المؤلفون: Borcher Møller, Søren Lau, Rasmussen, Michelle H., Li, Jun, Svenningsen, Esben B., Wørmer, Gustav J., Tørring, Thomas, Poulsen, Thomas B.

المصدر: Borcher Møller , S L , Rasmussen , M H , Li , J , Svenningsen , E B , Wørmer , G J , Tørring , T & Poulsen , T B 2024 , ' The Biological Activities of Polyether Ionophore Antibiotic Routiennocin is Independent of Absolute Stereochemistry ' , ChemBioChem , vol. 25 , no. 7 , e202400013 . https://doi.org/10.1002/cbic.202400013Test

مصطلحات موضوعية: Antibiotics, Antimicrobial Resistance, Ionophore, Stereochemistry, Total synthesis, Polyether Polyketides, Ionophores/chemistry, Animals, Mammals/metabolism, Anti-Bacterial Agents/pharmacology

العلاقة: https://pure.au.dk/portal/en/publications/13baf5a2-cb33-428a-8010-5f2d2a694595Test

الإتاحة: https://doi.org/10.1002/cbic.202400013Test
https://pure.au.dk/portal/en/publications/13baf5a2-cb33-428a-8010-5f2d2a694595Test
http://www.scopus.com/inward/record.url?scp=85186258684&partnerID=8YFLogxKTest

المؤلفون: Busk, Morten, Eggertsen, Peter P, Overgaard, Jens, Horsman, Michael R, Tørring, Thomas, Jacobsen, Kristian M, Poulsen, Thomas B

المصدر: Busk , M , Eggertsen , P P , Overgaard , J , Horsman , M R , Tørring , T , Jacobsen , K M & Poulsen , T B 2023 , ' In Vitro Characterization of the Bacteria-derived Hypoxia-selective Cytotoxin BE- 43547 ' , Anticancer Research , vol. 43 , no. 12 , pp. 5319-5329 . https://doi.org/10.21873/anticanres.16735Test

العلاقة: https://pure.au.dk/portal/en/publications/0d1be8b7-3eae-40aa-af10-41652ab0182fTest

الإتاحة: https://doi.org/10.21873/anticanres.16735Test
https://pure.au.dk/portal/en/publications/0d1be8b7-3eae-40aa-af10-41652ab0182fTest

المؤلفون: Mahía, Alejandro, Kiib, Anders E, Nisavic, Marija, Svenningsen, Esben B, Palmfeldt, Johan, Poulsen, Thomas B

المصدر: Mahía , A , Kiib , A E , Nisavic , M , Svenningsen , E B , Palmfeldt , J & Poulsen , T B 2023 , ' α-Lactam Electrophiles for Covalent Chemical Biology ' , Angewandte Chemie - International Edition , vol. 62 , no. 26 , e202304142 . https://doi.org/10.1002/anie.202304142Test

مصطلحات موضوعية: Azirines, Biology, Heterocyclic Compounds, Lactams, Inhibitors, Activity-Based Protein Profiling, Hydrolases, Small Ring Systems

العلاقة: https://pure.au.dk/portal/en/publications/488d9623-8c1d-4c15-9302-dbb3241fdb71Test

الإتاحة: https://doi.org/10.1002/anie.202304142Test
https://pure.au.dk/portal/en/publications/488d9623-8c1d-4c15-9302-dbb3241fdb71Test
http://www.scopus.com/inward/record.url?scp=85159179383&partnerID=8YFLogxKTest

المؤلفون: Waqas, Fakhar H., Shehata, Mahmoud, Elgaher, Walid A M, Lacour, Antoine, Kurmasheva, Naziia, Begnini, Fabio, Kiib, Anders E, Dahlmann, Julia, Chen, Chutao, Pavlou, Andreas, Poulsen, Thomas B, Merkert, Sylvia, Martin, Ulrich, Olmer, Ruth, Olagnier, David, Hirsch, Anna K H, Pleschka, Stephan, Pessler, Frank

المصدر: Waqas , F H , Shehata , M , Elgaher , W A M , Lacour , A , Kurmasheva , N , Begnini , F , Kiib , A E , Dahlmann , J , Chen , C , Pavlou , A , Poulsen , T B , Merkert , S , Martin , U , Olmer , R , Olagnier , D , Hirsch , A K H , Pleschka , S & Pessler , F 2023 , ' NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent ....

