المؤلفون: Shun Hayashi, Hiroko Kawaguchi, Takao Watanabe, Izuru Miyawaki, Tatsuki Fukami, Miki Nakajima

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Physiology, Pharmacology, Biotechnology, Cancer, Biological Sciences not elsewhere classified, Information Systems not elsewhere classified, Tipepidine, drug repositioning, CYP2D6, drug interaction, physiologically based pharmacokinetic modelling

العلاقة: https://figshare.com/articles/journal_contribution/Prediction_of_combination_effect_of_quinidine_on_the_pharmacokinetics_of_tipepidine_using_a_physiologically_based_pharmacokinetic_model/25018370Test

الإتاحة: https://doi.org/10.6084/m9.figshare.25018370.v1Test
https://figshare.com/articles/journal_contribution/Prediction_of_combination_effect_of_quinidine_on_the_pharmacokinetics_of_tipepidine_using_a_physiologically_based_pharmacokinetic_model/25018370Test

المؤلفون: Musther, Helen

المساهمون: Hallifax, David, Rostami-Hochaghan, Amin

مصطلحات موضوعية: 615.1, Drug distribution, Physiologically Based Pharmacokinetic modelling, Volume of distribution

الوصول الحر: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.825903Test

المؤلفون: Julia Macente, Nina Nauwelaerts, Francesca M. Russo, Jan Deprest, Karel Allegaert, Bart Lammens, Rodolfo Hernandes Bonan, Jessica M. Turner, Sailesh Kumar, Andrea Diniz, Frederico S. Martins, Pieter Annaert

مصطلحات موضوعية: Pharmacology, Basic Pharmacology, Clinical Pharmacology and Therapeutics, Clinical Pharmacy and Pharmacy Practice, Pharmaceutical Sciences, Pharmacogenomics, Toxicology (incl. Clinical Toxicology), Pharmacology and Pharmaceutical Sciences not elsewhere classified, physiologically-based pharmacokinetic modelling, PBPK, model informed drug development, MIDD, sildenafil, revatio, congenital diaphragmatic hernia, pregnant women

العلاقة: https://figshare.com/articles/presentation/Presentation1_PBPK-based_dose_finding_for_sildenafil_in_pregnant_women_for_antenatal_treatment_of_congenital_diaphragmatic_hernia_pdf/22267321Test

الإتاحة: https://doi.org/10.3389/fphar.2023.1068153.s001Test
https://figshare.com/articles/presentation/Presentation1_PBPK-based_dose_finding_for_sildenafil_in_pregnant_women_for_antenatal_treatment_of_congenital_diaphragmatic_hernia_pdf/22267321Test

المؤلفون: Leyanis Rodriguez-Vera, Xuefen Yin, Mohammed Almoslem, Karolin Romahn, Brian Cicali, Viera Lukacova, Rodrigo Cristofoletti, Stephan Schmidt

المصدر: Pharmaceutics, Vol 15, Iss 10, p 2486 (2023)

مصطلحات موضوعية: physiologically based pharmacokinetic modelling (PBPK), drug–drug interactions (DDIs), phenytoin, cytochrome P450 2C9 (CYP2C9), cytochrome P450 2C19 (CYP2C19), Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

العلاقة: https://www.mdpi.com/1999-4923/15/10/2486Test; https://doaj.org/toc/1999-4923Test

الوصول الحر: https://doaj.org/article/a264f6e2b35344d99f434b3337e22602Test

المؤلفون: Tan, Shawn pei feng, Willemin, Marie‐emilie, Snoeys, Jan, Shen, Hong, Rostami‐hodjegan, Amin, Scotcher, Daniel, Galetin, Aleksandra

المصدر: Tan , S P F , Willemin , M , Snoeys , J , Shen , H , Rostami‐hodjegan , A , Scotcher , D & Galetin , A 2023 , ' Development of 4-Pyridoxic Acid PBPK Model to Support Biomarker- Informed Evaluation of OAT1/3 Inhibition and Effect of Chronic Kidney Disease ' , Clinical Pharmacology & Therapeutics . https://doi.org/10.1002/cpt.3029Test

مصطلحات موضوعية: Drug-drug interaction, Endogenous Biomarker, Chronic Kidney Disease, Physiologically-based Pharmacokinetic Modelling, Organic Anion Transporters

وصف الملف: application/pdf

العلاقة: https://research.manchester.ac.uk/en/publications/4f90ccdb-4dc2-4283-933c-90846d41ae99Test

الإتاحة: https://doi.org/10.1002/cpt.3029Test
https://research.manchester.ac.uk/en/publications/4f90ccdb-4dc2-4283-933c-90846d41ae99Test
https://pure.manchester.ac.uk/ws/files/274634385/Clin_Pharma_and_Therapeutics_2023_Tan.pdfTest

