المؤلفون: Wouter J. Venema, Sanne Hiddingh, Jorg van Loosdregt, John Bowes, Brunilda Balliu, Joke H. de Boer, Jeannette Ossewaarde-van Norel, Susan D. Thompson, Carl D. Langefeld, Aafke de Ligt, Lars T. van der Veken, Peter H.L. Krijger, Wouter de Laat, Jonas J.W. Kuiper

المصدر: Cell Genomics, Vol 4, Iss 1, Pp 100460- (2024)

مصطلحات موضوعية: ERAP2, GWAS, autoimmunity, SNP, eQTL, rs2248374, Genetics, QH426-470, Internal medicine, RC31-1245

وصف الملف: electronic resource

العلاقة: http://www.sciencedirect.com/science/article/pii/S2666979X2300304XTest; https://doaj.org/toc/2666-979XTest

الوصول الحر: https://doaj.org/article/ef5055cff96b4f289ee5f7103baea2baTest

المؤلفون: Wouter J. Venema, Sanne Hiddingh, Jorg van Loosdregt, John Bowes, Brunilda Balliu, Joke H. de Boer, Jeanette Ossewaarde-van Norel, Susan. D. Thompson, Carl D. Langefeld, Lars T. van der Veken, Konstantinos Sofiadis, Peter H.L. Krijger, Wouter de Laat, Jonas J.W. Kuiper

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::443217bec5198c863a1b600a51d5098bTest
https://doi.org/10.1101/2023.03.03.530973Test

المؤلفون: Ruiqi Han, Yike Huang, Iwan Vaandrager, Amin Allahyar, Mikhail Magnitov, Marjon J.A.M. Verstegen, Elzo de Wit, Peter H.L. Krijger, Wouter de Laat

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::549c3766e744f2f609090e917c46ece7Test
https://doi.org/10.1101/2023.01.04.522689Test

المؤلفون: Bingtao Hao, Heinz Jacobs, Colin Pritchard, Martijn van Baalen, Peter H.L. Krijger, Ron M. Kerkhoven, Iris de Rink, Mir Farshid Alemdehy, Muhammad Assad Aslam, Ika Nurzijah, Fitriari Izzatunnisa Muhaimin, Jane A. Skok, Paul C.M. van den Berk

المصدر: Proceedings of the National Academy of Sciences of the United States of America

مصطلحات موضوعية: early B cell development, Biology, 03 medical and health sciences, Exon, 0302 clinical medicine, Immunology and Inflammation, allelic exclusion, read-through translation, medicine, Animals, RNA, Messenger, Allele, B cell, Alleles, 030304 developmental biology, 0303 health sciences, Messenger RNA, B-Lymphocytes, Multidisciplinary, Ig heavy chain checkpoint, Precursor Cells, B-Lymphoid, RNA, Reproducibility of Results, Biological Sciences, PreB cell antigen receptor, Molecular biology, Stop codon, Mice, Inbred C57BL, Allelic exclusion, medicine.anatomical_structure, Genetic Loci, Immunoglobulin heavy chain, Immunoglobulin Heavy Chains, 030217 neurology & neurosurgery, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::903aeee2d2439e85bc4ac05ce2429b1bTest
http://europepmc.org/articles/PMC7733823Test

المؤلفون: Joost Vermaat, Tom van Wezel, Paula J P de Vree, Wouter de Laat, Bauke Ylstra, Amin Allahyar, Marieke Simonis, Harma Feitsma, Adrien S. J. Melquiond, Max van Min, Agata Rakszewska, Erik Splinter, Daphne de Jong, Joost Swennenhuis, Milan Sharma, Mehmet Yilmaz, Arjan Diepstra, Roos J Leguit, Robert van der Geize, Phylicia Stathi, Karima Hajo, Nathalie J. Hijmering, Mark Pieterse, Marjon J.A.M. Verstegen, Peter H.L. Krijger, Ruud W J Meijers, G Tjitske Los-de Vries, Léon C van Kempen, Arjen H.G. Cleven

المساهمون: Pathology, VU University medical center, CCA - Imaging and biomarkers, Hubrecht Institute for Developmental Biology and Stem Cell Research, Stem Cell Aging Leukemia and Lymphoma (SALL)

