (2017) e0176391.
مصطلحات موضوعية: info:eu-repo/classification/ddc/576, Diabetes Mellitus, Type 2/metabolism, Female, Gene Expression Regulation/drug effects, Glucose/metabolism, Humans, Insulin/secretion, Islets of Langerhans/drug effects/metabolism/secretion, Lipid Metabolism/drug effects, Male, Middle Aged, Palmitates/pharmacology, Proinsulin/metabolism, Proteomics, Time Factors
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/28448538; https://archive-ouverte.unige.ch/unige:100598Test; unige:100598
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5دورية أكاديمية
المؤلفون: Kallas, Åsa
المصدر: Diabetes (Stockholm). (2):10
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6دورية أكاديمية
المساهمون: Young Mi Park, Seonock Woo, Geun Taek Lee, Ji-Yun Ko, Yongho Lee, Zheng-Shan Zhao, Hye Joo Kim, Chul Woo Ahn, Bong Soo Cha, Kyung-Sup Kim, Cheol Won Park, Hyun Chul Lee, Kim, Kyung Sup, Ahn, Chul Woo, Lee, Yong Ho, Lee, Hyun Chul, Cha, Bong Soo
مصطلحات موضوعية: Animals, Genetically Modified, Blood Glucose/metabolism, Cytoskeletal Proteins/pharmacology, Dependovirus/genetics, Diabetes Mellitus, Experimental/metabolism, Experimental/therapy, Gene Transfer Techniques, Genetic Therapy, Genetic Vectors, Glucose Tolerance Test, Glycated Hemoglobin A/metabolism, Insulin/genetics, Insulin/metabolism, Liver/metabolism, Male, Portal Vein, Proinsulin/metabolism, Pyrin, Rats, Sprague-Dawley, Safety, Treatment Outcome, basal insulin, gene therapy, recombinant viral vectors
العلاقة: JOURNAL OF GENE MEDICINE; J01419; OAK-2005-11323; https://ir.ymlib.yonsei.ac.kr/handle/22282913/150041Test; T200500497; JOURNAL OF GENE MEDICINE, Vol.7(5) : 621-629, 2005
الإتاحة: https://doi.org/10.1002/jgm.708Test
https://ir.ymlib.yonsei.ac.kr/handle/22282913/150041Test -
7دورية أكاديمية
المؤلفون: Wang, Haiyan, Iezzi, M., Theander, Sten, Antinozzi, P. A., Gauthier, B. R., Halban, Philippe A., Wollheim, Claes
المصدر: ISSN: 0012-186X ; Diabetologia, vol. 48, no. 4 (2005) p. 720-731.
مصطلحات موضوعية: info:eu-repo/classification/ddc/616, Adenosine Triphosphate/metabolism, Animals, Calcium Signaling/physiology, Cell Line, Tumor, Cyclic AMP/metabolism, Dose-Response Relationship, Drug, Doxycycline/pharmacology, Exocytosis/physiology, Gene Expression/drug effects/genetics, Gene Expression Regulation, Neoplastic/drug effects, Glucokinase/genetics, Glucose/metabolism/pharmacology, Glycolysis, Homeodomain Proteins/genetics/metabolism/ physiology, Human Growth Hormone/genetics/secretion, Insulin/ secretion, Islets of Langerhans/drug effects/metabolism, Mitochondria/metabolism, Mutation, Proinsulin/ metabolism, Proprotein Convertases/genetics, RNA, Messenger/genetics/metabolism, Rats, Receptor Protein-Tyrosine Kinases/genetics, Receptor
العلاقة: info:eu-repo/semantics/altIdentifier/pmid/15756539; https://archive-ouverte.unige.ch/unige:9086Test; unige:9086
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8دورية أكاديمية
المؤلفون: Takiishi, Tatiana, Cook, Dana Paulina, Korf, Hannelie, Sebastiani, Guido, Mancarella, Francesca, Cunha, João Paulo Monteiro Carvalho Mori J.P.M., Wasserfall, Clive, Casares, Noelia, Lasarte, Juan José, Steidler, Lothar, Rottiers, Pieter, Dotta, Francesco, Gysemans, Conny, Mathieu, Chantal
المصدر: Diabetes (New York, N.Y.), 66 (2
