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1
المؤلفون: Roger Olsson, Peter Aadal Nielsen, Karin Hellman, Fredrik Ek
المصدر: ACS Chemical Neuroscience. 7:668-680
مصطلحات موضوعية: Drug, Physiology, Cognitive Neuroscience, Metabolite, media_common.quotation_subject, Grasshoppers, Biology, Pharmacology, Blood–brain barrier, 030226 pharmacology & pharmacy, Biochemistry, Permeability, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, In vivo, medicine, Animals, Clozapine, media_common, Brain, Cell Biology, General Medicine, medicine.anatomical_structure, chemistry, Blood-Brain Barrier, Models, Animal, Efflux, 030217 neurology & neurosurgery, Drug metabolism, Ex vivo, Antipsychotic Agents, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3dd5549e77d00856e6ddb529575220Test
https://doi.org/10.1021/acschemneuro.6b00024Test -
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المؤلفون: Steen Honoré Hansen, Peter Aadal Nielsen, Olga Andersson, Karin Hellman, Lassina Badolo, Niels Svenstrup, Gunnar Andersson, Line Olsen
المصدر: Journal of Pharmacology and Experimental Therapeutics. 346:211-218
مصطلحات موضوعية: Central nervous system, ATP-binding cassette transporter, Grasshoppers, In Vitro Techniques, Blood–brain barrier, Mass Spectrometry, Permeability, Madin Darby Canine Kidney Cells, Dogs, biology.animal, Drug Discovery, medicine, Animals, ATP Binding Cassette Transporter, Subfamily B, Member 1, P-glycoprotein, Pharmacology, biology, Drug discovery, Brain, Vertebrate, In vitro, medicine.anatomical_structure, Verapamil, Blood-Brain Barrier, Models, Animal, biology.protein, Biophysics, Molecular Medicine, Neuroscience, Ex vivo, Central Nervous System Agents, Chromatography, Liquid
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb0ae87e7b28924995de52b3cfa040b9Test
https://doi.org/10.1124/jpet.113.205476Test -
3
المؤلفون: Jesper Mosolff Mathiesen, Jean-Marie Receveur, Thomas Högberg, Marie Grimstrup, Øystein Rist, Thomas M. Frimurer, Peter Aadal Nielsen
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:1638-1641
مصطلحات موضوعية: Models, Molecular, Pyrimidine, Nitrogen, Stereochemistry, Receptors, Prostaglandin, Clinical Biochemistry, Substituent, Pharmaceutical Science, Biochemistry, Cell Line, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Humans, Structure–activity relationship, Imidazole, Molecule, Computer Simulation, Benzhydryl Compounds, Receptors, Immunologic, Binding site, Molecular Biology, Binding Sites, Hydrogen bond, Organic Chemistry, Imidazoles, Hydrogen Bonding, Rats, Thiazoles, Pyrimidines, chemistry, Intramolecular force, Molecular Medicine
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1336edb6f12ba1051196a9ddb767cb70Test
https://doi.org/10.1016/j.bmcl.2010.01.092Test -
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المؤلفون: Cooper Martin, Pia Karina Nørregaard, Jean-Michel Linget, Emelie Bjurling, Jean-Marie Receveur, Peter Aadal Nielsen, Anthony Murray, Thomas Högberg
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:453-457
مصطلحات موضوعية: Drug Inverse Agonism, Nitrile, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Pharmacology, Pyrazole, Biochemistry, Polar surface area, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, Receptor, Cannabinoid, CB1, Rimonabant, Amide, Drug Discovery, medicine, Animals, Inverse agonist, Obesity, Molecular Biology, ADME, Body Weight, Organic Chemistry, Amides, Rats, chemistry, Blood-Brain Barrier, Pyrazoles, Molecular Medicine, Anti-Obesity Agents, Protein Binding, medicine.drug
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1d4234d82a51c4fa6c2b46aad74f0eTest
https://doi.org/10.1016/j.bmcl.2009.12.003Test -
5
المصدر: Biochimica et biophysica acta. 1850(12)