المصدر: Nature Communications, 12(1):3361. Nature Publishing Group
Nature Communications
Nature Communications, 12(1). Nature Publishing Group
Nature Communications, 12(1). NATURE PORTFOLIO
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Allahyar, A, Pieterse, M, Swennenhuis, J, Los-de Vries, G T, Yilmaz, M, Leguit, R, Meijers, R W J, van der Geize, R, Vermaat, J, Cleven, A, van Wezel, T, Diepstra, A, van Kempen, L O C, Hijmering, N J, Stathi, P, Sharma, M, Melquiond, A S J, de Vree, P J P, Verstegen, M J A M, Krijger, P H L, Hajo, K, Simonis, M, Rakszewska, A, van Min, M, de Jong, D, Ylstra, B, Feitsma, H, Splinter, E & de Laat, W 2021, ' Robust detection of translocations in lymphoma FFPE samples using targeted locus capture-based sequencing ', Nature Communications, vol. 12, no. 1, 3361 . https://doi.org/10.1038/s41467-021-23695-8Test

مصطلحات موضوعية: 0301 basic medicine, Tissue Fixation, Lymphoma, Non-Hodgkin/diagnosis, Genes, myc, General Physics and Astronomy, Chromosomal translocation, MYC, Translocation, Genetic, 0302 clinical medicine, Cancer genomics, bcl-2/genetics, B-Cell/diagnosis, B-cell lymphoma, In Situ Hybridization, In Situ Hybridization, Fluorescence, Gene Rearrangement, High-Throughput Nucleotide Sequencing/methods, Multidisciplinary, Paraffin Embedding, medicine.diagnostic_test, Genes, bcl-2/genetics, Lymphoma, Non-Hodgkin, REARRANGEMENTS, In Situ Hybridization, Fluorescence/methods, High-Throughput Nucleotide Sequencing, Proto-Oncogene Proteins c-bcl-6/genetics, 030220 oncology & carcinogenesis, Proto-Oncogene Proteins c-bcl-6, Biomedical engineering, EXPRESSION, Lymphoma, B-Cell, Lymphoma, Non-Hodgkin/diagnosis, Paraffin Embedding/methods, Science, Translocation, Locus (genetics), Computational biology, Biology, Fluorescence/methods, Sensitivity and Specificity, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Genetic, medicine, Humans, Genes, myc/genetics, Retrospective Studies, business.industry, Lymphoma, B-Cell/diagnosis, Cancer, B-CELL LYMPHOMA, Computational Biology, Reproducibility of Results, General Chemistry, Gene rearrangement, Computational Biology/methods, medicine.disease, Personalized medicine, Genes, bcl-2, 030104 developmental biology, Genes, myc/genetics, Tissue Fixation/methods, business, Fluorescence in situ hybridization

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f015170cc76e934c99a06da52084f3baTest
https://research.vumc.nl/en/publications/dbd7c41c-2950-4947-b268-32207673d8fdTest

المؤلفون: Teodora Filipovska, Zaria de Andrade dos Ramos, Marjon J.A.M. Verstegen, Niels J. Rinzema, Stefan van der Elst, Peter H.L. Krijger, Sjoerd J. D. Tjalsma, Ruiqi Han, Anna-Karina Felder, Konstantinos Sofiadis, Wouter de Laat, Yuva Oz, Christian Valdes-Quezada

مصطلحات موضوعية: Cohesin, Transcription (biology), CTCF, Gene silencing, Promoter, Biology, Enhancer, Transcription factor, Chromatin, Cell biology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::4876d05b47a57dd0f54464338106fe7cTest
https://doi.org/10.1101/2021.10.05.463209Test

المؤلفون: Wouter de Laat, Anton van Weert, Sanne Boersma, Peter H.L. Krijger, Lieke I P M Donders, Jo Vandesompele, Rene J T M Roymans, Stefan Meijer, Francesca Mattiroli, Tim A. Hoek, Pim W. Toonen, Edwin Dekker, Monique Nijhuis, Thomas W van Ravesteyn, Ive Logister, Fred J Dom, Maaike Broeders, Mark Pieterse, Lieven B J van der Velden, Martijn Bosch, Bram M.P. Verhagen, Marvin E. Tanenbaum, Marjon J.A.M. Verstegen, Jeroen H.B. van de Bovenkamp, Rob Ruijtenbeek

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Nature Biotechnology, 39(10), 1182-1184. Nature Publishing Group

مصطلحات موضوعية: 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), SARS-CoV-2, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS-CoV-2/pathogenicity, Biomedical Engineering, Public-Private Sector Partnership, COVID-19, Bioengineering, Public administration, Applied Microbiology and Biotechnology, Public-Private Sector Partnerships, Public–private partnership, Molecular Medicine, Humans, Business, Delivery of Health Care, Biotechnology, COVID-19/epidemiology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abf13f7adf6a0ecc214d0a147ddeb3bfTest
https://pure.knaw.nl/portal/en/publications/4f9be3a2-c913-455b-aeeb-b0f8bf0d8146Test