مصطلحات موضوعية: Diabétologie, Immunologie, Endocrinologie, Biologie cellulaire, Sciences exactes et naturelles, Animals, Antibodies -- pharmacology, Antibodies, Neutralizing -- pharmacology, Blood Glucose -- drug effects -- metabolism, CD3 Complex -- immunology, CD4-Positive T-Lymphocytes -- drug effects -- immunology, CTLA-4 Antigen -- drug effects -- immunology, Diabetes Mellitus -- metabolism, Disease Models, Animal, Forkhead Transcription Factors -- immunology, Glucose Tolerance Test, Immune Tolerance -- drug effects -- immunology, Interleukin-10 -- metabolism, Lactobacillus -- metabolism, Lymphocyte Activation, Mice, Inbred NOD, Pancreas -- drug effects -- pathology, Proinsulin -- metabolism, T-Lymphocytes, Regulatory -- drug effects -- immunology, Transforming Growth Factor beta -- drug effects -- immunology
وصف الملف: 1 full-text file(s): application/pdf
العلاقة: uri/info:doi/10.2337/db15-1625; uri/info:pii/db15-1625; uri/info:pmid/28108611; https://dipot.ulb.ac.be/dspace/bitstream/2013/338061/1/doi_321705.pdfTest; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/338061Test
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9
المؤلفون: Hélène Jousset, Claes B. Wollheim, Jean-Claude Irminger, Alejandra Tomas, Philippe A. Halban, Anne-Lise Prost, Fabienne Jaques, Nicolas Demaurex
المصدر: Endocrinology, Vol. 149, No 5 (2008) pp. 2494-505
مصطلحات موضوعية: Cytosol/metabolism, medicine.medical_treatment, Down-Regulation/drug effects, Stimulation, Cell Communication, Cell Proliferation/drug effects, Mice, Cytosol, Endocrinology, Insulin-Secreting Cells, Insulin Secretion, Insulin, ddc:576.5, RNA, Small Interfering, Cells, Cultured, Oligonucleotide Array Sequence Analysis, Confluency, Contact Inhibition, Cell adhesion molecule, Cadherins, Glucose/pharmacology, Insulin oscillation, Protein Transport, Cell Communication/physiology, Intracellular, Proinsulin, medicine.medical_specialty, Calcium/metabolism, Down-Regulation, Biology, Cell Adhesion/drug effects/genetics, Cadherins/antagonists & inhibitors/metabolism, Internal medicine, Cell Adhesion, medicine, Animals, Secretion, Insulin-Secreting Cells/drug effects/metabolism/physiology/secretion, Cell Proliferation, Insulin/secretion, RNA Small Interfering/pharmacology, Calcium Channels/metabolism/physiology, Contact Inhibition/physiology, Proinsulin/metabolism, Glucose, Basal (medicine), Calcium, Calcium Channels, Cells Cultured
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3b31aff90e033473e4cd2caefbe0cbTest
https://doi.org/10.1210/en.2007-0974Test -
10
المؤلفون: Kampf, Caroline, Lau, T, Olsson, Richard, Leung, P S, Carlsson, Per-Ola
المصدر: Diabetologia. 48(6):1159-67
مصطلحات موضوعية: Administration, Oral, Angiotensin II Type 1 Receptor Blockers/pharmacology, Animals, Glucose/*pharmacology, Injections, Intravenous, Insulin/*secretion, Islets of Langerhans/*blood supply, Islets of Langerhans Transplantation/*physiology, Losartan/administration & dosage/*pharmacology, Male, Mice, Inbred C57BL, Microcirculation/drug effects/*physiology, Models, Animal, Proinsulin/metabolism, Research Support, Non-U.S. Gov't, Subrenal Capsule Assay, Transplantation, Isogeneic/*physiology
وصف الملف: print
الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-79746Test
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=15877216&dopt=CitationTest
النص الكامل