مصطلحات موضوعية: Humans, Active Transport, Cell Nucleus, Endothelial Cells/metabolism, Influenza A virus/genetics, Influenza A Virus, H1N1 Subtype/genetics, Karyopherins/metabolism, Kelch-Like ECH-Associated Protein 1/metabolism, NF-E2-Related Factor 2/metabolism, Ribonucleoproteins/metabolism, RNA, Messenger/metabolism, Virus Replication

العلاقة: https://pure.au.dk/portal/en/publications/6d830713-3bee-4c2a-be8e-28c6dcb81c48Test

الإتاحة: https://doi.org/10.1371/journal.ppat.1011506Test
https://pure.au.dk/portal/en/publications/6d830713-3bee-4c2a-be8e-28c6dcb81c48Test
http://www.scopus.com/inward/record.url?scp=85165687834&partnerID=8YFLogxKTest

المؤلفون: Wollesen, Malene, Mikkelsen, Kasper, Tvilum, Marie Selch, Vestergaard, Martin, Wang, Mikala, Meyer, Rikke L, Ingmer, Hanne, Poulsen, Thomas B, Tørring, Thomas

المصدر: Wollesen , M , Mikkelsen , K , Tvilum , M S , Vestergaard , M , Wang , M , Meyer , R L , Ingmer , H , Poulsen , T B & Tørring , T 2023 , ' Polyether Ionophore Antibiotics Target Drug-Resistant Clinical Isolates, Persister Cells, and Biofilms ' , Microbiology Spectrum , vol. 11 , no. 4 , e0062523 . https://doi.org/10.1128/spectrum.00625-23Test

مصطلحات موضوعية: Humans, Animals, Cattle, Ionophores/pharmacology, Anti-Bacterial Agents/therapeutic use, Anti-Infective Agents/pharmacology, Gram-Positive Bacteria, Biofilms, Microbial Sensitivity Tests

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1128/spectrum.00625-23Test
https://curis.ku.dk/portal/da/publications/polyether-ionophore-antibiotics-target-drugresistant-clinical-isolates-persister-cells-and-biofilmsTest(688b867f-e2a3-4fa3-9bf5-016db5c181af).html
https://curis.ku.dk/ws/files/367730675/wollesen_et_al_2023_polyether_ionophore_antibiotics_target_drug_resistant_clinical_isolates_persister_cells_and_biofilms.pdfTest

المؤلفون: Waser, Philipp, Faghtmann, Jonas, Gil‐Ordóñez, Marta, Kristensen, Anne, Svenningsen, Esben B., Poulsen, Thomas B., Jørgensen, Karl Anker

المصدر: Chemistry - A European Journal; 7/5/2024, Vol. 30 Issue 38, p1-9, 9p

المؤلفون: Svenningsen, Esben B., Ottosen, Rasmus N., Jørgensen, Katrine H., Nisavic, Marija, Larsen, Camilla K., Hansen, Bente K., Wang, Yong, Lindorff-Larsen, Kresten, Tørring, Thomas, Hacker, Stephan M., Palmfeldt, Johan, Poulsen, Thomas B.

المصدر: Svenningsen , E B , Ottosen , R N , Jørgensen , K H , Nisavic , M , Larsen , C K , Hansen , B K , Wang , Y , Lindorff-Larsen , K , Tørring , T , Hacker , S M , Palmfeldt , J & Poulsen , T B 2022 , ' The covalent reactivity of functionalized 5-hydroxy-butyrolactams is the basis for targeting of fatty acid binding protein 5 (FABP5) by the neurotrophic agent MT-21 ' , RSC Chemical Biology , vol. 3 , no. 10 , pp. 1216-1229 . https://doi.org/10.1039/d2cb00161fTest

العلاقة: https://pure.au.dk/portal/en/publications/fdb88e93-26d5-4d12-8412-f48fee5cacb2Test

الإتاحة: https://doi.org/10.1039/d2cb00161fTest
https://pure.au.dk/portal/en/publications/fdb88e93-26d5-4d12-8412-f48fee5cacb2Test
http://www.scopus.com/inward/record.url?scp=85141669743&partnerID=8YFLogxKTest

المؤلفون: Casares, Laura, Moreno, Rita, Ali, Kevin X., Higgins, Maureen, Dayalan Naidu, Sharadha, Neill, Graham, Cassin, Lena, Kiib, Anders E., Svenningsen, Esben B., Minassi, Alberto, Honda, Tadashi, Poulsen, Thomas B., Wiel, Clotilde, Sayin, Volkan I., Dinkova-Kostova, Albena T., Olagnier, David, de la Vega, Laureano

المصدر: Casares , L , Moreno , R , Ali , K X , Higgins , M , Dayalan Naidu , S , Neill , G , Cassin , L , Kiib , A E , Svenningsen , E B , Minassi , A , Honda , T , Poulsen , T B , Wiel , C , Sayin , V I , Dinkova-Kostova , A T , Olagnier , D & de la Vega , L 2022 , ' The synthetic triterpenoids CDDO-TFEA and CDDO-Me, but not CDDO, promote nuclear exclusion of BACH1 impairing its activity ' , Redox ....