المؤلفون: Anna-Karina Felder, Floor van der Vegt, Christian Valdes-Quezada, Wouter de Laat, Esther C.H. Uijttewaal, Amin Allahyar, Peter H.L. Krijger, E.S. Vos, Yike Huang, Marjon J.A.M. Verstegen

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Molecular Cell, 81(15), 3082-3095.e6. Cell Press
Nature Genetics

مصطلحات موضوعية: CCCTC-Binding Factor, Enhancer Elements, Chromosomal Proteins, Non-Histone, Transcription Factors/genetics, Gene Expression, Cell Cycle Proteins, Biology, CCCTC-Binding Factor/genetics, Promoter Regions, Chromosomal Proteins, Non-Histone/genetics, 03 medical and health sciences, Nuclear Receptor Coactivator 2, Mice, 0302 clinical medicine, Genetic, Transcription (biology), Animals, Enhancer, Promoter Regions, Genetic, Molecular Biology, 030304 developmental biology, Nuclear Receptor Coactivator 2/genetics, Regulation of gene expression, Cohesin loading, Cell Cycle Proteins/genetics, 0303 health sciences, Cohesin, Chromatin/genetics, RNA-Binding Proteins, Promoter, Mouse Embryonic Stem Cells, Cell Biology, RNA-Binding Proteins/genetics, Chromatin, Cell biology, DNA-Binding Proteins, Chromosomal Proteins, Enhancer Elements, Genetic, CTCF, Non-Histone/genetics, 030217 neurology & neurosurgery, DNA-Binding Proteins/genetics, Transcription Factors

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8281448c446a0236b43ea83fe6982de5Test
https://pure.knaw.nl/portal/en/publications/b95644d7-6943-4241-ba98-bb921ebeb393Test

المؤلفون: Marjon J.A.M. Verstegen, Jeroen de Ridder, Ivo Renkens, Carlo Vermeulen, Wigard P. Kloosterman, Wouter de Laat, Britta A M Bouwman, Roy Straver, Peter H.L. Krijger, Christian Valdes-Quezada, Geert Geeven, Amin Allahyar

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Nature Protocols, 15(2), 364-397. Nature Publishing Group
Nature Protocols, 15(2), 364. Nature Publishing Group

مصطلحات موضوعية: Sequence analysis, Concatemer, Computer science, Molecular Conformation, Computational biology, Biochemistry, Chromatin structure, General Biochemistry, Genetics and Molecular Biology, DNA sequencing, Chromosome conformation capture, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Journal Article, Humans, 030304 developmental biology, 0303 health sciences, Biochemistry, Genetics and Molecular Biology(all), Inverse polymerase chain reaction, Sequence Analysis, DNA, Chromatin, DNA/methods, Data processing, chemistry, Sequence Analysis, DNA/methods, Next-generation sequencing, Nanopore sequencing, Chromatin/chemistry, K562 Cells, Sequence Analysis, 030217 neurology & neurosurgery, DNA, Genetics and Molecular Biology(all)

وصف الملف: image/pdf; text/plain

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e3fdcee30fb37bdcefb214e2021ae2Test
https://pure.knaw.nl/portal/en/publications/28abd704-3741-4ef3-9d0d-4a1562c34ceeTest

المؤلفون: Carlo Vermeulen, Marjon J.A.M. Verstegen, Wigard P. Kloosterman, Mark Pieterse, Hans Teunissen, Britta A M Bouwman, Judith H.I. Haarhuis, Amin Allahyar, Peter H.L. Krijger, Elzo de Wit, Jeroen de Ridder, Ivo Renkens, Roy Straver, Benjamin D. Rowland, Kees Jalink, Wouter de Laat, Geert Geeven, Melissa van Kranenburg

المساهمون: Hubrecht Institute for Developmental Biology and Stem Cell Research

المصدر: Nature Genetics, 50(8), 1151-1160. Nature Publishing Group
Nature Genetics
Nature Genetics, 50(8), 1151. Nature Publishing Group

مصطلحات موضوعية: 0301 basic medicine, CCCTC-Binding Factor, Cohesin, Genomics, beta-Globins, Computational biology, Regulatory Sequences, Nucleic Acid, Biology, Genome, Chromatin, Folding (chemistry), Mice, 03 medical and health sciences, Enhancer Elements, Genetic, 030104 developmental biology, Genetics, Animals, Nucleic Acid Conformation, Nanopore sequencing, Enhancer, Gene, Alleles

وصف الملف: image/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cbb369ac2fa5aeaeaf3af5decaac55Test
https://doi.org/10.1038/s41588-018-0161-5Test