المؤلفون: Andrew Lim, Pradeep Sharma, Oleg Stepanov, Venkatesh Pilla Reddy

المصدر: Pharmaceutics; Volume 15; Issue 5; Pages: 1552

مصطلحات موضوعية: pharmacokinetic modelling, PBPK modelling, popPK modelling, pharmacokinetics, pediatrics, monoclonal antibodies, physiologically based pharmacokinetic modelling, population pharmacokinetics

وصف الملف: application/pdf

العلاقة: Pharmacokinetics and Pharmacodynamics; https://dx.doi.org/10.3390/pharmaceutics15051552Test

الإتاحة: https://doi.org/10.3390/pharmaceutics15051552Test

المؤلفون: Tom G. Jacobs, Marika A. de Hoop-Sommen, Thomas Nieuwenstein, Joyce E. M. van der Heijden, Saskia N. de Wildt, David M. Burger, Angela Colbers, Jolien J. M. Freriksen

المصدر: Pharmaceutics; Volume 15; Issue 5; Pages: 1424

مصطلحات موضوعية: HIV, physiologically based pharmacokinetic modelling, chronic kidney disease, paediatrics, emtricitabine, lamivudine

وصف الملف: application/pdf

العلاقة: Pharmacokinetics and Pharmacodynamics; https://dx.doi.org/10.3390/pharmaceutics15051424Test

الإتاحة: https://doi.org/10.3390/pharmaceutics15051424Test

المؤلفون: Min-Soo Kim, Yoo-Kyung Song, Ji-Soo Choi, Hye Young Ji, Eunsuk Yang, Joon Seok Park, Hyung Sik Kim, Min-Joo Kim, In-Kyung Cho, Suk-Jae Chung, Yoon-Jee Chae, Kyeong-Ryoon Lee

المصدر: Pharmaceutics; Volume 15; Issue 3; Pages: 942

مصطلحات موضوعية: enavogliflozin, DWP16001, GCC5694A, sodium-glucose cotransporter 2 inhibitor, diabetes mellitus, physiologically based pharmacokinetic modelling, pharmacokinetics, mechanistic kidney model, in vitro–in vivo extrapolation

وصف الملف: application/pdf

العلاقة: Pharmacokinetics and Pharmacodynamics; https://dx.doi.org/10.3390/pharmaceutics15030942Test

الإتاحة: https://doi.org/10.3390/pharmaceutics15030942Test

المؤلفون: Meslin, Matthieu, Beausoleil, Claire, Zeman, Florence, Antignac, Jean-Philippe, Kolossa-Gehring, Marike, Rousselle, Christophe, Apel, Petra

المساهمون: Direction de l'Evaluation des Risques (DER), Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Institut National de l'Environnement Industriel et des Risques (INERIS), Laboratoire d'étude des Résidus et Contaminants dans les Aliments (LABERCA), École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique (ONIRIS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), German Federal Environmental Agency / Umweltbundesamt (UBA), European Project: 733032,H2020,HBM4EU(2017)

المصدر: ISSN: 2305-6304 ; Toxics ; https://anses.hal.science/anses-03661044Test ; Toxics, 2022, 10 (5), pp.228. ⟨10.3390/toxics10050228⟩ ; https://www.mdpi.com/2305-6304/10/5/228Test.

مصطلحات موضوعية: human biomonitoring (HBM), HBM4EU, internal exposure, biomarkers, endocrine disruptors, bisphenol A (BPA), bisphenol S (BPS), bisphenols, human biomonitoring guidance value (HBM-GV), physiologically based pharmacokinetic modelling (PBPK), risk assessment, [SDV.TOX]Life Sciences [q-bio]/Toxicology, [SDV.EE.SANT]Life Sciences [q-bio]/Ecology, environment/Health, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie

العلاقة: info:eu-repo/semantics/altIdentifier/pmid/35622642; info:eu-repo/grantAgreement//733032/EU/European Human Biomonitoring Initiative/HBM4EU; anses-03661044; https://anses.hal.science/anses-03661044Test; https://anses.hal.science/anses-03661044/documentTest; https://anses.hal.science/anses-03661044/file/Meslin_Toxics_2022.pdfTest; PUBMED: 35622642; WOS: 000803380300001

الإتاحة: https://doi.org/10.3390/toxics10050228Test
https://anses.hal.science/anses-03661044Test
https://anses.hal.science/anses-03661044/documentTest
https://anses.hal.science/anses-03661044/file/Meslin_Toxics_2022.pdfTest

المؤلفون: Karel Allegaert, Mohammad Yaseen Abbasi, Robin Michelet, Olusola Olafuyi

المصدر: Pharmaceutics; Volume 14; Issue 9; Pages: 1957

مصطلحات موضوعية: physiologically based pharmacokinetic modelling, propofol, low cardiac output, pharmacokinetics, neonate, developmental pharmacology, asphyxia, hypothermia, pediatrics

وصف الملف: application/pdf

العلاقة: Pharmacokinetics and Pharmacodynamics; https://dx.doi.org/10.3390/pharmaceutics14091957Test

الإتاحة: https://doi.org/10.3390/pharmaceutics14091957Test