دورية أكاديمية
Evaluation of multi-institutional end-to-end testing for post-operative spine stereotactic body radiation therapy
| العنوان: | Evaluation of multi-institutional end-to-end testing for post-operative spine stereotactic body radiation therapy |
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| المؤلفون: | Tomohisa Furuya, Young K. Lee, Ben R. Archibald-Heeren, Mikel Byrne, Bruno Bosco, Jun H. Phua, Hidetoshi Shimizu, Shimpei Hashimoto, Hiroshi Tanaka, Arjun Sahgal, Katsuyuki Karasawa |
| المصدر: | Physics and Imaging in Radiation Oncology, Vol 16, Iss , Pp 61-68 (2020) |
| بيانات النشر: | Elsevier, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | Post-operative spine SBRT, SABR, Impact of metal hardware, End-to-end test, Multi-institutional phantom study, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Background and purpose: Post-operative spine stereotactic body radiation therapy (SBRT) represents a significant challenge as there are many restrictions on beam geometry to avoid metal hardware as it surrounds the target volume. In this study, an international multi-institutional end-to-end test using an in-house spine phantom was developed and executed. The aim was to evaluate the impact of titanium spine hardware on planned and delivered dose for post-operative spine SBRT. Materials and methods: Five centers performed simulation, planning and irradiation of the spine phantom, with/without titanium metal hardware (MB/B), following our pre-specified protocol. The doses were calculated using the centers’ treatment planning system (TPS) and measured with radiophotoluminescent glass dosimeters (RPLDs) embedded within each phantom. Results: The dose differences between the RPLD measured and calculated doses in the target region were within ± 5% for both phantoms studied. Differences greater than 5% were observed for the spinal cord and the out-of-the target regions due to steeper dose gradient regions that are created in these plans. Dose measurements within ± 3% were observed between RPLDs that were embedded in MB and B inserts. For the spinal cord and the out-of-target regions surrounded by metal hardware, the dose measured using RPLDs was within 3% different near the titanium screws compared to the dose measured near only the metal rods. Conclusion: We have successfully performed the first multi-institutional end-to-end dose analysis using an in-house phantom built specifically for post-operative spine SBRT. The differences observed between the measured and planned doses in the presence of metal hardware were clinically insignificant. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2405-6316 |
| العلاقة: | http://www.sciencedirect.com/science/article/pii/S2405631620300555Test; https://doaj.org/toc/2405-6316Test |
| DOI: | 10.1016/j.phro.2020.09.005 |
| الوصول الحر: | https://doaj.org/article/19fabe0e53874b17ae8e30532dbd2a00Test |
| رقم الانضمام: | edsdoj.19fabe0e53874b17ae8e30532dbd2a00 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 24056316 |
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| DOI: | 10.1016/j.phro.2020.09.005 |