دورية أكاديمية
Cortical similarities in psychiatric and mood disorders identified in federated VBM analysis via COINSTAC
| العنوان: | Cortical similarities in psychiatric and mood disorders identified in federated VBM analysis via COINSTAC |
|---|---|
| المؤلفون: | Rootes-Murdy, K, Panta, S, Kelly, R, Romero, J, Quidé, Y, Cairns, MJ, Loughland, C, Carr, VJ, Catts, SV, Jablensky, A, Green, MJ, Henskens, F, Kiltschewskij, D, Michie, PT, Mowry, B, Pantelis, C, Rasser, PE, Reay, WR, Schall, U, Scott, RJ, Watkeys, OJ, Roberts, G, Mitchell, PB, Fullerton, JM, Overs, BJ, Kikuchi, M, Hashimoto, R, Matsumoto, J, Fukunaga, M, Sachdev, PS, Brodaty, H, Wen, W, Jiang, J, Fani, N, Ely, TD, Lorio, A, Stevens, JS, Ressler, K, Jovanovic, T, van Rooij, SJH, Federmann, LM, Jockwitz, C, Teumer, A, Forstner, AJ, Caspers, S, Cichon, S, Plis, SM, Sarwate, AD, Calhoun, VD, Quide, Yann |
| المصدر: | urn:ISSN:2666-3899 ; Patterns, 100987-100987 |
| بيانات النشر: | Elsevier |
| سنة النشر: | 2024 |
| المجموعة: | UNSW Sydney (The University of New South Wales): UNSWorks |
| مصطلحات موضوعية: | Intellectual and Developmental Disabilities (IDD), Brain Disorders, Mental Illness, Behavioral and Social Science, Mental Health, Depression, Serious Mental Illness, Schizophrenia, Neurosciences, 2 Aetiology, 2.1 Biological and endogenous factors, 3 Good Health and Well Being |
| الوصف: | Structural neuroimaging studies have identified a combination of shared and disorder-specific patterns of gray matter (GM) deficits across psychiatric disorders. Pooling large data allows for examination of a possible common neuroanatomical basis that may identify a certain vulnerability for mental illness. Large-scale collaborative research is already facilitated by data repositories, institutionally supported databases, and data archives. However, these data-sharing methodologies can suffer from significant barriers. Federated approaches augment these approaches by enabling access or more sophisticated, shareable and scaled-up analyses of large-scale data. We examined GM alterations using Collaborative Informatics and Neuroimaging Suite Toolkit for Anonymous Computation, an open-source, decentralized analysis application. Through federated analysis of eight sites, we identified significant overlap in the GM patterns (n = 4,102) of individuals with schizophrenia, major depressive disorder, and autism spectrum disorder. These results show cortical and subcortical regions that may indicate a shared vulnerability to psychiatric disorders. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | unknown |
| العلاقة: | http://hdl.handle.net/1959.4/102077Test; https://unsworks.unsw.edu.au/bitstreams/8a982c6a-e4b9-4cfa-af37-83ca9e06ea4b/downloadTest; https://doi.org/10.1016/j.patter.2024.100987Test |
| DOI: | 10.1016/j.patter.2024.100987 |
| الإتاحة: | https://doi.org/10.1016/j.patter.2024.100987Test http://hdl.handle.net/1959.4/102077Test https://unsworks.unsw.edu.au/bitstreams/8a982c6a-e4b9-4cfa-af37-83ca9e06ea4b/downloadTest |
| حقوق: | open access ; https://purl.org/coar/access_right/c_abf2Test ; CC-BY-NC-ND ; https://creativecommons.org/licenses/by-nc-nd/4.0Test/ ; free_to_read |
| رقم الانضمام: | edsbas.F91F8B4C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.patter.2024.100987 |
|---|