التفاصيل البيبلوغرافية
| العنوان: |
Successful Treatment of Metastatic Primary Cutaneous Adnexal Carcinoma With a PD-1 Inhibitor |
| المؤلفون: |
Patel, Janmesh D., Pozorski, Vincent J., Tavberidze, Nika, Buehler, Darya G., Huang, Wei, Bennett, Daniel D., Ma, Vincent T. |
| المصدر: |
Journal of Immunotherapy ; ISSN 1524-9557 |
| بيانات النشر: |
Ovid Technologies (Wolters Kluwer Health) |
| سنة النشر: |
2024 |
| الوصف: |
Summary: Standard of care treatment for metastatic cutaneous adnexal carcinomas is not well established. In this case report, we highlight the successful use of anti–programmed cell death protein 1 (anti-PD-1) therapy in treating a patient with low tumor mutation burden, microsatellite stable, high programmed death-ligand 1 (PD-L1) gene expression, metastatic primary cutaneous adnexal carcinoma with significant radiographic, and circulating tumor DNA response with durable benefit. Immune checkpoint inhibitors hold promise as a future treatment option in rare instances of metastatic disease from primary skin adnexal carcinoma. Further studies are needed to identify better immune checkpoint inhibitor predictive biomarkers for rare, advanced-stage non-melanoma skin cancers. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| DOI: |
10.1097/cji.0000000000000522 |
| DOI: |
10.1097/CJI.0000000000000522 |
| الإتاحة: |
https://doi.org/10.1097/cji.0000000000000522Test |
| رقم الانضمام: |
edsbas.DF15FDA0 |
| قاعدة البيانات: |
BASE |