مصطلحات موضوعية: biology, Sequence Homology, Amino Acid, Drug discovery, Molecular Sequence Data, Biophysics, Grasshoppers, Bioinformatics, biology.organism_classification, Biochemistry, Models, Biological, Cell biology, Transcriptome, In vivo, biology.protein, Animals, Efflux, ATP Binding Cassette Transporter, Subfamily B, Member 1, Amino Acid Sequence, Drosophila melanogaster, Molecular Biology, Peptide sequence, Locust, Phylogeny, P-glycoprotein
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eb046161ba1c527d595f05ea8b6d831Test
https://pubmed.ncbi.nlm.nih.gov/26363463Test -
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المؤلفون: Charlotte Gabel-Jensen, Peter Aadal Nielsen, Lassina Badolo, Line Olsen, Steen Honoré Hansen
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 42(7)
مصطلحات موضوعية: Pharmacology, Male, animal structures, CYP3A4, Metabolite, Pharmaceutical Science, Transporter, Grasshoppers, Biology, biology.organism_classification, Substrate Specificity, Metabolic pathway, chemistry.chemical_compound, chemistry, Biochemistry, In vivo, Animals, Cytochrome P-450 CYP3A, Humans, Efflux, Ex vivo, Locust
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ee0a12229eef662602b085c4e10a87Test
https://pubmed.ncbi.nlm.nih.gov/24778367Test -
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المؤلفون: Rik Verdonck, Liesbeth Badisco, Gunnar Andersson, Olga Andersson, Steen Honoré Hansen, Jozef Vanden Broeck, Ane Håkansson Hansen, Karin Hellman, Peter Aadal Nielsen, N. Joan Abbott, Line Olsen
المصدر: Pharmacology Research & Perspectives
Pharmacology research & perspectives; 2(4), pp 00050-00050 (2014)مصطلحات موضوعية: animal structures, biology, Transporter, Pharmacology and Toxicology, Original Articles, Pharmacology, biology.organism_classification, efflux transporter, Rhodamine 123, Cell biology, chemistry.chemical_compound, Neurology, chemistry, Brain–barrier permeability, In vivo, insect brain barrier, Pgp-transporter, biology.protein, screening model, Schistocerca, General Pharmacology, Toxicology and Pharmaceutics, Desert locust, Ex vivo, Locust, P-glycoprotein
وصف الملف: text/html; Print-Electronic
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7049a6847c5bce62c382cb0fea7575eTest
https://pubmed.ncbi.nlm.nih.gov/25505597Test -
8
المصدر: Journal of the American Chemical Society. 123:2003-2006
مصطلحات موضوعية: Acid-Base Equilibrium, Magnetic Resonance Spectroscopy, Aqueous solution, Protein Conformation, Hydrogen bond, Chemistry, education, Ab initio, Water, Protonation, General Chemistry, Nuclear magnetic resonance spectroscopy, Carbon-13 NMR, Biochemistry, Polarizable continuum model, Catalysis, Solutions, Colloid and Surface Chemistry, Models, Chemical, Computational chemistry, Pipecolic Acids, Titration
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b703a8563a993f329246d73ccf8e447fTest
https://doi.org/10.1021/ja002926cTest -
9
المؤلفون: Peter Aadal Nielsen, Tommy Liljefors
المصدر: Journal of Computer-Aided Molecular Design. 15:753-763
مصطلحات موضوعية: Kainic acid, Aqueous solution, Kainate receptor, AMPA receptor, Ligand (biochemistry), Computer Science Applications, Accessible surface area, chemistry.chemical_compound, Crystallography, chemistry, Drug Discovery, Physical and Theoretical Chemistry, Receptor, Conformational isomerism
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::e376fd38fedd7706c1e6dbe48bdf65f9Test
https://doi.org/10.1023/a:1012414702198Test -
10
المصدر: Journal of the American Chemical Society. 122:3151-3155
مصطلحات موضوعية: Quantitative Biology::Biomolecules, Aqueous solution, Electronic correlation, Chemistry, Solvation, Thermodynamics, General Chemistry, Biochemistry, Polarizable continuum model, Catalysis, chemistry.chemical_compound, Colloid and Surface Chemistry, Computational chemistry, Intramolecular force, Zwitterion, Physics::Atomic and Molecular Clusters, Molecule, Physics::Chemical Physics, Conformational isomerism
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_________::8b625d86bfbe85a2fc23e6dca09b960dTest
https://doi.org/10.1021/ja992902Test+