مصطلحات موضوعية: BACH1, CDDO, HMOX1, NRF2

الإتاحة: https://doi.org/10.1016/j.redox.2022.102291Test
https://pure.au.dk/portal/da/publications/the-synthetic-triterpenoids-cddotfea-and-cddome-but-not-cddo-promote-nuclear-exclusion-of-bach1-impairing-its-activityTest(66402709-7e58-4b88-af6c-815f1189769a).html
http://www.scopus.com/inward/record.url?scp=85126572599&partnerID=8YFLogxKTest

المؤلفون: Olagnier, David, Farahani, Ensieh, Thyrsted, Jacob, Blay-Cadanet, Julia, Herengt, Angela, Idorn, Manja, Hait, Alon, Hernaez, Bruno, Knudsen, Alice, Iversen, Marie Beck, Schilling, Mirjam, Jørgensen, Sofie E., Thomsen, Michelle, Reinert, Line S., Lappe, Michael, Hoang, Huy-Dung, Gilchrist, Victoria H., Hansen, Anne Louise, Ottosen, Rasmus, Nielsen, Camilla G., Møller, Charlotte, van der Horst, Demi, Peri, Suraj, Balachandran, Siddharth, Huang, Jinrong, Jakobsen, Martin, Svenningsen, Esben B., Poulsen, Thomas B., Bartsch, Lydia, Thielke, Anne L., Luo, Yonglun, Alain, Tommy, Rehwinkel, Jan, Alcamí, Antonio, Hiscott, John, Mogensen, Trine H., Paludan, Søren R., Holm, Christian K.

المساهمون: Olagnier, David, Farahani, Ensieh, Thyrsted, Jacob, Blay-Cadanet, Julia, Herengt, Angela, Idorn, Manja, Hait, Alon, Hernaez, Bruno, Knudsen, Alice, Iversen, Marie Beck, Schilling, Mirjam, Jørgensen, Sofie E., Thomsen, Michelle, Reinert, Line S., Lappe, Michael, Hoang, Huy-Dung, Gilchrist, Victoria H., Hansen, Anne Louise, Ottosen, Rasmus, Nielsen, Camilla G., Møller, Charlotte, van der Horst, Demi, Peri, Suraj, Balachandran, Siddharth, Huang, Jinrong, Jakobsen, Martin, Svenningsen, Esben B., Poulsen, Thomas B., Bartsch, Lydia, Thielke, Anne L., Luo, Yonglun, Alain, Tommy, Rehwinkel, Jan, Alcamí, Antonio, Hiscott, John, Mogensen, Trine H., Paludan, Søren R., Holm, Christian K.

العلاقة: https://resolver.sub.uni-goettingen.de/purl?gro-2/83724Test

الإتاحة: https://doi.org/10.1038/s41467-020-18764-3Test
https://resolver.sub.uni-goettingen.de/purl?gro-2/83724Test

المؤلفون: Svenningsen, Esben B, Thyrsted, Jacob, Blay-Cadanet, Julia, Liu, Han, Lin, Shaoquan, Villameriel, Jaime Moyano, Olagnier, David, Idorn, Manja, Paludan, Søren R, Holm, Christian K, Poulsen, Thomas B

المصدر: Svenningsen , E B , Thyrsted , J , Blay-Cadanet , J , Liu , H , Lin , S , Villameriel , J M , Olagnier , D , Idorn , M , Paludan , S R , Holm , C K & Poulsen , T B 2021 , ' Ionophore antibiotic X-206 is a potent inhibitor of SARS-CoV-2 infection in vitro ' , Antiviral Research , vol. 185 , 104988 . https://doi.org/10.1016/j.antiviral.2020.104988Test

مصطلحات موضوعية: Antiviral agent, Coronavirus, Polyether ionophore, SARS-CoV-2, X-206, BROAD-SPECTRUM, CELLS, SALINOMYCIN

العلاقة: https://pure.au.dk/portal/en/publications/58a37903-fa95-4e91-a367-2213ede33eb2Test

الإتاحة: https://doi.org/10.1016/j.antiviral.2020.104988Test
https://pure.au.dk/portal/en/publications/58a37903-fa95-4e91-a367-2213ede33eb2Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7687369/pdf/main.pdfTest